Mesagne Vacation Rentals from CA $109: Short-Term Rentals for 2026

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Our top choices for Mesagne vacation rentals

A modern interior with a staircase, wooden flooring, and a small indoor garden.

1. Mezzaluna Luxury Rooms - Matrimoniale

Mesagne

CA $140 total

includes taxes & fees

Nov 24 - Nov 25

A beach with clear turquoise water and white sand.

2. Private 1-bedroom vacation home in Mesagne

Mesagne

CA $215 total

includes taxes & fees

Nov 12 - Nov 13

A hotel room with a large bed, a chair, a table, and a staircase leading to another room.

3. Volta Apartment with Private Terrace, Wi-Fi and Air Conditioning

Mesagne

CA $301 total

includes taxes & fees

Nov 23 - Nov 24

A staircase with a wrought iron railing, a chandelier, and a sofa in a warmly lit interior space.

4. Apartment 'Dimora La Reggia' with Private Pool, Wi-Fi and Air Conditioning

Mesagne

CA $309 total

includes taxes & fees

Nov 24 - Nov 25

A balcony with a wicker chair, a sliding glass door, and a view of neighboring buildings.

5. Mezzaluna Luxury Rooms - Mono Home

Mesagne

CA $168 total

includes taxes & fees

Nov 24 - Nov 25

A modern bathroom with a freestanding bathtub, a large potted plant, and a minimalist design.

6. Mezzaluna Luxury Rooms - Suite Mono

Mesagne

CA $283 total

includes taxes & fees

Nov 25 - Nov 26

A model lighthouse on a table with a chair and a door in the background.

7. Affittacamere AlleVolte

Brindisi Historic Center

Chiara

CA $122 total

includes taxes & fees

Nov 12 - Nov 13

A spa room with a sauna, a glass-enclosed shower, and a wooden bench.

8. Villa Neviera - Wine Resort and Spa

San Donaci

Markus

CA $109 total

includes taxes & fees

Nov 13 - Nov 14

A living room with a flat-screen TV on a wooden cabinet, a small Christmas tree, and a potted plant.

9. TOI Apartments

Brindisi Historic Center

Leonid

CA $111 total

includes taxes & fees

Nov 25 - Nov 26

A wall with multiple black and white photographs of cityscapes and bridges, a clock, and three vases on a wooden dresser.

10. Casa Vacanze Asariel Splendido Appartamento Vista Mare e Centro Città

Brindisi Historic Center

ALEXANDRA

CA $132 total

includes taxes & fees

Nov 14 - Nov 15

A narrow street with buildings on both sides, a bell tower in the distance, and a balcony with potted plants.

11. A casa dei miei

San Pietro Vernotico

jan

CA $152 total

includes taxes & fees

Nov 12 - Nov 13

A multi-story building with balconies and windows, surrounded by trees.

12. Dada's Cozy Appartaments

Carovigno

CA $112 total

includes taxes & fees

Nov 19 - Nov 20

A bedroom with a bed, a mirror, a ladder, and a glass door leading to a bathroom.

13. FILIA SOLIS - Old Town SUITEs & SPA

Brindisi Historic Center

COLIN

CA $196 total

includes taxes & fees

Nov 12 - Nov 13

A hotel room with a large bed, a bedside table, a nightstand, a bathroom visible through an open door, and a small window.

14. Vie Del Salento - Primitivo with Wi-Fi and Air Conditioning

San Pancrazio Salentino

CA $100 total

includes taxes & fees

Nov 12 - Nov 13

A modern indoor pool with a water feature, arched ceilings, and a reception area visible through an archway.

15. Dimora Nettare

Brindisi Historic Center

Lawrence

CA $235 total

includes taxes & fees

Dec 4 - Dec 5

A hotel room with a bed, a desk, two chairs, a lamp, and framed architectural drawings on the wall.

16. The Arcs and the Stars

Brindisi Historic Center

Hector P.

CA $249 total

includes taxes & fees

Dec 1 - Dec 2

A dining area with a view of the ocean through a mural, a white balcony railing, and a door leading to another room.

17. Apartment 'Il Posto del Cuore' close to City Centre with Terrace & A/C

Brindisi

Anonymous traveller

CA $385 total

includes taxes & fees

Nov 12 - Nov 13

A modern house with a deck, outdoor seating, and a garden.

18. Il Nostro Sogno - Madonna by Tiny Away

Provincia di Brindisi

CA $201 total

includes taxes & fees

Nov 12 - Nov 13

19. Villa Ghetta Country House

Leverano

Stefania

CA $103 total

includes taxes & fees

Nov 13 - Nov 14

A bedroom with a bed, a dresser, a mirror, and a chandelier.

20. Holiday home 'Da Gigetto Tuturano' with private garden and Wi-Fi

Tuturano

CA $521 total

includes taxes & fees

Nov 22 - Nov 23

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Top Mesagne Hotel Reviews

Palazzo Sant'Anna Lecce

10/10 Excellent

"Beautiful hotel located in a Renaissance palace in quiet location in the historic center of Lecce, not far from via Giuseppe Libertini, with tasteful renovation and decoration. Gorgeous. And the staff were very professional, courteous, and kind."

Le Dune Suite Hotel

10/10 Excellent

"Location, location , location, the Dune suite hotel is perfectly located in Porto Cesareo, about 3-4 km from the historical center with many good restaurants. Most importantly this hotel has a beautiful beach across the street, on the Ionian sea, 24 Celsius and calm 10/10 for the first week of October. At this period 2 transats and a parasol are complimentary. There is a nice bar and an evening restaurant plus takeout counters for lunch that you can eat at the beach. The rooftop pool setup of the hotel is very nice with lounge furniture and a perfect view of the sunset! Breakfast is absolutely complete and delicious. Would recommend without any doubt."

Masseria Donna Menga

10/10 Excellent

"We absolutely loved our stay at Masseria Donna Menga. It’s such a beautiful, peaceful and relaxing place. The gardens and pool area are stunning, the rooms are lovely and the service was excellent. The staff were all so friendly and welcoming! Everything was just perfect, and we would happily come back!"

Find out more about Mesagne

Everything you need to know about Mesagne vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesagne vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesagne vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mesagne vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mesagne. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Mesagne vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Mesagne vacation rentals we have selected for you start as low as CA $109 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Mesagne rentals

At Expedia, we put the best Mesagne vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mesagne rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesagne vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesagne. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find vacation rentals in Mesagne?

Yes, there are vacation rentals near well known attractions in Mesagne, or you can select a more secluded option if you want a relaxing place to stay. Mesagne is known for its monuments and museums. Make sure you have time to check out the restaurants while you're in the area.

What are some of the best vacation home rentals that Mesagne has to offer?

Perfect oasis among Olive Trees and Private Pool, for an authentic experience!: This vacation home rental outside of Mesagne is located in a rural location and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and a selection of games so you can immerse yourself in your vacation.

How many vacation rentals are there in Mesagne?

Choose from 7 Expedia vacation rentals in Mesagne for a memorable vacation.

What can I see and do in Mesagne?

Cultural attractions include Teatro Comunale di Mesagne, whereas Mesagne Dog Park is a spot to enjoy nature. Other places in town to visit include Mesagne Castle and Piazza Orsini del Balzo.

What are vacation rentals like in Mesagne?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Mesagne. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of privacy away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive choice for a family getaway.

Mesagne Vacation Rentals

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Check prices for these dates

Our top choices for Mesagne vacation rentals

1. Mezzaluna Luxury Rooms - Matrimoniale

2. Private 1-bedroom vacation home in Mesagne

3. Volta Apartment with Private Terrace, Wi-Fi and Air Conditioning

4. Apartment 'Dimora La Reggia' with Private Pool, Wi-Fi and Air Conditioning

5. Mezzaluna Luxury Rooms - Mono Home

6. Mezzaluna Luxury Rooms - Suite Mono

7. Affittacamere AlleVolte

8. Villa Neviera - Wine Resort and Spa

9. TOI Apartments

10. Casa Vacanze Asariel Splendido Appartamento Vista Mare e Centro Città

11. A casa dei miei

12. Dada's Cozy Appartaments

13. FILIA SOLIS - Old Town SUITEs & SPA

14. Vie Del Salento - Primitivo with Wi-Fi and Air Conditioning

15. Dimora Nettare

16. The Arcs and the Stars

17. Apartment 'Il Posto del Cuore' close to City Centre with Terrace & A/C

18. Il Nostro Sogno - Madonna by Tiny Away

19. Villa Ghetta Country House

20. Holiday home 'Da Gigetto Tuturano' with private garden and Wi-Fi

Find vacation rentals that suit your style

Top Mesagne Hotel Reviews

Palazzo Sant'Anna Lecce

Find out more about Mesagne

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