Title: Hotels by Best Western in Los Osos from CA $142 | Expedia.ca [Los Osos Travel Guide](https://expedia.ca/Los-Osos.dx9873)[Hotels in Los Osos](https://expedia.ca/Los-Osos-Hotels.d9873.Travel-Guide-Hotels)[Vacation Rentals in Los Osos](https://expedia.ca/Los-Osos-Vacation-Rentals.d9873.Travel-Guide-VacationRentals)[Flights to Los Osos](https://expedia.ca/Cheap-Flights-To-Los-Osos.d9873.Travel-Guide-Flights)[Things to do in Los Osos](https://expedia.ca/Things-To-Do-In-Los-Osos.d9873.Travel-Guide-Activities)[Los Osos Car Rentals](https://expedia.ca/Car-Rentals-In-Los-Osos.d9873.Car-Rental-Guide)[Los Osos Vacation Packages](https://expedia.ca/Los-Osos.d9873.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/82ae60cf1761badedca5aae03e4e0866.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Best Western in Los Osos from CA $142 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 6 - Nov 7](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-11-06&endDate=2025-11-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=9873&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Los Osos Best Western Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/e16ece78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/a9f9803a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/8d75e25e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/4cda8af4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Casa Grande Inn Pismo Beach 8.8/10 Excellent (1136) "It was very nice we loved it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lenna CA $125 CA $142 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Casa-Grande-Inn.h23008.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/27300/27231/e3a526b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27300/27231/3a1ea037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27300/27231/7ec2d31d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Balcony, Ocean View](https://images.trvl-media.com/lodging/1000000/30000/27300/27231/23289d11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western San Marcos Inn Downtown Morro Bay 8.4/10 Very good (905) "clean and friendly staff, love this property " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandro CA $131 CA $150 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-San-Marcos-Inn.h27231.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25400/25360/add350f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25400/25360/dc4919fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25400/25360/84a45151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/25400/25360/5c418938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Tradewinds Morro Bay 8.2/10 Very good (860) "Nothing bad to say-Base room for a base price. Breakfast was good and area was quiet. Long hair hanging from the exhaust fan in the bathroom is my only complaint." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alfred CA $128 CA $147 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Morro-Bay-Hotels-Best-Western-Tradewinds.h25360.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-19&endDate=2025-11-20®ionId=9873&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLos-Osos-Hotels-Best-Western.0-0-d9873--bBestWestern.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLos-Osos-Hotels-Best-Western.0-0-d9873--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Los Osos Hotel Reviews ![La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown](//images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/99fa5dc7_y.jpg) ### La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown 10/10 Excellent "Clean and comfortable. TV was impossible to make work in a functional way. " [](https://expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information) ![Madonna Inn](//images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg) ### Madonna Inn 10/10 Excellent "Great room - Merry. 20 foot ceiling with pink glittery wall paper and a large gold and crystal light fixtures and giant chandelier. Quirky hotel (as expected) but well maintained. Nice pool area. Signature pink cloud cocktail was very . . . pink (and tasted fine)! Wonderful meal at the steak house. Pink champagne cake was pretty amazing and lived up to the hype. Waterfall urinal in men's room near the restaurant was over the top! Would stay here again. Should have broken up the long drive from LA to the Bay Area with a stay here long ago. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Oxford Suites Pismo Beach](//images.trvl-media.com/lodging/1000000/10000/3100/3089/b427747a_y.jpg) ### Oxford Suites Pismo Beach 10/10 Excellent "Great breakfast!" [](https://expedia.ca/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Lamplighter Inn & Suites](//images.trvl-media.com/lodging/1000000/190000/181200/181126/92ba94b3_y.jpg) ### Lamplighter Inn & Suites 10/10 Excellent "This is my 2nd stay and I liked it a lot. The 24 hour office is a plus. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Lamplighter-Inn-Suites.h181126.Hotel-Information) ![Embassy Suites by Hilton San Luis Obispo](//images.trvl-media.com/lodging/1000000/20000/15500/15406/48c2929b_y.jpg) ### Embassy Suites by Hilton San Luis Obispo 10/10 Excellent "Nice breakfast clean room very helpful staff" [](https://expedia.ca/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![Shore Cliff Hotel](//images.trvl-media.com/lodging/1000000/10000/9800/9742/ff9d613b_y.jpg) ### Shore Cliff Hotel 10/10 Excellent "Staff, view, amenities." [](https://expedia.ca/San-Luis-Obispo-Hotels-Shore-Cliff-Hotel.h9742.Hotel-Information) ![Edgewater Inn And Suites](//images.trvl-media.com/lodging/1000000/900000/894000/893902/3d1c5694_y.jpg) ### Edgewater Inn And Suites 10/10 Excellent "Room was very clean, staff friendly, extras like snacks and grab and go breakfast. Will stay here again." [](https://expedia.ca/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ![Cottage Inn By The Sea](//images.trvl-media.com/lodging/1000000/160000/151000/150921/c54d7346_y.jpg) ### Cottage Inn By The Sea 10/10 Excellent "Beautiful views and it is a very clean hotel" [](https://expedia.ca/San-Luis-Obispo-Hotels-Cottage-Inn-By-The-Sea.h150921.Hotel-Information) ![Harbor House Inn Morro Bay](//images.trvl-media.com/lodging/1000000/80000/79600/79558/3e3fd2a1_y.jpg) ### Harbor House Inn Morro Bay 10/10 Excellent "It is such a nice place. A+!!" 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