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Recommended hotels in Mesilla

A building with a tiled entrance, a number '2392' on the ground, and a ladder leaning against the wall.

1. Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
Mesilla
10.0 out of 10, Exceptional, (99 reviews)
"Outstanding. Will definitely stay again."
United States
Glenn N.
The price is CA $171
CA $374 total
includes taxes & fees
Nov 15 - Nov 16
Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
A large building with multiple parking lots and a clear view of the surrounding landscape.

2. Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,003 reviews)
"Everything was awesome here.The breakfast was the best!"
United States
Michael
The price is CA $134
CA $156 total
includes taxes & fees
Dec 6 - Dec 7
Comfort Inn & Suites Las Cruces Mesilla
A hotel with a stone facade, a covered entrance, and a sign reading "Curry Inn & Suites".

3. Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1,141 reviews)
"Very nice hotel."
United States
Kimberly
The price is CA $150
CA $173 total
includes taxes & fees
Dec 6 - Dec 7
Drury Inn & Suites Las Cruces
A hotel with a modern facade, multiple parking spaces, and a well-lit entrance.

4. Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1,003 reviews)
"Great place to stay on my way to final destination. Staff friendly and helpful."
United States
Lois
The price is CA $143
CA $166 total
includes taxes & fees
Dec 6 - Dec 7
Hampton Inn & Suites Las Cruces I-10
A multi-story hotel with a central entrance, balconies, and a parking area.

5. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3.0 star property
Las Cruces
8.0 out of 10, Very good, (2,397 reviews)
"Bed was great staff was very helpful."
United States
Sandra
The price is CA $84
CA $99 total
includes taxes & fees
Dec 3 - Dec 4
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
A Holiday Inn Express & Suites building with a stone facade, a covered entrance, and a sign indicating the address 2635.

6. Holiday Inn Express Hotel and Suites Las Cruces by IHG

Holiday Inn Express Hotel and Suites Las Cruces by IHG
2.5 star property
Las Cruces
7.8 out of 10, Good, (1,000 reviews)
"We enjoyed the updated room interior and it’s clean appearance, the friendly staff and good location"
United States
Robert
The price is CA $134
CA $155 total
includes taxes & fees
Dec 4 - Dec 5
Holiday Inn Express Hotel and Suites Las Cruces by IHG
A hotel with a sign reading "Ramada Palms" and a number "201" on the wall.

7. Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces
3.0 star property
Las Cruces
8.0 out of 10, Very good, (1,008 reviews)
"Great location, terrific staff"
United States
Frank
The price is CA $120
CA $139 total
includes taxes & fees
Nov 11 - Nov 12
Ramada Hotel & Conference Center by Wyndham Las Cruces
A Days Inn with a large sign, a flag, and a well-maintained entrance area.

8. Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
2.5 star property
Las Cruces
8.2 out of 10, Very good, (1,662 reviews)
"Clean room, comfy bed, easy in and out! Front desk staff were friendly and helpful."
United States
kathleen
The price is CA $71
CA $84 total
includes taxes & fees
Nov 29 - Nov 30
Days Inn by Wyndham Las Cruces
A Best Western sign with a bell above it, a building with a red roof, and a parking lot.

9. Best Western Mission Inn

Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,252 reviews)
"Excellent breakfast, super friendly and helpful staff. Will stay again."
United States
Kristin
The price is CA $113
CA $132 total
includes taxes & fees
Nov 15 - Nov 16
Best Western Mission Inn
A modern hotel with a flat roof, large windows, and a well-lit entrance.

10. Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces
3.0 star property
Las Cruces
8.4 out of 10, Very good, (1,002 reviews)
"The property and room was clean. The room was spacious and comfortable."
United States
Miriam
The price is CA $159
CA $184 total
includes taxes & fees
Nov 22 - Nov 23
Springhill Suites By Marriott Las Cruces
A hotel with a central courtyard, multiple balconies, and a stone wall.

11. Quality Inn & Suites Las Cruces - University Area

Quality Inn & Suites Las Cruces - University Area
2.5 star property
Las Cruces
7.0 out of 10, Good, (1,002 reviews)
"Well kept and offered anything I would need on a short trip. Nice location to Main Street."
United States
Sue
The price is CA $84
CA $99 total
includes taxes & fees
Nov 29 - Nov 30
Quality Inn & Suites Las Cruces - University Area
A multi-story hotel with a pool, surrounded by palm trees and a mountainous backdrop.

12. Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
3.5 star property
Las Cruces
9.0 out of 10, Wonderful, (2,228 reviews)
"The property was beautiful and very comfortable. I would definitely recommend and stay here again."
United States
Therese
The price is CA $130
CA $190 total
includes taxes & fees
Nov 24 - Nov 25
Hotel Encanto de Las Cruces
A Courtyard by Marriott hotel with a modern facade, multiple windows, and a covered entrance area.

13. Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (607 reviews)
"The service was great and location was perfect"
United States
Maria
The price is CA $215
CA $247 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard by Marriott Las Cruces at NMSU
A Comfort Suites hotel with a modern facade, a covered entrance, and a parking lot with marked spaces.

14. Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
2.5 star property
Las Cruces
8.0 out of 10, Very good, (1,006 reviews)
"Our room was clean and comfortable and we got free breakfasts"
United States
Laraine
The price is CA $107
CA $125 total
includes taxes & fees
Dec 3 - Dec 4
Comfort Suites University Las Cruces
A hotel with a modern design, featuring a covered entrance and multiple floors.

15. Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
2.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean room, great breakfast options."
United States
Susan
The price is CA $146
CA $174 total
includes taxes & fees
Dec 6 - Dec 7
Comfort Suites Las Cruces I-25 North
A hotel with a distinctive arched entrance and a clear sign reading "Hilton Garden Inn."

16. Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1,004 reviews)
"Had a great one night stay and dinner and breakfast in the restaurant.. definitely would stay again if I was passing through Las Cruces"
United States
Alejandro
The price is CA $157
CA $182 total
includes taxes & fees
Nov 22 - Nov 23
Hilton Garden Inn Las Cruces
A hotel with a sign reading "Super 8" and a stone facade.

17. Super 8 by Wyndham Las Cruces University Area

Super 8 by Wyndham Las Cruces University Area
2.0 star property
Las Cruces
5.8 out of 10, (345 reviews)
"Wonderful front counter girl."
United States
Daniel
The price is CA $83
CA $98 total
includes taxes & fees
Nov 15 - Nov 16
Super 8 by Wyndham Las Cruces University Area
A hotel with a prominent sign, a well-lit entrance, and a landscaped area with trees.

18. THE BLU BY RELIANSE

THE BLU BY RELIANSE
2.5 star property
Las Cruces
4.8 out of 10, (6 reviews)
"Had issues checking in."
United States
Janice
The price is CA $79
CA $99 total
includes taxes & fees
Nov 15 - Nov 16
THE BLU BY RELIANSE
A single-story building with a beige exterior, a garage door, and a small porch area.

19. Unique 1-bedroom casita in Mesilla Park with hot tub

Unique 1-bedroom casita in Mesilla Park with hot tub
Las Cruces
9.8 out of 10, Exceptional, (31 reviews)
"Super cute casita. Small but perfect for me and my husband. Could easily be room enough for 4! Hot tub was great and easy to use. Bed was super comfy. House was clean and well decorated. Private porch was lovely! Parking was right out front. 10/10 great stay"
United States
Reagan L.
The price is CA $127
CA $217 total
includes taxes & fees
Nov 15 - Nov 16
Unique 1-bedroom casita in Mesilla Park with hot tub
A Sleep Inn by Choice Hotels building with a parking lot and a covered entrance.

20. Sleep Inn University

Sleep Inn University
2.5 star property
Las Cruces
7.6 out of 10, Good, (1,004 reviews)
"Good stay"
United States
Nallely
The price is CA $95
CA $111 total
includes taxes & fees
Nov 30 - Dec 1
Sleep Inn University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Mesilla

Historic adobe buildings surround the plaza where Billy the Kid once stood trial in this charming town. Explore local art galleries and sample authentic Mexican cuisine at La Posta, a restaurant housed in a 19th-century stagecoach stop.

See all hotels in Mesilla
A rustic building with a wooden door, a hanging red chili, and a cactus plant.

Top reviews in Mesilla

A hotel with a stone facade, a covered entrance, and a sign reading "Curry Inn & Suites".
Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
Las Cruces

10/10 Excellent

great place, friendly staff, great accommodation, breakfast, dinner lunch, pet friendly
Canada
Giselia Dos Santos
Reviewed February 9, 2026
Drury Inn & Suites Las Cruces

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