Title: The 10 Best Hotels Near Sanford-Burnham Medical Research Institute, Orlando from CA $84 | Expedia.ca [Lake Nona Travel Guide](https://expedia.ca/Orlando-Lake-Nona.dx6209488)[Sanford-Burnham Medical Research Institute Car Rentals](https://expedia.ca/Car-Rentals-In-Sanford-Burnham-Medical-Research-Institute.d6197084.Car-Rental-Guide)[Sanford-Burnham Medical Research Institute Vacations](https://expedia.ca/Sanford-Burnham-Medical-Research-Institute-Lake-Nona.d6197084.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6197084&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 18 - Jan 19](https://www.expedia.ca/Hotel-Search?regionId=6197084&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6197084&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6197084&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Sanford-Burnham Medical Research Institute hotels ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/72000000/71690000/71682000/71681962/77d6c1ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/72000000/71690000/71682000/71681962/c72621f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hiking](https://images.trvl-media.com/lodging/72000000/71690000/71682000/71681962/d8be13f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/72000000/71690000/71682000/71681962/2ceec635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Nona Wave Hotel [](https://www.expedia.ca/Orlando-Hotels-Lake-Nona-Wave-Hotel.h71681962.Hotel-Information) 2.8 km from Sanford-Burnham Medical Research Institute 9.6/10 Exceptional (1,105 reviews) "Great property, clean rooms and good restaurants" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krystoff CA $322 CA $366 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Orlando-Hotels-Lake-Nona-Wave-Hotel.h71681962.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/97000000/96730000/96727700/96727633/57e4eb0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/97000000/96730000/96727700/96727633/efcf1bcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/97000000/96730000/96727700/96727633/cd6a9ba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/97000000/96730000/96727700/96727633/w4000h2664x0y0-9ee7de37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Orlando Lake Nona [](https://www.expedia.ca/Orlando-Hotels-Aloft-Orlando-Lake-Nona.h96727633.Hotel-Information) 2 km from Sanford-Burnham Medical Research Institute 9.8/10 Exceptional (296 reviews) "Our stay was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kendra CA $237 CA $266 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Orlando-Hotels-Aloft-Orlando-Lake-Nona.h96727633.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/12000000/11960000/11951100/11951044/ceee955c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/12000000/11960000/11951100/11951044/3693a0d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/12000000/11960000/11951100/11951044/dac1f16b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/12000000/11960000/11951100/11951044/31f04f48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Orlando Lake Nona [](https://www.expedia.ca/Orlando-Hotels-Courtyard-Orlando-Lake-Nona.h11951044.Hotel-Information) 1.2 km from Sanford-Burnham Medical Research Institute 9.4/10 Exceptional (604 reviews) "Clean room and pleasant staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $235 CA $267 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Orlando-Hotels-Courtyard-Orlando-Lake-Nona.h11951044.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/710000/700200/700148/5afe7553.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Non Smoking](https://images.trvl-media.com/lodging/1000000/710000/700200/700148/2304a9fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/710000/700200/700148/88bb6b54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/710000/700200/700148/8ab74dff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Orlando International Airport [](https://www.expedia.ca/Orlando-Hotels-Sleep-Inn-Suites-Orlando-International-Airport.h700148.Hotel-Information) 11.5 km from Sanford-Burnham Medical Research Institute 8.0/10 Very good (1,330 reviews) "Front desk person was personable and VERY helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jackie CA $99 CA $111 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Orlando-Hotels-Sleep-Inn-Suites-Orlando-International-Airport.h700148.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/27000000/26940000/26939400/26939377/88bf772e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/27000000/26940000/26939400/26939377/4b1af59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/27000000/26940000/26939400/26939377/871fceab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/27000000/26940000/26939400/26939377/b668a35e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites - Orlando - Southeast by IHG [](https://www.expedia.ca/Orlando-Hotels-Holiday-Inn-Express-Suites-Orlando-Lake-Nona-Area.h26939377.Hotel-Information) 5 km from Sanford-Burnham Medical Research Institute 9.2/10 Wonderful (1,005 reviews) "Very nice hotel and easy to find. Great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marc CA $200 CA $225 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Orlando-Hotels-Holiday-Inn-Express-Suites-Orlando-Lake-Nona-Area.h26939377.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/b4932735.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/80f72df0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/ee176170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/0f30a2a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Orlando Airport North [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Airport-North.h120304.Hotel-Information) Airport North, 10.6 km from Sanford-Burnham Medical Research Institute 7.4/10 Good (1,052 reviews) "Hotel is very nice and staff very helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $132 CA $149 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Airport-North.h120304.Hotel-Information) ![Suite, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/460000/455400/455359/13049557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/460000/455400/455359/91158b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/455400/455359/w3836h2560x4y4-812a7872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/460000/455400/455359/w3836h2560x4y4-13f194ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta Essential Orlando Airport [](https://www.expedia.ca/Orlando-Hotels-Sonesta-Essential-Orlando.h455359.Hotel-Information) 11.4 km from Sanford-Burnham Medical Research Institute 8.0/10 Very good (393 reviews) "Room was clean and staff was friendly and helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tatiana Francine CA $105 CA $118 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Orlando-Hotels-Sonesta-Essential-Orlando.h455359.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/892800/892720/a741e368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/900000/892800/892720/5689363f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/900000/892800/892720/d2b4674d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/892800/892720/e9b64806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Heritage Park [](https://www.expedia.ca/Orlando-Hotels-Quality-Inn-Suites-Heritage-Park.h892720.Hotel-Information) 11 km from Sanford-Burnham Medical Research Institute 8.2/10 Very good (1,003 reviews) "Nice hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nick CA $112 CA $128 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Orlando-Hotels-Quality-Inn-Suites-Heritage-Park.h892720.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/970000/967500/967413/cecab119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Studio Suite, 1 King Bed, Non Smoking, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/1000000/970000/967500/967413/fb74808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/967500/967413/75a741f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/970000/967500/967413/6c50b521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham - Orlando International Airport [](https://www.expedia.ca/Orlando-Hotels-Wingate-By-Wyndham-Orlando-International-Airport.h967413.Hotel-Information) Airport North, 10.9 km from Sanford-Burnham Medical Research Institute 8.8/10 Excellent (3,772 reviews) "Great service at airport, clean rooms and breakfast was good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) tammy CA $138 CA $156 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Orlando-Hotels-Wingate-By-Wyndham-Orlando-International-Airport.h967413.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27300/27213/0a09e445.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/27300/27213/0c360557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27300/27213/762c6ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/27300/27213/2a5900d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Orlando Airport West [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-By-Wyndham-Orlando-Airport-West.h27213.Hotel-Information) 10.7 km from Sanford-Burnham Medical Research Institute 6.0/10 (2,628 reviews) "Clean room, and staff very nice and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leonel CA $83 CA $93 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Orlando-Hotels-La-Quinta-Inn-By-Wyndham-Orlando-Airport-West.h27213.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6900/6856/94c09ef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6900/6856/9a4b78a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9 AM to 10 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/6900/6856/8ab1ecf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9 AM to 10 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/6900/6856/22d963fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Orlando Palms Hotel [](https://www.expedia.ca/Orlando-Hotels-The-London-Orlando-At-The-Florida-Mall.h6856.Hotel-Information) 13.9 km from Sanford-Burnham Medical Research Institute 7.6/10 Good (2,281 reviews) "Very clean room Room was spacious and beautiful Very good hotel to stay Good location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) wesner CA $60 CA $84 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Orlando-Hotels-The-London-Orlando-At-The-Florida-Mall.h6856.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/1000000/10000/800/751/1c998217.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/800/751/5e36497a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/800/751/398d76cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/800/751/1b9e2181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Orlando International Airport by IHG [](https://www.expedia.ca/Orlando-Hotels-Holiday-Inn-Orlando-International-Airport.h751.Hotel-Information) Airport North, 10.6 km from Sanford-Burnham Medical Research Institute 8.6/10 Excellent (1,336 reviews) "Comfortable bed, courteous staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Betty CA $164 CA $185 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Orlando-Hotels-Holiday-Inn-Orlando-International-Airport.h751.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2800/2754/928976cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/2800/2754/b16b92f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/10000/2800/2754/w5752h3835x5y5-c0622ec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2800/2754/a9de6c18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Orlando International Airport [](https://www.expedia.ca/Orlando-Hotels-Hyatt-Regency-Orlando-International-Airport.h2754.Hotel-Information) 7.4 km from Sanford-Burnham Medical Research Institute 9.4/10 Exceptional (3,898 reviews) "Great room and fantastic location with valet parking for entire trip!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) dawn CA $291 CA $327 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Orlando-Hotels-Hyatt-Regency-Orlando-International-Airport.h2754.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/61000000/60520000/60517400/60517339/a3e034f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/61000000/60520000/60517400/60517339/bcc37d1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/61000000/60520000/60517400/60517339/56cb6aec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/61000000/60520000/60517400/60517339/e1d8ed2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Orlando Airport [](https://www.expedia.ca/Orlando-Hotels-Cambria-Hotel-Orlando-Airport.h60517339.Hotel-Information) 10.6 km from Sanford-Burnham Medical Research Institute 8.8/10 Excellent (1,951 reviews) "Clean room friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Precious CA $158 CA $178 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Orlando-Hotels-Cambria-Hotel-Orlando-Airport.h60517339.Hotel-Information) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/7100/7031/b1c4363b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/7100/7031/f4911a77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/10000/7100/7031/7dd981da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathroom sink](https://images.trvl-media.com/lodging/1000000/10000/7100/7031/7b5b177e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Orlando Airport [](https://www.expedia.ca/Orlando-Hotels-Quality-Inn-Suites-Orlando-Airport.h7031.Hotel-Information) Belle Isle, 11.3 km from Sanford-Burnham Medical Research Institute 6.8/10 (1,909 reviews) "Love this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $93 CA $106 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Orlando-Hotels-Quality-Inn-Suites-Orlando-Airport.h7031.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327400/327322/dcc2b70c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/330000/327400/327322/fee6a1f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327400/327322/91f01ca9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/330000/327400/327322/dffbfa04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Orlando International Airport by IHG [](https://www.expedia.ca/Orlando-Hotels-Holiday-Inn-Express-Orlando-International-Airport.h327322.Hotel-Information) 10.6 km from Sanford-Burnham Medical Research Institute 9.0/10 Wonderful (1,870 reviews) "Great hotel." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Rory CA $158 CA $178 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Orlando-Hotels-Holiday-Inn-Express-Orlando-International-Airport.h327322.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/61000000/60340000/60334000/60333930/e5ac9c00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/61000000/60340000/60334000/60333930/0dde599f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/61000000/60340000/60334000/60333930/ddbd347f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/61000000/60340000/60334000/60333930/dced7b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Kissimmee North [](https://www.expedia.ca/Orlando-Hotels-Hampton-Inn-Kissimmee-North.h60333930.Hotel-Information) 11.6 km from Sanford-Burnham Medical Research Institute 9.6/10 Exceptional (618 reviews) "Clean room, great breakfast options and clean breakfast area, friendly and helpful staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randi Lee CA $159 CA $180 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Orlando-Hotels-Hampton-Inn-Kissimmee-North.h60333930.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816796/8bb5bf00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816796/e741957d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816796/155f0cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816796/8750841c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Orlando Southeast Nona [](https://www.expedia.ca/Orlando-Hotels-Hampton-Inn-Orlando-Lake-Nona.h92816796.Hotel-Information) 4.6 km from Sanford-Burnham Medical Research Institute 9.2/10 Wonderful (633 reviews) "Great newer hotel close to the airport. All was clean, modern, nicely decorated; good vibe overall. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dmitri CA $216 CA $243 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Orlando-Hotels-Hampton-Inn-Orlando-Lake-Nona.h92816796.Hotel-Information) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing Accessible)](https://images.trvl-media.com/lodging/1000000/130000/120400/120303/eaaaaee9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/120400/120303/b9874f09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/120400/120303/9ad85eb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/120400/120303/c9e90a56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Suites Orlando Airport [](https://www.expedia.ca/Orlando-Hotels-Ramada-By-Wyndham-Suites-Orlando-Airport.h120303.Hotel-Information) Airport North, 10.2 km from Sanford-Burnham Medical Research Institute 8.4/10 Very good (5,270 reviews) "Great stay overall" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bibi CA $151 CA $170 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Orlando-Hotels-Ramada-By-Wyndham-Suites-Orlando-Airport.h120303.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/39070000/39065100/39065095/c574100e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/40000000/39070000/39065100/39065095/88896d87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/40000000/39070000/39065100/39065095/91d93c2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39070000/39065100/39065095/cc14cd88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### avid hotel Orlando International Airport by IHG [](https://www.expedia.ca/Orlando-Hotels-Avid-Hotels-Orlando-International-Airport.h39065095.Hotel-Information) 10.7 km from Sanford-Burnham Medical Research Institute 9.2/10 Wonderful (2,086 reviews) "Great quick stay for a good value!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pamela CA $156 CA $175 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Orlando-Hotels-Avid-Hotels-Orlando-International-Airport.h39065095.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-01&endDate=2026-02-02®ionId=6197084&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Sanford-Burnham Medical Research Institute Hotel Reviews ![Holiday Inn Express & Suites - Orlando - Southeast by IHG](https://images.trvl-media.com/lodging/27000000/26940000/26939400/26939377/4b1af59a_y.jpg) ### Holiday Inn Express & Suites - Orlando - Southeast by IHG 10/10 Excellent "Everything was so clean. The staff was my favorite part. There was ALWAYS a desk person present at the desk which I LOVED!!! I hate to ring a bell or call out for help to someone in”the back”. The staff was super friendly and helpful as well. Will definitely stay here again the next time we come to visit my son. " [](https://expedia.ca/Orlando-Hotels-Holiday-Inn-Express-Suites-Orlando-Lake-Nona-Area.h26939377.Hotel-Information) ![Hyatt Regency Orlando International Airport](https://images.trvl-media.com/lodging/1000000/10000/2800/2754/acaa1e8b_y.jpg) ### Hyatt Regency Orlando International Airport 10/10 Excellent "The room was clean and spacious. The pool area was also nice and clean. We did not eat breakfast offered by the hotel as our flight was early but the restaurants offered in the airport were good as well" [](https://expedia.ca/Orlando-Hotels-Hyatt-Regency-Orlando-International-Airport.h2754.Hotel-Information) ![Hampton Inn Orlando Southeast Nona](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816796/8bb5bf00_y.jpg) ### Hampton Inn Orlando Southeast Nona 10/10 Excellent "Great newer hotel close to the airport. All was clean, modern, nicely decorated; good vibe overall. " [](https://expedia.ca/Orlando-Hotels-Hampton-Inn-Orlando-Lake-Nona.h92816796.Hotel-Information) ![Ramada by Wyndham Suites Orlando Airport](https://images.trvl-media.com/lodging/1000000/130000/120400/120303/2eaf4a61_y.jpg) ### Ramada by Wyndham Suites Orlando Airport 10/10 Excellent "Clean room, great amenities " [](https://expedia.ca/Orlando-Hotels-Ramada-By-Wyndham-Suites-Orlando-Airport.h120303.Hotel-Information) ![Home2 Suites by Hilton Orlando Southeast Nona](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816795/db34c976_y.jpg) ### Home2 Suites by Hilton Orlando Southeast Nona 10/10 Excellent "Everything was clean!" [](https://expedia.ca/Orlando-Hotels-Home2-Suites-Orlando-Lake-Nona.h92816795.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Orlando Airport North](https://images.trvl-media.com/lodging/1000000/130000/120400/120304/4fbafd8c_y.jpg) ### La Quinta Inn & Suites by Wyndham Orlando Airport North 10/10 Excellent "Staff was great, room was clean, its a great location. My only issue was whenever we showered the water was always hot. " [](https://expedia.ca/Orlando-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orlando-Airport-North.h120304.Hotel-Information) ![Beautiful Summer Home](https://images.trvl-media.com/lodging/37000000/36780000/36773800/36773718/ae3e3432_y.jpg) ### Beautiful Summer Home 10/10 Excellent "House is gorgeous!!! Great location, close to everything! The swimming pool is fantastic and any and all questions were answered quickly. Will definitely be back :) " [](https://expedia.ca/Orlando-Hotels-New-Listing-Beautiful-Summer-Home.h36773718.Hotel-Information) ![Lake Nona Wave Hotel](https://images.trvl-media.com/lodging/72000000/71690000/71682000/71681962/2ceec635_y.jpg) ### Lake Nona Wave Hotel 10/10 Excellent "Beautiful lobby courteous valet and staff" [](https://expedia.ca/Orlando-Hotels-Lake-Nona-Wave-Hotel.h71681962.Hotel-Information) ![Mi Casa Es Su Casa!!🏡 4 Bdrm home with pool](https://images.trvl-media.com/lodging/58000000/57710000/57709100/57709079/1cc7ae4d_edited_312c_y.jpg) ### Mi Casa Es Su Casa!!🏡 4 Bdrm home with pool 10/10 Excellent "We had a quick but enjoyable stay at this property. While we were there for less than 24 hours, what stood out was the host's quick response time. She was very quick to answer our questions and extremely helpful in giving us the information we needed. " [](https://expedia.ca/Orlando-Hotels-Mi-Casa-Es-Su-Casa-4-Bdrm-Home-With-Pool.h57709079.Hotel-Information) ## Hotels near other Sanford-Burnham Medical Research Institute attractions ### Austin-Tindall Regional Park Explore the great outdoors at Austin-Tindall Regional Park, a lovely green space in Kissimmee. Experience the entertainment choices or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635961253122) ### USTA National Campus Catch an event at USTA National Campus during your trip to Orlando. You can enjoy the restaurants while in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=982579279168655360) ### Eagle Creek Golf Club Enjoy a round of golf in Orlando at Eagle Creek Golf Club. Discover the top-notch restaurants and lively festivals in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6128540) ### David Leadbetter Golf Academy Explore the campus of David Leadbetter Golf Academy during your visit to Orlando. Stroll along the area's seaside, or simply savor its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654245) ### Kissimmee Bay Country Club Enjoy a round of golf in Kissimmee at Kissimmee Bay Country Club. Stroll along the seaside or experience the lively festivals in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6189596) ### Back to Nature Wildlife Refuge Take the family on an outing to Back to Nature Wildlife Refuge during your trip to Orlando. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561885904) ### North Shore Golf Club Enjoy a round of golf in Orlando at North Shore Golf Club. While in this family-friendly area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6189605) ### Split Oak Forest Mitigation Park Explore the great outdoors at Split Oak Forest Mitigation Park, a lovely green space in Orlando. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248622638917000) ## Frequently asked questions ### What's the area like around Sanford-Burnham Medical Research Institute? ### Where is the best place to stay close to Sanford-Burnham Medical Research Institute? ### How many hotels are there near Sanford-Burnham Medical Research Institute? ### If I need to cancel the hotel reservation for my stay near Sanford-Burnham Medical Research Institute, will I receive a refund? ### What can I see and do near Sanford-Burnham Medical Research Institute? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [5 Star Hotels in Lake Nona ](https://www.expedia.ca/5Star-Lake-Nona-Orlando-Hotels.s50-n6209488-0.Travel-Guide-Filter-Hotels) - [Airport North Hotels ](https://www.expedia.ca/Airport-North-Orlando-Hotels.0-n553248635976479214-0.Travel-Guide-Filter-Hotels) - [Hotels near Austin-Tindall Regional Park ](https://www.expedia.ca/Austin-Tindall-Regional-Park-Hotels.0-l553248635961253122-0.Travel-Guide-Filter-Hotels) - 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