Title: The 10 Best Hotels Near Louisville Science Center, Louisville from CA $153 | Expedia.ca

  

[Downtown Louisville Travel Guide](https://expedia.ca/Louisville-Downtown-Louisville.dx6059557)[Louisville Science Center Car Rentals](https://expedia.ca/Car-Rentals-In-Louisville-Science-Center.d6062647.Car-Rental-Guide)[Louisville Science Center Vacations](https://expedia.ca/Louisville-Science-Center-Downtown-Louisville.d6062647.Vacation-Attraction)

![Louisville Science Center which includes outdoor art](https://images.trvl-media.com/place/6062647/6cb62b46-d29e-4c5d-8366-afc3a5f9c466.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find hotels near Louisville Science Center, Louisville from CA $153

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## Check prices for these dates

Tonight

[Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=6062647&startDate=2025-10-19&endDate=2025-10-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 20 - Oct 21](https://www.expedia.ca/Hotel-Search?regionId=6062647&startDate=2025-10-20&endDate=2025-10-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6062647&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6062647&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Top Hotels Close to Louisville Science Center

![Deluxe Single Room, 1 King Bed, River View | View from room](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f322db40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/15339a2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f5558cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/c35cecf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Grady

Downtown Louisville, 0.2 km from Louisville Science Center

9.4/10

Exceptional

(1008)

"We had a wonderful stay. Highly recommend this hotel- beautiful, great location, nice staff and a great restaurant downstairs!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amy

CA $217

CA $255 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/8fba23fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/10c56810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/6374a86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/159d1a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Distil, Autograph Collection

Downtown Louisville, 0.9 km from Louisville Science Center

9.6/10

Exceptional

(412)

"Really a nice place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeanie

CA $246

CA $289 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/5c04f012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/2c34bd2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/c99cb08d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Billiards](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/6093a6c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.2 km from Louisville Science Center

9.2/10

Wonderful

(1007)

"Very clean and comfortable property. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

CA $160

CA $188 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Louisville-Hotels-Homewood-Suites-By-Hilton-Louisville-Downtown.h21599840.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/46279487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/a276c9db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/ce1b7eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Suite, 1 King Bed, Fireplace](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/86d15582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Market Street Inn

2.1 km from Louisville Science Center

9.8/10

Exceptional

(117)

"Very historic building over 100 years old. Room is very clean and is unique, love it! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mark

CA $234

CA $264 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Louisville-Hotels-Market-Street-Inn.h9678336.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/5084ffc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/1296a89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/00f06f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/24c25575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from Louisville Science Center

9.4/10

Exceptional

(1024)

"Loved this place, close to the bars and the arena!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joe

CA $134

CA $158 total

includes taxes & fees

Oct 31 - Nov 1

[](https://www.expedia.ca/Louisville-Hotels-CAMBRiA-Hotel-Louisville-Downtown-Whiskey-Row.h57959281.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/8f8322e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/w4000h2662x0y0-c69fbcac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/5d16fd3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/22942c94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from Louisville Science Center

9.2/10

Wonderful

(483)

"Great location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lauren

CA $136

CA $160 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Louisville-Hotels-Towneplace-Suites-By-Marriott-Louisville-Downtown.h64696084.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/f0221042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brown Hotel

Downtown Louisville, 1.2 km from Louisville Science Center

9.4/10

Exceptional

(1108)

"The hotel was absolutely beautiful and we hope to visit again soon!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Danielle

CA $213

CA $251 total

includes taxes & fees

Oct 30 - Oct 31

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

![Signature Suite, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/e9ed9b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/af58ac58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Suite, 1 King Bed with Sofa bed, Kitchen, City View | Private kitchen](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/b3a591d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/56c60394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stellar Suites

East Market District, 2.2 km from Louisville Science Center

9.6/10

Exceptional

(107)

"It was so adorable and a great location!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

kendra

CA $138

CA $233 total

includes taxes & fees

Oct 20 - Oct 21

[](https://www.expedia.ca/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/107000000/106570000/106567800/106567772/b6fa06fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/107000000/106570000/106567800/106567772/1a639488.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, 1 King Bed, Non Smoking, Private Bathroom](https://images.trvl-media.com/lodging/107000000/106570000/106567800/106567772/66d6b7e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, 1 King Bed, Non Smoking, Private Bathroom](https://images.trvl-media.com/lodging/107000000/106570000/106567800/106567772/883a4eb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from Louisville Science Center

9.8/10

Exceptional

(88)

"Cealn room, breakfast was amazing. A++"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alejandro

CA $178

CA $207 total

includes taxes & fees

Oct 27 - Oct 28

[](https://www.expedia.ca/Louisville-Hotels-DuPont-Mansion-Bed-Breakfast.h106567772.Hotel-Information)

![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e108d0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/9798709f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Omni Louisville Hotel

Downtown Louisville, 0.8 km from Louisville Science Center

9.2/10

Wonderful

(1651)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Abby

CA $279

CA $329 total

includes taxes & fees

Nov 1 - Nov 2

[](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/594caae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from Louisville Science Center

9.0/10

Wonderful

(3710)

"Great place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tia

CA $192

CA $226 total

includes taxes & fees

Nov 1 - Nov 2

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/37000000/36890000/36884900/36884898/050ebd40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/37000000/36890000/36884900/36884898/4979ca88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/37000000/36890000/36884900/36884898/3ac37dcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/37000000/36890000/36884900/36884898/f3e2f52d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Moxy Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

9.2/10

Wonderful

(679)

"Great staff, location, and atmosphere. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Haley

CA $168

CA $198 total

includes taxes & fees

Oct 31 - Nov 1

[](https://www.expedia.ca/Louisville-Hotels-Moxy-Louisville-Downtown.h36884898.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/380612f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/7a04a28c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/70f22474.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/84bc2f36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Louisville Downtown by IHG

Downtown Louisville, 0.2 km from Louisville Science Center

8.8/10

Excellent

(1595)

"Super nice hotel, great breakfast, good location to downtown "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura

CA $130

CA $153 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-Downtown.h12552757.Hotel-Information)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/102000000/101360000/101356400/101356375/3b4a8f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/102000000/101360000/101356400/101356375/9d53858a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/102000000/101360000/101356400/101356375/895a7ea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/102000000/101360000/101356400/101356375/6f053941.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2.1 km from Louisville Science Center

9.4/10

Exceptional

(761)

"Good location and very clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

mirtha

CA $160

CA $188 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Louisville-Hotels-Tempo-By-Hilton-Louisville-Downtown-Nulu.h101356375.Hotel-Information)

![Dinner served](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/4e79a8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/c4d1fb67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

9.0/10

Wonderful

(1030)

"Nice room and great breakfast!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shannon

CA $183

CA $215 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![View from room](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673133/21a274da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673133/fe2338c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673133/97cd53e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673133/d9d00b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

9.0/10

Wonderful

(1003)

"We had a great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kevin

CA $162

CA $190 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Louisville-Hotels-Aloft-Louisville-Downtown.h11673133.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/6dbe73d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/9fbac853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/23bf82e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/c5a6934a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Louisville Marriott Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

9.0/10

Wonderful

(1001)

"Great Hotel. Great restaurant. Great bar. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

DON

CA $240

CA $282 total

includes taxes & fees

Oct 31 - Nov 1

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w2665h3837x3y3-e015ca48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/47891706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, dinner served, American cuisine](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/91dde8b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, rooftop bar](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/8178d3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Genevieve part of JdV by Hyatt

East Market District, 2.1 km from Louisville Science Center

9.2/10

Wonderful

(985)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Katharine

CA $189

CA $223 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/24000000/23540000/23530100/23530018/efc4acd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23540000/23530100/23530018/698ccea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/24000000/23540000/23530100/23530018/22c1b1c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/24000000/23540000/23530100/23530018/8f9a3a30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AC Hotel Louisville Downtown

East Market District, 2.1 km from Louisville Science Center

9.2/10

Wonderful

(581)

"Comfortable, great location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Trisha

CA $154

CA $182 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Louisville-Hotels-AC-Hotel-Louisville-Downtown.h23530018.Hotel-Information)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/f8482687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/0e69db21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/05585ee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/db453fbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Louisville

Downtown Louisville, 0.7 km from Louisville Science Center

8.8/10

Excellent

(1017)

"We loved our stay here!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Torre

CA $206

CA $243 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03&regionId=6062647&adults=2&sort=RECOMMENDED&openPlayBack=true)

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Save an average of 15% on thousands of hotels when you're signed in

[Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLouisville-Science-Center-Hotels.0-l6062647-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLouisville-Science-Center-Hotels.0-l6062647-0.Travel-Guide-Filter-Hotels)

## Top Louisville Science Center Hotel Reviews

![Galt House Hotel Trademark Collection by Wyndham](//images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg)

### Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent

"Amazing hotel "

[](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![21c Museum Hotel Louisville](//images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a_y.jpg)

### 21c Museum Hotel Louisville

10/10 Excellent

"Perfect location for walking Louisville "

[](https://expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Cambria Hotel Louisville Downtown-Whiskey Row](//images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/5084ffc5_y.jpg)

### Cambria Hotel Louisville Downtown-Whiskey Row

10/10 Excellent

"Room was clean and good"

[](https://expedia.ca/Louisville-Hotels-CAMBRiA-Hotel-Louisville-Downtown-Whiskey-Row.h57959281.Hotel-Information)

![Embassy Suites Louisville Downtown](//images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0_y.jpg)

### Embassy Suites Louisville Downtown

10/10 Excellent

"Room was clean, and breakfast was very good. "

[](https://expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Towneplace Suites By Marriott Louisville Downtown](//images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/8f8322e9_y.jpg)

### Towneplace Suites By Marriott Louisville Downtown

10/10 Excellent

"Great choice to visit Louisville Slugger Factory. Walking distance to there. Also walkable to plenty of shops. Really nice stay. Well maintained."

[](https://expedia.ca/Louisville-Hotels-Towneplace-Suites-By-Marriott-Louisville-Downtown.h64696084.Hotel-Information)

![The Grady](//images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f322db40_y.jpg)

### The Grady

10/10 Excellent

"Going to give a 4.8 out of five. In order for you to be a five it would be nice to have a make up mirror in the bathroom and a seat in the shower."

[](https://expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

![Holiday Inn Louisville Downtown by IHG](//images.trvl-media.com/lodging/71000000/70110000/70102100/70102082/15afb76d_y.jpg)

### Holiday Inn Louisville Downtown by IHG

10/10 Excellent

"Excellent "

[](https://expedia.ca/Louisville-Hotels-Holiday-Inn-Louisville-Downtown.h70102082.Hotel-Information)

![Louisville Marriott Downtown](//images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/6dbe73d1_y.jpg)

### Louisville Marriott Downtown

10/10 Excellent

"Very nice"

[](https://expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

![SpringHill Suites by Marriott Louisville Downtown](//images.trvl-media.com/lodging/2000000/1820000/1818500/1818408/2278ecb5_y.jpg)

### SpringHill Suites by Marriott Louisville Downtown

10/10 Excellent

"Great!!"

[](https://expedia.ca/Louisville-Hotels-SpringHill-Suites-By-Marriott-Louisville-Downtown.h1818408.Hotel-Information)

## Hotels near other Louisville Science Center attractions

[](https://www.expedia.ca/Louisville-Slugger-Museum-Hotels.0-l6062643-0.Travel-Guide-Filter-Hotels)

![Louisville Slugger Museum featuring interior views](https://images.trvl-media.com/place/6062643/cda9eeeb-8ec5-448c-8a77-ca9140c3b310.jpg)

### Louisville Slugger Museum

4.5/5 (1,200 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062643)

[](https://www.expedia.ca/Muhammad-Ali-Center-Hotels.0-l6062649-0.Travel-Guide-Filter-Hotels)

![Muhammad Ali Center showing night scenes and modern architecture](https://images.trvl-media.com/place/6062649/37bc13aa-c0fa-4731-9dbc-637f0a6b0590.jpg)

### Muhammad Ali Center

4.3/5 (298 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062649)

[](https://www.expedia.ca/Frazier-International-History-Museum-Hotels.0-l6062645-0.Travel-Guide-Filter-Hotels)

![Frazier International History Museum featuring interior views](https://images.trvl-media.com/place/6062645/9c629e58-7648-447d-9f56-6b3e71da3c6b.jpg)

### Frazier International History Museum

Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062645)

[](https://www.expedia.ca/Kentucky-Center-For-The-Performing-Arts-Hotels.0-l6062653-0.Travel-Guide-Filter-Hotels)

![Kentucky Center for the Performing Arts featuring modern architecture](https://images.trvl-media.com/place/6062653/8b326703-a711-4dce-a0ec-21ab55344b9a.jpg)

### Kentucky Center for the Performing Arts

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062653)

[](https://www.expedia.ca/Kentucky-Museum-Of-Art-And-Craft-Hotels.0-l6062657-0.Travel-Guide-Filter-Hotels)

### Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062657)

[](https://www.expedia.ca/Golden-Statue-Of-David-Hotels.0-l866963824899928064-0.Travel-Guide-Filter-Hotels)

### Golden Statue of David

Find out about the history of Louisville when you take a trip to Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=866963824899928064)

[](https://www.expedia.ca/SAR-Genealogical-Research-Library-NSSAR-Library-Hotels.0-l553248621558115021-0.Travel-Guide-Filter-Hotels)

### SAR Genealogical Research Library: NSSAR Library

You can spend an afternoon browsing the exhibits at SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558115021)

[](https://www.expedia.ca/Louisville-Glassworks-Hotels.0-l6062655-0.Travel-Guide-Filter-Hotels)

### Louisville Glassworks

You can spend an afternoon studying the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062655)

## Frequently asked questions

### What's the area like around Louisville Science Center?

> Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 290 hotels and other accommodations you'll find within a mile.

### What's the best place to stay near Louisville Science Center?

> Adjacent to Louisville Science Center, [Holiday Inn Express & Suites Louisville Downtown by IHG](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-Downtown.h12552757.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include [Galt House Hotel Trademark Collection by Wyndham](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) and [Omni Louisville Hotel](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information).

### How many hotels can I expect to find close to Louisville Science Center?

> Expedia has 290 hotels and other accommodations within a mile from Louisville Science Center.

### If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

> Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.

### What can I see and do near Louisville Science Center?

> 21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Thomas Edison House. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace, and Derby Dinner Playhouse.

## Explore a world of travel with Expedia

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-   [Romantic Hotels in Louisville](https://www.expedia.ca/Louisville-Hotels-Romantic-Hotel.0-0-d603002-tRomanticHotel.Travel-Guide-Filter-Hotels)
-   [Spa Hotels in Louisville](https://www.expedia.ca/Louisville-Hotels-Spa-Hotel.0-0-d603002-tSpaHotel.Travel-Guide-Filter-Hotels)
-   [Waterpark Hotels in Louisville](https://www.expedia.ca/Louisville-Hotels-Waterpark-Hotels.0-0-d603002-tWaterparkHotels.Travel-Guide-Filter-Hotels)
-   [Louisville Hotels](https://www.expedia.ca/Louisville-Hotels.d603002.Travel-Guide-Hotels)
-   [Inns in Louisville](https://www.expedia.ca/Louisville-Inns.d603002-aaInns.Travel-Guide-Accommodation)
-   [Lodges in Louisville](https://www.expedia.ca/Louisville-Lodges.d603002-aaLodges.Travel-Guide-Accommodation)
-   [Motels in Louisville](https://www.expedia.ca/Louisville-Motels.d603002-aaMotels.Travel-Guide-Accommodation)
-   [Hotels near Louisville Palace](https://www.expedia.ca/Louisville-Palace-Hotels.0-l6062675-0.Travel-Guide-Filter-Hotels)
-   [Resorts in Louisville](https://www.expedia.ca/Louisville-Resort-Hotels.d603002-aaResortHotels.Travel-Guide-Accommodation)
-   [Hotels near Louisville Slugger Field](https://www.expedia.ca/Louisville-Slugger-Field-Hotels.0-l6295027-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Louisville Slugger Museum](https://www.expedia.ca/Louisville-Slugger-Museum-Hotels.0-l6062643-0.Travel-Guide-Filter-Hotels)
-   [Treehouses in Louisville](https://www.expedia.ca/Louisville-Treehouses.d603002-aaTreehouses.Travel-Guide-Accommodation)
-   [Hotels near Lynn Family Stadium](https://www.expedia.ca/Lynn-Family-Stadium-Hotels.0-l676726685092388864-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Muhammad Ali Center](https://www.expedia.ca/Muhammad-Ali-Center-Hotels.0-l6062649-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Nulu Market Place](https://www.expedia.ca/Nulu-Market-Place-Hotels.0-l803578443506188288-0.Travel-Guide-Filter-Hotels)
-   [Old Louisville Hotels](https://www.expedia.ca/Old-Louisville-Louisville-Hotels.0-n6338738-0.Travel-Guide-Filter-Hotels)
-   [Phoenix Hill Hotels](https://www.expedia.ca/Phoenix-Hill-Louisville-Hotels.0-n553248635976384799-0.Travel-Guide-Filter-Hotels)
-   [Shelby Park Hotels](https://www.expedia.ca/Shelby-Park-Louisville-Hotels.0-n553248635976384163-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Union Station](https://www.expedia.ca/Union-Station-Hotels.0-l553248621559724910-0.Travel-Guide-Filter-Hotels)
-   [Boutique Hotels in West Main Historic District](https://www.expedia.ca/West-Main-Historic-District-Louisville-Hotels-Boutique-Hotel.0-n6338837-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
-   [Hotels & Resorts for Couples in West Main Historic District](https://www.expedia.ca/West-Main-Historic-District-Louisville-Hotels-Couples-Resorts-Hotels.0-n6338837-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
-   [West Main Historic District Hotels](https://www.expedia.ca/West-Main-Historic-District-Louisville-Hotels.0-n6338837-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Whiskey Row](https://www.expedia.ca/Whiskey-Row-Hotels.0-l710255723734024192-0.Travel-Guide-Filter-Hotels)

-   [Flights to Louisville](https://www.expedia.ca/Cheap-Flights-To-Louisville.d603002.Travel-Guide-Flights)
-   [Flights from Louisville](https://www.expedia.ca/lp/flights/603002/flights-from-louisville)

-   [Belle of Louisville](https://www.expedia.ca/Belle-Of-Louisville-Downtown-Louisville.d6062661.Vacation-Attraction)
-   [Kfc Yum Center](https://www.expedia.ca/KFC-Yum-Center-Downtown-Louisville.d6140365.Vacation-Attraction)
-   [Louisville Slugger Museum](https://www.expedia.ca/Louisville-Slugger-Museum-Downtown-Louisville.d6062643.Vacation-Attraction)
-   [Louisville Vacations](https://www.expedia.ca/Louisville.d603002.Destination-Travel-Guides)
-   [Visit Louisville](https://www.expedia.ca/Louisville.dx603002)
-   [Muhammad Ali Center](https://www.expedia.ca/Muhammad-Ali-Center-Downtown-Louisville.d6062649.Vacation-Attraction)
-   [Riverfront Plaza Belvedere](https://www.expedia.ca/Riverfront-Plaza-Belvedere-Downtown-Louisville.d6062651.Vacation-Attraction)

-   [Car rentals near Belle of Louisville](https://www.expedia.ca/Car-Rentals-In-Belle-Of-Louisville.d6062661.Car-Rental-Guide)
-   [Car rentals near Louisville](https://www.expedia.ca/Car-Rentals-In-Louisville.d603002.Car-Rental-Guide)
-   [Easirent Rental Cars in Louisville](https://www.expedia.ca/Easirent-Car-Rentals-In-Louisville.d603002-c1039.Car-Rental-Guide-Suppliers)
-   [Luxury Car Rentals in Louisville](https://www.expedia.ca/Luxury-Car-Rentals-In-Louisville.d603002-tLuxury.Car-Rental-Guide-Class)
-   [Pickup Car Rentals in Louisville](https://www.expedia.ca/Pickup-Car-Rentals-In-Louisville.d603002-tPickup.Car-Rental-Guide-Class)

-   [Louisville Vacation Rentals](https://www.expedia.ca/Louisville-Vacation-Rentals.d603002.Travel-Guide-VacationRentals)

-   [Things to do in Louisville](https://www.expedia.ca/Things-To-Do-In-Louisville.d603002.Travel-Guide-Activities)