Uptown - Upper Duval
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
4/5(161 reviews)
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
4/5(54 reviews)
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.
Key West Butterfly and Nature Conservatory
4.5/5(19 reviews)
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
CA $61
per adult
94% of travellers recommend
Historic Key West Old Town Trolley Hop-On Hop-Off Tour
CA $76
per adult
88% of travellers recommend
Key West Coral Reef Snorkel with Mimosas, Margaritas or Rum Punch
CA $75
per adult
86% of travellers recommend
Key West Sunset Sail with Live Music, Drinks and Appetizers!
CA $109
per traveller
92% of travellers recommend
Key West Rum & Reggae: Snorkel & Sunset Sail Combo
CA $75
per adult
88% of travellers recommend
Key West Afternoon At The Reef Snorkeling Adventure with Open Bar!
CA $65
per adult
90% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
The price is CA $290 per night from Jun 16 to Jun 17
CA $290
CA $427 total
Jun 16 - Jun 17
includes taxes & fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,337 reviews)
"Our shower leaked all over the bathroom. Front desk staff was rude everyday. Very limited pool chairs. Pools were cloudy and could have used a good cleaning."
Reviewed on May 20, 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
The price is CA $173 per night from May 26 to May 27
CA $173
CA $256 total
May 26 - May 27
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.4/10 Very Good! (1,365 reviews)
"Overall a solid option for the price and the location is right off Duvall!"
Reviewed on May 20, 2026
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
The price is CA $306 per night from Jun 9 to Jun 10
CA $306
CA $437 total
Jun 9 - Jun 10
includes taxes & fees
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,011 reviews)
"Beautiful private beach. Nice pool, beautiful grounds, nicely appointed rooms. A paradise witin a paradise."
Reviewed on May 19, 2026
Southwinds Motel
1321 Simonton Street Key West FL
The price is CA $207 per night from May 26 to May 27
CA $207
CA $280 total
May 26 - May 27
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,355 reviews)
"Clean room. Everything is in walking distance. The room itself was super small and tight once you start living there."
Reviewed on May 18, 2026
Douglas House - Adults Only
419 Amelia St Key West FL
The price is CA $207 per night from May 26 to May 27
CA $207
CA $256 total
May 26 - May 27
includes taxes & fees
Stay at this guesthouse in Key West. Enjoy free WiFi, daily housekeeping, and a garden. Popular attractions Duval Street and Ernest Hemingway Home and Museum ...
9.6/10 Exceptional! (389 reviews)
"Beautiful property, close to everything. The employee's were also super nice and attentive. We can't wait to come back!!"
Reviewed on May 19, 2026
Santa Maria Suites
1401 Simonton St Key West FL
The price is CA $425 per night from May 27 to May 28
CA $425
CA $571 total
May 27 - May 28
includes taxes & fees
Stay at this resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,008 reviews)
"A ++"
Reviewed on May 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Uptown - Upper Duval hotel availability
Other neighbourhoods around Uptown - Upper Duval
Old Town Key West
3.5/5(8 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Bahama Village
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Key West Historic District
4.5/5(157 area reviews)
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Florida Keys Beaches and Clarence S. Higgs Memorial Beach Park.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.
Uptown - Upper Duval
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- Visit Bahia Honda Key
- Visit Big Coppitt Key
- Visit Doctor's Arm
- Visit Big Pine Key
- Visit Big Torch Key
- Visit Boca Chica Key
- Visit Cow Key
- Visit Cudjoe Key
- Visit Dredgers Key
- Visit Duck Key
- Visit Fleming Key
- Visit Grassy Key
- Visit Bahama Village
- Visit Downtown Key West
- Visit Historic Seaport
- Visit Key West Historic District
- Key West Lighthouse and Keeper's Quarters Museum
- Visit Northside Resort
- Visit White Street Gallery District
- Key West Vacations
- Visit Key West
- Visit Little Torch Key
- Visit Lower Florida Keys
- Visit Marathon
- Visit Melody Key
- Visit No Name Key
- Visit No Name Key
- Visit Ramrod Key
- Visit Rockland Key
- South Beach
- Southernmost Point
- Visit Stock Island
- Visit Sugarloaf Key
- Visit Summerland Key
- All inclusive Vacation Packages Key West
