Title: Hotels by Cruise Inn in San Luis Obispo | Expedia.ca [San Luis Obispo Travel Guide](https://expedia.ca/San-Luis-Obispo.dx6046822)[Hotels in San Luis Obispo](https://expedia.ca/San-Luis-Obispo-Hotels.d6046822.Travel-Guide-Hotels)[Vacation Rentals in San Luis Obispo](https://expedia.ca/San-Luis-Obispo-Vacation-Rentals.d6046822.Travel-Guide-VacationRentals)[Flights to San Luis Obispo](https://expedia.ca/Cheap-Flights-To-San-Luis-Obispo.d6046822.Travel-Guide-Flights)[Things to do in San Luis Obispo](https://expedia.ca/Things-To-Do-In-San-Luis-Obispo.d6046822.Travel-Guide-Activities)[San Luis Obispo Car Rentals](https://expedia.ca/Car-Rentals-In-San-Luis-Obispo.d6046822.Car-Rental-Guide)[San Luis Obispo Vacation Packages](https://expedia.ca/San-Luis-Obispo.d6046822.Destination-Travel-Guides) ![San Luis Obispo viewed from the Cerro Peak](https://images.trvl-media.com/place/6046822/18199fbf-6924-4e95-93c8-3a728f122148.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6046822/18199fbf-6924-4e95-93c8-3a728f122148.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 14 - Jan 15](https://www.expedia.ca/Hotel-Search?regionId=6046822&startDate=2026-01-14&endDate=2026-01-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 15 - Jan 16](https://www.expedia.ca/Hotel-Search?regionId=6046822&startDate=2026-01-15&endDate=2026-01-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6046822&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6046822&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSan-Luis-Obispo-Hotels-Cruise-Inn.0-0-d6046822--bCruiseInn.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSan-Luis-Obispo-Hotels-Cruise-Inn.0-0-d6046822--bCruiseInn.Travel-Guide-Filter-Hotels) ## Top San Luis Obispo Hotel Reviews ![La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/99fa5dc7_y.jpg) ### La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown 10/10 Excellent "Fresh remodeled hotel 5/5 stars Great breakfast, nice gym" [](https://expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information) ![Apple Farm](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41_y.jpg) ### Apple Farm 10/10 Excellent "Best hotel value for the price. I like my nice hotels and nothing else in SLO compares for proximity to town, walkable, great breakfast and clean and cozy rooms. My last room had a deck with patio lights! " [](https://expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Madonna Inn](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg) ### Madonna Inn 10/10 Excellent "Love the quirky theme rooms. Came for a wedding and it was gorgeous! Great restaurants and bar. Lovely grounds and pool." [](https://expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Avenue Inn Downtown San Luis Obispo](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/ec6a1c5f_y.jpg) ### Avenue Inn Downtown San Luis Obispo 10/10 Excellent "Clean!" [](https://expedia.ca/San-Luis-Obispo-Hotels-Avenue-Inn-Downtown-San-Luis-Obispo.h67485.Hotel-Information) ![Vagabond Inn San Luis Obispo](https://images.trvl-media.com/lodging/1000000/50000/42000/41941/488fecb6_y.jpg) ### Vagabond Inn San Luis Obispo 10/10 Excellent "Very clean. Pleasant staff. Very quiet weekend. Love the location. Dennys on site and right next to Madonna Inn" [](https://expedia.ca/San-Luis-Obispo-Hotels-Vagabond-Inn-San-Luis-Obispo.h41941.Hotel-Information) ![La Cuesta Inn, BW Signature Collection](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/f5b74a44_y.jpg) ### La Cuesta Inn, BW Signature Collection 10/10 Excellent "The staff was so nice!!! Super helpful and the hotel was clean. Overall great experience " [](https://expedia.ca/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information) ![Quality Suites Downtown San Luis Obispo](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291_y.jpg) ### Quality Suites Downtown San Luis Obispo 10/10 Excellent "Always a pleasure to stay at Quality Suites in SLO! Complimentary breakfast, happy hour, and bikes! Can't go wrong!! See you soon!" [](https://expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) ![SpringHill Suites by Marriott San Luis Obispo](https://images.trvl-media.com/lodging/112000000/111290000/111289700/111289681/78f1b4c8_y.jpg) ### SpringHill Suites by Marriott San Luis Obispo 10/10 Excellent "Clean room/lobby/gym. Very helpful staff." [](https://expedia.ca/San-Luis-Obispo-Hotels-SpringHill-Suites-By-Marriott-San-Luis-Obispo.h111289681.Hotel-Information) ![Hampton Inn & Suites San Luis Obispo](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857071/893b69cd_y.jpg) ### Hampton Inn & Suites San Luis Obispo 10/10 Excellent "The room was excellent very clean! We learned after noting our room was not made up that they only make up rooms after the 2nd night. Since we only had a two night stay our room was never cleaned. We did request towels. The mention of this may have been an over sight due to LARGE number of guests arriving the same night around the same time which filled up the hotel." [](https://expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-And-Suites-San-Luis-Obispo.h4857071.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - [Hilton Hotels in Avila Beach ](https://www.expedia.ca/Avila-Beach-Hotels-Hilton-Hotels.0-0-d11911--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Hotels near California Polytechnic State University ](https://www.expedia.ca/California-Polytechnic-State-University-Hotels.0-l6063425-0.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Cambria ](https://www.expedia.ca/Cambria-Hotels-Best-Western.0-0-d6194--bBestWestern.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Cambria ](https://www.expedia.ca/Cambria-Hotels-Marriott-Hotels-Resorts.0-0-d6194--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Hotels near Cerro San Luis Obispo ](https://www.expedia.ca/Cerro-San-Luis-Obispo-Hotels.0-l553248621532640001-0.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Creston ](https://www.expedia.ca/Creston-Hotels-Marriott-Hotels-Resorts.0-0-d3000427432--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - 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