Title: Mesopotamia Vacation Home Rentals from CA $58: Search Top Private Vacation Homes for Rent | Expedia.ca [Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides) ![Iguazu Falls featuring a cascade](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Mesopotamia ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/ab1ba3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Massages](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/bd533bb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Massages](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/35a3b74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/212e6606.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson Plaza La Ribera [](https://www.expedia.ca/Resistencia-Hotels-Howard-Johnson-Plaza-La-Ribera.h96445971.Hotel-Information) Resistencia 9.2/10 Wonderful (135 reviews) "Great location. Just across the street from a shopping mall. I had my bike on the truck bed and a safe parking was provided. The staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre [](https://www.expedia.ca/Resistencia-Hotels-Howard-Johnson-Plaza-La-Ribera.h96445971.Hotel-Information) ![Indoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/73000000/72560000/72556200/72556112/420f84f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/73000000/72560000/72556200/72556112/f948db46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72560000/72556200/72556112/a88f4722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/73000000/72560000/72556200/72556112/71674033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mercure Hotel Rosario [](https://www.expedia.ca/Rosario-Hotels-Mercure-Hotel-Rosario.h72556112.Hotel-Information) Rosario 8.0/10 Very good (17 reviews) "Excellent option " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diego CA $103 CA $103 total Mar 3 - Mar 4 [](https://www.expedia.ca/Rosario-Hotels-Mercure-Hotel-Rosario.h72556112.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/cfc48717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/03c0216a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/5622a56e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Corrientes Hotel [](https://www.expedia.ca/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) Corrientes 9.8/10 Exceptional (20 reviews) "Very nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $195 CA $195 total Feb 27 - Feb 28 [](https://www.expedia.ca/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/9eccf106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/c303d064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/ae215110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/e7b50f9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Puerto Norte Design Hotel [](https://www.expedia.ca/Rosario-Hotels-Puerto-Norte-Design-Hotel.h10633627.Hotel-Information) Rosario 9.2/10 Wonderful (146 reviews) "N/A" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diego [](https://www.expedia.ca/Rosario-Hotels-Puerto-Norte-Design-Hotel.h10633627.Hotel-Information) ![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/d7aa541d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/a0c96e7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/138c0f23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hathor Concordia [](https://www.expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) Concordia 8.6/10 Excellent (366 reviews) "AC did not work well, food was OK. Staff friendly. Good hotel for a stay on the road." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patrick [](https://www.expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/5a0bc70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/b05a90aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/8be36161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Triple Room, Park View](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/5ce32c6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Regina Lodge [](https://www.expedia.ca/Municipo-De-Itati-Hotels-La-Regina-Lodge.h120713176.Hotel-Information) Municipo de Itati CA $96 CA $96 total Feb 3 - Feb 4 [](https://www.expedia.ca/Municipo-De-Itati-Hotels-La-Regina-Lodge.h120713176.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/0e5b5ce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Pool View](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/c5ebe709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/9f96608b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/384ea822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mayim Hotel Termal & SPA [](https://www.expedia.ca/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) Concordia 9.2/10 Wonderful (7 reviews) "Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catalina CA $115 CA $115 total Mar 5 - Mar 6 [](https://www.expedia.ca/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/388c5726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c114ee3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c058d200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/ce5b95af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Alondra Casa De Huéspedes [](https://www.expedia.ca/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) Corrientes 9.2/10 Wonderful (68 reviews) "Todo excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Arturo Oscar CA $184 CA $184 total Feb 3 - Feb 4 [](https://www.expedia.ca/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/b3e275d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/0323f4ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room (VIP) | Jetted tub](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/ea0ac718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/216c6bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bungalows Mexico [](https://www.expedia.ca/Concepcion-Del-Uruguay-Hotels-Bungalows-Mexico.h15363214.Hotel-Information) Concepción del Uruguay 8.8/10 Excellent (12 reviews) "Local estava limpo, a cama é ótima, mas o banheiro a água n esquentava. O atendimento foi bom, são atenciosos. " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Eduardo CA $69 CA $69 total Mar 1 - Mar 2 [](https://www.expedia.ca/Concepcion-Del-Uruguay-Hotels-Bungalows-Mexico.h15363214.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/115000000/114600000/114592800/114592704/71c980b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathrobes, towels, toilet paper](https://images.trvl-media.com/lodging/115000000/114600000/114592800/114592704/1f6de405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Double Room, Garden View](https://images.trvl-media.com/lodging/115000000/114600000/114592800/114592704/6b9aa0cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/115000000/114600000/114592800/114592704/286a4e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nandereta Lodge [](https://www.expedia.ca/Colonia-Carlos-Pellegrini-Hotels-Nandereta-Lodge.h114592704.Hotel-Information) Colonia Carlos Pellegrini CA $273 CA $273 total Feb 12 - Feb 13 [](https://www.expedia.ca/Colonia-Carlos-Pellegrini-Hotels-Nandereta-Lodge.h114592704.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/6a6d02f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/f4e90853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/77b70130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, body treatments, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/96c06c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Maran Suites & Towers - Hotel & Spa [](https://www.expedia.ca/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information) Parana 9.0/10 Wonderful (32 reviews) "Great location and friendly, accommodating staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $124 CA $124 total Feb 18 - Feb 19 [](https://www.expedia.ca/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/69183496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/529e58c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/fb150aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/bbc0cb51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Estancia Iberá [](https://www.expedia.ca/Mercedes-Hotels-Estancia-Ibera.h111298221.Hotel-Information) Mercedes 10/10 Exceptional (1 review) "we had a wonderful experience the staff was very friendly and helpful and took us out on lots of activities and we saw an amazing amount of wildlife in a very short period of time. The place is very beautiful and tranquil. I would highly recommend it and give it five stars. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) orit CA $171 CA $171 total Feb 10 - Feb 11 [](https://www.expedia.ca/Mercedes-Hotels-Estancia-Ibera.h111298221.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/fb045420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Triple Suite + Trundle Bed (4 people)](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/4eedefaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/e9b4b524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/7aefeb63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donsuites Apart Hotel [](https://www.expedia.ca/Corrientes-Hotels-Donsuites-Apart-Hotel.h4947848.Hotel-Information) Corrientes 8.6/10 Excellent (106 reviews) "Loved this place, super clean, and the staff were very nice and helpful😍" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nora CA $83 CA $83 total Feb 3 - Feb 4 [](https://www.expedia.ca/Corrientes-Hotels-Donsuites-Apart-Hotel.h4947848.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/60e3bf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/750a674d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/7eec541e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Valle Termal Resort [](https://www.expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) Federacion 9.2/10 Wonderful (94 reviews) "Lamentablemente el lugar no refleja lo contratado por la plataforma. Cuando llegamos no tenían nuestras reservas, nos enviaron a una habitación con puerta de vidrio que no cerraba, arañas en la habitación, las sábanas viejas y manchadas, colchones vencidos y sin forro. Una experiencia espeluznante. " ![Costa Rica](https://a.travel-assets.com/egds/marks/flags/cr.svg) Pablo CA $66 CA $66 total Mar 4 - Mar 5 [](https://www.expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/5e4aef5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/a215cbf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rollaway beds, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/5b08b016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/cbc5acd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Posada Che Teindy [](https://www.expedia.ca/Colonia-Carlos-Pellegrini-Hotels-Posada-Che-Teindy.h38300196.Hotel-Information) Colonia Carlos Pellegrini CA $142 CA $142 total Feb 4 - Feb 5 [](https://www.expedia.ca/Colonia-Carlos-Pellegrini-Hotels-Posada-Che-Teindy.h38300196.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88090000/88087500/88087470/11027249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room](https://images.trvl-media.com/lodging/89000000/88090000/88087500/88087470/f479bf8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88090000/88087500/88087470/ba4b5c63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/89000000/88090000/88087500/88087470/e02a3f63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Complejo La Loma [](https://www.expedia.ca/Federacion-Hotels-Complejo-La-Loma.h88087470.Hotel-Information) Federacion 8.0/10 Very good (5 reviews) "Had a very good experience here. Hosts do not speak English, but were very patient with me as I used Google Translate to communicate. Woman at the desk was very kind. I had arrived late and was able to check in without issue. The suite is great - there is a full bathroom, bedroom and kitchen / dining area. There is a communal pool outside in the courtyard as well with lounge chairs. Breakfast was decent as well. Parking on site. I would stay here again for sure, but would be better for multiple... ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Logan [](https://www.expedia.ca/Federacion-Hotels-Complejo-La-Loma.h88087470.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/a0cc5957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/96c73453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, body treatments, hot stone massages, facials](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/ef76fc3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Costarenas Hotel & Spa [](https://www.expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) Colon 8.6/10 Excellent (60 reviews) "spectacular since we arrived the tstaff was wonderful and kind to us very helpful and nice answering all our questions, the hotel very comfortable!! the river view stunning" ![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg) Lisette CA $178 CA $178 total Mar 4 - Mar 5 [](https://www.expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/dbe6098c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/86b52c66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/3ea31922.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/7318806c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### O2 Hotel Gualeguaychú [](https://www.expedia.ca/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) Gualeguaychú 7.6/10 Good (70 reviews) "Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Esteban CA $58 CA $58 total Feb 3 - Feb 4 [](https://www.expedia.ca/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/98d1ea7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/fe749255.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/3843845d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/7d9efe4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Rio [](https://www.expedia.ca/Chajari-Hotels-Hotel-Rio.h36908421.Hotel-Information) Chajarí 8.8/10 Excellent (11 reviews) "Lindo hotel, moderno, limpio, buena atencion, sumaria opciones saladas en el desayuno, como huevos revueltos." ![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg) SANTIAGO CA $108 CA $108 total Mar 1 - Mar 2 [](https://www.expedia.ca/Chajari-Hotels-Hotel-Rio.h36908421.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/e9f90dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/29357765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/5a5e2fdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/5a9ad940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rio Arriba Suites Apartments y Resto [](https://www.expedia.ca/Bella-Vista-Hotels-Rio-Arriba-Suites-Apartments-Y-Resto.h15462513.Hotel-Information) Bella Vista 8.6/10 Excellent (4 reviews) "Pessoal da recepção excelente acolhimento. Hotel bonito, falta manutenção em certos lugares. Quarto ótimo, cama com colchão selado e barulho nos ares condicionados. Café da manhã deixa a desejar. Restaurante muito bonito. " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Anonymous traveller [](https://www.expedia.ca/Bella-Vista-Hotels-Rio-Arriba-Suites-Apartments-Y-Resto.h15462513.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-16&endDate=2026-02-17®ionId=6208836&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-05-03&d1=2026-05-03&endDate=2026-05-06&d2=2026-05-06&lodging=APART_HOTEL) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-05-03&d1=2026-05-03&endDate=2026-05-06&d2=2026-05-06&lodging=APARTMENT) Cabins [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-05-03&d1=2026-05-03&endDate=2026-05-06&d2=2026-05-06&lodging=CABIN) Condos [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-05-03&d1=2026-05-03&endDate=2026-05-06&d2=2026-05-06&lodging=CONDO) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-05-03&d1=2026-05-03&endDate=2026-05-06&d2=2026-05-06&lodging=COTTAGE) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-05-03&d1=2026-05-03&endDate=2026-05-06&d2=2026-05-06&lodging=VACATION_HOME) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Private-Vacation-Homes.d6208836-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Private-Vacation-Homes.d6208836-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Mesopotamia Hotel Reviews ![Holiday Inn Rosario by IHG](https://images.trvl-media.com/lodging/1000000/580000/570400/570357/61653463_y.jpg) ### Holiday Inn Rosario by IHG 10/10 Excellent "Clean rooms, felt like I was in the USA" [](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Rosario.h570357.Hotel-Information) ![Marriott Corrientes Hotel](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686_y.jpg) ### Marriott Corrientes Hotel 10/10 Excellent "Excelente " [](https://expedia.ca/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) ![Intersur Colon](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56_y.jpg) ### Intersur Colon 6/10 Okay "Is ok " [](https://expedia.ca/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information) ![Howard Johnson Plaza La Ribera](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/c44de299_y.jpg) ### Howard Johnson Plaza La Ribera 10/10 Excellent "Great location. Just across the street from a shopping mall. I had my bike on the truck bed and a safe parking was provided. The staff was very friendly. " [](https://expedia.ca/Resistencia-Hotels-Howard-Johnson-Plaza-La-Ribera.h96445971.Hotel-Information) ![Holiday Inn Express Rosario by IHG](https://images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg) ### Holiday Inn Express Rosario by IHG 10/10 Excellent "Clean room. Very nice staffing. Very good breakfast " [](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information) ![Hathor Concordia](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg) ### Hathor Concordia 10/10 Excellent "The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional"." [](https://expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![Club Valle Termal Resort](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710_y.jpg) ### Club Valle Termal Resort 10/10 Excellent "La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto." [](https://expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![Costarenas Hotel & Spa](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01_y.jpg) ### Costarenas Hotel & Spa 2/10 Terrible "Short Version See pictures for detailed information) - Rooms and bathrooms are small, shower already tight spaced with doors that don’t close properly. - By day 3, construction noise and chemicals smells from remodeling work became a big issue. - Receptionist did not offer solutions and lied about remodeling hours. Felt uncomfortable when asked for manager’s name, and refused to give any other information. - Same receptionist reached out later to apologize and acknowledged we should have not been placed in those rooms to begin with. Offered to move us to “upgraded” rooms. - “Upgraded” rooms were even worse. One of the rooms was directly under the ones being remodeled and worked on. Noise began at 8 AM - The other two rooms did not have a functioning air conditioner. Staff gave poor excuse and just said to open windows. There’s tons of noise far into the night from motor bikes and people playing music right across the hotel. - Hotel breakfast was motel level at best. You get eggs swimming in water and some cut up ham. Toasters barely worked, and when staff was asked for replacement they appeared completely clueless. - The spa experience was good when it came to the massage. However “quiet” policy is not enforced and hearing toilets go off right next to the spa area don’t help with the experience. - Check out was the final straw. Desk staff was rude and dismissive of concerns, stating that the room “upgrade” was sufficient compensation for the troubles. " [](https://expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) ![Hotel y Spa Termas del Este](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/459986e2_y.jpg) ### Hotel y Spa Termas del Este 8/10 Good "good for a 1 night stay" [](https://expedia.ca/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) ## Find out more about Mesopotamia ## Mesopotamia Vacation Homes information | Number of reviews | 1,133 | | ----------------- | ----------------- | | Accommodation | 83 Vacation Homes | | Lowest Price | CA $58 | | Highest Price | CA $273 | ## Explore a world of travel with Expedia - More ways to book - [Book Vacation Homes in Mesopotamia on Expedia.com.ar ](https://www.expedia.com.ar/Mesopotamia-Casas-De-Vacaciones-Privadas.d6208836-aaCasasDeVacacionesPrivadas.Guia-Viajes-Alojamiento)