Title: Mesagne Vacation Rentals from CA $150: Short-Term Rentals for 2026 | Expedia.ca [Mesagne Travel Guide](https://expedia.ca/Mesagne.dx6048941)[Hotels in Mesagne](https://expedia.ca/Mesagne-Hotels.d6048941.Travel-Guide-Hotels)[Flights to Mesagne](https://expedia.ca/Cheap-Flights-To-Mesagne.d6048941.Travel-Guide-Flights)[Mesagne Car Rentals](https://expedia.ca/Car-Rentals-In-Mesagne.d6048941.Car-Rental-Guide)[Mesagne Vacation Packages](https://expedia.ca/Mesagne.d6048941.Destination-Travel-Guides) ![Sanctuary Church of Mater Domini. Mesagne. Puglia. Italy.](https://images.trvl-media.com/place/6048941/3cab0deb-bc54-44bb-a685-9df9c53e56cb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Mesagne Vacation Rentals - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 25 - Dec 26](https://www.expedia.ca/Hotel-Search?regionId=6048941&startDate=2025-12-25&endDate=2025-12-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 26 - Dec 27](https://www.expedia.ca/Hotel-Search?regionId=6048941&startDate=2025-12-26&endDate=2025-12-27&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6048941&startDate=2025-12-26&endDate=2025-12-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6048941&startDate=2026-01-02&endDate=2026-01-04&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesagne-Vacation-Rentals.d6048941.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesagne-Vacation-Rentals.d6048941.Travel-Guide-VacationRentals) ## Top Mesagne Hotel Reviews ![Dama Bianca Boutique Hotel Ostuni ](https://images.trvl-media.com/lodging/92000000/91580000/91577800/91577799/d2e78f3e_y.jpg) ### Dama Bianca Boutique Hotel Ostuni 10/10 Excellent "Very nice place to stay, convenient, safe and spacious " [](https://expedia.ca/Ostuni-Hotels-Dama-Bianca-Boutique-Hotel-Ostuni.h91577799.Hotel-Information) ![Tobacco Suite](https://images.trvl-media.com/lodging/13000000/12440000/12432400/12432369/dfbb036a_y.jpg) ### Tobacco Suite 10/10 Excellent "Beautiful room, staff were so lovely, breakfast fantastic. It takes seconds to be in the historic centre. Brilliant." [](https://expedia.ca/Mesagne-Hotels-Tobacco-Suite.h12432369.Hotel-Information) ![Hotel Orientale](https://images.trvl-media.com/lodging/3000000/2320000/2315600/2315560/45b267c1_y.jpg) ### Hotel Orientale 10/10 Excellent "A very good hotel in an excellent location. Clean, spacious, modern room. A very good breakfast buffet with a lot of selections. What is most noteworthy is the staff. Andre and his wife at the reception desk were welcoming, personable and very helpful with local knowledge and advice. At breakfast Toni and Antonio took great care to insure that all was in order and well stocked. Such was the care, that Toni actually would frequently stir the food in the steam trays to insure that the food still looked edible at the end of the breakfast hours. Though I travel 6 months of the year, that is something I rarely see. Highly recommend this Hotel." [](https://expedia.ca/Brindisi-Hotels-Hotel-Orientale.h2315560.Hotel-Information) ![Hotel La Terra](https://images.trvl-media.com/lodging/5000000/4950000/4943500/4943424/aa97474d_y.jpg) ### Hotel La Terra 10/10 Excellent "Francesco made it all happen. He picked us up, recommended fabulous places to eat, etc. Clean beautiful white sheets on the beds here and everywhere in Puglia. The shuttle to the hotel if you come by rental car is great. It is a funky layout of a hotel but for the budget value traveler it is on our list. " [](https://expedia.ca/Ostuni-Hotels-Hotel-La-Terra.h4943424.Hotel-Information) ![Hotel Monte Sarago](https://images.trvl-media.com/lodging/4000000/3890000/3883900/3883810/ad4a255b_y.jpg) ### Hotel Monte Sarago 10/10 Excellent "Clean room with easy parking" [](https://expedia.ca/Ostuni-Hotels-Hotel-Monte-Sarago.h3883810.Hotel-Information) ![Arryvo](https://images.trvl-media.com/lodging/84000000/83460000/83450600/83450529/0cdb37a4_y.jpg) ### Arryvo 10/10 Excellent "Perfect " [](https://expedia.ca/Lecce-Hotels-Arryvo.h83450529.Hotel-Information) ![Grande Albergo Internazionale](https://images.trvl-media.com/lodging/4000000/3650000/3644100/3644041/066a2ec4_y.jpg) ### Grande Albergo Internazionale 10/10 Excellent "Lovely hotel on the waters edge in Brindisi. We had a beautiful room which was quite large. The breakfast had plenty of variety.Check out the area around the hotel; very historic. We enjoyed visiting the city and highly recommend this establishment." [](https://expedia.ca/Brindisi-Hotels-Grande-Albergo-Internazionale.h3644041.Hotel-Information) ![Palazzo Sant'Anna Lecce](https://images.trvl-media.com/lodging/23000000/22580000/22579500/22579414/1c3491cf_y.jpg) ### Palazzo Sant'Anna Lecce 10/10 Excellent "Exceptional level of service. Exceptional breakfast. Having snacks available in the shared areas in the evening was a great plus. Value for money was outstanding, for example the sauna and pool. Location perfect for exploring Lecce on foot or Sarento by car." [](https://expedia.ca/Lecce-Hotels-Palazzo-SantAnna-Lecce.h22579414.Hotel-Information) ![Palazzo Virgilio](https://images.trvl-media.com/lodging/2000000/1260000/1255600/1255562/f19ab7af_y.jpg) ### Palazzo Virgilio 10/10 Excellent "The" [](https://expedia.ca/Brindisi-Hotels-Palazzo-Virgilio.h1255562.Hotel-Information) ## Find out more about Mesagne You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded. As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Mesagne. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do. ## Explore a world of travel with Expedia - Trending destinations on Expedia.ca ### Trending destinations on Expedia.ca - [Canmore Vacation Rentals ](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Kelowna Vacation Rentals ](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals) - [Whistler Vacation Rentals ](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Victoria Vacation Rentals ](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals) - [Vancouver Vacation Rentals ](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals ](https://www.expedia.ca/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Tofino Vacation Rentals ](https://www.expedia.ca/Tofino-Vacation-Rentals.d6094955.Travel-Guide-VacationRentals) - [Calgary Vacation Rentals ](https://www.expedia.ca/Calgary-Vacation-Rentals.d178245.Travel-Guide-VacationRentals) - [Costa Rica Vacation Rentals ](https://www.expedia.ca/Destinations-In-Costa-Rica.d42.Vacation-Rental-Destinations) - [Vancouver Island Vacation Rentals ](https://www.expedia.ca/Vancouver-Island-Vacation-Rentals.d6058387.Travel-Guide-VacationRentals) - [Puerto Vallarta Vacation Rentals ](https://www.expedia.ca/Puerto-Vallarta-Vacation-Rentals.d180016.Travel-Guide-VacationRentals) - [Hawaii Vacation Rentals ](https://www.expedia.ca/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Toronto Vacation Rentals ](https://www.expedia.ca/Toronto-Vacation-Rentals.d178314.Travel-Guide-VacationRentals) - [Banff Vacation Rentals ](https://www.expedia.ca/Banff-Vacation-Rentals.d10550.Travel-Guide-VacationRentals) - [Penticton Vacation Rentals ](https://www.expedia.ca/Penticton-Vacation-Rentals.d4135.Travel-Guide-VacationRentals) - [Osoyoos Vacation Rentals ](https://www.expedia.ca/Osoyoos-Vacation-Rentals.d181782.Travel-Guide-VacationRentals) - [Mont Tremblant Vacation Rentals ](https://www.expedia.ca/Mont-Tremblant-Vacation-Rentals.d55374.Travel-Guide-VacationRentals) - [Big White Ski Resort Vacation Rentals ](https://www.expedia.ca/Big-White-Ski-Resort-Vacation-Rentals.d6058319.Travel-Guide-VacationRentals) - [Ontario Vacation Rentals ](https://www.expedia.ca/Destinations-In-Ontario.d11178.Vacation-Rental-Destinations) - [British Columbia Vacation Rentals ](https://www.expedia.ca/Destinations-In-British-Columbia.d11117.Vacation-Rental-Destinations) - [Prince Edward Island Vacation Rentals ](https://www.expedia.ca/Destinations-In-Prince-Edward-Island.d6058122.Vacation-Rental-Destinations) - [Québec Vacation Rentals ](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals) ## Frequently asked questions ### Can I find vacation rentals in Mesagne? ### What are some of the best vacation home rentals that Mesagne has to offer? ### How many vacation rentals are there in Mesagne? ### What can I see and do in Mesagne? ### What are vacation rentals like in Mesagne? ### Expedia's Latest Trends Hotels - [Hotels in Polignano a Mare](https://expedia.ca/Polignano-A-Mare-Hotels.d6048893.Travel-Guide-Hotels) - [Hotels in Sorrento](https://expedia.ca/Sorrento-Hotels.d9716.Travel-Guide-Hotels) - [Hotels in Taormina](https://expedia.ca/Taormina-Hotels.d4915.Travel-Guide-Hotels) - [Hotels in Florence](https://expedia.ca/Florence-Hotels.d1222.Travel-Guide-Hotels) - [Hotels in Positano](https://expedia.ca/Positano-Hotels.d4330.Travel-Guide-Hotels) - [Hotels in Bari](https://expedia.ca/Bari-Hotels.d680.Travel-Guide-Hotels) - [Hotels in Monopoli](https://expedia.ca/Monopoli-Hotels.d4955.Travel-Guide-Hotels) - [Hotels in Lecce](https://expedia.ca/Lecce-Hotels.d8479.Travel-Guide-Hotels) Flights - [Cheap Flights to Brindisi](https://expedia.ca/Cheap-Flights-To-Brindisi.d526.Travel-Guide-Flights) - [Cheap Flights to Bari](https://expedia.ca/Cheap-Flights-To-Bari.d680.Travel-Guide-Flights) Cars - [Car rentals in Bari](https://expedia.ca/Car-Rentals-In-Bari.d680.Car-Rental-Guide) Activities - [Things to do in Monopoli](https://expedia.ca/Things-To-Do-In-Monopoli.d4955.Travel-Guide-Activities) - [Things to do in Bari](https://expedia.ca/Things-To-Do-In-Bari.d680.Travel-Guide-Activities) - [Things to do in San Giovanni Rotondo](https://expedia.ca/Things-To-Do-In-San-Giovanni-Rotondo.d6023886.Travel-Guide-Activities) - [Things to do in Polignano a Mare](https://expedia.ca/Things-To-Do-In-Polignano-A-Mare.d6048893.Travel-Guide-Activities) - [Things to do in Brindisi](https://expedia.ca/Things-To-Do-In-Brindisi.d526.Travel-Guide-Activities) Packages - [Bari Vacations](https://expedia.ca/Bari.d680.Destination-Travel-Guides) General - [Visit Polignano a Mare](https://expedia.ca/Polignano-A-Mare.dx6048893) - [Visit Brindisi](https://expedia.ca/Brindisi.dx526) - [Visit Cisternino](https://expedia.ca/Cisternino.dx6024940) - [Visit Temu](https://expedia.ca/Temu.dx6168461) - [Visit Porto Cesareo](https://expedia.ca/Porto-Cesareo.dx6047158) - [Visit Vieste](https://expedia.ca/Vieste.dx6023654) - [Visit Monteleone di Puglia](https://expedia.ca/Monteleone-Di-Puglia.dx3000472780) - [Visit Alberobello](https://expedia.ca/Alberobello.dx6046360) - [Visit Diso](https://expedia.ca/Diso.dx6275148) - [Visit Peschici](https://expedia.ca/Peschici.dx6023424) - [Visit Monopoli](https://expedia.ca/Monopoli.dx4955) - [Visit Gallipoli](https://expedia.ca/Gallipoli.dx603111) - [Visit Roseto Valfortore](https://expedia.ca/Roseto-Valfortore.dx3000464198) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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