Photo by Lane

Mesilla Vacation Rentals

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Aug 29 - Aug 31
In two weeks
Sep 5 - Sep 7
In one month
Sep 19 - Sep 21
In two months
Oct 17 - Oct 19

Browse Select Mesilla Vacation Homes

Charming 2-bedroom adobe casita in the country and farms
Beach

Charming 2-bedroom adobe casita in the country and farms

The price is CA $166
CA $250 total
includes taxes & fees
Aug 25 - Aug 26
Charming 2-bedroom adobe casita in the country and farms
Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
Outdoor dining

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

10.0 out of 10, Exceptional, (78)
"Clean and as advertised, would stay again "
The price is CA $135
CA $315 total
includes taxes & fees
Aug 25 - Aug 26
Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
Middle Room Near Downtown (For Ladies Only)
Fridge, microwave, oven, stovetop

Middle Room Near Downtown (For Ladies Only)

9.0 out of 10, Wonderful, (2)
"Imelda did a great job of communicating before and during my trip. She is very friendly and accommodating"
The price is CA $54
CA $141 total
includes taxes & fees
Aug 25 - Aug 26
Middle Room Near Downtown (For Ladies Only)
Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio
Room

Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio

The price is CA $105
CA $256 total
includes taxes & fees
Sep 2 - Sep 3
Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio
4098/Lyle SW · Brand New Home in Beautiful Golf Course Community
Exterior detail

4098/Lyle SW · Brand New Home in Beautiful Golf Course Community

10.0 out of 10, Exceptional, (8)
"Everything here was perfect! We will definitely be staying here again! "
The price is CA $142
CA $450 total
includes taxes & fees
Sep 7 - Sep 8
4098/Lyle SW · Brand New Home in Beautiful Golf Course Community
Casa Sonoma | Spacious, Central Retreat | Peloton
Terrace/patio

Casa Sonoma | Spacious, Central Retreat | Peloton

10.0 out of 10, Exceptional, (40)
"Enjoyed our time here. Would definitely stay again. "
The price is CA $142
CA $417 total
includes taxes & fees
Aug 25 - Aug 26
Casa Sonoma | Spacious, Central Retreat | Peloton
Southwest Gem just minutes from White Sands National Park
Fridge, microwave, oven, stovetop

Southwest Gem just minutes from White Sands National Park

10.0 out of 10, Exceptional, (17)
"I would stay here again. "
The price is CA $137
CA $375 total
includes taxes & fees
Aug 25 - Aug 26
Southwest Gem just minutes from White Sands National Park
Yucca House | Views, Jetted Bath, Central Retreat
Fridge, microwave, oven, stovetop

Yucca House | Views, Jetted Bath, Central Retreat

10.0 out of 10, Exceptional, (31)
"We’ve stayed at Yucca House a few times and it is always clean and as described. Wendy is very responsive A great place to stay when in Las Cruces"
The price is CA $127
CA $432 total
includes taxes & fees
Aug 25 - Aug 26
Yucca House | Views, Jetted Bath, Central Retreat
Cheerful desert oasis home with a privacy hot tub! 1 minute to new hospital!
Fridge, microwave, oven, stovetop

Cheerful desert oasis home with a privacy hot tub! 1 minute to new hospital!

10.0 out of 10, Exceptional, (34)
"Very nice clean we were not there long just evening left next morning but we had dinner out on back patio. Very nice and peaceful "
The price is CA $131
CA $269 total
includes taxes & fees
Aug 25 - Aug 26
Cheerful desert oasis home with a privacy hot tub! 1 minute to new hospital!
Andromeda · Desert Retreat Near Red Hawk Golf Course
Fridge, microwave, oven, stovetop

Andromeda · Desert Retreat Near Red Hawk Golf Course

10.0 out of 10, Exceptional, (4)
"Traveled to Las Cruces for NM State baseball for the weekend and the property was great. Convenient and close to everything needed. Great communication by the host!"
The price is CA $217
CA $556 total
includes taxes & fees
Aug 25 - Aug 26
Andromeda · Desert Retreat Near Red Hawk Golf Course
2 bed, yard, pet friendly in Historic Mesilla.
Fridge, microwave, oven, stovetop

2 bed, yard, pet friendly in Historic Mesilla.

The price is CA $104
CA $275 total
includes taxes & fees
Aug 25 - Aug 26
2 bed, yard, pet friendly in Historic Mesilla.
Comfy SW Home with Private Yard & Mountain Views!
Exterior

Comfy SW Home with Private Yard & Mountain Views!

10.0 out of 10, Exceptional, (19)
"Wonderful place to stay for a visit to Las Cruces. Very well stocked with everything you might need for a stay away from home."
The price is CA $165
CA $520 total
includes taxes & fees
Aug 25 - Aug 26
Comfy SW Home with Private Yard & Mountain Views!
Bell Bungalow - Charming Home in Brilliant Las Cruces with AC, WiFi, and More
Terrace/patio

Bell Bungalow - Charming Home in Brilliant Las Cruces with AC, WiFi, and More

10.0 out of 10, Exceptional, (1)
"Perfect surroundings, loved the outside patio"
The price is CA $100
CA $228 total
includes taxes & fees
Aug 25 - Aug 26
Bell Bungalow - Charming Home in Brilliant Las Cruces with AC, WiFi, and More
Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.
TV, books

Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.

9.4 out of 10, Exceptional, (11)
"Very nice little place that’s close to everything in Mesilla-very enjoyable!"
The price is CA $122
CA $236 total
includes taxes & fees
Sep 5 - Sep 6
Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.
Modern Accessorized 3-Bedroom
Terrace/patio

Modern Accessorized 3-Bedroom

9.2 out of 10, Wonderful, (23)
"Clean and close to everything…"
The price is CA $151
CA $460 total
includes taxes & fees
Sep 7 - Sep 8
Modern Accessorized 3-Bedroom
Pulsar · Brand New Comfortable 4/3.5 Home Near Parks
Outdoor dining

Pulsar · Brand New Comfortable 4/3.5 Home Near Parks

9.8 out of 10, Exceptional, (37)
"Plenty of beds and space and a great central location to White Sands, Slot Canyon, and town. Thanks for making it easy!"
The price is CA $149
CA $469 total
includes taxes & fees
Aug 25 - Aug 26
Pulsar · Brand New Comfortable 4/3.5 Home Near Parks
1 queen bd/1futon full kitchen 5 mins to downtown
Fridge, microwave, oven, stovetop

1 queen bd/1futon full kitchen 5 mins to downtown

The price is CA $90
CA $253 total
includes taxes & fees
Aug 28 - Aug 29
1 queen bd/1futon full kitchen 5 mins to downtown
3/2 near Field of Dreams
Fridge, microwave, oven, stovetop

3/2 near Field of Dreams

The price is CA $116
CA $315 total
includes taxes & fees
Sep 7 - Sep 8
3/2 near Field of Dreams
Gardner Casita - Central Location
2 bedrooms, iron/ironing board, free WiFi, bed sheets

Gardner Casita - Central Location

10.0 out of 10, Exceptional, (1)
"It was a great experience. Paige and her mom are very nice and helpful. The house was clean and organized. And a big plus is the ac keeps you so nice and cool. I would highly recommend staying here. It’s also very close to lots of restaurants. "
The price is CA $119
CA $316 total
includes taxes & fees
Aug 25 - Aug 26
Gardner Casita - Central Location
2 bd/2bth near NMSU and Memorial Medical Center
Outdoor dining

2 bd/2bth near NMSU and Memorial Medical Center

The price is CA $116
CA $324 total
includes taxes & fees
Sep 7 - Sep 8
2 bd/2bth near NMSU and Memorial Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mesilla Hotel Reviews

Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla

10/10 Excellent
"Good and clean"
Jorge 2-night trip
Posted 3 days ago
Comfort Inn & Suites Las Cruces Mesilla