Title: The 10 Best Hotels Near Mayo Clinic Florida, Jacksonville from CA $177 | Expedia.ca

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![Jacksonville_MayoClinicFlorida_6127706_04](https://images.trvl-media.com/place/6127706/6901ae4a-327b-40c7-92f0-e912ea036578.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

Tonight

[Jan 26 - Jan 27](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2026-01-26&endDate=2026-01-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 27 - Jan 28](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2026-01-27&endDate=2026-01-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Mayo Clinic Florida hotels

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/b2da11bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/d0436ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lake view](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/1e6ff5e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/c1792edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Jacksonville At Mayo Clinic

[](https://www.expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information)

0.8 km from Mayo Clinic Florida

9.4/10

Exceptional

(127 reviews)

"Great place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy

CA $246

CA $279 total

includes taxes & fees

Feb 19 - Feb 20

[](https://www.expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/b5b95b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/3b4310c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/c8f0b79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/5b1f404a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn By Marriott Jacksonville - Mayo Clinic Area

[](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)

1.1 km from Mayo Clinic Florida

9.4/10

Exceptional

(456 reviews)

"The staff was great at check in and the bar. Room was very clean, but the couch needed to be replaced."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wayne

CA $240

CA $272 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/3ebd8af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/e22308ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/a0b6a0da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/bb7e3270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Jacksonville East

[](https://www.expedia.ca/Jacksonville-Hotels-TownePlace-Suites-By-Marriott-Jacksonville-East.h50557569.Hotel-Information)

Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida

9.2/10

Wonderful

(568 reviews)

"Very good hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Careli

CA $156

CA $177 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/Jacksonville-Hotels-TownePlace-Suites-By-Marriott-Jacksonville-East.h50557569.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/9eef35fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/6d3a7b4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/92e09e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/1bf84034.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Beach-BlvdMayo-Clinic.h2880174.Hotel-Information)

Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida

9.0/10

Wonderful

(1,002 reviews)

"Clean and spacious room. Check-in staff very efficient and professional, great breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joe

CA $156

CA $177 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Beach-BlvdMayo-Clinic.h2880174.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/0fcbe763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/620f795f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/0036a1dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8 AM to 10 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/e289e58e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)

2.6 km from Mayo Clinic Florida

8.6/10

Excellent

(1,010 reviews)

"Great location - clean & quiet "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Peter

CA $156

CA $177 total

includes taxes & fees

Jan 30 - Jan 31

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/7dde0660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/ae56473a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/3cb87b81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/76ebbc62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

[](https://www.expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)

0.4 km from Mayo Clinic Florida

8.4/10

Very good

(757 reviews)

"Great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Josiah Christine

CA $221

CA $250 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)

![BBQ/picnic area](https://images.trvl-media.com/lodging/75000000/74610000/74603400/74603302/ace2c9f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/75000000/74610000/74603400/74603302/311013a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/75000000/74610000/74603400/74603302/03ea9367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![40-inch TV with cable channels](https://images.trvl-media.com/lodging/75000000/74610000/74603400/74603302/a57fa822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Salt Air Inn & Suites

[](https://www.expedia.ca/Jacksonville-Hotels-Salt-Air-Inn-Suites.h74603302.Hotel-Information)

7.8 km from Mayo Clinic Florida

9.8/10

Exceptional

(426 reviews)

"Amazing hotel absolute gem for Jacksonville beach "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Justin

[](https://www.expedia.ca/Jacksonville-Hotels-Salt-Air-Inn-Suites.h74603302.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/322c81fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/3cc0c712.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/24802fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/5d3207b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Element Jacksonville Beach

[](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)

5.4 km from Mayo Clinic Florida

9.6/10

Exceptional

(531 reviews)

"Great place (and location)!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dale

CA $197

CA $224 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/3cc4947f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/36e9c181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/a435d2ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/59aa7122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Jacksonville - Town Center by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-Town-Center.h34413457.Hotel-Information)

Southside, 7.7 km from Mayo Clinic Florida

9.6/10

Exceptional

(1,003 reviews)

"Location, cleanliness , property , staff was amazing"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Justin

CA $167

CA $190 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-Town-Center.h34413457.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/2f9db172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/714d9afd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/18cf9eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/d12dee4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott® Jacksonville Mayport

[](https://www.expedia.ca/Jacksonville-Hotels-Towneplace-Suites-By-Marriott-Atlantic-Beach.h111923614.Hotel-Information)

10.8 km from Mayo Clinic Florida

9.8/10

Exceptional

(71 reviews)

"This was an awesome place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christine

CA $171

CA $194 total

includes taxes & fees

Feb 4 - Feb 5

[](https://www.expedia.ca/Jacksonville-Hotels-Towneplace-Suites-By-Marriott-Atlantic-Beach.h111923614.Hotel-Information)

![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/b159421b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/c2598c1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 Queen Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/fcfa2192.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/fe355a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Hotel Palms

[](https://www.expedia.ca/Jacksonville-Hotels-The-Hotel-Palms.h15784631.Hotel-Information)

7.8 km from Mayo Clinic Florida

9.6/10

Exceptional

(293 reviews)

"stayed here for an event and it was awesome"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

clayton

CA $232

CA $263 total

includes taxes & fees

Jan 27 - Jan 28

[](https://www.expedia.ca/Jacksonville-Hotels-The-Hotel-Palms.h15784631.Hotel-Information)

![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/910000/903900/903879/d3a5975c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, Oceanfront](https://images.trvl-media.com/lodging/1000000/910000/903900/903879/fbf89cc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/910000/903900/903879/08b847ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![On the beach, white sand, surfing](https://images.trvl-media.com/lodging/1000000/910000/903900/903879/1d79fb78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ponte Vedra Inn & Club

[](https://www.expedia.ca/Jacksonville-Hotels-Ponte-Vedra-Inn-Club.h903879.Hotel-Information)

6.3 km from Mayo Clinic Florida

9.4/10

Exceptional

(815 reviews)

"Amazing. Loved it "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carol

CA $679

CA $797 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Jacksonville-Hotels-Ponte-Vedra-Inn-Club.h903879.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/898b0a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 9 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/78bc0b87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/w3837h2560x3y3-801b9f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/9b491ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)

4.2 km from Mayo Clinic Florida

9.0/10

Wonderful

(1,022 reviews)

"Clean room, good breakfast and location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jesus

CA $167

CA $190 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)

![Beach/ocean view](https://images.trvl-media.com/lodging/1000000/30000/25400/25311/3171b62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25400/25311/04198d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/30000/25400/25311/b5695ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/1000000/30000/25400/25311/8a58b8d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Lodge and Club at Ponte Vedra Beach

[](https://www.expedia.ca/Jacksonville-Hotels-The-Lodge-And-Club-At-Ponte-Vedra-Beach.h25311.Hotel-Information)

6.3 km from Mayo Clinic Florida

9.4/10

Exceptional

(688 reviews)

"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

CA $684

CA $802 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Jacksonville-Hotels-The-Lodge-And-Club-At-Ponte-Vedra-Beach.h25311.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/d30ef697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/04850bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/512c8fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/97c5b971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Margaritaville Jacksonville Beach

[](https://www.expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information)

5.9 km from Mayo Clinic Florida

9.0/10

Wonderful

(3,557 reviews)

"Friendly staff, clean rooms and great atmosphere!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susan

CA $184

CA $209 total

includes taxes & fees

Jan 28 - Jan 29

[](https://www.expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/335b1fee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/fab1e174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/be234916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/fba2ad11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AC Hotel Jacksonville St Johns Town Center

[](https://www.expedia.ca/Jacksonville-Hotels-AC-Hotel-Jacksonville-ST-Johns-Town-CTR.h99777110.Hotel-Information)

Southside, 8.1 km from Mayo Clinic Florida

9.4/10

Exceptional

(176 reviews)

"Staff was excellent...highly recommend this Hotel"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Robert

CA $273

CA $309 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/Jacksonville-Hotels-AC-Hotel-Jacksonville-ST-Johns-Town-CTR.h99777110.Hotel-Information)

![On the beach](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/cd4b0791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/43c9ff41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/105ea82f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/b0d3d74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Oceanfront

[](https://www.expedia.ca/Jacksonville-Hotels-Best-Western-Oceanfront.h119095.Hotel-Information)

5.7 km from Mayo Clinic Florida

9.0/10

Wonderful

(1,010 reviews)

"Great location, breakfast was delicious "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

CA $173

CA $196 total

includes taxes & fees

Jan 27 - Jan 28

[](https://www.expedia.ca/Jacksonville-Hotels-Best-Western-Oceanfront.h119095.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/8cf3943d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/76bd5c14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/w3995h2667x0y0-516d4609.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 2 Queen Beds, Balcony, Oceanfront](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/b29f7074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Springhill Suites By Marriott Jacksonville Beach Oceanfront

[](https://www.expedia.ca/Jacksonville-Hotels-Springhill-Suites-By-Marriott-Jacksonville-Beach-Oceanfront.h90175988.Hotel-Information)

5.8 km from Mayo Clinic Florida

9.0/10

Wonderful

(631 reviews)

"The hotel was great! Very clean room and staff were very courteous and professional"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mike

CA $244

CA $277 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Jacksonville-Hotels-Springhill-Suites-By-Marriott-Jacksonville-Beach-Oceanfront.h90175988.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/ac80791a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/a10175e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/2040edc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/c5d5c944.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Jacksonville Beach by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)

4.6 km from Mayo Clinic Florida

9.2/10

Wonderful

(1,005 reviews)

"Great for the quick stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aaron

CA $158

CA $179 total

includes taxes & fees

Feb 4 - Feb 5

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/892900/892823/24c987fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/900000/892900/892823/bd75f975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/900000/892900/892823/d12ebf20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Brewpub, beach views, open daily](https://images.trvl-media.com/lodging/1000000/900000/892900/892823/779495e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Points by Sheraton Jacksonville Beachfront

[](https://www.expedia.ca/Jacksonville-Hotels-Four-Points-By-Sheraton-Jacksonville-Beachfront.h892823.Hotel-Information)

5.6 km from Mayo Clinic Florida

9.0/10

Wonderful

(1,002 reviews)

"Beds very comfortable. Check-in seamless. I loved my stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Pizza

CA $267

CA $303 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Jacksonville-Hotels-Four-Points-By-Sheraton-Jacksonville-Beachfront.h892823.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-09&endDate=2026-02-10&regionId=6127706&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Mayo Clinic Florida Hotel Reviews

![Modern Coastal Retreat w/ Private Pool](https://images.trvl-media.com/lodging/120000000/119750000/119746000/119745989/8544d748_y.jpg)

### Modern Coastal Retreat w/ Private Pool

10/10 Excellent

"We would definitely stay here again. The host is fabulous, very quick to respond. The home had everything that we needed and more. Thanks for a great stay! "

[](https://expedia.ca/Jacksonville-Hotels-Modern-Coastal-Retreat-W-Private-Pool.h119745989.Hotel-Information)

![Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/w3837h2560x3y3-801b9f38_y.jpg)

### Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

10/10 Excellent

"Good location, clean room"

[](https://expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)

![Hilton Jacksonville At Mayo Clinic](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/a30920c9_y.jpg)

### Hilton Jacksonville At Mayo Clinic

10/10 Excellent

"The staff and hotel were wonderful! "

[](https://expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information)

![Amazing Centrally Located Home in Peaceful Area](https://images.trvl-media.com/lodging/101000000/100610000/100608400/100608360/32fbbd37_y.jpg)

### Amazing Centrally Located Home in Peaceful Area

10/10 Excellent

"The home was clean, and had enough space for our family."

[](https://expedia.ca/Jacksonville-Hotels-Amazing-Centrally-Located-Home-In-Peaceful-Area.h100608360.Hotel-Information)

![Tranquility by Mayo w/ Heated Pool Mins to Beach](https://images.trvl-media.com/lodging/84000000/83060000/83055800/83055766/44a30e91_y.jpg)

### Tranquility by Mayo w/ Heated Pool Mins to Beach

10/10 Excellent

"The ease of moving in, unit was VERY clean, great back yard, nice pool, but was too cold in the Jacksonville area to dip our toes in. "

[](https://expedia.ca/Jacksonville-Hotels-1-Mi-To-Mayo-Private-Heated-Pool-5-Mins-To-Beach.h83055766.Hotel-Information)

![Margaritaville Jacksonville Beach](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/863d9eb6_y.jpg)

### Margaritaville Jacksonville Beach

10/10 Excellent

"Nice and clean"

[](https://expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information)

![Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/0fcbe763_y.jpg)

### Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

10/10 Excellent

"Excellent! Thank you!"

[](https://expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)

![Holiday Inn Express Jacksonville Beach by IHG](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/ac80791a_y.jpg)

### Holiday Inn Express Jacksonville Beach by IHG

10/10 Excellent

"Great for the quick stay! "

[](https://expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)

![Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/7227c750_y.jpg)

### Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

10/10 Excellent

"Clean and spacious room. Check-in staff very efficient and professional, great breakfast."

[](https://expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Beach-BlvdMayo-Clinic.h2880174.Hotel-Information)

## Hotels near other Mayo Clinic Florida attractions

### Adventure Landing

4.1/5 (157 reviews)

This amusement park east of Jacksonville is a fun daytrip for the whole family with thrilling rides, exciting attractions for kids and a shipwreck-themed waterpark.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6128080)

### Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6068663)

### Windsor Commons Shopping Center

You can enjoy retail therapy at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's great live music and acclaimed theater scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558033805)

### Harbor City Municipal Golf Course

Enjoy a round of golf in Jacksonville at Harbor City Municipal Golf Course. Amble around the area's beautiful beaches or attend a sporting event. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621563220206)

### Cradle Creek Preserve

Explore the great outdoors at Cradle Creek Preserve, a lovely green space in Jacksonville Beach. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621561766841)

### Jacksonville Beach Golf Club

3.9/5 (58 reviews)

Enjoy a round of golf in Jacksonville Beach at Jacksonville Beach Golf Club. Wander the beautiful beaches and seaside in this romantic area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621561766896)

### South Beach Park and Sunshine Playground

4.3/5 (44 reviews)

South Beach Park and Sunshine Playground is just one of the places to see in Jacksonville Beach, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or experience the acclaimed theater scene in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621561892262)

### Gonzales Park

4.1/5 (31 reviews)

Gonzales Park is just one of the places to see in Jacksonville Beach, so why not enjoy the other things to explore during your travels? Stroll along the seaside or experience the acclaimed theater scene in this romantic area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558033757)

## Frequently asked questions

### What are the top-rated hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area is situated within an 18-minute walking distance from Mayo Clinic Florida and has a solid review rating of 9.4\. This 3-star hotel provides travellers with a complimentary buffet breakfast each morning, alongside amenities such as an outdoor pool and a well-equipped fitness centre available 24/7\. The presence of a kitchen in every room, complete with a refrigerator and microwave, allows travellers to prepare meals at their convenience, enhancing their stay in Jacksonville.
> 
>   
> [Element Jacksonville Beach](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)
> 
>   
> Element Jacksonville Beach is a delightful 3-star hotel located just 8.0 km from Mayo Clinic Florida, with an impressive review rating of 9.6\. This hotel offers a variety of amenities including an outdoor pool, a fitness centre, and free breakfast—ideal for travellers looking for a refreshing stay. Unique features like a hydromassage showerhead and a fully equipped kitchen with a dishwasher and stovetop elevate the experience, making it a great choice for travellers seeking both relaxation and functionality.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Holiday Inn Express Jacksonville Beach by IHG is just 6.9 km from Mayo Clinic Florida, with an excellent review rating of 9.2\. This inviting hotel features an outdoor pool and offers a daily buffet breakfast to start the day right. Guests will appreciate the free internet access and the relaxing terrace, while the nearby a nearby beach adds an enjoyable outdoor experience to their visit.

### What hotels are within walking distance to Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area is a welcoming 3-star hotel just an 18-minute walk from Mayo Clinic Florida, rated 9.4 by travellers. Guests appreciate the spacious rooms featuring kitchen amenities such as a dishwasher and microwave, along with the convenience of free daily breakfast. The outdoor pool and 24-hour fitness centre provide great options for relaxation and exercise, while the garden area enhances the overall ambiance.
> 
>   
> [Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches](https://www.expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)
> 
>   
> Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches offers a prime location only 3 minutes from Mayo Clinic Florida, a review rating of 8.4\. This 3-star hotel features an outdoor pool and a well-equipped fitness centre, ensuring travellers have ample opportunities to unwind. With modern amenities like premium bedding and a snack bar, visitors can enjoy a comfortable stay close to their medical appointments.

### How much is a hotel near Mayo Clinic Florida?

### What are the most popular family-friendly hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area, rated 9.4 by travellers, is only an 18-minute walk from Mayo Clinic Florida. This 3-star hotel is designed with families in mind, offering spacious suites with kitchen facilities and free rollaway beds. Guests can take advantage of the outdoor pool, 24-hour fitness centre, and complimentary breakfast to start their day right.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Holiday Inn Express Jacksonville Beach by IHG offers a family-friendly experience just 6.9 km from Mayo Clinic Florida, with a great traveler rating score of 9.2\. Families will appreciate the free cribs, connecting rooms, and outdoor pool. Additional amenities include a complimentary breakfast served daily and easy access to the nearby beach, making it a great option for relaxation after a visit to the clinic.
> 
>   
> [Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)
> 
>   
> Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG is a family-friendly hotel located just 4.8 km from Mayo Clinic Florida. With a review rating of 8.4, this hotel features amenities such as free cribs, connecting rooms, and complimentary buffet breakfast, ensuring a comfortable stay for families. Guests can also enjoy an outdoor pool and easy access to nearby shopping and golf courses.

### Which hotels near Mayo Clinic Florida offer the best views?

> [Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)
> 
>   
> Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG is a welcoming 3-star hotel located just 4.8 km from Mayo Clinic Florida, rated 8.4 by travellers. This hotel features an outdoor pool with golf course views, perfect for relaxation after a day of appointments. Guests can enjoy a complimentary buffet breakfast daily, along with access to fitness facilities and free self-parking. A nearby shopping centre adds to the convenience, making it an ideal choice for those seeking both comfort and scenic views.

### What are the best affordable hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area is a 3-star hotel situated a short 18-minute walk from Mayo Clinic Florida, with a great traveler rating score of 9.4\. This hotel is perfect for families, offering free breakfast daily and a kitchen in each suite for convenient meal preparation. Additional amenities include an outdoor pool, 24-hour fitness facilities, and free self-parking, making it a practical choice for extended stays or quick visits alike.
> 
>   
> [Element Jacksonville Beach](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)
> 
>   
> Element Jacksonville Beach is a 3-star hotel located just 8.0 km from Mayo Clinic Florida, with an impressive review rating of 9.6\. This family-friendly hotel offers complimentary breakfast options, including a cooked breakfast and free WiFi, ensuring a pleasant start to your day. Guests can enjoy amenities such as an outdoor pool, fitness centre, and fully-equipped kitchens in select rooms, making it an ideal choice for those looking for a comfortable and affordable stay.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Holiday Inn Express Jacksonville Beach by IHG is located 6.9 km from Mayo Clinic Florida and has a solid review rating of 9.2\. This hotel provides a complimentary buffet breakfast and free WiFi, suiting families and budget-conscious travellers. Guests can also take advantage of the outdoor pool, free self-parking, and nearby beach access, ensuring a relaxing and enjoyable experience during their stay.

### Are there any hotels with pools close to Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Just an 18-minute walk from Mayo Clinic Florida, the 3-star Residence Inn By Marriott Jacksonville offers a fantastic outdoor pool equipped with sun loungers and a poolside bar, perfect for relaxation after a long day. Rated 9.4 by travellers, this hotel features free buffet breakfast, a fitness centre available 24/7, and spacious rooms complete with kitchen facilities, making it ideal for both short and extended stays.
> 
>   
> [Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)
> 
>   
> Located 5.6 km from Mayo Clinic Florida, the Hampton Inn features an inviting outdoor pool with accessible options and sun loungers, rated 8.8 by travellers. Guests can enjoy a complimentary breakfast daily and access to fitness facilities. With nearby beach access, this hotel offers a blend of relaxation and convenience, perfect for those needing nearby the clinic.
> 
>   
> [Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)
> 
>   
> Situated 4.8 km from Mayo Clinic Florida, the Holiday Inn Express boasts an outdoor pool surrounded by sun loungers and umbrellas, rated 8.4 by travellers. Guests can indulge in a free breakfast each morning and benefit from modern amenities including a fitness centre. This hotel is a great choice for those looking for comfort and convenience close to medical facilities.

### What are the best pet-friendly hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> The Residence Inn By Marriott Jacksonville - Mayo Clinic Area is just an 18-minute walk from Mayo Clinic Florida and boasts an impressive review rating of 9.4\. This 3-star hotel welcomes pets with amenities such as in-room pet accommodations and service animals. Guests can enjoy a complimentary buffet breakfast, an outdoor pool, and a well-equipped fitness centre, making it a great choice for travellers seeking comfort and convenience.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Located 6.9 km from Mayo Clinic Florida, the Holiday Inn Express Jacksonville Beach by IHG is a fantastic option for pet owners, rated 9.2 by travellers. This hotel allows pets and offers amenities like free breakfast and an outdoor pool. Guests will appreciate the nearby sandy beach, making it perfect for leisurely walks with their dogs after a day at the clinic.
> 
>   
> [Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)
> 
>   
> The Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area is a pet-friendly haven situated just 5.6 km from Mayo Clinic Florida, with a great traveler rating score of 8.8\. This hotel features in-room pet accommodations and a complimentary breakfast. Guests can unwind at the outdoor pool or explore the nearby beach, ensuring a pleasant stay for both pets and their owners.

### Can I book a fully refundable hotel close to Mayo Clinic Florida?

### Can I find Expedia discounts for hotels near Mayo Clinic Florida?

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- [Flights to Jacksonville Beach ](https://www.expedia.ca/Cheap-Flights-To-Jacksonville-Beach.d8196.Travel-Guide-Flights)
- [Flights from Ottawa to Jacksonville Beach ](https://www.expedia.ca/lp/flights/178296/8196/ottawa-to-jacksonville-beach)
- [Flights from Toronto to Jacksonville Beach ](https://www.expedia.ca/lp/flights/178314/8196/toronto-to-jacksonville-beach)

- [Adventure Landing ](https://www.expedia.ca/Adventure-Landing-Jacksonville.d6128080.Vacation-Attraction)
- [Visit Beach Cities Jacksonville ](https://www.expedia.ca/Beach-Cities-Jacksonville.dx6062930)
- [Jacksonville Beach Vacations ](https://www.expedia.ca/Jacksonville-Beach.d8196.Destination-Travel-Guides)
- [Visit Jacksonville Beach ](https://www.expedia.ca/Jacksonville-Beach.dx8196)
- [Visit Isle of Palms ](https://www.expedia.ca/Jacksonville-Isle-Of-Palms.dx553248635976480347)
- [Visit Sans Pareil ](https://www.expedia.ca/Jacksonville-Sans-Pareil.dx553248635975852002)

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- [Jacksonville Beach Vacation Rentals ](https://www.expedia.ca/Jacksonville-Beach-Vacation-Rentals.d8196.Travel-Guide-VacationRentals)

- [Things to do in Jacksonville Beach ](https://www.expedia.ca/Things-To-Do-In-Jacksonville-Beach.d8196.Travel-Guide-Activities)