Title: The 10 Best Hotels Near Louisville Science Center, Louisville from CA $143 | Expedia.ca

[Downtown Louisville Travel Guide](https://expedia.ca/Louisville-Downtown-Louisville.dx6059557)[Louisville Science Center Car Rentals](https://expedia.ca/Car-Rentals-In-Louisville-Science-Center.d6062647.Car-Rental-Guide)[Louisville Science Center Vacations](https://expedia.ca/Louisville-Science-Center-Downtown-Louisville.d6062647.Vacation-Attraction)

![Louisville Science Center showing signage](https://images.trvl-media.com/place/6062647/da3ea6c6-ce78-45c0-8a8d-660434d5aefb.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6062647/da3ea6c6-ce78-45c0-8a8d-660434d5aefb.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

Tonight

[Mar 4 - Mar 5](https://www.expedia.ca/Hotel-Search?regionId=6062647&startDate=2026-03-04&endDate=2026-03-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 5 - Mar 6](https://www.expedia.ca/Hotel-Search?regionId=6062647&startDate=2026-03-05&endDate=2026-03-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6062647&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6062647&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Louisville Science Center hotels

![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/2c34bd2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Billiards](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/6093a6c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/5c04f012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/44227afb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Homewood Suites by Hilton Louisville Downtown, KY

[](https://www.expedia.ca/Louisville-Hotels-Homewood-Suites-By-Hilton-Louisville-Downtown.h21599840.Hotel-Information)

Downtown Louisville, 0.2 km from Louisville Science Center

9.4/10

Exceptional

(1,003 reviews)

"Beautiful pristine accommodation … great swim next morning before delicious breakfast designed for all tastes… all in all a wonderful treat!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

BRENDA

CA $151

CA $177 total

includes taxes & fees

Mar 22 - Mar 23

[](https://www.expedia.ca/Louisville-Hotels-Homewood-Suites-By-Hilton-Louisville-Downtown.h21599840.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e116c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Single Room, 1 King Bed, City View](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f924fe21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f5558cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e68de90e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Grady

[](https://www.expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

Downtown Louisville, 0.2 km from Louisville Science Center

9.4/10

Exceptional

(1,003 reviews)

"Such an amazing hotel...restaurant is delicious! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Craig

CA $235

CA $276 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/06213b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

Downtown Louisville, < 0.1 km from Louisville Science Center

9.4/10

Exceptional

(1,006 reviews)

"Great room, super kind staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rachel

CA $245

CA $295 total

includes taxes & fees

Mar 22 - Mar 23

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/ac66f01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/16484a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/939655b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/8fba23fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Distil, Autograph Collection

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

Downtown Louisville, 0.9 km from Louisville Science Center

9.6/10

Exceptional

(453 reviews)

"Great hotel & location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ana

CA $251

CA $296 total

includes taxes & fees

Mar 22 - Mar 23

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/56e486f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Suite | Terrace/patio](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/2ccf1a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/81948b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/00819013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Louisville Bourbon Inn

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Bourbon-Inn.h101176472.Hotel-Information)

Old Louisville, 2.9 km from Louisville Science Center

10/10

Exceptional

(22 reviews)

"Absolutely the best B&B we have ever stayed with."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Roy

CA $362

CA $421 total

includes taxes & fees

Mar 9 - Mar 10

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Bourbon-Inn.h101176472.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/a276c9db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/9d6b5686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Suite, 1 King Bed, Fireplace](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/86d15582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/d64d36b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Market Street Inn

[](https://www.expedia.ca/Louisville-Hotels-Market-Street-Inn.h9678336.Hotel-Information)

2.1 km from Louisville Science Center

9.8/10

Exceptional

(120 reviews)

"Warm greeting by Carol who shared all the information and details about the property. SUPER charming and convenient location. Highly recommend."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kelly

CA $253

CA $286 total

includes taxes & fees

Mar 31 - Apr 1

[](https://www.expedia.ca/Louisville-Hotels-Market-Street-Inn.h9678336.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/24ad9fc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/0a1fd80c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/4414376c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/a7105af5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cambria Hotel Louisville Downtown-Whiskey Row

[](https://www.expedia.ca/Louisville-Hotels-CAMBRiA-Hotel-Louisville-Downtown-Whiskey-Row.h57959281.Hotel-Information)

Downtown Louisville, 1.2 km from Louisville Science Center

9.4/10

Exceptional

(1,002 reviews)

"Great stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sarah

CA $149

CA $176 total

includes taxes & fees

Mar 20 - Mar 21

[](https://www.expedia.ca/Louisville-Hotels-CAMBRiA-Hotel-Louisville-Downtown-Whiskey-Row.h57959281.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/764d3439.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/f0221042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brown Hotel

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

Downtown Louisville, 1.2 km from Louisville Science Center

9.4/10

Exceptional

(1,186 reviews)

"Beautiful old hotel with a fantastic bar in the lobby"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/22942c94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/8f8322e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/w4000h2662x0y0-c69fbcac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/68fd48ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Towneplace Suites By Marriott Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Towneplace-Suites-By-Marriott-Louisville-Downtown.h64696084.Hotel-Information)

Downtown Louisville, 0.3 km from Louisville Science Center

9.2/10

Wonderful

(553 reviews)

"The hotel is so clean and easy access to everything downtown."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erin

CA $144

CA $169 total

includes taxes & fees

Apr 4 - Apr 5

[](https://www.expedia.ca/Louisville-Hotels-Towneplace-Suites-By-Marriott-Louisville-Downtown.h64696084.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/107000000/106570000/106567800/106567772/404cfdd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/107000000/106570000/106567800/106567772/1a639488.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/107000000/106570000/106567800/106567772/8c0d6edc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/107000000/106570000/106567800/106567772/95a15c05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DuPont Mansion Bed & Breakfast

[](https://www.expedia.ca/Louisville-Hotels-DuPont-Mansion-Bed-Breakfast.h106567772.Hotel-Information)

Old Louisville, 2.8 km from Louisville Science Center

9.8/10

Exceptional

(107 reviews)

"Breakfast was wonderful, great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janie

CA $182

CA $212 total

includes taxes & fees

Mar 11 - Mar 12

[](https://www.expedia.ca/Louisville-Hotels-DuPont-Mansion-Bed-Breakfast.h106567772.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/3f80acf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/af58ac58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/89d26e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Suite, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/e9ed9b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stellar Suites

[](https://www.expedia.ca/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

East Market District, 2.2 km from Louisville Science Center

9.6/10

Exceptional

(124 reviews)

"The check-in process was simple and easy, the room was spotless and had so many amenities. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Grace

CA $136

CA $230 total

includes taxes & fees

Mar 31 - Apr 1

[](https://www.expedia.ca/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/aa5bcd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/63654a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/0261f02d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

Downtown Louisville, 0.5 km from Louisville Science Center

9.0/10

Wonderful

(4,091 reviews)

"Rooms were clean and staff were friendly! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amy

CA $173

CA $203 total

includes taxes & fees

Mar 31 - Apr 1

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/37000000/36890000/36884900/36884898/1b912f09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/37000000/36890000/36884900/36884898/9b2693c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/37000000/36890000/36884900/36884898/f4939e30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/37000000/36890000/36884900/36884898/2519f254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Moxy Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Moxy-Louisville-Downtown.h36884898.Hotel-Information)

Downtown Louisville, 0.9 km from Louisville Science Center

9.2/10

Wonderful

(721 reviews)

"Great stay. Great location and good food. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bryson

CA $133

CA $156 total

includes taxes & fees

Mar 22 - Mar 23

[](https://www.expedia.ca/Louisville-Hotels-Moxy-Louisville-Downtown.h36884898.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/5c616865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/c93e1deb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, American cuisine](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/12fca7c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/f1158083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Bourré Bonne Louisville, Curio Collection by Hilton

[](https://www.expedia.ca/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

Downtown Louisville, 0.8 km from Louisville Science Center

9.2/10

Wonderful

(77 reviews)

"i love this place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

THANH

CA $196

CA $231 total

includes taxes & fees

Apr 4 - Apr 5

[](https://www.expedia.ca/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/102000000/101360000/101356400/101356375/3b4a8f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/102000000/101360000/101356400/101356375/d3b8cc18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/102000000/101360000/101356400/101356375/895a7ea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/102000000/101360000/101356400/101356375/aade8236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tempo By Hilton Louisville Downtown Nulu

[](https://www.expedia.ca/Louisville-Hotels-Tempo-By-Hilton-Louisville-Downtown-Nulu.h101356375.Hotel-Information)

Phoenix Hill, 2.1 km from Louisville Science Center

9.4/10

Exceptional

(936 reviews)

"Always a great place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christopher

CA $123

CA $145 total

includes taxes & fees

Apr 4 - Apr 5

[](https://www.expedia.ca/Louisville-Hotels-Tempo-By-Hilton-Louisville-Downtown-Nulu.h101356375.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/40953e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/7a04a28c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/84bc2f36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/cbf0696c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Louisville Downtown by IHG

[](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-Downtown.h12552757.Hotel-Information)

Downtown Louisville, 0.2 km from Louisville Science Center

8.8/10

Excellent

(1,714 reviews)

"Room was clean and the beds were very comfortable. Would definitely stay here again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Talva

CA $122

CA $143 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-Downtown.h12552757.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking, Corner | Living area](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/07f1fa14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/408d438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

Downtown Louisville, 0.8 km from Louisville Science Center

9.0/10

Wonderful

(1,159 reviews)

"Great room and breakfast. Close to several nice restaurants."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Crystal

CA $157

CA $185 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673133/25ff2155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673133/97cd53e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673133/53115960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673133/fe2338c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Aloft-Louisville-Downtown.h11673133.Hotel-Information)

Downtown Louisville, 0.9 km from Louisville Science Center

9.0/10

Wonderful

(1,002 reviews)

"Great staff, good bar. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Edward

CA $143

CA $168 total

includes taxes & fees

Mar 31 - Apr 1

[](https://www.expedia.ca/Louisville-Hotels-Aloft-Louisville-Downtown.h11673133.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/1b9613a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w2691h3837x0y3-df7daefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, cocktail bar, rooftop bar](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/8178d3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w3836h2558x4y3-11fbb096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Genevieve part of JdV by Hyatt

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

East Market District, 2.1 km from Louisville Science Center

9.2/10

Wonderful

(1,049 reviews)

"Spotless room and courteous staff "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

CA $185

CA $217 total

includes taxes & fees

Mar 19 - Mar 20

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/c5a6934a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 Bedroom | Living area](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/14a187ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/19be2c84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 Bedroom](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/1c073add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Louisville Marriott Downtown

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

Downtown Louisville, 0.8 km from Louisville Science Center

9.0/10

Wonderful

(1,002 reviews)

"Very nice hotel. Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brad

CA $229

CA $270 total

includes taxes & fees

Apr 4 - Apr 5

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-18&endDate=2026-03-19&regionId=6062647&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Louisville Science Center Hotel Reviews

![Embassy Suites Louisville Downtown](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0_y.jpg)

### Embassy Suites Louisville Downtown

10/10 Excellent

"Clean. Great lobby and location with friendly staff! "

[](https://expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Holiday Inn Express & Suites Louisville Downtown by IHG](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/380612f2_y.jpg)

### Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent

"Clean, quiet, very comfortable"

[](https://expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-Downtown.h12552757.Hotel-Information)

![21c Museum Hotel Louisville](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a_y.jpg)

### 21c Museum Hotel Louisville

10/10 Excellent

"The rooms and staff were great and the penguins were alive. "

[](https://expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Hyatt Regency Louisville](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/f8482687_y.jpg)

### Hyatt Regency Louisville

8/10 Good

"Nice hotel. Clean. Friendly staff. Right in the heart of downtown but it's a dead downtown. Shadow if its pre pandemic self"

[](https://expedia.ca/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

![Omni Louisville Hotel](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b_y.jpg)

### Omni Louisville Hotel

10/10 Excellent

"The staff at the Omni provided outstanding customer service that exceeded our expectations. They were quick to provide solutions and answer our questions. Terrence and Amanda went out of their way to make sure our stay was top notch. They were kind, polite and provided excellent, charismastic, customer service!"

[](https://expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

![Hilton Garden Inn Louisville Downtown](https://images.trvl-media.com/lodging/10000000/9220000/9215400/9215348/d064e9c8_y.jpg)

### Hilton Garden Inn Louisville Downtown

10/10 Excellent

"Comfortable "

[](https://expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Louisville-Downtown.h9215348.Hotel-Information)

![The Grady](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f322db40_y.jpg)

### The Grady

8/10 Good

"The best part about the Grady is its excellent location in historical Louisville. We walked to many attractions and restaurants. The room was clean and comfortable but not a lot of extras to it. Bed and bedding were great. We had an excellent breakfast in the Wild Swann restaurant on site. We chose to park our car at a nearby garage for $22/day. It was a half block away. "

[](https://expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

![Galt House Hotel Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg)

### Galt House Hotel Trademark Collection by Wyndham

8/10 Good

"No microwave, pullout sofa, trash bags for cans or extra sheets. Just a one night stay but these are basic things."

[](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![The Brown Hotel](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de_y.jpg)

### The Brown Hotel

8/10 Good

"Second time around for our anniversary. Room wasn’t as nice,but still comfortable. Restaurant bar and servers were great! I’m sure we’ll be back again. "

[](https://expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

## Hotels near other Louisville Science Center attractions

![Exploration of Louisville Slugger Museum in Downtown Louisville, Kentucky on a Sunny Day](https://images.trvl-media.com/place/6062643/51fb1d89-9725-43b9-9f70-fb542b492925.jpg)

### Louisville Slugger Museum

4.5/5 (1,200 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062643)

![A great stop! This has to be one of the best museums I’ve been about somebody! Great stop and a fantastic life!](https://images.trvl-media.com/place/3108/7c78e7c9-eac0-4b50-9e66-c8627c15b771.jpg)

Photo by Corey Dargan

### Muhammad Ali Center

4.3/5 (298 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062649)

![Frazier International History Museum](https://images.trvl-media.com/place/6062645/f15343bb-d94c-489f-93a1-061de9db7d6f.jpg)

### Frazier International History Museum

Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062645)

![Kentucky Center for the Performing Arts](https://images.trvl-media.com/place/6062653/7002efac-f43e-4dcd-8f15-f5c426433d39.jpg)

### Kentucky Center for the Performing Arts

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062653)

### Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062657)

### Golden Statue of David

Find out about the history of Louisville when you take a trip to Golden Statue of David. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=866963824899928064)

### SAR Genealogical Research Library: NSSAR Library

You can spend an afternoon browsing the exhibits at SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558115021)

### Louisville Glassworks

You can spend an afternoon studying the exhibits at Louisville Glassworks in Louisville. Experience the area's great live music or attend a sporting event. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6062655)

## Frequently asked questions

### What's the area like around Louisville Science Center?

### What's the best place to stay near Louisville Science Center?

### How many hotels can I expect to find close to Louisville Science Center?

### If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

### What can I see and do near Louisville Science Center?

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- [Resorts in Louisville ](https://www.expedia.ca/Louisville-Resort-Hotels.d603002-aaResortHotels.Travel-Guide-Accommodation)
- [Hotels near Louisville Slugger Field ](https://www.expedia.ca/Louisville-Slugger-Field-Hotels.0-l6295027-0.Travel-Guide-Filter-Hotels)
- [Hotels near Louisville Slugger Museum ](https://www.expedia.ca/Louisville-Slugger-Museum-Hotels.0-l6062643-0.Travel-Guide-Filter-Hotels)
- [Treehouses in Louisville ](https://www.expedia.ca/Louisville-Treehouses.d603002-aaTreehouses.Travel-Guide-Accommodation)
- [Hotels near Lynn Family Stadium ](https://www.expedia.ca/Lynn-Family-Stadium-Hotels.0-l676726685092388864-0.Travel-Guide-Filter-Hotels)
- [Hotels near Muhammad Ali Center ](https://www.expedia.ca/Muhammad-Ali-Center-Hotels.0-l6062649-0.Travel-Guide-Filter-Hotels)
- [Hotels near Nulu Market Place ](https://www.expedia.ca/Nulu-Market-Place-Hotels.0-l803578443506188288-0.Travel-Guide-Filter-Hotels)
- [Old Louisville Hotels ](https://www.expedia.ca/Old-Louisville-Louisville-Hotels.0-n6338738-0.Travel-Guide-Filter-Hotels)
- [Phoenix Hill Hotels ](https://www.expedia.ca/Phoenix-Hill-Louisville-Hotels.0-n553248635976384799-0.Travel-Guide-Filter-Hotels)
- [Shelby Park Hotels ](https://www.expedia.ca/Shelby-Park-Louisville-Hotels.0-n553248635976384163-0.Travel-Guide-Filter-Hotels)
- [Hotels near Union Station ](https://www.expedia.ca/Union-Station-Hotels.0-l553248621559724910-0.Travel-Guide-Filter-Hotels)
- [Boutique Hotels in West Main Historic District ](https://www.expedia.ca/West-Main-Historic-District-Louisville-Hotels-Boutique-Hotel.0-n6338837-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
- [Hotels & Resorts for Couples in West Main Historic District ](https://www.expedia.ca/West-Main-Historic-District-Louisville-Hotels-Couples-Resorts-Hotels.0-n6338837-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
- [West Main Historic District Hotels ](https://www.expedia.ca/West-Main-Historic-District-Louisville-Hotels.0-n6338837-0.Travel-Guide-Filter-Hotels)
- [Hotels near Whiskey Row ](https://www.expedia.ca/Whiskey-Row-Hotels.0-l710255723734024192-0.Travel-Guide-Filter-Hotels)

- [Flights to Louisville ](https://www.expedia.ca/Cheap-Flights-To-Louisville.d603002.Travel-Guide-Flights)
- [Flights from Louisville ](https://www.expedia.ca/lp/flights/603002/flights-from-louisville)

- [Belle of Louisville ](https://www.expedia.ca/Belle-Of-Louisville-Downtown-Louisville.d6062661.Vacation-Attraction)
- [Kfc Yum Center ](https://www.expedia.ca/KFC-Yum-Center-Downtown-Louisville.d6140365.Vacation-Attraction)
- [Louisville Slugger Museum ](https://www.expedia.ca/Louisville-Slugger-Museum-Downtown-Louisville.d6062643.Vacation-Attraction)
- [Louisville Vacations ](https://www.expedia.ca/Louisville.d603002.Destination-Travel-Guides)
- [Visit Louisville ](https://www.expedia.ca/Louisville.dx603002)
- [Muhammad Ali Center ](https://www.expedia.ca/Muhammad-Ali-Center-Downtown-Louisville.d6062649.Vacation-Attraction)
- [Riverfront Plaza Belvedere ](https://www.expedia.ca/Riverfront-Plaza-Belvedere-Downtown-Louisville.d6062651.Vacation-Attraction)

- [Car rentals near Belle of Louisville ](https://www.expedia.ca/Car-Rentals-In-Belle-Of-Louisville.d6062661.Car-Rental-Guide)
- [Car rentals near Louisville ](https://www.expedia.ca/Car-Rentals-In-Louisville.d603002.Car-Rental-Guide)
- [Easirent Rental Cars in Louisville ](https://www.expedia.ca/Easirent-Car-Rentals-In-Louisville.d603002-c1039.Car-Rental-Guide-Suppliers)
- [Luxury Car Rentals in Louisville ](https://www.expedia.ca/Luxury-Car-Rentals-In-Louisville.d603002-tLuxury.Car-Rental-Guide-Class)
- [Pickup Car Rentals in Louisville ](https://www.expedia.ca/Pickup-Car-Rentals-In-Louisville.d603002-tPickup.Car-Rental-Guide-Class)

- [Louisville Vacation Rentals ](https://www.expedia.ca/Louisville-Vacation-Rentals.d603002.Travel-Guide-VacationRentals)

- [Things to do in Louisville ](https://www.expedia.ca/Things-To-Do-In-Louisville.d603002.Travel-Guide-Activities)