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Our top choices for Mayo Clinic Florida hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (513 reviews)
The price is CA $191
CA $217 total
includes taxes & fees
May 29 - May 30

Hilton Jacksonville At Mayo Clinic
Hilton Jacksonville At Mayo Clinic0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (232 reviews)
The price is CA $225
CA $255 total
includes taxes & fees
May 29 - May 30

TownePlace Suites by Marriott Jacksonville East
TownePlace Suites by Marriott Jacksonville EastGolden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (614 reviews)
The price is CA $152
CA $172 total
includes taxes & fees
May 31 - Jun 1

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo ClinicGolden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,001 reviews)
The price is CA $146
CA $165 total
includes taxes & fees
May 31 - Jun 1

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,040 reviews)
The price is CA $131
CA $149 total
includes taxes & fees
May 24 - May 25

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (774 reviews)
The price is CA $209
CA $238 total
includes taxes & fees
May 30 - May 31

The Hotel Palms Poolside
The Hotel Palms Poolside7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (474 reviews)
The price is CA $248
CA $282 total
includes taxes & fees
May 31 - Jun 1

Element by Marriott Jacksonville Beach
Element by Marriott Jacksonville Beach5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (557 reviews)
The price is CA $209
CA $237 total
includes taxes & fees
Jun 14 - Jun 15

The Hotel Palms Courtyard
The Hotel Palms Courtyard7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (297 reviews)
The price is CA $256
CA $290 total
includes taxes & fees
Jun 7 - Jun 8

Holiday Inn Express Jacksonville Beach by IHG
Holiday Inn Express Jacksonville Beach by IHG4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,001 reviews)
The price is CA $180
CA $204 total
includes taxes & fees
Jun 14 - Jun 15

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,110 reviews)
The price is CA $169
CA $191 total
includes taxes & fees
Jun 21 - Jun 22

AC Hotel Jacksonville St Johns Town Center
AC Hotel Jacksonville St Johns Town CenterSouthside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (199 reviews)
The price is CA $221
CA $251 total
includes taxes & fees
May 29 - May 30

TownePlace Suites by Marriott® Jacksonville Mayport
TownePlace Suites by Marriott® Jacksonville Mayport10.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (102 reviews)
The price is CA $172
CA $195 total
includes taxes & fees
Jun 7 - Jun 8

Hyatt Place Jacksonville / St. Johns Town Center
Hyatt Place Jacksonville / St. Johns Town CenterSouthside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,025 reviews)
The price is CA $186
CA $211 total
includes taxes & fees
Jun 14 - Jun 15

Margaritaville Jacksonville Beach
Margaritaville Jacksonville Beach5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,973 reviews)
The price is CA $259
CA $294 total
includes taxes & fees
May 25 - May 26

Springhill Suites By Marriott Jacksonville Beach Oceanfront
Springhill Suites By Marriott Jacksonville Beach Oceanfront5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (696 reviews)
The price is CA $233
CA $264 total
includes taxes & fees
May 31 - Jun 1

Best Western Oceanfront
Best Western Oceanfront5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
The price is CA $206
CA $234 total
includes taxes & fees
Jun 7 - Jun 8

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,019 reviews)
The price is CA $181
CA $202 total
includes taxes & fees
Jun 21 - Jun 22

Hotel Indigo Jacksonville-Deerwood Park by IHG
Hotel Indigo Jacksonville-Deerwood Park by IHGSouthside, 10.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (1,000 reviews)
The price is CA $168
CA $190 total
includes taxes & fees
May 25 - May 26

Four Points by Sheraton Jacksonville Beachfront
Four Points by Sheraton Jacksonville Beachfront5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,009 reviews)
The price is CA $291
CA $330 total
includes taxes & fees
Jun 14 - Jun 15
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Mayo Clinic Florida
Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Residence Inn By Marriott Jacksonville - Mayo Clinic Area | 9.4 Exceptional 513 reviews | View | ||||||
![]() Hilton Jacksonville At Mayo Clinic | 9.4 Exceptional 232 reviews | View | ||||||
![]() TownePlace Suites by Marriott Jacksonville East | 9.2 Wonderful 614 reviews | View | ||||||
![]() Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic | 9.0 Wonderful 1,001 reviews | View | ||||||
![]() Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG | 8.8 Excellent 1,040 reviews | View |
Top Mayo Clinic Florida Hotel Reviews

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
10/10 Excellent
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