Title: Hotels by Independent in Panacea from CA $130 | Expedia.ca [Panacea Travel Guide](https://expedia.ca/Panacea.dx3000431554)[Hotels in Panacea](https://expedia.ca/Panacea-Hotels.d3000431554.Travel-Guide-Hotels)[Vacation Rentals in Panacea](https://expedia.ca/Panacea-Vacation-Rentals.d3000431554.Travel-Guide-VacationRentals)[Flights to Panacea](https://expedia.ca/Cheap-Flights-To-Panacea.d3000431554.Travel-Guide-Flights)[Panacea Car Rentals](https://expedia.ca/Car-Rentals-In-Panacea.d3000431554.Car-Rental-Guide)[Panacea Vacation Packages](https://expedia.ca/Panacea.d3000431554.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/a26f5e12f28d6a9b90f0a1284fcb27fc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Independent in Panacea from CA $130 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panacea Independent Hotels ![Reception](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/99ac7a1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/1d7bfd3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/83d33573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/0434072d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Wakulla Springs Crawfordville 9.4/10 Exceptional (1014) "We love staying here!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jackie [](https://www.expedia.ca/Tallahassee-Hotels-The-Lodge-At-Wakulla-Springs.h5411745.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/f9b0d233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/4ed5cee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/f15af7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/bef42b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wildwood Inn Crawfordville 8.6/10 Excellent (1001) "Raj is awesome! Room was clean, slept peacefully." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CHANDRA CA $173 CA $198 total includes taxes & fees Nov 18 - Nov 19 [](https://www.expedia.ca/Crawfordville-Hotels-Wildwood-Inn.h1532906.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cottage | Private kitchen](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/df64fc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio | Living area](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f2711545.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cottage | Terrace/patio](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/1434ed07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Panacea Motel Panacea 9.0/10 Wonderful (128) "Historical little place but clean and comfortable. Met the manager and she was a busy little gal and willing to help! A/C works great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fred [](https://www.expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/4470f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/a2c8b110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/c81957b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/9928e089.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Franklin Inn Carrabelle 7.8/10 Good (448) "Great staff- ease of checking in and out." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda CA $117 CA $130 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Carrabelle-Hotels-Franklin-Inn.h45034076.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/bb4da5df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/a49c599c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/fc5eefa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/678764d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St James Bay Golf & Pickleball Resort Carrabelle 9.0/10 Wonderful (364) "My wife and I stayed here while visiting family in Carrabelle, the Villa we stayed in as well the grounds in general were clean and very well kept up. The most memorable thing of the trip would be the staff, the restaurant manager and the server during the days we were there made us feel like we have known them for years. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kurt CA $223 CA $247 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Carrabelle-Hotels-St-James-Bay-Golf-Club.h23962755.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/f34571a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Condo, 2 Double Beds, River View | Private kitchen](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/e1c75ab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/b073fdcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/3b87d5f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Moorings Hotel and Marina Carrabelle 8.4/10 Very good (39) "Outstanding stay! Google Maps is a no go to find it. Right up beside the Carrabelle bridge on the Carrabelle side." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen S CA $194 CA $214 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Carrabelle-Hotels-The-Moorings-Hotel-And-Marina.h103241082.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/109000000/108410000/108408700/108408667/dad3a8f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/109000000/108410000/108408700/108408667/22c78ce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108410000/108408700/108408667/aa35b4e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/109000000/108410000/108408700/108408667/efa9cefa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pet friendly Kayak with the manatees Crawfordville 9.8/10 Exceptional (40) "Great and cozy! Will stay again if over that way!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole [](https://www.expedia.ca/Crawfordville-Hotels-Charming-3-Bedroom-House-With-AC-And-WiFi-In-Crawfordville.h108408667.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118720000/118717600/118717563/eedfea7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/119000000/118720000/118717600/118717563/w1290h853x0y0-0ec4e34e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/119000000/118720000/118717600/118717563/18002818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/119000000/118720000/118717600/118717563/b00aba0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property! Panacea 10/10 Exceptional (3) "This property was perfect. So fresh and awesome views. The best mattresses and pillows we have slept on in a long time. Very pet friendly. Great place to walk my dog. Wonderful kitchen. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jan C. [](https://www.expedia.ca/Panacea-Hotels-Spacious-4BR45BA-Bald-Point-Beach-Home-Perfect-For-Families-Groups.h118717563.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91690000/91683300/91683282/e9e83756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91690000/91683300/91683282/958eae7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91690000/91683300/91683282/26fee86d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, books](https://images.trvl-media.com/lodging/92000000/91690000/91683300/91683282/fc979db8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gulf Coast Getaway: 5BR Home with Private Dock – Keep Your Boat in the Water! Alligator Point 10/10 Exceptional (3) "Absolutely great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica M. CA $987 CA $1,750 total includes taxes & fees Nov 14 - Nov 15 [](https://www.expedia.ca/Panacea-Hotels-Waterfront-Luxury-Home-With-Dock.h91683282.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/34000000/33490000/33486800/33486730/f2e6bb56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/34000000/33490000/33486800/33486730/1438e705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/34000000/33490000/33486800/33486730/88f1d83a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33490000/33486800/33486730/702a1d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best deal at Alligator Point Alligator Point 9.8/10 Exceptional (130) "We enjoyed our stay, Excellent host and Excellent host. Property exceeded expectations. Loved the area the house, the fenced in front yard was excellent to walk our dogs. The pool table was a really nice thing to have to start the day and wind the day down." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Warren C. [](https://www.expedia.ca/Panacea-Hotels-Best-Deal-At-Alligator-Point.h33486730.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-19&endDate=2025-11-20®ionId=3000431554&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Hotels-Independent.0-0-d3000431554--bIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Hotels-Independent.0-0-d3000431554--bIndependent.Travel-Guide-Filter-Hotels) ## Top Panacea Hotel Reviews ![The Panacea Motel](//images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg) ### The Panacea Motel 10/10 Excellent "Staff was wonderful, room was clean and updated. It was everything we needed. " [](https://expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Best deal at Alligator Point](//images.trvl-media.com/lodging/34000000/33490000/33486800/33486730/f2e6bb56_y.jpg) ### Best deal at Alligator Point 10/10 Excellent "Very clean and comfortable. Every thing supplied for a nice relaxing stay. Wonderful view of the back bay and marshes. Not really a negative but the side fences only go to the water on one side in the back of property. Front yard is nicely fenced so no worries with the pet there. " [](https://expedia.ca/Panacea-Hotels-Best-Deal-At-Alligator-Point.h33486730.Hotel-Information) ![🏖️Beachfront🏖️ Forget your worries in this spacious and serene space ♡](//images.trvl-media.com/lodging/96000000/95740000/95733500/95733403/d7d85b44_y.jpg) ### 🏖️Beachfront🏖️ Forget your worries in this spacious and serene space ♡ 10/10 Excellent "Great location! Clean and well setup house. We had a great time!" [](https://expedia.ca/Panacea-Hotels-Beachfront-Forget-Your-Worries-In-This-Spacious-And-Serene-Space.h95733403.Hotel-Information) ![Beach Getaway Just Refreshed, Sleeps 8 <4 br> EV level 2 charging- views](//images.trvl-media.com/lodging/88000000/87140000/87136300/87136285/0a0672a1_y.jpg) ### Beach Getaway Just Refreshed, Sleeps 8 <4 br> EV level 2 charging- views 10/10 Excellent "Nice clean house on a quiet little street. Jessee is very communicative and friendly. Everything worked well including the EV charger, a rare item on the coast. " [](https://expedia.ca/Panacea-Hotels-Beach-Getaway-Just-Refreshed.h87136285.Hotel-Information) ![5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch](//images.trvl-media.com/lodging/75000000/74830000/74824400/74824331/169d337b_y.jpg) ### 5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch 10/10 Excellent "The property was absolutely wonderful!! The host communications was very responsive and timely. I would definitely recommend to anyone and would book again if ever in the area. My overall experience was a 5 out of 5!!! " [](https://expedia.ca/Panacea-Hotels-New-SEAcluded-Paradise-Updated-Steps-To-The-Beach-Oceanfront-Fish.h74824331.Hotel-Information) ![NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!](//images.trvl-media.com/lodging/119000000/118720000/118717600/118717563/eedfea7d_y.jpg) ### NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property! 10/10 Excellent "This property was perfect. So fresh and awesome views. The best mattresses and pillows we have slept on in a long time. Very pet friendly. Great place to walk my dog. Wonderful kitchen. " [](https://expedia.ca/Panacea-Hotels-Spacious-4BR45BA-Bald-Point-Beach-Home-Perfect-For-Families-Groups.h118717563.Hotel-Information) !["Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8 ](//images.trvl-media.com/lodging/64000000/63080000/63079600/63079590/63c77c39_y.jpg) ### "Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8 10/10 Excellent " CLose to beach" [](https://expedia.ca/Panacea-Hotels-Shifting-Sands-Private-Beach-Front-3-Bd.h63079590.Hotel-Information) ![Coastal Getaway on canal-steps to the beach](//images.trvl-media.com/lodging/79000000/78440000/78437300/78437246/22f909a1_y.jpg) ### Coastal Getaway on canal-steps to the beach 10/10 Excellent "My wife and I had a phenomenal stay here. Steven the host was very transparent and made things super easy. The house was clean and the beds and pillows were the first comfy ones we'd slept on during our roadtrip, which was much appreciated. The rear deck facing the canal was beautiful to sit at and just relax. And right down the road we saw the single most amazing sun rise we'd ever seen. This is an absolutely great place to stay if youre looking to get away and relax for a few days on the Gulf!" [](https://expedia.ca/Panacea-Hotels-Coastal-Getaway-On-Canal-Steps-To-The-Beach.h78437246.Hotel-Information) ![7 Bedroom Beach House with POOL!! Gulf Front and Bay Front](//images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/df15e6fc_y.jpg) ### 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front 10/10 Excellent "Love this house! Plenty of beds, great views and the house was stocked as well as I’ve ever seen in a rental property (I’m serious!!!). Thank you!" [](https://expedia.ca/Panacea-Hotels-7-Bedroom-Beach-House-With-POOL-Gulf-Front-And-Bay-Front.h19008298.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [2 Star Hotels in Carrabelle](https://www.expedia.ca/2Star-Carrabelle-Hotels.s20-0-d86458.Travel-Guide-Filter-Hotels) - [Farmstay in Alligator Point](https://www.expedia.ca/Alligator-Point-Agritourism.d553248635975849030-aaAgritourism.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Alligator Point](https://www.expedia.ca/Alligator-Point-Hotels-Beach-Hotel.0-0-d553248635975849030-tBeachHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Alligator Point](https://www.expedia.ca/Alligator-Point-Hotels-Cheap-Hotels.0-0-d553248635975849030-tCheapHotels.Travel-Guide-Filter-Hotels) - [Alligator Point Hotels](https://www.expedia.ca/Alligator-Point-Hotels.d553248635975849030.Travel-Guide-Hotels) - [Lodges in Alligator Point](https://www.expedia.ca/Alligator-Point-Lodges.d553248635975849030-aaLodges.Travel-Guide-Accommodation) - 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