Title: Mesilla Vacation Home Rentals from CA $206: Search Top Private Vacation Homes for Rent | Expedia.ca [Hotels in Mesilla](https://expedia.ca/Mesilla-Hotels.d132684.Travel-Guide-Hotels)[Vacation Rentals in Mesilla](https://expedia.ca/Mesilla-Vacation-Rentals.d132684.Travel-Guide-VacationRentals)[Mesilla Car Rentals](https://expedia.ca/Car-Rentals-In-Mesilla.d132684.Car-Rental-Guide)[Mesilla Vacation Packages](https://expedia.ca/Mesilla.d132684.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/249a9bad94be11a6d3feebf081ee28b9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Lane # Mesilla Vacation Rentals ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=132684&startDate=2025-11-07&endDate=2025-11-09&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=132684&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=132684&startDate=2025-11-28&endDate=2025-11-30&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=132684&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Mesilla Vacation Homes ![Outdoor dining](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/6c9ad3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, stereo](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/afb96ccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/3d1fb213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/68dfdf11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian Mesilla 10/10 Exceptional (82) "Clean and as advertised, would stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Davis Michael B an B. CA $137 CA $315 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Mesilla-Hotels-Charming-Casita-In-Historic-Town-Of-Mesilla.h33734305.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119520000/119511600/119511579/60207b59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119520000/119511600/119511579/5dba3f4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119520000/119511600/119511579/f07a1077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/120000000/119520000/119511600/119511579/40a25fc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 bedroom near NMSU. W/D in unit/pets welcome. Las Cruces 10/10 Exceptional (1) "Padma wa an excellent host. She answered all our questions in a timely manner. I would recommend them to family and friends. Thank you for everything. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason W. CA $105 CA $267 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-1-Bedroom-Near-NMSU-WD-In-Unitpets-Welcome.h119511579.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/f396e7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/5e2c2e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/d1d65da0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/c70868a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southwest Gem just minutes from White Sands National Park Las Cruces 10/10 Exceptional (20) "The house is amazingl" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria C. CA $138 CA $379 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Las-Cruces-Hotels-Southwest-Gem-Just-Minutes-From-White-Sands-National-Park.h96018978.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119750000/119748700/119748602/f8470b4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/120000000/119750000/119748700/119748602/734976d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/120000000/119750000/119748700/119748602/4e827127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/120000000/119750000/119748700/119748602/68f510ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio Las Cruces 10/10 Exceptional (5) CA $94 CA $246 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Las-Cruces-Hotels-Desert-Getaway-3BR-Home-W-Outdoor-Kitchen-Spacious-Patio.h119748602.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87800000/87795900/87795874/30275a19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87800000/87795900/87795874/12eb2cdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/88000000/87800000/87795900/87795874/a5d4a37a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/88000000/87800000/87795900/87795874/340987b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Sonoma | Spacious, Central Retreat | Peloton Las Cruces 10/10 Exceptional (41) "Beautiful property in a great area!! We will definitely stay again when visiting Las Cruces " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paige C. CA $126 CA $394 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-NEW-Casa-Sonoma-Spacious.h87795874.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/5e425d55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/c33f9a04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/5f38f6fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/df6203ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4098/Lyle SW · Brand New Home in Beautiful Golf Course Community Las Cruces 10/10 Exceptional (9) "Clean, comfortable, Garage access, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $143 CA $448 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-4098Lyle-SW-Brand-New-Home-In-Beautiful-Golf-Course-Community.h91653050.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/85000000/84260000/84256900/84256832/29379cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/85000000/84260000/84256900/84256832/d89f2ec0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/85000000/84260000/84256900/84256832/914a9393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/85000000/84260000/84256900/84256832/631b0331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfy SW Home with Private Yard & Mountain Views! Las Cruces 10/10 Exceptional (19) "Beautiful home, plenty of rooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Evelyn Z. CA $173 CA $543 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-Comfy-SW-Home-With-Private-Yard-Mountain-Views.h84256832.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/117000000/116430000/116427100/116427013/9c2fbda8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/117000000/116430000/116427100/116427013/804959b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/117000000/116430000/116427100/116427013/65519c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/117000000/116430000/116427100/116427013/3f120326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bell Bungalow - Charming Home in Brilliant Las Cruces with AC, WiFi, and More Las Cruces 10/10 Exceptional (2) "Perfect surroundings, loved the outside patio" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura Jane M. CA $112 CA $242 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-Bell-Bungalow-Charming-Home-In-Brilliant-Las-Cruces-With-AC.h116427013.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/2e3e8863.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/cfdbd388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/52479f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/93854e6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis Las Cruces 9.6/10 Exceptional (9) CA $133 CA $275 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Las-Cruces-Hotels-Las-Cruces-Modern-3BR-Near-Downtown.h119453789.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/4b2e4ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/w1024h1518x0y18-6be1241a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/d6e83da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/w1176h800x24y0-5c70b99d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish & Comfy House with Backyard and Parking Las Cruces 10/10 Exceptional (31) "This property had everything I needed, was in a great neighborhood, modern, and incredibly comfortable. I slept so well every night and was really happy with the space. I would definitely book again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa D. CA $137 CA $442 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-Stylish-Comfy-House-With-Backyard-And-Parking.h79880444.Hotel-Information) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/92000000/91090000/91089600/91089581/9a25cf26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91090000/91089600/91089581/c1ebb22c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91090000/91089600/91089581/ac32c061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91090000/91089600/91089581/b8645c08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Unique 1-bedroom casita in Mesilla Park with hot tub Las Cruces 10/10 Exceptional (19) "We had a wonderful time in the area and the house was great and close to everything " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ken W. CA $107 CA $206 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-Unique-1-Bedroom-Casita-In-Mesilla-Park.h91089581.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114430000/114426900/114426816/e298f1d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/115000000/114430000/114426900/114426816/ce633b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114430000/114426900/114426816/8795cef9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114430000/114426900/114426816/62b58e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern High Desert 3BR Retreat Las Cruces 8.0/10 Very good (3) "Wonderful house, fully stocked with extras, great location. Host was very accessible. We had a relaxing stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jackie T. CA $88 CA $381 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-Modern-High-Desert-3BR-Retreat.h114426816.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653058/b8c89695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653058/c345cbc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653058/585fa409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653058/06a002cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4014/Russ Modern · New Home in Quiet Neighborhood - Relax and Enjoy Las Cruces 9.4/10 Exceptional (10) "Perfect layout for 2 families with kids to share. Easy walk to park and easy access to town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah P. CA $143 CA $445 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-4014Russ-Modern-Brand-New-Luxury-Home-With-Community-Pool.h91653058.Hotel-Information) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511629/19df0992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511629/ee8dda8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511629/61ba5ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511629/a1ecac07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 bed with W/D, pets ok, 5 min to Farmers Market Las Cruces CA $91 CA $259 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-2-Bed-With-WD.h119511629.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/0233181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/9c6ea49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/w6016h4012x0y4-ba94043f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/c7b17bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4 Bedroom Contemporary Model Home Las Cruces 9.4/10 Exceptional (28) "We thoroughly enjoyed our stay, though, there were a few details that we feel were lacking, easy fixes. There were no paper towels, no hand towel in the second bathroom and no wine glasses." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer T. CA $96 CA $286 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Las-Cruces-Hotels-4-Bedroom-Contemporary-Model-Home.h93494538.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/114000000/113590000/113580900/113580864/w1024h618x0y33-f8951e16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/114000000/113590000/113580900/113580864/w905h683x60y0-dd23ebf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/114000000/113590000/113580900/113580864/w907h683x58y0-c3a46b96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113590000/113580900/113580864/w1019h629x0y27-a5ea3a52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4BR/2.5BA w/ Fully operational Hot tub - Near NMSU Las Cruces 9.4/10 Exceptional (3) "We loved this house for our short stay. The yard was just big enough for our dogs to enjoy a stretch of their legs. We were comfortable and had easy access to restaurants. The home was very clean and directions were clear. Thanks for having us. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Beth E. CA $127 CA $374 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Las-Cruces-Hotels-4BR25BA-W-Fully-Operational-Hot-Tub-Near-NMSU.h113580864.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653064/85785fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653064/574ee83f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653064/f2204d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653064/9199dd42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pulsar · Brand New Comfortable 4/3.5 Home Near Parks Las Cruces 9.8/10 Exceptional (40) "The house has 2 master suites and worked out great for our families. We were very comfortable, plenty of room. It’s in a great location too. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Phyllis L. CA $159 CA $479 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Las-Cruces-Hotels-Pulsar-Brand-New-Comfortable-435-Home-Near-Parks.h91653064.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/13a9dcf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/47bb0497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, computer monitors](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/f1af3810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/4361071c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yucca House | Views, Jetted Bath, Central Retreat Las Cruces 10/10 Exceptional (33) "We had a great stay!! Perfect home!! SUPER CLEAN!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bobby L. CA $129 CA $439 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Las-Cruces-Hotels-Yucca-House-Views.h87796251.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/94000000/93530000/93520100/93520084/5b5a0016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93530000/93520100/93520084/1e855d6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93530000/93520100/93520084/c4d0d98c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/94000000/93530000/93520100/93520084/983444c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Accessorized 3-Bedroom Las Cruces 9.2/10 Wonderful (25) "Clean and close to everything…" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy & Mike k. CA $152 CA $461 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Las-Cruces-Hotels-Modern-Accessorized-3-Bedroom.h93520084.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653090/8a9b5b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653090/c327a685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653090/bbcede57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653090/06516bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Andromeda · Desert Retreat Near Red Hawk Golf Course Las Cruces 10/10 Exceptional (4) "We had a great stay. The house was beautiful and everything you need to enjoy your trip. Thank you@" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cathie W. CA $181 CA $508 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Las-Cruces-Hotels-Andromeda-Desert-Retreat-Near-Red-Hawk-Golf-Course.h91653090.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=132684&adults=2&lodging=VACATION_HOME&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesilla-Private-Vacation-Homes.d132684-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesilla-Private-Vacation-Homes.d132684-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Mesilla Hotel Reviews ![Comfort Inn & Suites Las Cruces Mesilla](//images.trvl-media.com/lodging/2000000/1360000/1353900/1353805/518ac77c_y.jpg) ### Comfort Inn & Suites Las Cruces Mesilla 10/10 Excellent "Fit in well with the local culture" [](https://expedia.ca/Las-Cruces-Hotels-Comfort-Inn-Suites-Las-Cruces-Mesilla.h1353805.Hotel-Information) ![Drury Inn & Suites Las Cruces](//images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/0bffe062_y.jpg) ### Drury Inn & Suites Las Cruces 10/10 Excellent "Dinner was awesome. Breakfast sucked; nobody eats maple sausage, and potatoes were air-fried to death. In other words, dried out. Simply put, whoever is in charge of breakfast should be let go." [](https://expedia.ca/Las-Cruces-Hotels-Drury-Inn-Suites-Las-Cruces.h1723204.Hotel-Information) ![Best Western Mission Inn](//images.trvl-media.com/lodging/1000000/30000/20600/20506/90d9a325_y.jpg) ### Best Western Mission Inn 10/10 Excellent "Front desk staff was friendly and courteous. The room was great, and the area was quiet. I will stay there again when in Las Cruces, NM" [](https://expedia.ca/Las-Cruces-Hotels-Best-Western-Mission-Inn.h20506.Hotel-Information) ![Comfort Suites University Las Cruces](//images.trvl-media.com/lodging/1000000/50000/43200/43179/3f986bbe_y.jpg) ### Comfort Suites University Las Cruces 10/10 Excellent "We booked a quick weekend getaway to attend a wedding. The day we arrived, it was raining, and the front desk allowed us to check in early with no issues. The rooms were clean, the location was perfect for the venue, and the staff were extremely friendly and accommodating. " [](https://expedia.ca/Las-Cruces-Hotels-Comfort-Suites-University-Las-Cruces.h43179.Hotel-Information) ![Days Inn by Wyndham Las Cruces](//images.trvl-media.com/lodging/1000000/20000/15100/15035/4e26c2df_y.jpg) ### Days Inn by Wyndham Las Cruces 10/10 Excellent "I always stay at Days Inn. It is close to the business " [](https://expedia.ca/Las-Cruces-Hotels-Days-Inn-By-Wyndham-Las-Cruces.h15035.Hotel-Information) ![Hotel Encanto de Las Cruces](//images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96_y.jpg) ### Hotel Encanto de Las Cruces 10/10 Excellent "Room has no fridge or microwave. Room was clean however. Wallpaper was peeling from walls" [](https://expedia.ca/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) ![Springhill Suites By Marriott Las Cruces](//images.trvl-media.com/lodging/1000000/210000/203700/203622/ee15ba4f_y.jpg) ### Springhill Suites By Marriott Las Cruces 10/10 Excellent "Would stay again." [](https://expedia.ca/Las-Cruces-Hotels-Springhill-Suites-By-Marriott-Las-Cruces.h203622.Hotel-Information) ![Comfort Suites Las Cruces I-25 North](//images.trvl-media.com/lodging/11000000/10330000/10320300/10320201/c5bb6ea5_y.jpg) ### Comfort Suites Las Cruces I-25 North 10/10 Excellent "I really enjoyed my stay, it was refreshing how clean and friendly the staff were!" [](https://expedia.ca/Las-Cruces-Hotels-Comfort-Suites-Las-Cruces-I-25-North.h10320201.Hotel-Information) ![Sleep Inn University](//images.trvl-media.com/lodging/1000000/50000/43200/43178/d3dae14e_y.jpg) ### Sleep Inn University 10/10 Excellent "The waffle machine was down and breakfast was okay but the eggs taste it weird" [](https://expedia.ca/Las-Cruces-Hotels-Sleep-Inn-University.h43178.Hotel-Information) ## Find out more about Mesilla ## Mesilla Vacation Homes information | Number of reviews | 362 | | --- | --- | | Accommodation | 180 Vacation Homes | | Lowest Price | CA $206 | | Highest Price | CA $543 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [5 Star Hotels in Las Cruces](https://www.expedia.ca/5Star-Las-Cruces-Hotels.s50-0-d2137.Travel-Guide-Filter-Hotels) - [Lodges in Anthony](https://www.expedia.ca/Anthony-Lodges.d6140995-aaLodges.Travel-Guide-Accommodation) - [B&B in Dona Ana](https://www.expedia.ca/Dona-Ana-Bed-And-Breakfast.d3000350236-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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