Mesagne Vacation Rentals from CA $118: Short-Term Rentals for 2026

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Mesagne vacation rentals

1. Apartment 'Dimora La Reggia' with Private Pool, Wi-Fi and Air Conditioning

Mesagne

CA $1,766 total

includes taxes & fees

Aug 22 - Aug 23

2. 1 Bedroom Private vacation home in Mesagne

Mesagne

3. Luxury suites in the historic center of Mesagne

Mesagne

CA $383 total

includes taxes & fees

Aug 24 - Aug 25

4. Mezzaluna Luxury Rooms - Matrimoniale

Mesagne

5. The Ideal Shelter for Families "Discover the heart of Mesagne

Mesagne

CA $183 total

includes taxes & fees

Sep 4 - Sep 5

6. Trullo 'Pietra800' with Private Terrace, Private Garden and Air Conditioning

Mesagne

CA $418 total

includes taxes & fees

Sep 1 - Sep 2

7. FILIA SOLIS - Old Town SUITEs & SPA

Brindisi Historic Center

COLIN

CA $214 total

includes taxes & fees

Sep 5 - Sep 6

Hot stone massages, Swedish massages, Thai massages, massages

8. Dimora Nettare

Brindisi Historic Center

Kevin

CA $182 total

includes taxes & fees

Sep 8 - Sep 9

Townhome, Balcony, City View | Living area

9. BlueBlu Apartment

Brindisi Historic Center

CA $202 total

includes taxes & fees

Aug 17 - Aug 18

Comfort Apartment, Terrace | Living area

10. TOI Apartments

Brindisi Historic Center

Leonid

CA $168 total

includes taxes & fees

Sep 10 - Sep 11

11. Donnosanto Hotel

Carovigno

Joseph

CA $132 total

includes taxes & fees

Sep 6 - Sep 7

12. Casa Vacanze Asariel Splendido Appartamento Vista Mare e Centro Città

Brindisi Historic Center

ALEXANDRA

CA $145 total

includes taxes & fees

Aug 28 - Aug 29

1 bedroom, iron/ironing board, WiFi, bed sheets

13. Suite-Near Airport & Hospital

Brindisi

CA $116 total

includes taxes & fees

Aug 12 - Aug 13

14. Masseria della Piana Ostuni

Ostuni

Guy

CA $432 total

includes taxes & fees

Aug 29 - Aug 30

15. Apartment Nuvola Rione Cappuccini

Brindisi

Randall H.

CA $174 total

includes taxes & fees

Aug 24 - Aug 25

Outdoor pool, pool umbrellas, sun loungers

16. SA Suites

Trepuzzi

"Amazing stay at this Masseria which exceeded all expectations. From the beautiful interiors and location, to the delicious breakfast and dinner cooked by the hosts, our stay was fantastic. Nick and Anja are incredible hosts and the Masseria is even more beautiful in real life. We loved waking up among the beautiful tree groves and enjoying the days by the pool. The rooms are big and beautifully furnished. In the evenings, the hosts treated us to a delicious dinner and signature cocktails on...

Marius

CA $527 total

includes taxes & fees

Aug 28 - Aug 29

17. Domus ASTRA

Brindisi Historic Center

Mike

CA $136 total

includes taxes & fees

Sep 4 - Sep 5

18. Center 3

Brindisi Historic Center

CA $255 total

includes taxes & fees

Sep 1 - Sep 2

19. Donnosanto Residence

Carovigno

Eyal

CA $424 total

includes taxes & fees

Aug 13 - Aug 14

20. Center 1

Brindisi Historic Center

CA $246 total

includes taxes & fees

Sep 1 - Sep 2

View all properties

Find vacation rentals that suit your style

Apartments

Aparthotels

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Top Mesagne Hotel Reviews

Masseria Malvindi

10/10 Excellent

"A+ , no complaints !"

Conchiglia Azzurra Resort & Beach

8/10 Good

"Overall, we had a good stay at Conchiglia Azzurra. The rooms are fairly modern, clean, spacious, and well maintained, making for a pretty comfortable stay. The staff were always courteous and helpful whenever we needed assistance. One suggestion that would significantly improve the guest experience would be to include beach access amenities with the room. Offering each room one beach umbrella and two loungers for the duration of the stay—similar to what Le Dune provides—would be a welcome addition. When you’re already paying a premium to stay at the hotel, it’s a bit disappointing to have to pay extra each day for an umbrella and loungers. Including these as part of the room rate would add great value and make the overall experience even better. Overall, we enjoyed our stay and would recommend Conchiglia Azzurra, especially if this small improvement were considered."

Ostuni a Mare

10/10 Excellent

"The property is even better than advertised! It is a gorgeous resort and very convenient for young families. The little train will take you to the private beach in minutes. The 3 pools are wonderful, but the most noteworthy thing to mention is the incredible staff!!! Amazing, attentive, always busy and making sure that the guests have everything. There is nothing I did not like (except maybe the security guard at the villas’ gate who was extremely rude because we were at the wrong gate to exit)… My husband and I would come back and recommend it wholeheartedly!"

VISTA Ostuni

10/10 Excellent

"Our stay at VISTA Ostuni was nothing short of exceptional. The staff made us feel genuinely welcomed from the moment we arrived, providing warm, attentive service that was flawless throughout our stay. The property itself is absolutely stunning—beautifully designed, impeccably maintained, and every detail reflects true luxury. The panoramic views of Ostuni and the surrounding countryside are breathtaking, especially at sunset. Every meal was a delight, from the incredible breakfast to the outstanding dining experiences. The quality of the food, the atmosphere, and the service exceeded all expectations. If you're looking for a luxurious, relaxing, and unforgettable stay in Puglia, VISTA Ostuni is simply outstanding. We can't wait to return!"

Find out more about Mesagne

Everything you need to know about Mesagne vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesagne vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesagne vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mesagne vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mesagne. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Mesagne vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Mesagne vacation rentals we have selected for you start as low as CA $118 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Mesagne rentals

At Expedia, we put the best Mesagne vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mesagne rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesagne vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesagne. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Mesagne?

Yes, there are vacation rentals near well known attractions in Mesagne, or you can select a more secluded option if you want a relaxing place to stay. Mesagne is known for its monuments and museums. Make sure you have time to check out the restaurants while you're in the area.

What are some of the best vacation home rentals that Mesagne has to offer?

Lecce: Holiday at Salento. A vintage atmosphere in the heart of Lecce: This vacation home rental outside of Mesagne is located next to a golf course and has a balcony, a selection of books, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in Mesagne?

Choose from 5 Expedia vacation rentals in Mesagne for a memorable vacation.

What can I see and do in Mesagne?

Explore the area and family-friendly sights such as Carrisiland Resort, or get out into nature at a spot like Mesagne Dog Park. Mesagne Castle and Cathedral of Brindisi are a couple of places you'll find in the larger area.

What are vacation rentals like in Mesagne?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Mesagne. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of privacy away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive choice for a family getaway.

Mesagne Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Mesagne vacation rentals

1. Apartment 'Dimora La Reggia' with Private Pool, Wi-Fi and Air Conditioning

2. 1 Bedroom Private vacation home in Mesagne

3. Luxury suites in the historic center of Mesagne

4. Mezzaluna Luxury Rooms - Matrimoniale

5. The Ideal Shelter for Families "Discover the heart of Mesagne

6. Trullo 'Pietra800' with Private Terrace, Private Garden and Air Conditioning

7. FILIA SOLIS - Old Town SUITEs & SPA

8. Dimora Nettare

9. BlueBlu Apartment

10. TOI Apartments

11. Donnosanto Hotel

12. Casa Vacanze Asariel Splendido Appartamento Vista Mare e Centro Città

13. Suite-Near Airport & Hospital

14. Masseria della Piana Ostuni

15. Apartment Nuvola Rione Cappuccini

16. SA Suites

17. Domus ASTRA

18. Center 3

19. Donnosanto Residence

20. Center 1

Find vacation rentals that suit your style

Top Mesagne Hotel Reviews

Masseria Malvindi

Find out more about Mesagne

Explore a world of travel with Expedia

Frequently asked questions

Expedia's Latest Trends

Go further with the Expedia app