When is the best time to go to Main South?

The best time to visit Main South is during the autumn months, specifically from September to November, for pleasant weather and beautiful foliage. During this period, the temperatures are mild and comfortable, making it ideal for exploring the area on foot. You'll avoid the heat and humidity of summer and the colder, sometimes snowy, conditions of winter. The highlight of autumn is the spectacular display of fall colours, with trees ablaze in reds, oranges, and yellows throughout the region. Couples looking for a relaxed getaway will appreciate the serene beauty of Main South in the autumn. It's a lovely time for scenic drives through the surrounding countryside and visiting local orchards or farms. You can enjoy strolls through areas like the Elm Park, taking in the picturesque scenery. For solo travellers, the autumn offers a comfortable and inviting atmosphere for discovering the local history and culture without the larger crowds associated with peak summer travel.

Can I cancel my hotel reservation on Expedia?

Many Expedia hotel reservations are refundable, provided that you cancel before the hotel’s cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Main South hotel for you.

How much is the nightly rate at a Main South hotel?

Hotel prices in Main South often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

10 Best Hotels in Main South, Worcester for 2026

An aerial view of a city with a prominent building labeled "ART" and a church with a green spire.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Main South hotels

A modern lounge area with a stone wall, a fireplace, and a seating arrangement including sofas and a coffee table.

1. Homewood Suites By Hilton Worcester

Worcester Central Business District, 2.5 km from Main South

Nicole

CA $252 total

includes taxes & fees

Nov 5 - Nov 6

A dining area with a central island featuring a fruit bowl and a salad.

2. Hilton Garden Inn Worcester

Worcester Central Business District, 2.5 km from Main South

Thomas

CA $227 total

includes taxes & fees

Oct 22 - Oct 23

A modern lounge area with sofas, armchairs, a bar, and a fireplace.

3. Courtyard by Marriott Worcester

3.1 km from Main South

Dominic

CA $247 total

includes taxes & fees

Oct 29 - Oct 30

An outdoor seating area with wicker furniture and blue cushions, string lights overhead, and a fire feature in the center.

4. Hampton Inn & Suites Worcester

3.2 km from Main South

Carlo

CA $254 total

includes taxes & fees

Oct 18 - Oct 19

A modern living room with a fireplace, comfortable seating, and a large window.

5. AC Hotel by Marriott Worcester

Worcester Central Business District, 2.1 km from Main South

Matthew

CA $278 total

includes taxes & fees

Nov 6 - Nov 7

A grocery store with shelves stocked with various snacks and cereals.

6. enVision Hotel Worcester Downtown

Worcester Central Business District, 2.7 km from Main South

Christine

CA $196 total

includes taxes & fees

Oct 18 - Oct 19

A hotel lobby with multiple seating areas, including sofas and tables, and a bar area with a television.

7. Holiday Inn Express Hotel & Suites Auburn by IHG

6.9 km from Main South

John Patrick David

CA $154 total

includes taxes & fees

Nov 1 - Nov 2

A hotel entrance with a covered walkway, a parking area, and a well-lit building facade.

8. Hampton Inn Auburn

8.1 km from Main South

Diane

CA $160 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, pillows, a nightstand with a lamp, and a power outlet.

9. La Quinta Inn by Wyndham Auburn Worcester

5.9 km from Main South

Theresa

CA $139 total

includes taxes & fees

Nov 1 - Nov 2

A cozy living room with a fireplace, wooden bookshelves, and comfortable seating.

10. Comfort Inn Auburn - Worcester

5.7 km from Main South

Toby

CA $134 total

includes taxes & fees

Oct 29 - Oct 30

A Fairfield Inn & Suites by Marriott hotel with a covered entrance and landscaped surroundings.

11. Fairfield Inn & Suites by Marriott Worcester Auburn

8.2 km from Main South

Jeanne

CA $157 total

includes taxes & fees

Oct 18 - Oct 19

A pool table with billiard balls, a fireplace, and a dining area with chairs and a table.

12. Residence Inn by Marriott Worcester

6 km from Main South

Ulises

CA $277 total

includes taxes & fees

Nov 2 - Nov 3

A hotel with a patio area featuring outdoor seating and a garden with blue hydrangea flowers.

13. Beechwood Hotel

5.1 km from Main South

Wayne

CA $354 total

includes taxes & fees

Nov 6 - Nov 7

A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.

14. Spark By Hilton Northborough

13.6 km from Main South

Francis

CA $161 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a reception desk, seating area, and a wooden floor.

15. DoubleTree by Hilton Hotel Boston - Westborough

20.8 km from Main South

Devante

CA $181 total

includes taxes & fees

Nov 1 - Nov 2

A spacious indoor area with a central water feature, surrounded by tables and chairs, and large windows offering views of the sky and outside.

16. Best Western Royal Plaza Hotel & Trade Center

21.4 km from Main South

Joan

CA $155 total

includes taxes & fees

Nov 1 - Nov 2

A multi-story hotel with a prominent "Hyatt Place" sign, a covered entrance, and a parking lot.

17. Hyatt Place Marlborough/Apex Center

21.1 km from Main South

Christopher

CA $196 total

includes taxes & fees

Nov 1 - Nov 2

A neatly arranged hotel room with a large bed, bedside lamps, a heater, and a wardrobe.

18. Westborough Inn

16.8 km from Main South

Brendan

CA $154 total

includes taxes & fees

Oct 8 - Oct 9

A buffet with labeled food stations including omelets and cheese.

19. Holiday Inn Express & Suites Sturbridge by IHG

26.7 km from Main South

bryan

CA $159 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel dining area with a long table, chairs, and a television on the wall.

20. Hampton Inn Boston - Westborough

19.6 km from Main South

Cheri

CA $226 total

includes taxes & fees

Oct 25 - Oct 26

View all properties

Where to stay in Main South

Find the best Main South areas and neighborhoods for the activities you enjoy most. Learn more about Main South

A historic white building with two towers and green windows, located at a city intersection.

Worcester Central Business District

If you're spending some time in Worcester Central Business District, DCU Center and Mechanics Hall are top sights worth seeing.

See properties

A red bridge over a calm lake with stone steps leading up to it.

Union HIll

While Union HIll isn't home to many top sights, Union Station and The Hanover Theatre for the Performing Arts are some notable places to visit nearby.

See properties

An indoor dining area with tables and chairs, large windows, and hanging light bulbs.

Shrewsbury Street

Shrewsbury Street might not have many top sights, but Union Station and DCU Center are two attractions nearby that you can check out.

See properties

Franklin Plantation

While Franklin Plantation isn't home to many top sights, Union Station and EcoTarium are some notable places to visit nearby.

See properties

Piedmont

If you're looking for some top things to see and do in Piedmont and surrounding area, you can visit The Hanover Theatre for the Performing Arts and Mechanics Hall.

See properties

Top Main South Hotel Reviews

Publick House Historic Inn and Country Motor Lodge

10/10 Excellent

"All staff were amazingly personal and helpful, low staffing in dining room resulted in food delivered just warm not hot and long delays for food delivery. The only waitress was efficient and apologetic and very sweet. Establishment was great, food good but entrees not hot, room extensive and bake shop with coffee in am free with room was amazing!! Will be back!"

enVision Hotel Worcester Downtown

10/10 Excellent

"We made a reservation for a suite, but I didn't pay attention to the beds (king bed and sofa bed). The staff looked at our reservation and saw that there were 4 guests total and upgraded our room for us so that we had a room with a king bed and a shared room with 2 queens. AND they made this change before we even arrived. Will definitely stay here again!"

Hotels in Main South, Worcester

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Main South hotels

1. Homewood Suites By Hilton Worcester

2. Hilton Garden Inn Worcester

3. Courtyard by Marriott Worcester

4. Hampton Inn & Suites Worcester

5. AC Hotel by Marriott Worcester

6. enVision Hotel Worcester Downtown

7. Holiday Inn Express Hotel & Suites Auburn by IHG

8. Hampton Inn Auburn

9. La Quinta Inn by Wyndham Auburn Worcester

10. Comfort Inn Auburn - Worcester

11. Fairfield Inn & Suites by Marriott Worcester Auburn

12. Residence Inn by Marriott Worcester

13. Beechwood Hotel

14. Spark By Hilton Northborough

15. DoubleTree by Hilton Hotel Boston - Westborough

16. Best Western Royal Plaza Hotel & Trade Center

17. Hyatt Place Marlborough/Apex Center

18. Westborough Inn

19. Holiday Inn Express & Suites Sturbridge by IHG

20. Hampton Inn Boston - Westborough

Where to stay in Main South

Worcester Central Business District

Union HIll

Shrewsbury Street

Franklin Plantation

Piedmont

Top Main South Hotel Reviews

Publick House Historic Inn and Country Motor Lodge

Frequently asked questions

Explore a world of travel with Expedia