Top Trending Hotels Near Mayo Clinic Florida, Southeast Jacksonville

See all 98 Hotels in Mayo Clinic Florida
Golden Star Beach House by RedAwning
Golden Star Beach House by RedAwning
5.5 km from Mayo Clinic Florida
3.0 out of 5.0

Located in Beach Cities, this vacation home is within a 15-minute walk of Freebird Live, Beaches Museum & History Park, and …

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Four Points by Sheraton Jacksonville Beachfront
Four Points by Sheraton Jacksonville Beachfront
5.6 km from Mayo Clinic Florida
3.0 out of 5.0
4.5 out of 5 (432 reviews)

Located in Beach Cities, this beachfront hotel is in the city center and within 2 mi (3 km) of Jacksonville Beach Pier and …

C$257
Best Western Oceanfront
Best Western Oceanfront
5.7 km from Mayo Clinic Florida
2.5 out of 5.0
4 out of 5 (1,009 reviews)

Located in Beach Cities, this beachfront resort is in the city center and within a 5-minute walk of Freebird Live, …

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Courtyard by Marriott Jacksonville Beach Oceanfront
Courtyard by Marriott Jacksonville Beach Oceanfront
6.3 km from Mayo Clinic Florida
3.0 out of 5.0
4.4 out of 5 (397 reviews)

Nestled on the beach, this Beach Cities resort is within 1 mi (2 km) of Jacksonville Beach Pier, J. Johnson Gallery, and …

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Marble Waters Hotel & Suites
Marble Waters Hotel & Suites
7.9 km from Mayo Clinic Florida
3.0 out of 5.0
3.7 out of 5 (1,675 reviews)

Situated near the airport, this hotel is within 6 mi (10 km) of Wilson Center For the Arts, University of North Florida, an …

C$112
Hampton Inn Jacksonville I-295 East/Baymeadows
Hampton Inn Jacksonville I-295 East/Baymeadows
8.9 km from Mayo Clinic Florida
2.5 out of 5.0
4.6 out of 5 (574 reviews)

Located in Southeast Jacksonville, this hotel is within 6 mi (10 km) of St. Johns Town Center, University of North Florida, …

C$125
Residence Inn by Marriott Jacksonville Butler Boulevard
Residence Inn by Marriott Jacksonville Butler Boulevard
9.9 km from Mayo Clinic Florida
3.0 out of 5.0
4.3 out of 5 (186 reviews)

Located in Southeast Jacksonville, this hotel is 1.5 mi (2.3 km) from St. Johns Town Center and 2.9 mi (4.7 km) from Morocc …

C$133
Aloft Jacksonville Tapestry Park
Aloft Jacksonville Tapestry Park
11 km from Mayo Clinic Florida
3.0 out of 5.0
4.4 out of 5 (702 reviews)

Located in Southeast Jacksonville, this hotel is within 3 mi (5 km) of St. Johns Town Center, Saint Vincent's Medical Cente …

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Extended Stay America - Jacksonville - Deerwood Park
Extended Stay America - Jacksonville - Deerwood Park
11 km from Mayo Clinic Florida
2.5 out of 5.0
3.1 out of 5 (346 reviews)

Located in Southeast Jacksonville, this hotel is within 3 mi (5 km) of St. Johns Town Center, Saint Vincent's Medical Cente …

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Ramada Jacksonville / Baymeadows Hotel & Conference Center
Ramada Jacksonville / Baymeadows Hotel & Conference Center
13 km from Mayo Clinic Florida
3.0 out of 5.0
3.7 out of 5 (625 reviews)

Located in Southeast Jacksonville, this hotel is within 6 mi (10 km) of Saint Vincent's Medical Center Southside, The Avenues …

C$99

Mayo Clinic Florida Hotel Guide

Explore the sights, discover the sounds, and immerse yourself in the city’s atmosphere: When you book a vacation at the top hotels near Mayo Clinic Florida, you’ll be in the best place to do it all. These properties are renowned for their central locations and comforting amenities, and the range of options lets you personalize your getaway to suit your travelling style.

Book a stay at one of the luxury hotels close to Mayo Clinic Florida to enjoy the first-class restaurants and spas, or grab one of the Mayo Clinic Florida hotel deals, if you want to save a few dollars on an inexpensive trip. Who knows? When you book with Expedia.ca, you might even find sale rates and deep discounts on the most popular Mayo Clinic Florida hotel.

Whether you’re heading out on a business trip or taking your family on yearly holiday, tracking down a cheap deal on Mayo Clinic Florida hotels in Southeast Jacksonville gives you the opportunity to wander around the local attractions without sacrificing your budget.