Title: Book the Best Mesa SPA Resorts - Spa Hotels in Mesa, CO | Expedia.ca [Hotels in Mesa](https://expedia.ca/Mesa-Hotels.d179955.Travel-Guide-Hotels)[Vacation Rentals in Mesa](https://expedia.ca/Mesa-Vacation-Rentals.d179955.Travel-Guide-VacationRentals)[Flights to Mesa](https://expedia.ca/Cheap-Flights-To-Mesa.d179955.Travel-Guide-Flights)[Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Mesa.d179955.Car-Rental-Guide)[Mesa Vacation Packages](https://expedia.ca/Mesa.d179955.Destination-Travel-Guides) ![View from the North Rim of Mesa Verde National Park at the Park Point Overlook towards Cortez Colorado USA](https://images.trvl-media.com/place/179955/8b988b59-f9ca-4db5-b799-975982c07c74.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Mesa, CO - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mesa Spa Hotels Tonight [Jan 4 - Jan 5](https://www.expedia.ca/Hotel-Search?regionId=179955&startDate=2026-01-04&endDate=2026-01-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 5 - Jan 6](https://www.expedia.ca/Hotel-Search?regionId=179955&startDate=2026-01-05&endDate=2026-01-06&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=179955&startDate=2026-01-09&endDate=2026-01-11&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=179955&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesa hotels with a spa ![Dinner served](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/3ecd4143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/w3000h2022x0y2-11965b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/2e7baa84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/0b44c017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine Country Inn Palisade [](https://www.expedia.ca/Grand-Junction-Hotels-Wine-Country-Inn-Palisade.h2108693.Hotel-Information) Palisade 9.6/10 Exceptional (1003) "Beautiful property, great breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy [](https://www.expedia.ca/Grand-Junction-Hotels-Wine-Country-Inn-Palisade.h2108693.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-19&endDate=2026-01-20®ionId=179955&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Mesa Hotel Reviews ![Grand Vista Hotel](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/7dc2f4eb_y.jpg) ### Grand Vista Hotel 10/10 Excellent "All of the above! " [](https://expedia.ca/Grand-Junction-Hotels-Grand-Vista-Hotel.h14746.Hotel-Information) ![Clarion Inn Grand Junction](https://images.trvl-media.com/lodging/1000000/20000/10400/10322/64eb32ff_y.jpg) ### Clarion Inn Grand Junction 10/10 Excellent "Very helpful staff. Fun facility. " [](https://expedia.ca/Grand-Junction-Hotels-Clarion-Inn-Grand-Junction.h10322.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Grand Junction](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/89cb7554_y.jpg) ### La Quinta Inn & Suites by Wyndham Grand Junction 10/10 Excellent "The room was super clean, the bed was the best sleep I've had in months. Thank you La Quinta for caring and taking care of your property. If I visit again- def staying here again. 😎" [](https://expedia.ca/Grand-Junction-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Grand-Junction.h84495.Hotel-Information) ![Grand River Hotel](https://images.trvl-media.com/lodging/2000000/1120000/1113200/1113167/96982b51_y.jpg) ### Grand River Hotel 10/10 Excellent "Good beds. Very friendly staff." [](https://expedia.ca/Glenwood-Springs-Hotels-Grand-River-Hotel.h1113167.Hotel-Information) ![Grand Vista Hotel Parachute](https://images.trvl-media.com/lodging/5000000/4290000/4287400/4287357/8dd90326_y.jpg) ### Grand Vista Hotel Parachute 10/10 Excellent "The swimming pool felt cold, but the hot tub helped " [](https://expedia.ca/Glenwood-Springs-Hotels-Grand-Vista-Hotel-Parachute.h4287357.Hotel-Information) ![Comfort Inn Grand Junction I-70](https://images.trvl-media.com/lodging/1000000/10000/6100/6052/b70fb5ab_y.jpg) ### Comfort Inn Grand Junction I-70 10/10 Excellent "Nice , clean and hot breakfast" [](https://expedia.ca/Grand-Junction-Hotels-Comfort-Inn-Grand-Junction-I-70.h6052.Hotel-Information) ![SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.](https://images.trvl-media.com/lodging/5000000/4330000/4323600/4323538/48620488_y.jpg) ### SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St. 10/10 Excellent "Pool was broken and the sister pool heater was bad as well. A little disappointed for the pools. But everything else was great" [](https://expedia.ca/Grand-Junction-Hotels-SpringHill-Suites-By-Marriott-Grand-Junction-DowntownHistoric-Main-St.h4323538.Hotel-Information) ## Frequently asked questions ### How much does a spa hotel in Mesa cost? ### Is it cheaper to book a spa hotel in Mesa with flights as part of a package deal? ### Are there any unique spa experiences available in Mesa? > Awaken Zen Spa in Mesa provides distinctive treatments such as a therapeutic massage performed solely using the feet, which delivers broad, smooth pressure for deep muscle release and tension relief. They also offer a 120-minute Ultimate Luxury 50 Stone Treatment using warm bamboo tools and hot stones strategically placed to melt tension and boost circulation. Additionally, their head-focused treatments combine hot and cold facial stones, cupping, lymphatic massage, scalp massage, and aromatherapy for deep relaxation. > > > Mesa also has a Medical Spa & Chiropractic Care centre specialising in advanced laser aesthetics, Botox, fillers, microneedling, hydradermabrasion facials, and PRP joint injections, offering a medical approach to spa wellness. ### How can I save on a spa hotel in Mesa with Expedia? ### Can I cancel my spa hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [4 Star Hotels in Clifton ](https://www.expedia.ca/4Star-Clifton-Hotels.s40-0-d180936.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Cedaredge ](https://www.expedia.ca/Cedaredge-Hotels-Cheap-Hotels.0-0-d602751-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Cedaredge ](https://www.expedia.ca/Cedaredge-Hotels-Hotels-With-Hot-Tubs.0-0-d602751-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - 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