San Luis Obispo Vacation Packages
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Your San Luis Obispo Vacation
Lock in a San Luis Obispo vacation package and prepare for a fabulous getaway. Renowned for its lively atmosphere and outdoorsy activities, there's tons to love about this lively city. Want to explore? Mission San Luis Obispo de Tolosa, California Polytechnic State University, San Luis Obispo and Fremont Theater are just three of the top-rated places to visit during your trip to San Luis Obispo. No matter your travel plans or budget, putting together the ultimate tailored San Luis Obispo vacation is a piece of cake with Expedia.
Top San Luis Obispo Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Where to stay in San Luis Obispo
Find the best San Luis Obispo areas and neighborhoods for the activities you enjoy most. Learn more about San Luis Obispo
Downtown San Luis Obispo
4 out of top 10 points of interest in this area
If you're spending some time in Downtown San Luis Obispo, Downtown SLO Farmers' Market and Mission San Luis Obispo de Tolosa are top sights worth seeing.
San Luis Obispo Hotel Deals
Madonna Inn
100 Madonna Road San Luis Obispo CA
The price is CA $329 per night from Apr 28 to Apr 29
CA $329
CA $421 total
Apr 28 - Apr 29
includes taxes & fees
9.2/10 Wonderful! (1,403 reviews)
Fun getaway
Reviewed on Mar 31, 2026
Quality Suites Downtown San Luis Obispo
1631 Monterey St San Luis Obispo CA
The price is CA $180 per night from Apr 21 to Apr 22
CA $180
CA $240 total
Apr 21 - Apr 22
includes taxes & fees
9.4/10 Exceptional! (1,381 reviews)
The outline of this hotel is super convenient when you have a lot of luggage, medical supplies and food. There’s a lot of room and very clean location. We will definitely stay again.
Reviewed on Mar 31, 2026
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
1845 Monterey St. San Luis Obispo CA
Fully refundableReserve now, pay when you stay
The price is CA $195 per night from Apr 21 to Apr 22
CA $195
CA $221 total
Apr 21 - Apr 22
includes taxes & fees
9/10 Wonderful! (1,913 reviews)
Our family enjoyed our stay here. The facility and amenities were very clean and had a modern flair. The kids especially enjoyed the daily breakfast. Close to downtown shops and restaurants and a great base to enjoy the neighboring towns like Morro Bay and Cambria. Highly recommend!
Reviewed on Apr 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in San Luis Obispo
Avila Hot Springs
4/5(1 review)
Explore the great outdoors at Avila Hot Springs and enjoy the beautiful sunsets during your trip to San Luis Obispo. Wander the beautiful beaches and seaside in this family-friendly area.
Mission San Luis Obispo de Tolosa
4.5/5(12 reviews)
Find out about the history of San Luis Obispo when you take a trip to Mission San Luis Obispo de Tolosa. Stroll along the area's beautiful beaches, or simply savor its top-notch restaurants.
Bubblegum Alley
4/5(3 reviews)
Colorful pieces of chewed gum, some of which have been turned into art pieces, decorate the walls of this narrow lane.
What to do in San Luis Obispo
San Luis Obispo: GPS-Guided Walking Audio Tour Via App
CA $12
per traveller
3-Hour Kayaking and Hiking in California’s Central Coast
CA $178
per adult
100% of travellers recommend
Santa Margarita: Zipline Adventure with 6 Different Ziplines
CA $163
per adult
Explore a world of travel with Expedia
- Hotels near California Polytechnic State University
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- Spa Hotels in Laguna
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- Arroyo Grande Vacations
- Avila Beach Vacations
- Avila Hot Springs
- Blacklake Golf Resort
- Bubblegum Alley
- Cambria Vacations
- Castoro Cellars Winery
- Cayucos State Beach
- Central Coast California Vacations
- Edna Vacations
- Fiscalini Ranch Preserve
- Mission San Luis Obispo de Tolosa
- Montaña de Oro State Park
- Moonstone Beach Park
- Morro Bay Vacations
- Morro Rock
- Morro Strand State Beach
- Paso Robles Wine Country Vacations
- Paso Robles Vacations
- Peachy Canyon Winery
- Peacock Cellars
- Pismo Beach Pier
- Pismo Beach Vacations
- Visit Downtown San Luis Obispo
- Visit Japantown
- Visit Lower Broad
- Visit Old Town Historic District
- San Miguel Vacations
- Santa Maria Valley Historical Society
- Santa Maria Vacations
- Tastes of the Valleys Wine Bar & Shop
- Templeton Vacations
- The Great American Melodrama & Vaudeville
- Vina Robles Winery and Amphitheater
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
