Irene Vacation Rentals

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Check prices for these dates

Next weekend
Aug 15 - Aug 17
In two weeks
Aug 22 - Aug 24
In one month
Sep 5 - Sep 7
In two months
Oct 3 - Oct 5

Browse Select Irene Vacation Homes

Beautiful Country Setting mins from Lewis & Clark
Enjoy a serene view of lush green landscapes from this expansive deck.

Beautiful Country Setting mins from Lewis & Clark

9.8 out of 10, Exceptional, (17)
"Lynn is an excellent host! The property is fantastic! Very clean and comfortable with lots of accommodations! Everything you need for a great stay is available! Thank you Lynn!"
Beautiful Country Setting mins from Lewis & Clark
Gavins Point Lakehouse
Enjoy cooking in this well-equipped kitchen with a central island, ample counter space, and cabinets.

Gavins Point Lakehouse

10.0 out of 10, Exceptional, (5)
Gavins Point Lakehouse
The Lake House - Lakeview with 6 bedrooms - Yankton, SD
Relax in style with a pool table and flat-screen TV in this contemporary living space.

The Lake House - Lakeview with 6 bedrooms - Yankton, SD

10.0 out of 10, Exceptional, (58)
"Several years at this location on an annual fishing trip, haven’t looked for any other places since finding this, good stay as always "
The Lake House - Lakeview with 6 bedrooms - Yankton, SD
Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton.
Enjoy outdoor space on the deck with a railing, surrounded by a garden and trees.

Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton.

10.0 out of 10, Exceptional, (7)
"We had 13 people age ranging from 36-2. All had a wonderful time. Hot tub was amazing. The backyard was fun for the kids. Saw some turkeys roosting in the trees. Plenty of toys. Enjoyed our stay."
The price is CA $412
CA $752 total
includes taxes & fees
Aug 10 - Aug 11
Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton.
Charming Lake House within Walking Distance from Lake
Relax in style on this serene patio surrounded by lush greenery, featuring a glass-top table and comfortable wicker chairs with cushions.

Charming Lake House within Walking Distance from Lake

9.6 out of 10, Exceptional, (32)
"Fantastic amenities in a large cabin setting. Comfortable, quiet, spacious, and everything and anything you may need is there. Each evening we were greeted by the resident deer family. The family could spread out if they chose or came together to watch playoff hockey on the big screen TVs. The deck is spacious comfortable with the feel of being in the woods.would highly recommend. "
Charming Lake House within Walking Distance from Lake
Lake property just a few blocks from public beach. Marina a mile away.
Enjoy cooking in this well-equipped kitchen with a bathtub, ceiling fan, and white appliances.

Lake property just a few blocks from public beach. Marina a mile away.

10.0 out of 10, Exceptional, (14)
"Great property, great host."
Lake property just a few blocks from public beach. Marina a mile away.
Haven by the Lake
Enjoy cooking in this well-equipped kitchen with a large island and bar stools, featuring a refrigerator, microwave, gas range, and oven.

Haven by the Lake

10.0 out of 10, Exceptional, (19)
"Comfortable stay close to the lake."
Haven by the Lake
ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18
Enjoy cooking in this well-equipped kitchen with a large island, stainless steel range, and dishwasher.

ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18

9.8 out of 10, Exceptional, (58)
"Everything was well kept and ready to use. "
The price is CA $866
CA $1,205 total
includes taxes & fees
Aug 7 - Aug 8
ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18
Yankton home close to the lake
Enjoy cooking in this well-equipped kitchen with a central island, stove, microwave, and sink.

Yankton home close to the lake

10.0 out of 10, Exceptional, (5)
"This property was a great fit for our family and the property owners were so easy to work with. If we rent again in Yankton, I will stay there again. Nice Neighborhood and it was, very quiet."
Yankton home close to the lake
Retreat near the Lake and State Parks of Yankton
Enjoy cooking in this well-equipped kitchen with a central island, microwave, stove, and sink.

Retreat near the Lake and State Parks of Yankton

9.4 out of 10, Exceptional, (13)
"Nice and roomy to stay. quiet and easy access. will stay again when we get the chance."
Retreat near the Lake and State Parks of Yankton
Scenic Yankton Retreat w/ Fire Pit: 1 Mi to Lake!
Enjoy al fresco dining with a grill and fire pit, surrounded by a lush hillside and stone wall.

Scenic Yankton Retreat w/ Fire Pit: 1 Mi to Lake!

9.6 out of 10, Exceptional, (4)
"This place was perfect! Everything you could possibly need to have a wonderful stay. We loved it and are already planning to go back next year! Thank you!"
Scenic Yankton Retreat w/ Fire Pit: 1 Mi to Lake!
Family-Friendly ‘Lakeview Cottage’ w/ Deck & View
Enjoy a serene outdoor space with a table, chairs, and umbrella, surrounded by lush greenery and a beautiful view of the water and distant landforms.

Family-Friendly ‘Lakeview Cottage’ w/ Deck & View

2.0 star property
9.6 out of 10, Exceptional, (4)
"It was a nice quiet weekend."
Family-Friendly ‘Lakeview Cottage’ w/ Deck & View
Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
Enjoy cooking in this well-equipped kitchen with an oven, microwave, and refrigerator.

Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!

10.0 out of 10, Exceptional, (20)
"Beautiful house. Very cozy. Had a great stay."
The price is CA $866
CA $1,192 total
includes taxes & fees
Aug 6 - Aug 7
Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
'Eagles View' w/ Game Room - Walk to River!
Enjoy a serene outdoor space with a deck, table, and chairs overlooking a lush landscape.

'Eagles View' w/ Game Room - Walk to River!

9.8 out of 10, Exceptional, (8)
"Very clean property in a quiet location. Hosts were very responsive and a great place to bring kids."
'Eagles View' w/ Game Room - Walk to River!
Peaceful Farmhouse with hot tub
Relax in the hot tub on the patio with a serene view of the open field and distant tree line.

Peaceful Farmhouse with hot tub

10.0 out of 10, Exceptional, (3)
"Very nice place, had everything we needed."
Peaceful Farmhouse with hot tub
Yankton Vacation Home w/ Hot Tub & River Views
Relax on the deck with a chair and bench, taking in the serene views of the body of water and distant landscape.

Yankton Vacation Home w/ Hot Tub & River Views

9.6 out of 10, Exceptional, (4)
"Large enough for a great family vacation."
Yankton Vacation Home w/ Hot Tub & River Views
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Irene Hotel Reviews

Holiday Inn Express & Suites Yankton by IHG

Holiday Inn Express & Suites Yankton by IHG

10/10 Excellent
"Bed and piloows were superb"
Robin 2-night trip
Posted 2 days ago
Holiday Inn Express & Suites Yankton by IHG