Title: The 10 Best Hotels Near Mayo Clinic Florida, Jacksonville from CA $170 | Expedia.ca

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![Jacksonville_MayoClinicFlorida_6127706_04](https://images.trvl-media.com/place/6127706/6901ae4a-327b-40c7-92f0-e912ea036578.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

Tonight

[Mar 13 - Mar 14](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2026-03-13&endDate=2026-03-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 14 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2026-03-14&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Mayo Clinic Florida hotels

![Lobby lounge](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/b5b95b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/5b1f404a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/c8f0b79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/8626ba46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn By Marriott Jacksonville - Mayo Clinic Area

[](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)

1.1 km from Mayo Clinic Florida

9.4/10

Exceptional

(470 reviews)

"Great stay! Clean room, friendly staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sabrena

CA $222

CA $252 total

includes taxes & fees

Mar 20 - Mar 21

[](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/b2da11bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/c1792edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/d0436ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/b1b680e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Jacksonville At Mayo Clinic

[](https://www.expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information)

0.8 km from Mayo Clinic Florida

9.4/10

Exceptional

(174 reviews)

"Great place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy

CA $234

CA $266 total

includes taxes & fees

Apr 4 - Apr 5

[](https://www.expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/3ebd8af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/e22308ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/a7e8a27c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/bb7e3270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Jacksonville East

[](https://www.expedia.ca/Jacksonville-Hotels-TownePlace-Suites-By-Marriott-Jacksonville-East.h50557569.Hotel-Information)

Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida

9.2/10

Wonderful

(587 reviews)

"Very nice accommodation , clean , and comfortable"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kevin

CA $165

CA $187 total

includes taxes & fees

Apr 6 - Apr 7

[](https://www.expedia.ca/Jacksonville-Hotels-TownePlace-Suites-By-Marriott-Jacksonville-East.h50557569.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/9eef35fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/92e09e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/1ba0722a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/6d3a7b4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Beach-BlvdMayo-Clinic.h2880174.Hotel-Information)

Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida

9.0/10

Wonderful

(1,001 reviews)

"Nice room nice stay friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thomas

CA $149

CA $170 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Beach-BlvdMayo-Clinic.h2880174.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/0fcbe763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/1373ce48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8 AM to 10 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/e289e58e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/620f795f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)

2.6 km from Mayo Clinic Florida

8.8/10

Excellent

(1,023 reviews)

"The staff was very friendly and knowledgeable and the morning breakfast was very good. Will be staying again in the future "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly

CA $153

CA $173 total

includes taxes & fees

Mar 22 - Mar 23

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/7dde0660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/ae56473a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/36a2496a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/3cb87b81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

[](https://www.expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)

0.4 km from Mayo Clinic Florida

8.4/10

Very good

(766 reviews)

"Room very clear; staff friendly and helpful; safe parking with accessibility to Mayo Clinic "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nancy

CA $219

CA $249 total

includes taxes & fees

Apr 3 - Apr 4

[](https://www.expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/322c81fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/24802fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/w5565h3712x0y0-2f0fd935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/5d3207b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Element Jacksonville Beach

[](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)

5.4 km from Mayo Clinic Florida

9.6/10

Exceptional

(540 reviews)

"Great place (and location)!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dale

CA $219

CA $249 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/3cc4947f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/36e9c181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/59aa7122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/dffb8ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Jacksonville - Town Center by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-Town-Center.h34413457.Hotel-Information)

Southside, 7.7 km from Mayo Clinic Florida

9.6/10

Exceptional

(1,000 reviews)

"Great location, friendly staff, nice rooms, great breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michelle

CA $160

CA $182 total

includes taxes & fees

Apr 2 - Apr 3

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-Town-Center.h34413457.Hotel-Information)

![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/b9cd2404.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/fe355a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/c2598c1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/c349655b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Hotel Palms

[](https://www.expedia.ca/Jacksonville-Hotels-The-Hotel-Palms.h15784631.Hotel-Information)

7.8 km from Mayo Clinic Florida

9.6/10

Exceptional

(294 reviews)

"stayed here for an event and it was awesome"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

clayton

CA $257

CA $292 total

includes taxes & fees

Apr 2 - Apr 3

[](https://www.expedia.ca/Jacksonville-Hotels-The-Hotel-Palms.h15784631.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/2f9db172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/d12dee4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/18cf9eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/714d9afd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott® Jacksonville Mayport

[](https://www.expedia.ca/Jacksonville-Hotels-Towneplace-Suites-By-Marriott-Atlantic-Beach.h111923614.Hotel-Information)

10.8 km from Mayo Clinic Florida

9.8/10

Exceptional

(86 reviews)

"Loved the staff, the cleanliness, and the food was excellent. Really enjoyed my stay here!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Toni

CA $170

CA $193 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Jacksonville-Hotels-Towneplace-Suites-By-Marriott-Atlantic-Beach.h111923614.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/898b0a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/w3837h2560x3y3-801b9f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/c7b511f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/9b491ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)

4.2 km from Mayo Clinic Florida

9.0/10

Wonderful

(1,041 reviews)

"Great staff and Clean hotel "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tyniesha

CA $177

CA $201 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/30000/25400/25311/b5695ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach/ocean view](https://images.trvl-media.com/lodging/1000000/30000/25400/25311/3171b62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25400/25311/04198d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms](https://images.trvl-media.com/lodging/1000000/30000/25400/25311/842c9ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Lodge and Club at Ponte Vedra Beach

[](https://www.expedia.ca/Jacksonville-Hotels-The-Lodge-And-Club-At-Ponte-Vedra-Beach.h25311.Hotel-Information)

6.3 km from Mayo Clinic Florida

9.4/10

Exceptional

(689 reviews)

"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

CA $680

CA $798 total

includes taxes & fees

Apr 12 - Apr 13

[](https://www.expedia.ca/Jacksonville-Hotels-The-Lodge-And-Club-At-Ponte-Vedra-Beach.h25311.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/335b1fee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/fab1e174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/fba2ad11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/be234916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AC Hotel Jacksonville St Johns Town Center

[](https://www.expedia.ca/Jacksonville-Hotels-AC-Hotel-Jacksonville-ST-Johns-Town-CTR.h99777110.Hotel-Information)

Southside, 8.1 km from Mayo Clinic Florida

9.4/10

Exceptional

(181 reviews)

"Staff was excellent...highly recommend this Hotel"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Robert

CA $257

CA $292 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Jacksonville-Hotels-AC-Hotel-Jacksonville-ST-Johns-Town-CTR.h99777110.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/d30ef697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/97c5b971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/04850bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/512c8fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Margaritaville Jacksonville Beach

[](https://www.expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information)

5.9 km from Mayo Clinic Florida

9.0/10

Wonderful

(3,732 reviews)

"Nice spot, friendly staff, nice bar and great beach location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Keith

CA $231

CA $263 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information)

![Sports facility](https://images.trvl-media.com/lodging/30000000/29850000/29846500/29846486/130353e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/30000000/29850000/29846500/29846486/dfe7c0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/30000000/29850000/29846500/29846486/87c3aa17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/30000000/29850000/29846500/29846486/6ba7ab47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Place Jacksonville / St. Johns Town Center

[](https://www.expedia.ca/Jacksonville-Hotels-Hyatt-Place-Jacksonville-St-Johns-Town-Center.h29846486.Hotel-Information)

Southside, 8.6 km from Mayo Clinic Florida

9.2/10

Wonderful

(1,002 reviews)

"Everything was great"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Antonio

CA $155

CA $176 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Jacksonville-Hotels-Hyatt-Place-Jacksonville-St-Johns-Town-Center.h29846486.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/980000/975500/975423/7989c84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Balcony](https://images.trvl-media.com/lodging/1000000/980000/975500/975423/7555838e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/980000/975500/975423/7977b403.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/980000/975500/975423/4914098f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

[](https://www.expedia.ca/Jacksonville-Hotels-Hilton-Garden-Inn-Jacksonville-Ponte-Vedra-Sawgrass.h975423.Hotel-Information)

8.5 km from Mayo Clinic Florida

9.2/10

Wonderful

(1,013 reviews)

"Great stay all around "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeffrey

CA $214

CA $239 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Jacksonville-Hotels-Hilton-Garden-Inn-Jacksonville-Ponte-Vedra-Sawgrass.h975423.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1980000/1971500/1971479/d15a0cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (USD 18.00 per person)](https://images.trvl-media.com/lodging/2000000/1980000/1971500/1971479/200232f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/2000000/1980000/1971500/1971479/w4000h2663x0y0-91f7fa88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1980000/1971500/1971479/de0c0819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sheraton Jacksonville Hotel

[](https://www.expedia.ca/Jacksonville-Hotels-Sheraton-Jacksonville-Hotel.h1971479.Hotel-Information)

Deerwood, 9.6 km from Mayo Clinic Florida

9.2/10

Wonderful

(1,000 reviews)

"Beautiful property and great staff "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrew

CA $184

CA $209 total

includes taxes & fees

Apr 3 - Apr 4

[](https://www.expedia.ca/Jacksonville-Hotels-Sheraton-Jacksonville-Hotel.h1971479.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/ac80791a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/c5d5c944.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/a10175e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/10ecbce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Jacksonville Beach by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)

4.6 km from Mayo Clinic Florida

9.2/10

Wonderful

(1,000 reviews)

"Overall a very convenient and clean facility."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chuck

CA $178

CA $202 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/8cf3943d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/w3995h2667x0y0-516d4609.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, Multiple Beds, Balcony, Oceanfront](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/b29f7074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/c103e93e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Springhill Suites By Marriott Jacksonville Beach Oceanfront

[](https://www.expedia.ca/Jacksonville-Hotels-Springhill-Suites-By-Marriott-Jacksonville-Beach-Oceanfront.h90175988.Hotel-Information)

5.8 km from Mayo Clinic Florida

9.0/10

Wonderful

(648 reviews)

"Had an amazing getaway! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Meena

CA $266

CA $302 total

includes taxes & fees

Mar 22 - Mar 23

[](https://www.expedia.ca/Jacksonville-Hotels-Springhill-Suites-By-Marriott-Jacksonville-Beach-Oceanfront.h90175988.Hotel-Information)

![On the beach](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/cd4b0791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/3260d371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/105ea82f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/43c9ff41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Oceanfront

[](https://www.expedia.ca/Jacksonville-Hotels-Best-Western-Oceanfront.h119095.Hotel-Information)

5.7 km from Mayo Clinic Florida

9.0/10

Wonderful

(1,006 reviews)

"Great location, breakfast was delicious "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

CA $174

CA $198 total

includes taxes & fees

Apr 13 - Apr 14

[](https://www.expedia.ca/Jacksonville-Hotels-Best-Western-Oceanfront.h119095.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-27&endDate=2026-03-28&regionId=6127706&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Mayo Clinic Florida Hotel Reviews

![Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/0fcbe763_y.jpg)

### Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

8/10 Good

"Pool is not heated, but facilities are clean and staff is great."

[](https://expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)

![Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/b5b95b3d_y.jpg)

### Residence Inn By Marriott Jacksonville - Mayo Clinic Area

8/10 Good

"Good location to multiple attractions in the city. Love the free and easily accessible parking. "

[](https://expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)

![Margaritaville Jacksonville Beach](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/d30ef697_y.jpg)

### Margaritaville Jacksonville Beach

10/10 Excellent

"Excelent"

[](https://expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information)

![Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/9eef35fb_y.jpg)

### Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

8/10 Good

"Easy ro park room features were al working beds were comfortable"

[](https://expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Beach-BlvdMayo-Clinic.h2880174.Hotel-Information)

![New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach](https://images.trvl-media.com/lodging/118000000/117050000/117041900/117041879/2b1a86aa_y.jpg)

### New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach

10/10 Excellent

"Great host!!"

[](https://expedia.ca/Jacksonville-Hotels-New-2-Miles-2Mayo-Clinic-Intracoastal-Water-Views-Mins-To-JaxBeach.h117041879.Hotel-Information)

![Hilton Jacksonville At Mayo Clinic](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/b2da11bc_y.jpg)

### Hilton Jacksonville At Mayo Clinic

10/10 Excellent

"Very clean and room was nice "

[](https://expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information)

![Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/898b0a5a_y.jpg)

### Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

10/10 Excellent

"very nice"

[](https://expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)

![Peaceful Mayo Condo - 5 Min to Mayo, Pool & Gym, Beach & UNF Nearby](https://images.trvl-media.com/lodging/125000000/124220000/124216700/124216688/87c8c07e_y.jpg)

### Peaceful Mayo Condo - 5 Min to Mayo, Pool & Gym, Beach & UNF Nearby

10/10 Excellent

"Super clean and exactly like the pictures. Great communication from the owner. I will book again if I come to Jacksonville. "

[](https://expedia.ca/Jacksonville-Hotels-Peaceful-Mayo-Condo-5-Min-To-Clinic.h124216688.Hotel-Information)

![TownePlace Suites by Marriott Jacksonville East](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/3ebd8af1_y.jpg)

### TownePlace Suites by Marriott Jacksonville East

10/10 Excellent

"Very nice accommodation , clean , and comfortable"

[](https://expedia.ca/Jacksonville-Hotels-TownePlace-Suites-By-Marriott-Jacksonville-East.h50557569.Hotel-Information)

## Hotels near other Mayo Clinic Florida attractions

### Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6068663)

### Windsor Commons Shopping Center

You can enjoy retail therapy at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's acclaimed theater scene and great live music. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558033805)

### Harbor City Municipal Golf Course

Enjoy a round of golf in Jacksonville at Harbor City Municipal Golf Course. Amble around the area's beautiful beaches or attend a sporting event. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621563220206)

### Cradle Creek Preserve

Explore the great outdoors at Cradle Creek Preserve, a lovely green space in Jacksonville Beach. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621561766841)

### Jacksonville Beach Golf Club

3.9/5 (58 reviews)

Enjoy a round of golf in Jacksonville Beach at Jacksonville Beach Golf Club. Wander the beautiful beaches and seaside in this romantic area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621561766896)

### South Beach Park and Sunshine Playground

4.3/5 (44 reviews)

South Beach Park and Sunshine Playground is just one of the places to see in Jacksonville Beach, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or experience the acclaimed theater scene in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621561892262)

### Gonzales Park

4.1/5 (31 reviews)

Gonzales Park is just one of the places to see in Jacksonville Beach, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or experience the entertainment choices in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558033757)

### Pablo Plaza Shopping Center

You can search for that perfect souvenir at Pablo Plaza Shopping Center during your trip to Jacksonville Beach. Wander the beautiful beaches and seaside in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558033367)

## Frequently asked questions

### What are the top-rated hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area is situated within an 18-minute walking distance from Mayo Clinic Florida and has a solid review rating of 9.4\. This 3-star hotel provides travellers with a complimentary buffet breakfast each morning, alongside amenities such as an outdoor pool and a well-equipped fitness centre available 24/7\. The presence of a kitchen in every room, complete with a refrigerator and microwave, allows travellers to prepare meals at their convenience, enhancing their stay in Jacksonville.
> 
>   
> [Element Jacksonville Beach](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)
> 
>   
> Element Jacksonville Beach is a delightful 3-star hotel located just 8.0 km from Mayo Clinic Florida, with an impressive review rating of 9.6\. This hotel offers a variety of amenities including an outdoor pool, a fitness centre, and free breakfast—ideal for travellers looking for a refreshing stay. Unique features like a hydromassage showerhead and a fully equipped kitchen with a dishwasher and stovetop elevate the experience, making it a great choice for travellers seeking both relaxation and functionality.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Holiday Inn Express Jacksonville Beach by IHG is just 6.9 km from Mayo Clinic Florida, with an excellent review rating of 9.2\. This inviting hotel features an outdoor pool and offers a daily buffet breakfast to start the day right. Guests will appreciate the free internet access and the relaxing terrace, while the nearby a nearby beach adds an enjoyable outdoor experience to their visit.

### What hotels are within walking distance to Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area is a welcoming 3-star hotel just an 18-minute walk from Mayo Clinic Florida, rated 9.4 by travellers. Guests appreciate the spacious rooms featuring kitchen amenities such as a dishwasher and microwave, along with the convenience of free daily breakfast. The outdoor pool and 24-hour fitness centre provide great options for relaxation and exercise, while the garden area enhances the overall ambiance.
> 
>   
> [Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches](https://www.expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)
> 
>   
> Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches offers a prime location only 3 minutes from Mayo Clinic Florida, a review rating of 8.4\. This 3-star hotel features an outdoor pool and a well-equipped fitness centre, ensuring travellers have ample opportunities to unwind. With modern amenities like premium bedding and a snack bar, visitors can enjoy a comfortable stay close to their medical appointments.

### How much is a hotel near Mayo Clinic Florida?

### What are the most popular family-friendly hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area, rated 9.4 by travellers, is only an 18-minute walk from Mayo Clinic Florida. This 3-star hotel is designed with families in mind, offering spacious suites with kitchen facilities and free rollaway beds. Guests can take advantage of the outdoor pool, 24-hour fitness centre, and complimentary breakfast to start their day right.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Holiday Inn Express Jacksonville Beach by IHG offers a family-friendly experience just 6.9 km from Mayo Clinic Florida, with a great traveler rating score of 9.2\. Families will appreciate the free cribs, connecting rooms, and outdoor pool. Additional amenities include a complimentary breakfast served daily and easy access to the nearby beach, making it a great option for relaxation after a visit to the clinic.
> 
>   
> [Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)
> 
>   
> Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG is a family-friendly hotel located just 4.8 km from Mayo Clinic Florida. With a review rating of 8.4, this hotel features amenities such as free cribs, connecting rooms, and complimentary buffet breakfast, ensuring a comfortable stay for families. Guests can also enjoy an outdoor pool and easy access to nearby shopping and golf courses.

### Which hotels near Mayo Clinic Florida offer the best views?

> [Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)
> 
>   
> Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG is a welcoming 3-star hotel located just 4.8 km from Mayo Clinic Florida, rated 8.4 by travellers. This hotel features an outdoor pool with golf course views, perfect for relaxation after a day of appointments. Guests can enjoy a complimentary buffet breakfast daily, along with access to fitness facilities and free self-parking. A nearby shopping centre adds to the convenience, making it an ideal choice for those seeking both comfort and scenic views.

### What are the best affordable hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area is a 3-star hotel situated a short 18-minute walk from Mayo Clinic Florida, with a great traveler rating score of 9.4\. This hotel is perfect for families, offering free breakfast daily and a kitchen in each suite for convenient meal preparation. Additional amenities include an outdoor pool, 24-hour fitness facilities, and free self-parking, making it a practical choice for extended stays or quick visits alike.
> 
>   
> [Element Jacksonville Beach](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)
> 
>   
> Element Jacksonville Beach is a 3-star hotel located just 8.0 km from Mayo Clinic Florida, with an impressive review rating of 9.6\. This family-friendly hotel offers complimentary breakfast options, including a cooked breakfast and free WiFi, ensuring a pleasant start to your day. Guests can enjoy amenities such as an outdoor pool, fitness centre, and fully-equipped kitchens in select rooms, making it an ideal choice for those looking for a comfortable and affordable stay.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Holiday Inn Express Jacksonville Beach by IHG is located 6.9 km from Mayo Clinic Florida and has a solid review rating of 9.2\. This hotel provides a complimentary buffet breakfast and free WiFi, suiting families and budget-conscious travellers. Guests can also take advantage of the outdoor pool, free self-parking, and nearby beach access, ensuring a relaxing and enjoyable experience during their stay.

### Are there any hotels with pools close to Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Just an 18-minute walk from Mayo Clinic Florida, the 3-star Residence Inn By Marriott Jacksonville offers a fantastic outdoor pool equipped with sun loungers and a poolside bar, perfect for relaxation after a long day. Rated 9.4 by travellers, this hotel features free buffet breakfast, a fitness centre available 24/7, and spacious rooms complete with kitchen facilities, making it ideal for both short and extended stays.
> 
>   
> [Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)
> 
>   
> Located 5.6 km from Mayo Clinic Florida, the Hampton Inn features an inviting outdoor pool with accessible options and sun loungers, rated 8.8 by travellers. Guests can enjoy a complimentary breakfast daily and access to fitness facilities. With nearby beach access, this hotel offers a blend of relaxation and convenience, perfect for those needing nearby the clinic.
> 
>   
> [Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)
> 
>   
> Situated 4.8 km from Mayo Clinic Florida, the Holiday Inn Express boasts an outdoor pool surrounded by sun loungers and umbrellas, rated 8.4 by travellers. Guests can indulge in a free breakfast each morning and benefit from modern amenities including a fitness centre. This hotel is a great choice for those looking for comfort and convenience close to medical facilities.

### What are the best pet-friendly hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> The Residence Inn By Marriott Jacksonville - Mayo Clinic Area is just an 18-minute walk from Mayo Clinic Florida and boasts an impressive review rating of 9.4\. This 3-star hotel welcomes pets with amenities such as in-room pet accommodations and service animals. Guests can enjoy a complimentary buffet breakfast, an outdoor pool, and a well-equipped fitness centre, making it a great choice for travellers seeking comfort and convenience.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Located 6.9 km from Mayo Clinic Florida, the Holiday Inn Express Jacksonville Beach by IHG is a fantastic option for pet owners, rated 9.2 by travellers. This hotel allows pets and offers amenities like free breakfast and an outdoor pool. Guests will appreciate the nearby sandy beach, making it perfect for leisurely walks with their dogs after a day at the clinic.
> 
>   
> [Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)
> 
>   
> The Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area is a pet-friendly haven situated just 5.6 km from Mayo Clinic Florida, with a great traveler rating score of 8.8\. This hotel features in-room pet accommodations and a complimentary breakfast. Guests can unwind at the outdoor pool or explore the nearby beach, ensuring a pleasant stay for both pets and their owners.

### Can I book a fully refundable hotel close to Mayo Clinic Florida?

### Can I find Expedia discounts for hotels near Mayo Clinic Florida?

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- [Flights to Jacksonville Beach ](https://www.expedia.ca/Cheap-Flights-To-Jacksonville-Beach.d8196.Travel-Guide-Flights)
- [Flights from Ottawa to Jacksonville Beach ](https://www.expedia.ca/lp/flights/178296/8196/ottawa-to-jacksonville-beach)
- [Flights from Toronto to Jacksonville Beach ](https://www.expedia.ca/lp/flights/178314/8196/toronto-to-jacksonville-beach)

- [Adventure Landing ](https://www.expedia.ca/Adventure-Landing-Jacksonville.d6128080.Vacation-Attraction)
- [Visit Beach Cities Jacksonville ](https://www.expedia.ca/Beach-Cities-Jacksonville.dx6062930)
- [Jacksonville Beach Vacations ](https://www.expedia.ca/Jacksonville-Beach.d8196.Destination-Travel-Guides)
- [Visit Jacksonville Beach ](https://www.expedia.ca/Jacksonville-Beach.dx8196)
- [Visit Isle of Palms ](https://www.expedia.ca/Jacksonville-Isle-Of-Palms.dx553248635976480347)
- [Visit Sans Pareil ](https://www.expedia.ca/Jacksonville-Sans-Pareil.dx553248635975852002)

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- [Jacksonville Beach Vacation Rentals ](https://www.expedia.ca/Jacksonville-Beach-Vacation-Rentals.d8196.Travel-Guide-VacationRentals)

- [Things to do in Jacksonville Beach ](https://www.expedia.ca/Things-To-Do-In-Jacksonville-Beach.d8196.Travel-Guide-Activities)