Title: Hotels by Red Roof Inn in Opelousas from CA $71 | Expedia.ca [Opelousas Travel Guide](https://expedia.ca/Opelousas.dx9235)[Hotels in Opelousas](https://expedia.ca/Opelousas-Hotels.d9235.Travel-Guide-Hotels)[Vacation Rentals in Opelousas](https://expedia.ca/Opelousas-Vacation-Rentals.d9235.Travel-Guide-VacationRentals)[Flights to Opelousas](https://expedia.ca/Cheap-Flights-To-Opelousas.d9235.Travel-Guide-Flights)[Opelousas Car Rentals](https://expedia.ca/Car-Rentals-In-Opelousas.d9235.Car-Rental-Guide)[Opelousas Vacation Packages](https://expedia.ca/Opelousas.d9235.Destination-Travel-Guides) ![The historic Dutch Romanesque Revival style Cathedral of Saint John the Evangelist or La Cathedrale St-Jean built in 1916 on Cathedral Street in downtown Lafayette, Louisiana, USA](https://images.trvl-media.com/place/9235/0930b9c0-a21c-4193-a87e-9efe9ae4e660.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Red Roof Inn in Opelousas from CA $71 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=9235&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=9235&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=9235&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=9235&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOpelousas-Hotels-Red-Roof-Inn.0-0-d9235--bRedRoofInn.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOpelousas-Hotels-Red-Roof-Inn.0-0-d9235--bRedRoofInn.Travel-Guide-Filter-Hotels) ## Top Opelousas Hotel Reviews ![La Quinta Inn & Suites by Wyndham Lafayette Oil Center](https://images.trvl-media.com/lodging/37000000/36490000/36485800/36485717/b11685e6_y.jpg) ### La Quinta Inn & Suites by Wyndham Lafayette Oil Center 10/10 Excellent "The room was clean and front desk was friendly " [](https://expedia.ca/Lafayette-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Lafayette-Oil-Center.h36485717.Hotel-Information) ![Sonesta ES Suites Lafayette Airport](https://images.trvl-media.com/lodging/1000000/130000/126800/126752/w3837h2560x3y0-447f1ce1_y.jpg) ### Sonesta ES Suites Lafayette Airport 10/10 Excellent "Nice, clean, friendly staff, coffee machine with cappuccino;)" [](https://expedia.ca/Lafayette-Hotels-Sonesta-ES-Suites-Lafayette-Airport.h126752.Hotel-Information) ![Hilton Garden Inn Lafayette/Cajundome](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340605/8bf3f3bb_y.jpg) ### Hilton Garden Inn Lafayette/Cajundome 10/10 Excellent "Stay was good. Staff was nice and helpful. " [](https://expedia.ca/Lafayette-Hotels-Hilton-Garden-Inn-LafayetteCajundome.h1340605.Hotel-Information) ![Holiday Inn Hotel & Suites Lafayette North by IHG](https://images.trvl-media.com/lodging/10000000/9730000/9727700/9727698/62a0b93e_y.jpg) ### Holiday Inn Hotel & Suites Lafayette North by IHG 10/10 Excellent "Room was great! Food was wonderful & the staff was super friendly. Highly recommend it!" [](https://expedia.ca/Lafayette-Hotels-Holiday-Inn-Hotel-Suites-Lafayette-North.h9727698.Hotel-Information) ![Microtel Inn & Suites by Wyndham Scott/Lafayette](https://images.trvl-media.com/lodging/1000000/290000/285000/284947/dd15070e_y.jpg) ### Microtel Inn & Suites by Wyndham Scott/Lafayette 10/10 Excellent "Room was clean, location was good and staff was pleasant." [](https://expedia.ca/Lafayette-Hotels-Microtel-Inn-Suites-By-Wyndham-ScottLafayette.h284947.Hotel-Information) ![DoubleTree by Hilton Hotel Lafayette](https://images.trvl-media.com/lodging/1000000/10000/3800/3724/37f8434e_y.jpg) ### DoubleTree by Hilton Hotel Lafayette 10/10 Excellent "Everyone and everything was exceptional. Really like clean air machine. My allergies were never that happy. Would definitely stay again and did I mention the warm cookies" [](https://expedia.ca/Lafayette-Hotels-DoubleTree-By-Hilton-Hotel-Lafayette.h3724.Hotel-Information) ![Comfort Suites Oil Center](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270802/a0479e17_y.jpg) ### Comfort Suites Oil Center 10/10 Excellent "Easily accessible, clean rooms and friendly staff" [](https://expedia.ca/Lafayette-Hotels-Comfort-Suites-Oil-Center.h4270802.Hotel-Information) ![Drury Inn & Suites Lafayette, LA](https://images.trvl-media.com/lodging/2000000/1080000/1076500/1076487/6860c646_y.jpg) ### Drury Inn & Suites Lafayette, LA 10/10 Excellent "The room is very clean , staff is beyond helpful, and breakfast buffet plus a snack buffet with a drink in the afternoon was exceptional for the price. I would recommend this hotel!" [](https://expedia.ca/Lafayette-Hotels-Drury-Inn-Suites-Lafayette.h1076487.Hotel-Information) ![WoodSpring Suites Lafayette](https://images.trvl-media.com/lodging/15000000/14670000/14663400/14663317/d2571989_y.jpg) ### WoodSpring Suites Lafayette 10/10 Excellent "Excellent " [](https://expedia.ca/Lafayette-Hotels-WoodSpring-Suites-Lafayette.h14663317.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Red Roof Inn Hotels in Alexandria ](https://www.expedia.ca/Alexandria-Hotels-Red-Roof-Inn.0-0-d1165--bRedRoofInn.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Amite ](https://www.expedia.ca/Amite-Hotels-La-Quinta-Inn-Suites.0-0-d6370--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Arnaudville Hotels ](https://www.expedia.ca/Arnaudville-Hotels.d553248634998706365.Travel-Guide-Hotels) - [Hyatt Hotels in Baton Rouge ](https://www.expedia.ca/Baton-Rouge-Hotels-Hyatt-Hotels.0-0-d603004--bHyattHotels.Travel-Guide-Filter-Hotels) - 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