Title: Book The Best Hotels in Mesopotamia for 2026 from CA $48 - Fully Refundable Options - Expedia.ca [Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides) ![Iguazu Falls showing a waterfall](https://images.trvl-media.com/place/6171898/03a05306-ef99-4659-ab63-b0ba88517045.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Mesopotamia from CA $48 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mesopotamia Spa [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=APART_HOTEL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=APARTMENT) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=PETS) ## Check prices for these dates Tonight [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesopotamia hotels ![Living area](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/a1bc361e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/19d6d5c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/187f4e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/1bb2bfd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa del Árbol [](https://www.expedia.ca/Concepcion-Del-Uruguay-Hotels-Casa-Del-Arbol.h36653372.Hotel-Information) Concepción del Uruguay 8.4/10 Very good (8) "La primera vez que venga a Concepcion del Uruguay, quiero alquilar en" la casa del arbol" Me sentí muy bienvenida y en buena compañía, los anfitriones son maravillosos " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Olga Beatriz CA $53 CA $53 total Dec 15 - Dec 16 [](https://www.expedia.ca/Concepcion-Del-Uruguay-Hotels-Casa-Del-Arbol.h36653372.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/0e5b5ce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/8d2994c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Pool View](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/c5ebe709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/384ea822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mayim Hotel Termal & SPA [](https://www.expedia.ca/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) Concordia 8.8/10 Excellent (5) "Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catalina CA $124 CA $124 total Dec 16 - Dec 17 [](https://www.expedia.ca/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/cfc48717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/03c0216a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/5622a56e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Corrientes Hotel [](https://www.expedia.ca/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) Corrientes 9.4/10 Exceptional (6) "Very nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $172 CA $172 total Dec 26 - Dec 27 [](https://www.expedia.ca/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/38000000/37850000/37849700/37849633/a2d4e241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/38000000/37850000/37849700/37849633/07bb3b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37850000/37849700/37849633/f200b026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/38000000/37850000/37849700/37849633/665bd10d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Crespo [](https://www.expedia.ca/Crespo-Hotels-Hotel-Crespo.h37849633.Hotel-Information) Crespo 10/10 Exceptional (1) [](https://www.expedia.ca/Crespo-Hotels-Hotel-Crespo.h37849633.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/98d1ea7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/3843845d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/7d9efe4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/a62b286b_edited_cdf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Rio [](https://www.expedia.ca/Chajari-Hotels-Hotel-Rio.h36908421.Hotel-Information) Chajarí 8.8/10 Excellent (11) "Lindo hotel, moderno, limpio, buena atencion, sumaria opciones saladas en el desayuno, como huevos revueltos." ![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg) SANTIAGO CA $107 CA $107 total Dec 15 - Dec 16 [](https://www.expedia.ca/Chajari-Hotels-Hotel-Rio.h36908421.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/69183496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/bbc0cb51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/fb150aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 3 Bedrooms, Balcony | Living area](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/75cc2c4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Estancia Iberá [](https://www.expedia.ca/Mercedes-Hotels-Estancia-Ibera.h111298221.Hotel-Information) Mercedes 10/10 Exceptional (1) "we had a wonderful experience the staff was very friendly and helpful and took us out on lots of activities and we saw an amazing amount of wildlife in a very short period of time. The place is very beautiful and tranquil. I would highly recommend it and give it five stars. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) orit CA $175 CA $175 total Jan 14 - Jan 15, 2026 [](https://www.expedia.ca/Mercedes-Hotels-Estancia-Ibera.h111298221.Hotel-Information) ![Classic Apartment, 1 Bedroom, Private Bathroom | Terrace/patio](https://images.trvl-media.com/lodging/110000000/109940000/109932400/109932326/9553db63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/110000000/109940000/109932400/109932326/8af23b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/110000000/109940000/109932400/109932326/787922a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/110000000/109940000/109932400/109932326/d6919071.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Don Pedro Apart Hotel [](https://www.expedia.ca/Federacion-Hotels-Don-Pedro-Apart-Hotel.h109932326.Hotel-Information) Federacion 10/10 Exceptional (1) "Estuvo muy bien, la atención fue muy buena. " ![Costa Rica](https://a.travel-assets.com/egds/marks/flags/cr.svg) Marianela CA $42 CA $42 total Dec 15 - Dec 16 [](https://www.expedia.ca/Federacion-Hotels-Don-Pedro-Apart-Hotel.h109932326.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/b3e275d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/0323f4ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room (VIP) | Jetted tub](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/ea0ac718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/216c6bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bungalows Mexico [](https://www.expedia.ca/Concepcion-Del-Uruguay-Hotels-Bungalows-Mexico.h15363214.Hotel-Information) Concepción del Uruguay 8.8/10 Excellent (12) "Local estava limpo, a cama é ótima, mas o banheiro a água n esquentava. O atendimento foi bom, são atenciosos. " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Eduardo CA $82 CA $82 total Dec 15 - Dec 16 [](https://www.expedia.ca/Concepcion-Del-Uruguay-Hotels-Bungalows-Mexico.h15363214.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/60e3bf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/7876fff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/7eec541e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Valle Termal Resort [](https://www.expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) Federacion 9.2/10 Wonderful (94) "Lamentablemente el lugar no refleja lo contratado por la plataforma. Cuando llegamos no tenían nuestras reservas, nos enviaron a una habitación con puerta de vidrio que no cerraba, arañas en la habitación, las sábanas viejas y manchadas, colchones vencidos y sin forro. Una experiencia espeluznante. " ![Costa Rica](https://a.travel-assets.com/egds/marks/flags/cr.svg) Pablo CA $66 CA $66 total Dec 15 - Dec 16 [](https://www.expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/106000000/105130000/105127300/105127292/19db5632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105130000/105127300/105127292/2e4f3329.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/106000000/105130000/105127300/105127292/53fe20bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105130000/105127300/105127292/0be399b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Estancia La Violeta [](https://www.expedia.ca/Chajari-Hotels-Estancia-La-Violeta.h105127292.Hotel-Information) Chajarí 8.8/10 Excellent (3) "Best place to spend a few days resting espero under by natural beauty and Argentinian estancia history. The staff is amazing. We will be back" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Orestes CA $218 CA $218 total Dec 16 - Dec 17 [](https://www.expedia.ca/Chajari-Hotels-Estancia-La-Violeta.h105127292.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/a0cc5957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/96c73453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, body treatments, hot stone massages, facials](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/ef76fc3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/c45620e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Costarenas Hotel & Spa [](https://www.expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) Colon 8.6/10 Excellent (58) "spectacular since we arrived the tstaff was wonderful and kind to us very helpful and nice answering all our questions, the hotel very comfortable!! the river view stunning" ![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg) Lisette [](https://www.expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/115000000/114350000/114341100/114341005/49ebfae0_edited_0267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114350000/114341100/114341005/92208950.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114350000/114341100/114341005/ebb3bbdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Triple Room, Courtyard View](https://images.trvl-media.com/lodging/115000000/114350000/114341100/114341005/5db6bc97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### COSTA NORTE HOSTERIA [](https://www.expedia.ca/Colon-Hotels-COSTA-NORTE-HOSTERIA.h114341005.Hotel-Information) Colón 8.0/10 Very good (1) "O quarto e banheiro estavam impecaveis. A equipe de recepção foi muito reativa, quiseram me cobrar o quarto a pesar que mostrei o recibo de pagamento no site da Hoteis.com, e também achamos que o horario do cafe da manhã é muito tarde (a partir das 8.30), como a nossa partida foi mais cedo, pela nossa insistencia nos serviram apenas um cafe mais simples." ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Antonio CA $74 CA $74 total Dec 21 - Dec 22 [](https://www.expedia.ca/Colon-Hotels-COSTA-NORTE-HOSTERIA.h114341005.Hotel-Information) ![Executive Apartment | Private kitchen](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/6427ef82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City Apartment | Living area](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/f34322b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Duplex](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/960ad1f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/aa85566a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Agustín 1 Apart [](https://www.expedia.ca/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information) Parana 9.0/10 Wonderful (4) "Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável." ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Jose rodrigo kallas CA $74 CA $74 total Dec 15 - Dec 16 [](https://www.expedia.ca/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/e90b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/5cbe2a6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/dd41bc20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/a9efae27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Spa Termas del Este [](https://www.expedia.ca/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) Federacion 8.4/10 Very good (12) "good for a 1 night stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Chase [](https://www.expedia.ca/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) ![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/d7aa541d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/a0c96e7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cf8e0206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hathor Concordia [](https://www.expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) Concordia 8.6/10 Excellent (355) "The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional"." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edwin [](https://www.expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/fb045420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Triple Suite + Trundle Bed (4 people)](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/4eedefaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/7aefeb63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/e9b4b524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donsuites Apart Hotel [](https://www.expedia.ca/Corrientes-Hotels-Donsuites-Apart-Hotel.h4947848.Hotel-Information) Corrientes 8.6/10 Excellent (105) "Loved this place, super clean, and the staff were very nice and helpful😍" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nora CA $97 CA $97 total Dec 16 - Dec 17 [](https://www.expedia.ca/Corrientes-Hotels-Donsuites-Apart-Hotel.h4947848.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/388c5726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c058d200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c114ee3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/ff681a63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Alondra Casa De Huéspedes [](https://www.expedia.ca/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) Corrientes 9.2/10 Wonderful (65) "De lo mejor ! Excelente atención del hotel y restaurante!" ![Costa Rica](https://a.travel-assets.com/egds/marks/flags/cr.svg) Maria del Carmen [](https://www.expedia.ca/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/e9f90dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/5a9ad940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/5a5e2fdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/29357765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rio Arriba Suites Apartments y Resto [](https://www.expedia.ca/Bella-Vista-Hotels-Rio-Arriba-Suites-Apartments-Y-Resto.h15462513.Hotel-Information) Bella Vista 8.6/10 Excellent (4) "Pessoal da recepção excelente acolhimento. Hotel bonito, falta manutenção em certos lugares. Quarto ótimo, cama com colchão selado e barulho nos ares condicionados. Café da manhã deixa a desejar. Restaurante muito bonito. " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Anonymous traveller [](https://www.expedia.ca/Bella-Vista-Hotels-Rio-Arriba-Suites-Apartments-Y-Resto.h15462513.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/dbe6098c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/3ea31922.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/7318806c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### O2 Hotel Gualeguaychú [](https://www.expedia.ca/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) Gualeguaychú 7.8/10 Good (66) "Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Esteban CA $48 CA $48 total Dec 15 - Dec 16 [](https://www.expedia.ca/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![Food and drink](https://images.trvl-media.com/lodging/5000000/4310000/4304600/4304547/48f28ed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/5000000/4310000/4304600/4304547/308b5970.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4310000/4304600/4304547/69e2ac6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium House, Multiple Beds](https://images.trvl-media.com/lodging/5000000/4310000/4304600/4304547/29539b08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rincón del Socorro [](https://www.expedia.ca/Colonia-Carlos-Pellegrini-Hotels-Rincon-Del-Socorro.h4304547.Hotel-Information) Mercedes 10/10 Exceptional (6) "People could not be nicer. It is a jewel that needs to be protected and cherished" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller CA $826 CA $826 total Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Colonia-Carlos-Pellegrini-Hotels-Rincon-Del-Socorro.h4304547.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29®ionId=6208836&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Mesopotamia Showing deals for:**Dec 26 - Dec 28** ### Image gallery for Hathor Concordia ![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hathor Concordia Concordia **8.6/10**Excellent (355 reviews) 25% off CA $120 CA $240 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=4668235&adults=2) ### Image gallery for Mayim Hotel Termal & SPA ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/0e5b5ce6.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Mayim Hotel Termal & SPA Concordia **8.8/10**Excellent (5 reviews) 12% off CA $163 CA $327 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=111541690&adults=2) ### Image gallery for Maran Suites & Towers - Hotel & Spa ![Front of property](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/6a6d02f8.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Maran Suites & Towers - Hotel & Spa Parana **9.2/10**Wonderful (31 reviews) 19% off CA $146 CA $293 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=36800965&adults=2) ### Image gallery for Intersur Colon ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Intersur Colon Colon **10/10**Exceptional (2 reviews) Member Price available CA $176 CA $353 total [Sign in for Member Price ](https://www.expedia.ca/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-12-26%26endDate%3D2025-12-28%26selected%3D114109755%26adults%3D2) [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=114109755&adults=2) ### Image gallery for COSTA NORTE HOSTERIA ![Free daily continental breakfast](https://images.trvl-media.com/lodging/115000000/114350000/114341100/114341005/49ebfae0_edited_0267.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### COSTA NORTE HOSTERIA Colon **8.0/10**Very good (1 review) 10% off CA $77 CA $153 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=114341005&adults=2) ### Image gallery for Agustín 1 Apart ![Executive Apartment | Private kitchen](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/6427ef82.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Agustín 1 Apart Parana **9.0/10**Wonderful (4 reviews) 10% off CA $124 CA $248 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=99269311&adults=2) ### Image gallery for La Alondra Casa De Huéspedes ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/388c5726.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### La Alondra Casa De Huéspedes Corrientes **9.2/10**Wonderful (65 reviews) 20% off CA $190 CA $381 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=2803582&adults=2) ### Image gallery for Don Pedro Apart Hotel ![Classic Apartment, 1 Bedroom, Private Bathroom | Terrace/patio](https://images.trvl-media.com/lodging/110000000/109940000/109932400/109932326/9553db63.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Don Pedro Apart Hotel Federacion **10/10**Exceptional (1 review) 11% off CA $42 CA $85 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=109932326&adults=2) ### Image gallery for Verde y Sol en la Colonia ![Exterior](https://images.trvl-media.com/lodging/38000000/37270000/37265200/37265185/ea8d3387.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Verde y Sol en la Colonia Concepción del Uruguay **9.0/10**Wonderful (2 reviews) 10% off CA $102 CA $204 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=37265185&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6208836.Travel-Guide-Hotels) ## Learn more about Mesopotamia The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration. [See all hotels in Mesopotamia](https://www.expedia.ca/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29&adults=2®ionId=6208836) ![Mesopotamia showing a river or creek and forests](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ### Stay near popular Mesopotamia attractions [](https://expedia.ca/Victoria-Beach-Hotels.0-l6250473-0.Travel-Guide-Filter-Hotels) #### Victoria Beach If a restful vacation is part of your travel plans, Victoria Beach might be the perfect place to seek out during your trip to Victoria. Make some time to visit the monuments while you're in the area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6250473) ## More cheap stays in Mesopotamia ![O2 Hotel Gualeguaychú](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### O2 Hotel Gualeguaychú 115 3 de Febrero Gualeguaychú Entre Ríos CA $48 CA $48 total Dec 15 - Dec 16 7.6/10 Good! (66 reviews) [](https://expedia.ca/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![ibis Puerto General San Martin](https://images.trvl-media.com/lodging/116000000/115200000/115198900/115198842/44d34201_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### ibis Puerto General San Martin El Espinillo Puerto General San Martín San Lorenzo CA $65 CA $65 total Dec 18 - Dec 19 [](https://expedia.ca/Puerto-General-San-Martin-Hotels-Ibis-Puerto-San-Martin.h115198842.Hotel-Information) ![Bungalows Mexico](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/cbf4c2c0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Bungalows Mexico Carlos Granillo Posse N 197 Concepción del Uruguay Entre Rios CA $82 CA $82 total Dec 15 - Dec 16 [](https://expedia.ca/Concepcion-Del-Uruguay-Hotels-Bungalows-Mexico.h15363214.Hotel-Information) ![Apart Club San Pedro](https://images.trvl-media.com/lodging/97000000/96050000/96040300/96040239/5d1d5b89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Apart Club San Pedro Lucio Mansilla 7300 San Pedro Buenos Aires Province [Get rates](https://expedia.ca/Hotel-Search?startDate=28%2F12%2F2025&endDate=29%2F12%2F2025&selected=96040239&PinnedHotelID=96040239&HadPinnedHotel=true®ionId=6208836) [](https://expedia.ca/San-Pedro-Hotels-San-Pedro.h96040239.Hotel-Information) ![Apart Hotel Las Violetas](https://images.trvl-media.com/lodging/92000000/91280000/91272000/91271956/0b3e9773_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Apart Hotel Las Violetas Barrio del Lago Candelaria Misiones [Get rates](https://expedia.ca/Hotel-Search?startDate=28%2F12%2F2025&endDate=29%2F12%2F2025&selected=91271956&PinnedHotelID=91271956&HadPinnedHotel=true®ionId=6208836) [](https://expedia.ca/Candelaria-Hotels-Apart-Hotel-Las-Violetas.h91271956.Hotel-Information) ![Hostal Santa Fe de la Veracruz ](https://images.trvl-media.com/lodging/5000000/4410000/4404900/4404816/bd301f09_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hostal Santa Fe de la Veracruz San Martin 2954 Santa Fe Santa Fe [Get rates](https://expedia.ca/Hotel-Search?startDate=28%2F12%2F2025&endDate=29%2F12%2F2025&selected=4404816&PinnedHotelID=4404816&HadPinnedHotel=true®ionId=6208836) [](https://expedia.ca/Santa-Fe-Hotels-Hostal-Santa-Fe-De-La-Veracruz.h4404816.Hotel-Information) ## Hotels in Mesopotamia with star-rating ![5 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25559/c6e0103a_z.jpg) 5 Star Hotels 1 properties [](https://expedia.ca/5Star-Mesopotamia-Hotels.s50-0-d6208836.Travel-Guide-Filter-Hotels) ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 17 properties [](https://expedia.ca/4Star-Mesopotamia-Hotels.s40-0-d6208836.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 157 properties [](https://expedia.ca/3Star-Mesopotamia-Hotels.s30-0-d6208836.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 140 properties [](https://expedia.ca/2Star-Mesopotamia-Hotels.s20-0-d6208836.Travel-Guide-Filter-Hotels) ## Find out more about Mesopotamia ### Top reasons to visit Mesopotamia - **Scenic National Parks:** Explore stunning national parks with breathtaking mountain views and lush landscapes, perfect for nature lovers. - **Outdoor Adventures:** Engage in exciting activities like hiking, birdwatching, and water parks, catering to both thrill-seekers and families. - **Charming Neighbourhoods:** Stroll through romantic neighbourhoods like Bahcamatiate and Midyat, offering a delightful atmosphere. - **Family-Friendly Activities:** Enjoy a variety of attractions designed for family vacations that ensure fun for all ages. - **Comfortable Accommodations:** Stay in diverse hotel options, from cozy retreats to luxurious facilities, ensuring a memorable experience. ### Find great hotels near Mesopotamia Discover a variety of hotel accommodations in Mesopotamia, Argentina, designed for families seeking unforgettable vacations. From cozy retreats to top-notch star-rated facilities, you’ll find options that suit every traveller's needs. Whether you're looking for the best hotels or a tranquil stay at the Calma Hotel, Mesopotamia offers a welcoming atmosphere and essential amenities to make your stay memorable. - **[El Tránsito Hotel Boutique: ](https://www.expedia.ca/Concepcion-Hotels-Hotel-Boutique-El-Transito.h41507004.Hotel-Information)** Nestled 29.0km from Mesopotamia, El Tránsito Hotel Boutique offers a charming family-friendly atmosphere perfect for a memorable vacation. This 3.5-star hotel is designed with families in mind, featuring an Arcade Game Room, a children's pool, and complimentary cribs. Guests appreciate the inviting ambiance, attentive service, and amenities tailored for kids, ensuring a delightful stay for both parents and children. Embrace the warmth of Argentinian hospitality while enjoying a peaceful retreat at this lovely boutique hotel. ### Where to stay near Mesopotamia Mesopotamia, Argentina, offers an exciting blend of adventure and relaxation for every family. Discover the breathtaking mountain views while exploring the scenic trails and lush landscapes nearby. The charming neighborhoods, like Bahcamatiate and Midyat, provide a romantic backdrop for leisurely strolls. Whether you're hiking or enjoying outdoor activities, the region promises an unforgettable experience that combines natural beauty with family-friendly fun. - **[Mercedes: ](https://www.expedia.ca/Mercedes-Hotels.d6338887.Travel-Guide-Hotels)** Nestled 49.9km from Mesopotamia, Mercedes is a vibrant city that offers a delightful mix of outdoor adventures and family-friendly experiences. Visitors are drawn to its national state park, water park, and theme park, making it an ideal destination for thrill-seekers and nature lovers alike. The city sees a surge in tourist activity during July and the festive season from December to January, but it's a year-round destination for those seeking adventure. Whether you're swinging a club at a local golf course or splashing around at the water park, Mercedes promises an exhilarating getaway. - **[Concepción: ](https://www.expedia.ca/Concepcion-Hotels.d553248635924012399.Travel-Guide-Hotels)** Located 35.4km from Mesopotamia, Concepción is a picturesque city perfect for outdoor enthusiasts and those seeking scenic beauty. The city's allure peaks in April, July, and September, attracting visitors keen on exploring its national state park and surrounding natural parks. With ample opportunities for hiking and sightseeing, Concepción invites you to immerse yourself in its stunning landscapes. The relatively stable visitor numbers throughout the year mean you can enjoy a quieter experience while still indulging in its natural charm. - **Uguay:** Just 27.4km from Mesopotamia, Uguay is a quaint village that embodies the essence of tranquil rural life. Known for its seasonal visitor influx, peaking in January, March, and November, Uguay is a haven for nature lovers. The nearby natural parks provide a serene backdrop for leisurely hikes and picnics amidst stunning landscapes. If you’re looking for a slow-paced escape from the hustle and bustle of city life, Uguay offers a peaceful retreat that celebrates the beauty of the great outdoors. ### Things to do in Mesopotamia Mesopotamia, Argentina, offers a variety of activities perfect for family and adventure vacations. Visitors can enjoy exciting attractions such as water parks, birdwatching, and scenic hiking trails. This diverse region ensures a memorable experience for tourists seeking both relaxation and outdoor fun. **Shopping** In Mesopotamia, you can explore shopping at the Shopping del Sol, featuring popular brands and local boutiques. For a more traditional experience, visit the Mercado Municipal, where you’ll find unique handicrafts and delicious regional foods, perfect for gifts and souvenirs. **Recreation** Experience a tranquil stay at Termas de Río Hondo, where you can indulge in natural thermal baths and rejuvenating spa treatments. For recreation, explore the lush landscapes on horseback or enjoy leisurely walks along the scenic riverside, immersing yourself in the serene beauty of Mesopotamia. **Adventure** Explore the stunning Ibera Wetlands, home to diverse wildlife, by canoe or kayak. Experience thrilling hikes through lush landscapes at Quebrada de Humahuaca, where you can marvel at vibrant rock formations and learn about the region's rich cultural heritage. **Nightlife** The nightlife in Mesopotamia, Argentina, is vibrant and diverse. Enjoy a lively evening at local bars like El Club de la Cerveza for craft brews, or dance the night away at La Fiesta, where live music creates an electrifying atmosphere. Experience the unique culture and warm hospitality of the region. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Mesopotamia When planning your trip to Mesopotamia, Argentina, consider visiting during the off-peak months for lower prices, avoiding July, August, and December. Book accommodations about a month in advance or check Expedia's last-minute deals for savings. Tuesdays are the best days for cheaper stays, while Mondays tend to be pricier. Use Expedia’s search tools to filter for budget-friendly and eco-certified options, and consider bundling your hotel, flights, and activities for additional discounts. Look out for free activities in the area to maximize your enjoyment without breaking the bank. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Mesopotamia are , where the prices are slightly lower. This is in comparison to July to August and December, where prices are slightly higher. - **The best time to book a hotel:** The cheapest time to book a hotel around Mesopotamia is usually 1 month out from when you are planning to stay. If you're a little more spontaneous, you could also peruse Expedia's last minute deals which could secure you a cheaper stay. Look out for the green banner below the price to spot the deals. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Mesopotamia is Tuesday. The most expensive day to stay around Mesopotamia is Monday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to refine your preferences, such as your budget, preferred location, and the type of hotel you desire. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly accommodations currently available. To discover the best prices and deals, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save some money by combining your hotel reservations in Mesopotamia with your flights and activities through an Expedia package. ### Find the best attractions near Mesopotamia Mesopotamia, Argentina, offers a fantastic blend of entertainment, adventure, and family-friendly activities. Explore stunning national parks and enjoy the breathtaking scenery while engaging in outdoor experiences that cater to thrill-seekers and nature lovers alike. With a variety of points of interest, your vacation in Mesopotamia promises unforgettable adventures for all types of travelers. - **Portal Carambola:** Located 22.5km from Mesopotamia, this national park offers thrilling adventures amidst stunning scenery and a vibrant outdoor atmosphere, perfect for nature enthusiasts seeking unique experiences in Argentina. ### Best time to go to Mesopotamia The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 80.1°F (26.700000000000003°C) | Light Rain | Sunny | Moderately High | Average | | February | 77.7°F (25.4°C) | Light Rain | Mostly Sunny | | | | March | 72.9°F (22.700000000000003°C) | Light Rain | Mostly Sunny | Moderately High | Average | | April | 66.7°F (19.3°C) | Light Rain | Mostly Sunny | Average | Average | | May | 59.5°F (15.3°C) | Light Rain | Mostly Sunny | | | | June | 60.1°F (15.6°C) | Light Rain | Mostly Sunny | | | | July | 53.4°F (11.9°C) | Light Rain | Mostly Sunny | Average | Slightly High | | August | 63.7°F (17.6°C) | Light Rain | Mostly Sunny | Average | Slightly High | | September | 60.6°F (15.9°C) | Light Rain | Mostly Sunny | Average | Average | | October | 65.8°F (18.8°C) | Light Rain | Mostly Sunny | Average | Average | | November | 72.3°F (22.4°C) | Light Rain | Sunny | Moderately High | Average | | December | 77.0°F (25.0°C) | Light Rain | Sunny | Average | Slightly High | ### The nearest major airports for your trip to Mesopotamia To reach Mesopotamia, Argentina, you can fly into three major airports. Posadas (PSS-Libertador General Jose de San Martin) is 222.1km away, with nearby hotels such as [La Mision Posadas Hotel](https://www.expedia.ca/Posadas-Hotels-La-Mision-Posadas-Hotel.h4190115.Hotel-Information) and [Continental Posadas Hotel](https://www.expedia.ca/Posadas-Hotels-Continental-Posadas-Hotel.h24990493.Hotel-Information) both offering airport transportation services. Resistencia (RES-Resistencia Intl.) is located 181.9km from Mesopotamia, featuring hotels like [Gala Hotel y Convenciones](https://www.expedia.ca/Resistencia-Hotels-Gala-Hotel-Y-Convenciones.h12370608.Hotel-Information), which also provides transport. Corrientes (CNQ-Corrientes Intl.) is the closest at 164.2km, with options including [La Alondra Casa De Huéspedes](https://www.expedia.ca/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) and [Turismo Hotel Casino](https://www.expedia.ca/Corrientes-Hotels-Turismo-Hotel-Casino.h11901090.Hotel-Information), both offering airport shuttle services. Each airport provides convenient access to the charming attractions of Mesopotamia. ## Recent reviews of Mesopotamia hotels ![Hathor Concordia](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg) ### Hathor Concordia 5/5 Excellent "The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional"." A verified traveller from Luquillo stayed at Hathor Concordia Posted 9 days ago [](https://expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![Holiday Inn Express Rosario by IHG](https://images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg) ### Holiday Inn Express Rosario by IHG 5/5 Excellent "It's a perfect please to stay! " A verified traveller stayed at Holiday Inn Express Rosario by IHG Posted 12 days ago [](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information) ![Amérian Hotel Casino Gala](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/a75881f1_y.jpg) ### Amérian Hotel Casino Gala 5/5 Excellent "Good check in" A verified traveller stayed at Amérian Hotel Casino Gala Posted 13 days ago [](https://expedia.ca/Resistencia-Hotels-Amerian-Hotel-Casino-Gala.h1197026.Hotel-Information) ![Holiday Inn Rosario by IHG](https://images.trvl-media.com/lodging/1000000/580000/570400/570357/61653463_y.jpg) ### Holiday Inn Rosario by IHG 5/5 Excellent "It was very well maintained, super clean and loved the smell of the room when we entered, it was soft (not aggressive) but nice, very pleasant. The bed and sheets were excellent! The cover on site parking was a good plus too and they have valet parking. " A verified traveller from Villa Lynch stayed at Holiday Inn Rosario by IHG Posted 2 weeks ago [](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Rosario.h570357.Hotel-Information) ![Club Valle Termal Resort](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710_y.jpg) ### Club Valle Termal Resort 5/5 Excellent "La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto." A verified traveller stayed at Club Valle Termal Resort Posted 1 month ago [](https://expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![Marriott Corrientes Hotel](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686_y.jpg) ### Marriott Corrientes Hotel 5/5 Excellent "Very nice hotel" A verified traveller stayed at Marriott Corrientes Hotel Posted 1 month ago [](https://expedia.ca/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) ![Wyndham Garden Campana](https://images.trvl-media.com/lodging/1000000/990000/983700/983698/1521535a_y.jpg) ### Wyndham Garden Campana 3/5 Okay "Televisor con problemas de funcionamiento. Ducha que baña todo el baño en lugar de ti. Ventana expuesta al paso de todo el público. " A verified traveller from hudson stayed at Wyndham Garden Campana Posted 11 months ago [](https://expedia.ca/Pilar-Hotels-Australis-Campana.h983698.Hotel-Information) ![O2 Hotel Gualeguaychú](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8_y.jpg) ### O2 Hotel Gualeguaychú 4/5 Good "Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. " A verified traveller stayed at O2 Hotel Gualeguaychú Posted 1 year ago [](https://expedia.ca/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![Days Inn by Wyndham Zarate](https://images.trvl-media.com/lodging/72000000/71050000/71042900/71042838/153bae1a_y.jpg) ### Days Inn by Wyndham Zarate 3/5 Okay "Room with very comfortable beds, which is the hotel's strongest point, service by the guys at breakfast very bad, no desire to work, bathroom located on the ground floor with a smell worse than a public bathroom in the city center, where I have already informed the management so that they can take action. Very nice pool for families. Good hotel for families on vacation and good breakfast!" A verified traveller stayed at Days Inn by Wyndham Zarate Posted 1 year ago [](https://expedia.ca/Zarate-Hotels-Days-Inn-Zarate.h71042838.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Mesopotamia hotel booking with Expedia? ### How much is the nightly rate at a Mesopotamia hotel? ## Explore a world of travel with Expedia - More ways to book - [Book Hotels in Mesopotamia on Expedia.com.ar ](https://www.expedia.com.ar/Mesopotamia-Hoteles.d6208836.Guia-de-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app