JACKSONVILLE RIVERWALK, FL

Find hotels near Mayo Clinic Florida, Jacksonville from CA $169

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic Florida hotels

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (250 reviews)
"Beautiful hotel!! It was extremely quiet and we all slept amazing!!"
United States
christine
The price is CA $228
CA $258 total
includes taxes & fees
Jul 4 - Jul 5
Hilton Jacksonville At Mayo Clinic

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (534 reviews)
"My family stayed here. Clean hotel and great breakfast."
United States
Ryan
The price is CA $227
CA $258 total
includes taxes & fees
Jul 3 - Jul 4
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,025 reviews)
"Convenient location; clean and comfortable room; very friendly and helpful front desk staff"
United States
Tonya
The price is CA $172
CA $195 total
includes taxes & fees
Jun 21 - Jun 22
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,008 reviews)
"Nice clean easy stay. Staff interaction was all positive as well. Decent breakfast too."
United States
Heidi
The price is CA $149
CA $169 total
includes taxes & fees
Jun 21 - Jun 22
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (776 reviews)
"Enjoyed our stay"
United States
Alan
The price is CA $212
CA $241 total
includes taxes & fees
Jun 27 - Jun 28
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Element by Marriott Jacksonville Beach

Element by Marriott Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (560 reviews)
"Best hotel ever 😊"
United States
Tablo
The price is CA $212
CA $241 total
includes taxes & fees
Jun 14 - Jun 15
Element by Marriott Jacksonville Beach

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,004 reviews)
"The hotel and the staff were amazing! My family had a wonderful time there, the rooms were clean and a good breakfast! Excellent location!"
United States
Maria
The price is CA $170
CA $193 total
includes taxes & fees
Jun 21 - Jun 22
Holiday Inn Express Jacksonville Beach by IHG

The Hotel Palms Poolside

The Hotel Palms Poolside
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (480 reviews)
"Very clean and quiet, even with the festival in AB. Felt very safe. Loved the pool area!"
United States
Liza
The price is CA $252
CA $286 total
includes taxes & fees
Jun 11 - Jun 12
The Hotel Palms Poolside

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
Deerwood, 7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (77 reviews)
"Great staff, new hotel, a pleasure to stay in"
United States
Kevin
The price is CA $172
CA $195 total
includes taxes & fees
Jun 15 - Jun 16
Hyatt Studios Jacksonville/St Johns Town Center

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,135 reviews)
"Great location not too far from beaches restsurants, and shopping."
United States
Donna L.
The price is CA $194
CA $220 total
includes taxes & fees
Jun 28 - Jun 29
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (302 reviews)
"Clean, room was very nice, staff was helpful"
United States
Angela
The price is CA $239
CA $271 total
includes taxes & fees
Jun 15 - Jun 16
The Hotel Palms Courtyard

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (4,053 reviews)
"Great property right on the beach, excellent views and food and plenty of spacious rooms"
United States
Lakesha
The price is CA $233
CA $265 total
includes taxes & fees
Jun 14 - Jun 15
Margaritaville Jacksonville Beach

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (824 reviews)
"Lovely hotel. Can’t beat rooms on the ocean. Too bad the pool and pool facilities are under construction."
United States
Mary
The price is CA $696
CA $817 total
includes taxes & fees
Jun 14 - Jun 15
Ponte Vedra Inn & Club

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (696 reviews)
"Loved the soacious rooms and the beach was very clean"
Canada
Marsha
The price is CA $627
CA $739 total
includes taxes & fees
Jun 11 - Jun 12
The Lodge and Club at Ponte Vedra Beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Great stay"
United States
Adam
The price is CA $201
CA $228 total
includes taxes & fees
Jun 15 - Jun 16
Best Western Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (713 reviews)
"Room was clean, lots to do and place to eat close by. Breakfast was good. Overall a good hotel."
United States
Yadiel
The price is CA $272
CA $308 total
includes taxes & fees
Jun 22 - Jun 23
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,010 reviews)
"Great place to stay"
United States
Clyde
The price is CA $179
CA $203 total
includes taxes & fees
Jun 29 - Jun 30
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,005 reviews)
"Very nice property and staff"
United States
BONINA
The price is CA $272
CA $309 total
includes taxes & fees
Jun 28 - Jun 29
Four Points by Sheraton Jacksonville Beachfront

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (207 reviews)
"Great stay! Highly recommend and tons to do in the area."
United States
Adam
The price is CA $250
CA $283 total
includes taxes & fees
Jun 18 - Jun 19
AC Hotel Jacksonville St Johns Town Center

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,672 reviews)
"Good breakfast and great amenities with the pool, beach and tiki barand grill. "
United States
Hillary
The price is CA $261
CA $296 total
includes taxes & fees
Jun 24 - Jun 25
Hampton Inn Jacksonville Beach/Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic Florida

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Breakfast, lunch and dinner served
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
250 reviews
View
Lobby
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
534 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
9.0
Wonderful
1,025 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,008 reviews
View
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
8.4
Very good
776 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Frequently asked questions

What are the top-rated hotels near Mayo Clinic Florida?
Finding the perfect stay near Mayo Clinic Florida can enhance your visit, especially when exploring top-rated hotels that offer comfort and convenience.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area is situated within an 18-minute walking distance from Mayo Clinic Florida and has a solid review rating of 9.4. This 3-star hotel provides travellers with a complimentary buffet breakfast each morning, alongside amenities such as an outdoor pool and a well-equipped fitness centre available 24/7. The presence of a kitchen in every room, complete with a refrigerator and microwave, allows travellers to prepare meals at their convenience, enhancing their stay in Jacksonville.

Element Jacksonville Beach

Element Jacksonville Beach is a delightful 3-star hotel located just 8.0 km from Mayo Clinic Florida, with an impressive review rating of 9.6. This hotel offers a variety of amenities including an outdoor pool, a fitness centre, and free breakfast—ideal for travellers looking for a refreshing stay. Unique features like a hydromassage showerhead and a fully equipped kitchen with a dishwasher and stovetop elevate the experience, making it a great choice for travellers seeking both relaxation and functionality.

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG is just 6.9 km from Mayo Clinic Florida, with an excellent review rating of 9.2. This inviting hotel features an outdoor pool and offers a daily buffet breakfast to start the day right. Guests will appreciate the free internet access and the relaxing terrace, while the nearby a nearby beach adds an enjoyable outdoor experience to their visit.
What hotels are within walking distance to Mayo Clinic Florida?
Discover the convenience of staying near Mayo Clinic Florida with these top-rated hotels that provide comfort and accessibility for your visit.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area is a welcoming 3-star hotel just an 18-minute walk from Mayo Clinic Florida, rated 9.4 by travellers. Guests appreciate the spacious rooms featuring kitchen amenities such as a dishwasher and microwave, along with the convenience of free daily breakfast. The outdoor pool and 24-hour fitness centre provide great options for relaxation and exercise, while the garden area enhances the overall ambiance.

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches offers a prime location only 3 minutes from Mayo Clinic Florida, a review rating of 8.4. This 3-star hotel features an outdoor pool and a well-equipped fitness centre, ensuring travellers have ample opportunities to unwind. With modern amenities like premium bedding and a snack bar, visitors can enjoy a comfortable stay close to their medical appointments.
How much is a hotel near Mayo Clinic Florida?
Staying near Mayo Clinic Florida is a treat, with plenty of hotels from CA $169 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during weekends or around public holidays.
What are the most popular family-friendly hotels near Mayo Clinic Florida?
For families visiting Mayo Clinic Florida, these top-rated hotels offer a perfect blend of comfort and convenience during your stay in Jacksonville.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area, rated 9.4 by travellers, is only an 18-minute walk from Mayo Clinic Florida. This 3-star hotel is designed with families in mind, offering spacious suites with kitchen facilities and free rollaway beds. Guests can take advantage of the outdoor pool, 24-hour fitness centre, and complimentary breakfast to start their day right.

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG offers a family-friendly experience just 6.9 km from Mayo Clinic Florida, with a great traveler rating score of 9.2. Families will appreciate the free cribs, connecting rooms, and outdoor pool. Additional amenities include a complimentary breakfast served daily and easy access to the nearby beach, making it a great option for relaxation after a visit to the clinic.

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG is a family-friendly hotel located just 4.8 km from Mayo Clinic Florida. With a review rating of 8.4, this hotel features amenities such as free cribs, connecting rooms, and complimentary buffet breakfast, ensuring a comfortable stay for families. Guests can also enjoy an outdoor pool and easy access to nearby shopping and golf courses.
Which hotels near Mayo Clinic Florida offer the best views?
Discover top-rated hotels near Mayo Clinic Florida that not only provide comfort but also stunning views.

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG is a welcoming 3-star hotel located just 4.8 km from Mayo Clinic Florida, rated 8.4 by travellers. This hotel features an outdoor pool with golf course views, perfect for relaxation after a day of appointments. Guests can enjoy a complimentary buffet breakfast daily, along with access to fitness facilities and free self-parking. A nearby shopping centre adds to the convenience, making it an ideal choice for those seeking both comfort and scenic views.
What are the best affordable hotels near Mayo Clinic Florida?
Finding affordable and comfortable accommodations near Mayo Clinic Florida is essential for travellers seeking a smooth experience. Here are some top-rated options that cater to both convenience and budget.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area is a 3-star hotel situated a short 18-minute walk from Mayo Clinic Florida, with a great traveler rating score of 9.4. This hotel is perfect for families, offering free breakfast daily and a kitchen in each suite for convenient meal preparation. Additional amenities include an outdoor pool, 24-hour fitness facilities, and free self-parking, making it a practical choice for extended stays or quick visits alike.

Element Jacksonville Beach

Element Jacksonville Beach is a 3-star hotel located just 8.0 km from Mayo Clinic Florida, with an impressive review rating of 9.6. This family-friendly hotel offers complimentary breakfast options, including a cooked breakfast and free WiFi, ensuring a pleasant start to your day. Guests can enjoy amenities such as an outdoor pool, fitness centre, and fully-equipped kitchens in select rooms, making it an ideal choice for those looking for a comfortable and affordable stay.

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG is located 6.9 km from Mayo Clinic Florida and has a solid review rating of 9.2. This hotel provides a complimentary buffet breakfast and free WiFi, suiting families and budget-conscious travellers. Guests can also take advantage of the outdoor pool, free self-parking, and nearby beach access, ensuring a relaxing and enjoyable experience during their stay.
Are there any hotels with pools close to Mayo Clinic Florida?
For those seeking a refreshing dip during their stay near Mayo Clinic Florida, there are excellent hotels with pools in Jacksonville. Here are some top-rated options to consider.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Just an 18-minute walk from Mayo Clinic Florida, the 3-star Residence Inn By Marriott Jacksonville offers a fantastic outdoor pool equipped with sun loungers and a poolside bar, perfect for relaxation after a long day. Rated 9.4 by travellers, this hotel features free buffet breakfast, a fitness centre available 24/7, and spacious rooms complete with kitchen facilities, making it ideal for both short and extended stays.

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Located 5.6 km from Mayo Clinic Florida, the Hampton Inn features an inviting outdoor pool with accessible options and sun loungers, rated 8.8 by travellers. Guests can enjoy a complimentary breakfast daily and access to fitness facilities. With nearby beach access, this hotel offers a blend of relaxation and convenience, perfect for those needing nearby the clinic.

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Situated 4.8 km from Mayo Clinic Florida, the Holiday Inn Express boasts an outdoor pool surrounded by sun loungers and umbrellas, rated 8.4 by travellers. Guests can indulge in a free breakfast each morning and benefit from modern amenities including a fitness centre. This hotel is a great choice for those looking for comfort and convenience close to medical facilities.
What are the best pet-friendly hotels near Mayo Clinic Florida?
Searching for the best pet-friendly hotels near Mayo Clinic Florida? Look no further, as these top-rated options ensure a comfortable stay for both you and your furry companions.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

The Residence Inn By Marriott Jacksonville - Mayo Clinic Area is just an 18-minute walk from Mayo Clinic Florida and boasts an impressive review rating of 9.4. This 3-star hotel welcomes pets with amenities such as in-room pet accommodations and service animals. Guests can enjoy a complimentary buffet breakfast, an outdoor pool, and a well-equipped fitness centre, making it a great choice for travellers seeking comfort and convenience.

Holiday Inn Express Jacksonville Beach by IHG

Located 6.9 km from Mayo Clinic Florida, the Holiday Inn Express Jacksonville Beach by IHG is a fantastic option for pet owners, rated 9.2 by travellers. This hotel allows pets and offers amenities like free breakfast and an outdoor pool. Guests will appreciate the nearby sandy beach, making it perfect for leisurely walks with their dogs after a day at the clinic.

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

The Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area is a pet-friendly haven situated just 5.6 km from Mayo Clinic Florida, with a great traveler rating score of 8.8. This hotel features in-room pet accommodations and a complimentary breakfast. Guests can unwind at the outdoor pool or explore the nearby beach, ensuring a pleasant stay for both pets and their owners.
Can I book a fully refundable hotel close to Mayo Clinic Florida?
Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Mayo Clinic Florida", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.
Can I find Expedia discounts for hotels near Mayo Clinic Florida?
Sign in to your account to unlock instant savings and access Member Prices on Expedia. Members always get our best prices, so join for free and look for great discounts on top hotels near Mayo Clinic Florida.

Explore a world of travel with Expedia