San Luis Obispo Vacation Packages
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Your San Luis Obispo Vacation
Lock in a San Luis Obispo vacation package and prepare for a fabulous getaway. Renowned for its lively atmosphere and outdoorsy activities, there's tons to love about this lively city. Want to explore? Mission San Luis Obispo de Tolosa, California Polytechnic State University, San Luis Obispo and Fremont Theater are just three of the top-rated places to visit during your trip to San Luis Obispo. No matter your travel plans or budget, putting together the ultimate tailored San Luis Obispo vacation is a piece of cake with Expedia.
Where to stay in San Luis Obispo
Find the best San Luis Obispo areas and neighborhoods for the activities you enjoy most. Learn more about San Luis Obispo
Downtown San Luis Obispo
4 out of top 10 points of interest in this area
If you're spending some time in Downtown San Luis Obispo, Downtown SLO Farmers' Market and Mission San Luis Obispo de Tolosa are top sights worth seeing.
San Luis Obispo Hotel Deals
Quality Suites Downtown San Luis Obispo
1631 Monterey St San Luis Obispo CA
Fully refundable
The price is CA $193 per night from May 26 to May 27
CA $193
CA $254 total
May 26 - May 27
includes taxes & fees
9.4/10 Exceptional! (1,409 reviews)
Very neat and clean. Breakfast was over the Top!
Reviewed on May 8, 2026
Madonna Inn
100 Madonna Road San Luis Obispo CA
Fully refundableReserve now, pay when you stay
The price is CA $200 per night from May 12 to May 13
CA $200
CA $273 total
May 12 - May 13
includes taxes & fees
9.2/10 Wonderful! (1,460 reviews)
Had a wonderful time
Reviewed on May 7, 2026
Vagabond Inn San Luis Obispo
210 Madonna Rd San Luis Obispo CA
Fully refundableReserve now, pay when you stay
The price is CA $83 per night from May 17 to May 18
CA $83
CA $111 total
May 17 - May 18
includes taxes & fees
8.4/10 Very Good! (1,295 reviews)
Room was great but what set this hotel apart from others even more was the care of the staff, primarily Acuoro. My family was arriving in pretty late and Acuoro worked with us to ensure our check in went smoothly. We will definitely stay here again.
Reviewed on May 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in San Luis Obispo
Avila Hot Springs
Explore the great outdoors at Avila Hot Springs and enjoy the beautiful sunsets during your trip to San Luis Obispo. Wander the beautiful beaches and seaside in this family-friendly area.
Mission San Luis Obispo de Tolosa
Find out about the history of San Luis Obispo when you take a trip to Mission San Luis Obispo de Tolosa. Stroll along the area's beautiful beaches, or simply savor its top-notch restaurants.
Bubblegum Alley
Colorful pieces of chewed gum, some of which have been turned into art pieces, decorate the walls of this narrow lane.
What to do in San Luis Obispo
San Luis Obispo: Santa Lucia Guided Nature Tour
CA $62
per adult
100% of travellers recommend
San Luis Obispo: GPS-Guided Walking Audio Tour Via App
CA $12
per traveller
3-Hour Kayaking and Hiking in California’s Central Coast
CA $179
per adult
100% of travellers recommend
Explore a world of travel with Expedia
- Hotels near California Polytechnic State University
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- Flights from San Luis Obispo County Regional
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- Arroyo Grande Vacations
- Avila Beach Vacations
- Avila Hot Springs
- Blacklake Golf Resort
- Bubblegum Alley
- Cambria Vacations
- Castoro Cellars Winery
- Cayucos State Beach
- Central Coast California Vacations
- Edna Vacations
- Fiscalini Ranch Preserve
- Mission San Luis Obispo de Tolosa
- Montaña de Oro State Park
- Moonstone Beach Park
- Morro Bay Vacations
- Morro Rock
- Morro Strand State Beach
- Paso Robles Wine Country Vacations
- Paso Robles Vacations
- Peachy Canyon Winery
- Peacock Cellars
- Pismo Beach Pier
- Pismo Beach Vacations
- Visit Downtown San Luis Obispo
- Visit Japantown
- Visit Lower Broad
- Visit Old Town Historic District
- San Miguel Vacations
- Santa Maria Valley Historical Society
- Santa Maria Vacations
- Tastes of the Valleys Wine Bar & Shop
- Templeton Vacations
- The Great American Melodrama & Vaudeville
- Vina Robles Winery and Amphitheater
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
