Title: Book the Best Opelousas SPA Resorts from CA $321 - Spa Hotels in Opelousas, LA | Expedia.ca [Hotels in Opelousas](https://expedia.ca/Opelousas-Hotels.d9235.Travel-Guide-Hotels)[Vacation Rentals in Opelousas](https://expedia.ca/Opelousas-Vacation-Rentals.d9235.Travel-Guide-VacationRentals)[Opelousas Car Rentals](https://expedia.ca/Car-Rentals-In-Opelousas.d9235.Car-Rental-Guide)[Opelousas Vacation Packages](https://expedia.ca/Opelousas.d9235.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/6a609d96f4257cc1e6fa15e30688135e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Opelousas, LA from CA $321 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Opelousas Spa Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=9235&startDate=2025-10-15&endDate=2025-10-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=9235&startDate=2025-10-16&endDate=2025-10-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=9235&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=9235&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Opelousas Spa Hotels ![Couples treatment rooms, body treatments, hot stone massages](https://images.trvl-media.com/lodging/2000000/1760000/1753900/1753860/2687fdd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1760000/1753900/1753860/e0a0e6d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1760000/1753900/1753860/125c0f25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1760000/1753900/1753860/6ab93b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carriage House Hotel River Ranch 8.6/10 Excellent (210) "Wonderful stay with plenty of amenities, walking distance! " CA $279 CA $321 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Lafayette-Hotels-Carriage-House-Hotel.h1753860.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30®ionId=9235&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Opelousas Hotel Reviews ![Drury Inn & Suites Lafayette, LA](//images.trvl-media.com/lodging/2000000/1080000/1076500/1076487/6860c646_y.jpg) ### Drury Inn & Suites Lafayette, LA 10/10 Excellent "did not use hot tub..Breakfast was great!" [](https://expedia.ca/Lafayette-Hotels-Drury-Inn-Suites-Lafayette.h1076487.Hotel-Information) ![Hampton Inn & Suites Lafayette](//images.trvl-media.com/lodging/1000000/1000000/996100/996088/a95cd1cb_y.jpg) ### Hampton Inn & Suites Lafayette 10/10 Excellent "Our room was very comfortable. Ashley, the hostess of the breakfast room was awesome! She made us grits the first day and scrambled eggs the second day. Neither were on that days menu. Plenty of hot water for showers although the shower head was so far out my reach, I couldn't change the spray angle! Plenty of parking. We had a super weekend." [](https://expedia.ca/Lafayette-Hotels-Hampton-Inn-Suites-Lafayette.h996088.Hotel-Information) ![Holiday Inn Express & Suites Opelousas by IHG](//images.trvl-media.com/lodging/1000000/810000/808200/808193/2034d673_y.jpg) ### Holiday Inn Express & Suites Opelousas by IHG 10/10 Excellent "Great" [](https://expedia.ca/Lafayette-Hotels-Holiday-Inn-Hotel-Suites-Opelousas.h808193.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Opelousas? > Soothe the senses with some time in one of our wonderful spa hotels. Check out the historical sites and cafes in Opelousas—your day trip starts here. Take in the culture at the art galleries and museums during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your vacation. ### What's there to see and do in Opelousas? > Take in the sights and attractions that Opelousas offers with a visit to Evangeline Downs Racetrack & Casino, Rural African American Museum, and Fireman's Museum. If you have spare time during your trip, you might want to make a stop at Opelousas Historic District and Opelousas Public Library. ### What is a Opelousas spa hotel? > Spa hotels in Opelousas provide lodging and have an on-site spa which offers services including therapies as well as body treatments. Some also offer in-room treatments. 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