Title: The 10 Best Hotels Near Mayo Clinic Florida, Jacksonville from CA $140 | Expedia.ca

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# Find hotels near Mayo Clinic Florida, Jacksonville from CA $140

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## Check prices for these dates

Tonight

[Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6127706&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Mayo Clinic Florida hotels

![Lobby](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/b5b95b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/c8f0b79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/5b1f404a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/8626ba46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn By Marriott Jacksonville - Mayo Clinic Area

[](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)

1.1 km from Mayo Clinic Florida

9.4/10

Exceptional

(446)

"Great facility to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gary

CA $205

CA $233 total

includes taxes & fees

Dec 19 - Dec 20

[](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/b2da11bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lake view](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/1e6ff5e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/c1792edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/d0436ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Jacksonville At Mayo Clinic

[](https://www.expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information)

0.8 km from Mayo Clinic Florida

9.2/10

Wonderful

(53)

"Beautiful hotel. Close to Mayo Clinic."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Patty

CA $168

CA $191 total

includes taxes & fees

Dec 20 - Dec 21

[](https://www.expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/3ebd8af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/bb7e3270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/a7e8a27c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/a0b6a0da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Jacksonville East

[](https://www.expedia.ca/Jacksonville-Hotels-TownePlace-Suites-By-Marriott-Jacksonville-East.h50557569.Hotel-Information)

Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida

9.2/10

Wonderful

(546)

"Very good hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Careli

CA $157

CA $178 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Jacksonville-Hotels-TownePlace-Suites-By-Marriott-Jacksonville-East.h50557569.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/9eef35fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/6d3a7b4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/1bf84034.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/1ba0722a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Beach-BlvdMayo-Clinic.h2880174.Hotel-Information)

Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida

9.0/10

Wonderful

(1003)

"very clean room, great staff, very quiet and a variety of breakfast options."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joy

CA $131

CA $149 total

includes taxes & fees

Dec 19 - Dec 20

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Beach-BlvdMayo-Clinic.h2880174.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/0fcbe763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/620f795f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/1373ce48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/0036a1dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)

2.7 km from Mayo Clinic Florida

8.6/10

Excellent

(1006)

"Good location for a family vacation "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angel

CA $145

CA $164 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/7dde0660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/3cb87b81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/36a2496a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/ae56473a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

[](https://www.expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)

0.3 km from Mayo Clinic Florida

8.4/10

Very good

(751)

"Nice hotel, close to shops and mayo clinic."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy

CA $222

CA $252 total

includes taxes & fees

Dec 26 - Dec 27

[](https://www.expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/2f9db172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/d12dee4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/2ef5c205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/112000000/111930000/111923700/111923614/18cf9eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott® Jacksonville Mayport

[](https://www.expedia.ca/Jacksonville-Hotels-Towneplace-Suites-By-Marriott-Atlantic-Beach.h111923614.Hotel-Information)

10.8 km from Mayo Clinic Florida

9.8/10

Exceptional

(64)

"This was an awesome place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christine

CA $160

CA $181 total

includes taxes & fees

Dec 18 - Dec 19

[](https://www.expedia.ca/Jacksonville-Hotels-Towneplace-Suites-By-Marriott-Atlantic-Beach.h111923614.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/322c81fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/w5565h3712x0y0-2f0fd935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/3cc0c712.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/68000000/67400000/67391300/67391288/5d3207b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Element Jacksonville Beach

[](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)

5.4 km from Mayo Clinic Florida

9.6/10

Exceptional

(521)

"The hotel was spotless as usual.The staff was fantastic incredible cleanliness"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

CA $163

CA $185 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/3cc4947f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/36e9c181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/dffb8ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/35000000/34420000/34413500/34413457/a435d2ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Jacksonville - Town Center by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-Town-Center.h34413457.Hotel-Information)

Southside, 7.8 km from Mayo Clinic Florida

9.6/10

Exceptional

(1002)

"Nice refurbished rooms.. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

CA $183

CA $208 total

includes taxes & fees

Dec 24 - Dec 25

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-Town-Center.h34413457.Hotel-Information)

![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/b159421b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 Queen Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/fcfa2192.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/fe355a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/16000000/15790000/15784700/15784631/c2598c1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Hotel Palms

[](https://www.expedia.ca/Jacksonville-Hotels-The-Hotel-Palms.h15784631.Hotel-Information)

7.8 km from Mayo Clinic Florida

9.6/10

Exceptional

(291)

"stayed here for an event and it was awesome"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

clayton

CA $233

CA $264 total

includes taxes & fees

Jan 6 - Jan 7, 2026

[](https://www.expedia.ca/Jacksonville-Hotels-The-Hotel-Palms.h15784631.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/335b1fee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/w4000h2663x0y4-b90721a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/5740568d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99780000/99777200/99777110/fba2ad11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AC Hotel Jacksonville St Johns Town Center

[](https://www.expedia.ca/Jacksonville-Hotels-AC-Hotel-Jacksonville-ST-Johns-Town-CTR.h99777110.Hotel-Information)

Southside, 8.1 km from Mayo Clinic Florida

9.4/10

Exceptional

(163)

"Staff was excellent...highly recommend this Hotel"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Robert

CA $226

CA $256 total

includes taxes & fees

Dec 19 - Dec 20

[](https://www.expedia.ca/Jacksonville-Hotels-AC-Hotel-Jacksonville-ST-Johns-Town-CTR.h99777110.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1093000/1092930/aac35dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1100000/1093000/1092930/d1b89cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1100000/1093000/1092930/b2bb9bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room | Minibar](https://images.trvl-media.com/lodging/2000000/1100000/1093000/1092930/764fa1da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Jacksonville Deerwood Park

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Deerwood-Park.h1092930.Hotel-Information)

Southside, 11.2 km from Mayo Clinic Florida

9.4/10

Exceptional

(1002)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary Jean

CA $126

CA $143 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Deerwood-Park.h1092930.Hotel-Information)

![Sports facility](https://images.trvl-media.com/lodging/30000000/29850000/29846500/29846486/130353e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/30000000/29850000/29846500/29846486/dfe7c0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/30000000/29850000/29846500/29846486/0dae47f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/30000000/29850000/29846500/29846486/87c3aa17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Place Jacksonville / St. Johns Town Center

[](https://www.expedia.ca/Jacksonville-Hotels-Hyatt-Place-Jacksonville-St-Johns-Town-Center.h29846486.Hotel-Information)

Southside, 8.6 km from Mayo Clinic Florida

9.2/10

Wonderful

(1000)

"Good location, friendly staff, clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

john

CA $164

CA $186 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Jacksonville-Hotels-Hyatt-Place-Jacksonville-St-Johns-Town-Center.h29846486.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1980000/1971500/1971479/d15a0cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and dinner served, garden views ](https://images.trvl-media.com/lodging/2000000/1980000/1971500/1971479/f2b64ced.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/2000000/1980000/1971500/1971479/w4000h2663x0y0-91f7fa88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1980000/1971500/1971479/de0c0819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sheraton Jacksonville Hotel

[](https://www.expedia.ca/Jacksonville-Hotels-Sheraton-Jacksonville-Hotel.h1971479.Hotel-Information)

Deerwood, 9.6 km from Mayo Clinic Florida

9.2/10

Wonderful

(1001)

"Great stay and great customer service"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rebecca

CA $123

CA $140 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Jacksonville-Hotels-Sheraton-Jacksonville-Hotel.h1971479.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2392300/2392277/w6716h4480x0y0-c9dc526d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2392300/2392277/b08f67f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/3000000/2400000/2392300/2392277/6c804579.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/3000000/2400000/2392300/2392277/c8ff6767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Indigo Jacksonville-Deerwood Park by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Hotel-Indigo-Jacksonville-Deerwood-Park.h2392277.Hotel-Information)

Southside, 10.8 km from Mayo Clinic Florida

9.2/10

Wonderful

(1001)

"Very nice stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Timmothy

CA $163

CA $185 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Jacksonville-Hotels-Hotel-Indigo-Jacksonville-Deerwood-Park.h2392277.Hotel-Information)

![On the beach](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/cd4b0791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/b0d3d74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/105ea82f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/120000/119100/119095/43c9ff41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Oceanfront

[](https://www.expedia.ca/Jacksonville-Hotels-Best-Western-Oceanfront.h119095.Hotel-Information)

5.7 km from Mayo Clinic Florida

9.0/10

Wonderful

(1006)

"The room was clean and the bed was very comfortable! The view was beautiful! I will definitely stay here again in the future "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tinya

CA $170

CA $193 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Jacksonville-Hotels-Best-Western-Oceanfront.h119095.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/d30ef697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/97c5b971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/512c8fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/04850bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Margaritaville Jacksonville Beach

[](https://www.expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information)

5.9 km from Mayo Clinic Florida

9.0/10

Wonderful

(3426)

"Excellent location & property "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Doris

CA $197

CA $224 total

includes taxes & fees

Dec 15 - Dec 16

[](https://www.expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/892900/892823/24c987fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/900000/892900/892823/0f56a79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Brewpub, beach views, open daily](https://images.trvl-media.com/lodging/1000000/900000/892900/892823/779495e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/900000/892900/892823/bd75f975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Points by Sheraton Jacksonville Beachfront

[](https://www.expedia.ca/Jacksonville-Hotels-Four-Points-By-Sheraton-Jacksonville-Beachfront.h892823.Hotel-Information)

5.6 km from Mayo Clinic Florida

9.0/10

Wonderful

(1002)

"Easy to walk to the beach and local restaurant"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Allen D

CA $245

CA $279 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Jacksonville-Hotels-Four-Points-By-Sheraton-Jacksonville-Beachfront.h892823.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/ac80791a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/10ecbce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/a10175e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/c5d5c944.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Jacksonville Beach by IHG

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)

4.6 km from Mayo Clinic Florida

9.2/10

Wonderful

(1001)

"Overall very nice and comfortable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maria

CA $158

CA $180 total

includes taxes & fees

Dec 18 - Dec 19

[](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/8cf3943d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 2 Queen Beds, Balcony, Oceanfront](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/b29f7074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/76bd5c14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/91000000/90180000/90176000/90175988/c103e93e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Springhill Suites By Marriott Jacksonville Beach Oceanfront

[](https://www.expedia.ca/Jacksonville-Hotels-Springhill-Suites-By-Marriott-Jacksonville-Beach-Oceanfront.h90175988.Hotel-Information)

5.8 km from Mayo Clinic Florida

9.0/10

Wonderful

(619)

"Loved staying here. Great hotel. Very clean. The check-in process was smooth and Jay was awesome. I would recommend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kedric

CA $209

CA $238 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Jacksonville-Hotels-Springhill-Suites-By-Marriott-Jacksonville-Beach-Oceanfront.h90175988.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27&regionId=6127706&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Mayo Clinic Florida Hotel Reviews

![Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/5b1f404a_y.jpg)

### Residence Inn By Marriott Jacksonville - Mayo Clinic Area

10/10 Excellent

"Clean, convenient to interstate, Mayo Hospital, 10 minutes from numerous restaurants and shopping. The staff was friendly. "

[](https://expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)

![Margaritaville Jacksonville Beach](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/863d9eb6_y.jpg)

### Margaritaville Jacksonville Beach

10/10 Excellent

"Room overlooked the water and was an amazing sunrise "

[](https://expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information)

![Hilton Jacksonville At Mayo Clinic](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/a30920c9_y.jpg)

### Hilton Jacksonville At Mayo Clinic

10/10 Excellent

"Room with spotless. Staff was courteous. The amenities excellent."

[](https://expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information)

![Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://images.trvl-media.com/lodging/1000000/900000/898100/898066/0fcbe763_y.jpg)

### Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

10/10 Excellent

"Our room was clean and comfortable. The breakfast was excellent; lots of choices with quality food. Our stay was very pleasant and will definitely stay again next year."

[](https://expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)

![Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/580000/570500/570425/w3837h2560x3y3-801b9f38_y.jpg)

### Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

10/10 Excellent

"Breakfast OK. Staff very good. Very clean and new carpet & walls. Room was nice and clean & good firm beds. Looks brand new. A bit hard to drive out with continual traffic. Would stay here again."

[](https://expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)

![Holiday Inn Express Jacksonville Beach by IHG](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818369/ac80791a_y.jpg)

### Holiday Inn Express Jacksonville Beach by IHG

10/10 Excellent

"Yes"

[](https://expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)

![Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic](https://images.trvl-media.com/lodging/3000000/2890000/2880200/2880174/7227c750_y.jpg)

### Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

10/10 Excellent

"Staff was super friendly and professional...rooms super clean and comfy"

[](https://expedia.ca/Jacksonville-Hotels-Hampton-Inn-Suites-Jacksonville-Beach-BlvdMayo-Clinic.h2880174.Hotel-Information)

![Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/7dde0660_y.jpg)

### Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

10/10 Excellent

"Clean and continent to mayo"

[](https://expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)

![TownePlace Suites by Marriott Jacksonville East](https://images.trvl-media.com/lodging/51000000/50560000/50557600/50557569/ce542e1c_y.jpg)

### TownePlace Suites by Marriott Jacksonville East

10/10 Excellent

"Both staff and room was awesome! It’s my second time staying. Will be back"

[](https://expedia.ca/Jacksonville-Hotels-TownePlace-Suites-By-Marriott-Jacksonville-East.h50557569.Hotel-Information)

## Hotels near other Mayo Clinic Florida attractions

### Adventure Landing

4.1/5 (157 reviews)

This amusement park east of Jacksonville is a fun daytrip for the whole family with thrilling rides, exciting attractions for kids and a shipwreck-themed waterpark.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6128080)

### Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6068663)

### Windsor Commons Shopping Center

You can enjoy retail therapy at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's great live music and entertainment choices. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558033805)

### Harbor City Municipal Golf Course

Enjoy a round of golf in Jacksonville at Harbor City Municipal Golf Course. Amble around the area's beautiful beaches or attend a sporting event. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621563220206)

### Cradle Creek Preserve

Explore the great outdoors at Cradle Creek Preserve, a lovely green space in Jacksonville Beach. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621561766841)

### Jacksonville Beach Golf Club

3.9/5 (58 reviews)

Enjoy a round of golf in Jacksonville Beach at Jacksonville Beach Golf Club. Wander the beautiful beaches and seaside in this romantic area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621561766896)

### South Beach Park and Sunshine Playground

4.3/5 (44 reviews)

South Beach Park and Sunshine Playground is just one of the places to see in Jacksonville Beach, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or experience the acclaimed theater scene in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621561892262)

### Gonzales Park

4.1/5 (31 reviews)

Gonzales Park is just one of the places to see in Jacksonville Beach, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or experience the entertainment choices in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558033757)

## Frequently asked questions

### What are the top-rated hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area is situated within an 18-minute walking distance from Mayo Clinic Florida and has a solid review rating of 9.4\. This 3-star hotel provides travellers with a complimentary buffet breakfast each morning, alongside amenities such as an outdoor pool and a well-equipped fitness centre available 24/7\. The presence of a kitchen in every room, complete with a refrigerator and microwave, allows travellers to prepare meals at their convenience, enhancing their stay in Jacksonville.
> 
>   
> [Element Jacksonville Beach](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)
> 
>   
> Element Jacksonville Beach is a delightful 3-star hotel located just 8.0 km from Mayo Clinic Florida, with an impressive review rating of 9.6\. This hotel offers a variety of amenities including an outdoor pool, a fitness centre, and free breakfast—ideal for travellers looking for a refreshing stay. Unique features like a hydromassage showerhead and a fully equipped kitchen with a dishwasher and stovetop elevate the experience, making it a great choice for travellers seeking both relaxation and functionality.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Holiday Inn Express Jacksonville Beach by IHG is just 6.9 km from Mayo Clinic Florida, with an excellent review rating of 9.2\. This inviting hotel features an outdoor pool and offers a daily buffet breakfast to start the day right. Guests will appreciate the free internet access and the relaxing terrace, while the nearby a nearby beach adds an enjoyable outdoor experience to their visit.

### What hotels are within walking distance to Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area is a welcoming 3-star hotel just an 18-minute walk from Mayo Clinic Florida, rated 9.4 by travellers. Guests appreciate the spacious rooms featuring kitchen amenities such as a dishwasher and microwave, along with the convenience of free daily breakfast. The outdoor pool and 24-hour fitness centre provide great options for relaxation and exercise, while the garden area enhances the overall ambiance.
> 
>   
> [Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches](https://www.expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information)
> 
>   
> Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches offers a prime location only 3 minutes from Mayo Clinic Florida, a review rating of 8.4\. This 3-star hotel features an outdoor pool and a well-equipped fitness centre, ensuring travellers have ample opportunities to unwind. With modern amenities like premium bedding and a snack bar, visitors can enjoy a comfortable stay close to their medical appointments.

### How much is a hotel near Mayo Clinic Florida?

### What are the most popular family-friendly hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area, rated 9.4 by travellers, is only an 18-minute walk from Mayo Clinic Florida. This 3-star hotel is designed with families in mind, offering spacious suites with kitchen facilities and free rollaway beds. Guests can take advantage of the outdoor pool, 24-hour fitness centre, and complimentary breakfast to start their day right.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Holiday Inn Express Jacksonville Beach by IHG offers a family-friendly experience just 6.9 km from Mayo Clinic Florida, with a great traveler rating score of 9.2\. Families will appreciate the free cribs, connecting rooms, and outdoor pool. Additional amenities include a complimentary breakfast served daily and easy access to the nearby beach, making it a great option for relaxation after a visit to the clinic.
> 
>   
> [Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)
> 
>   
> Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG is a family-friendly hotel located just 4.8 km from Mayo Clinic Florida. With a review rating of 8.4, this hotel features amenities such as free cribs, connecting rooms, and complimentary buffet breakfast, ensuring a comfortable stay for families. Guests can also enjoy an outdoor pool and easy access to nearby shopping and golf courses.

### Which hotels near Mayo Clinic Florida offer the best views?

> [Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)
> 
>   
> Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG is a welcoming 3-star hotel located just 4.8 km from Mayo Clinic Florida, rated 8.4 by travellers. This hotel features an outdoor pool with golf course views, perfect for relaxation after a day of appointments. Guests can enjoy a complimentary buffet breakfast daily, along with access to fitness facilities and free self-parking. A nearby shopping centre adds to the convenience, making it an ideal choice for those seeking both comfort and scenic views.

### What are the best affordable hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Residence Inn By Marriott Jacksonville - Mayo Clinic Area is a 3-star hotel situated a short 18-minute walk from Mayo Clinic Florida, with a great traveler rating score of 9.4\. This hotel is perfect for families, offering free breakfast daily and a kitchen in each suite for convenient meal preparation. Additional amenities include an outdoor pool, 24-hour fitness facilities, and free self-parking, making it a practical choice for extended stays or quick visits alike.
> 
>   
> [Element Jacksonville Beach](https://www.expedia.ca/Jacksonville-Hotels-Element-Jacksonville-Beach.h67391288.Hotel-Information)
> 
>   
> Element Jacksonville Beach is a 3-star hotel located just 8.0 km from Mayo Clinic Florida, with an impressive review rating of 9.6\. This family-friendly hotel offers complimentary breakfast options, including a cooked breakfast and free WiFi, ensuring a pleasant start to your day. Guests can enjoy amenities such as an outdoor pool, fitness centre, and fully-equipped kitchens in select rooms, making it an ideal choice for those looking for a comfortable and affordable stay.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Holiday Inn Express Jacksonville Beach by IHG is located 6.9 km from Mayo Clinic Florida and has a solid review rating of 9.2\. This hotel provides a complimentary buffet breakfast and free WiFi, suiting families and budget-conscious travellers. Guests can also take advantage of the outdoor pool, free self-parking, and nearby beach access, ensuring a relaxing and enjoyable experience during their stay.

### Are there any hotels with pools close to Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> Just an 18-minute walk from Mayo Clinic Florida, the 3-star Residence Inn By Marriott Jacksonville offers a fantastic outdoor pool equipped with sun loungers and a poolside bar, perfect for relaxation after a long day. Rated 9.4 by travellers, this hotel features free buffet breakfast, a fitness centre available 24/7, and spacious rooms complete with kitchen facilities, making it ideal for both short and extended stays.
> 
>   
> [Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)
> 
>   
> Located 5.6 km from Mayo Clinic Florida, the Hampton Inn features an inviting outdoor pool with accessible options and sun loungers, rated 8.8 by travellers. Guests can enjoy a complimentary breakfast daily and access to fitness facilities. With nearby beach access, this hotel offers a blend of relaxation and convenience, perfect for those needing nearby the clinic.
> 
>   
> [Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Suites-Jacksonville-SE-Med-Ctr-Area.h898066.Hotel-Information)
> 
>   
> Situated 4.8 km from Mayo Clinic Florida, the Holiday Inn Express boasts an outdoor pool surrounded by sun loungers and umbrellas, rated 8.4 by travellers. Guests can indulge in a free breakfast each morning and benefit from modern amenities including a fitness centre. This hotel is a great choice for those looking for comfort and convenience close to medical facilities.

### What are the best pet-friendly hotels near Mayo Clinic Florida?

> [Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information)
> 
>   
> The Residence Inn By Marriott Jacksonville - Mayo Clinic Area is just an 18-minute walk from Mayo Clinic Florida and boasts an impressive review rating of 9.4\. This 3-star hotel welcomes pets with amenities such as in-room pet accommodations and service animals. Guests can enjoy a complimentary buffet breakfast, an outdoor pool, and a well-equipped fitness centre, making it a great choice for travellers seeking comfort and convenience.
> 
>   
> [Holiday Inn Express Jacksonville Beach by IHG](https://www.expedia.ca/Jacksonville-Hotels-Holiday-Inn-Express-Jacksonville-Beach.h1818369.Hotel-Information)
> 
>   
> Located 6.9 km from Mayo Clinic Florida, the Holiday Inn Express Jacksonville Beach by IHG is a fantastic option for pet owners, rated 9.2 by travellers. This hotel allows pets and offers amenities like free breakfast and an outdoor pool. Guests will appreciate the nearby sandy beach, making it perfect for leisurely walks with their dogs after a day at the clinic.
> 
>   
> [Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area](https://www.expedia.ca/Jacksonville-Hotels-Hampton-Inn-JacksonvillePonte-Vedra-Beach-Mayo-Clinic-Area.h570425.Hotel-Information)
> 
>   
> The Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area is a pet-friendly haven situated just 5.6 km from Mayo Clinic Florida, with a great traveler rating score of 8.8\. This hotel features in-room pet accommodations and a complimentary breakfast. Guests can unwind at the outdoor pool or explore the nearby beach, ensuring a pleasant stay for both pets and their owners.

### Can I book a fully refundable hotel close to Mayo Clinic Florida?

### Can I find Expedia discounts for hotels near Mayo Clinic Florida?

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- [Hotels near University of North Florida ](https://www.expedia.ca/University-Of-North-Florida-Hotels.0-l6127797-0.Travel-Guide-Filter-Hotels)

- [Flights to Jacksonville Beach ](https://www.expedia.ca/Cheap-Flights-To-Jacksonville-Beach.d8196.Travel-Guide-Flights)
- [Flights from Ottawa to Jacksonville Beach ](https://www.expedia.ca/lp/flights/178296/8196/ottawa-to-jacksonville-beach)
- [Flights from Toronto to Jacksonville Beach ](https://www.expedia.ca/lp/flights/178314/8196/toronto-to-jacksonville-beach)

- [Adventure Landing ](https://www.expedia.ca/Adventure-Landing-Jacksonville.d6128080.Vacation-Attraction)
- [Visit Beach Cities Jacksonville ](https://www.expedia.ca/Beach-Cities-Jacksonville.dx6062930)
- [Jacksonville Beach Vacations ](https://www.expedia.ca/Jacksonville-Beach.d8196.Destination-Travel-Guides)
- [Visit Jacksonville Beach ](https://www.expedia.ca/Jacksonville-Beach.dx8196)
- [Visit Isle of Palms ](https://www.expedia.ca/Jacksonville-Isle-Of-Palms.dx553248635976480347)
- [Visit Sans Pareil ](https://www.expedia.ca/Jacksonville-Sans-Pareil.dx553248635975852002)

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- [Jacksonville Beach Vacation Rentals ](https://www.expedia.ca/Jacksonville-Beach-Vacation-Rentals.d8196.Travel-Guide-VacationRentals)

- [Things to do in Jacksonville Beach ](https://www.expedia.ca/Things-To-Do-In-Jacksonville-Beach.d8196.Travel-Guide-Activities)