Uptown - Upper Duval
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
4/5(160 reviews)
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
4/5(52 reviews)
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.
Key West Butterfly and Nature Conservatory
4.5/5(19 reviews)
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
CA $55
per adult
92% of travellers recommend
Historic Key West Old Town Trolley Hop-On Hop-Off Tour
CA $76
per adult
86% of travellers recommend
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
CA $38
per adult
78% of travellers recommend
Key West Coral Reef Snorkel with Mimosas, Margaritas or Rum Punch
CA $75
per adult
84% of travellers recommend
Key West Sunset Sail with Live Music, Drinks and Appetizers!
CA $110
per adult
92% of travellers recommend
Key West Afternoon At The Reef Snorkeling Adventure with Open Bar!
CA $65
per adult
90% of travellers recommend
Uptown - Upper Duval Hotel Deals
Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
The price is CA $243 per night from Aug 24 to Aug 25
CA $243
CA $367 total
Aug 24 - Aug 25
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,662 reviews)
"We really enjoyed our stay. We loved the location, as it was close to the action but also being at the end of the street, felt private still. There were a couple things broken in our room, like the blinds and a light in our room and the water pressure was awful, otherwise I would have given it 5 ..."
Reviewed on Aug. 8, 2025
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street, Key West, FL
The price is CA $328 per night from Sep 9 to Sep 10
CA $328
CA $452 total
Sep 9 - Sep 10
includes taxes & fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,003 reviews)
"Convenient to Duval St, Southern Most Point and, has it’s own beach."
Reviewed on Aug. 6, 2025
Southwinds Motel
1321 Simonton Street, Key West, FL
The price is CA $162 per night from Sep 9 to Sep 10
CA $162
CA $222 total
Sep 9 - Sep 10
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,150 reviews)
"It was a great place to stay"
Reviewed on Aug. 6, 2025
The Southernmost Inn - Adults Only
525 United Street, Key West, FL
The price is CA $136 per night from Aug 17 to Aug 18
CA $136
CA $215 total
Aug 17 - Aug 18
includes taxes & fees
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,146 reviews)
"Love staying here. Have several times now. Staff is always welcoming and friendly. Great location to relax and enjoy the pool. But only block away from the Duval action. Def our goto spot to stay when in key west"
Reviewed on Aug. 7, 2025
Orchid Key Inn - Adults Only
1004 Duval St, Key West, FL
The price is CA $267 per night from Aug 14 to Aug 15
CA $267
CA $301 total
Aug 14 - Aug 15
includes taxes & fees
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
9.8/10 Exceptional! (1,003 reviews)
"Extremely nice hotel. Love the bar and hotel. The staff was great!"
Reviewed on Aug. 8, 2025
Southernmost House
1400 Duval Street, Key West, FL
The price is CA $284 per night from Aug 12 to Aug 13
CA $284
CA $447 total
Aug 12 - Aug 13
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (1,000 reviews)
"Fantastic hotel in a great location. The house has lots of history and kept traditional to the build period. Staff were faultless, helpful and very friendly. The only very small downside which is nothing to do with the hotel is the occasional smell from a nearby sewage pipe outlet which is too close ..."
Reviewed on Aug. 8, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Other neighbourhoods around Uptown - Upper Duval
Old Town Key West
3.5/5(8 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Downtown Key West
If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.
Bahama Village
Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
Key West Historic District
4.5/5(156 area reviews)
Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.
White Street Gallery District
When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.
- Places of interest
- Uptown - Upper Duval Hotels by Star Rating
- Hotels in top Key West neighborhoods
- Uptown - Upper Duval Hotels by Brand
- Other vacations you might like
- Southernmost Point
- South Beach
- Duval Street
- Mallory Square
- Smathers Beach
- Fort Zachary Taylor Historic State Park
- Clarence S. Higgs Memorial Beach Park
- Boca Chica Nude Beach
- Harry S. Truman Little White House
- Florida Keys National Marine Sanctuary
- Key West Lighthouse and Keeper's Quarters Museum
- Florida Keys Eco - Discovery Center
- Mel Fisher Maritime Museum
- Key West Shipwreck Museum
- Fort East Martello Museum and Gallery
Other Hotels near Uptown - Upper Duval, Key West
Uptown - Upper Duval Hotels by Brand
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