Title: Book the Best Guthrie SPA Resorts from CA $157 - Spa Hotels in Guthrie, OK | Expedia.ca [Hotels in Guthrie](https://expedia.ca/Guthrie-Hotels.d7494.Travel-Guide-Hotels)[Vacation Rentals in Guthrie](https://expedia.ca/Guthrie-Vacation-Rentals.d7494.Travel-Guide-VacationRentals)[Flights to Guthrie](https://expedia.ca/Cheap-Flights-To-Guthrie.d7494.Travel-Guide-Flights)[Guthrie Car Rentals](https://expedia.ca/Car-Rentals-In-Guthrie.d7494.Car-Rental-Guide)[Guthrie Vacation Packages](https://expedia.ca/Guthrie.d7494.Destination-Travel-Guides) ![Lots of clouds in Guthrie. 3/29/16](https://images.trvl-media.com/place/7494/255393bd-b31c-4691-a662-ced53d634010.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Alice Burghart # Find Spa Hotels in Guthrie, OK from CA $157 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Guthrie Spa Hotels Tonight [Jan 10 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=7494&startDate=2026-01-10&endDate=2026-01-11&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 11 - Jan 12](https://www.expedia.ca/Hotel-Search?regionId=7494&startDate=2026-01-11&endDate=2026-01-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=7494&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=7494&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Guthrie hotels with a spa ![Property grounds](https://images.trvl-media.com/lodging/103000000/102310000/102302700/102302688/15ddb6cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, free WiFi](https://images.trvl-media.com/lodging/103000000/102310000/102302700/102302688/799d6e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/103000000/102310000/102302700/102302688/c0732db0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Room, 1 King Bed](https://images.trvl-media.com/lodging/103000000/102310000/102302700/102302688/0c34dcdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The District Hotel Club and Resorts [](https://www.expedia.ca/Oklahoma-City-Hotels-The-District-Hotel-Club-And-Resorts.h102302688.Hotel-Information) Central Oklahoma City 7.8/10 Good (235 reviews) "Very nice stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen CA $133 CA $157 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Oklahoma-City-Hotels-The-District-Hotel-Club-And-Resorts.h102302688.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/54000000/53800000/53798900/53798807/e802f7be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53800000/53798900/53798807/856302a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/54000000/53800000/53798900/53798807/202dcb4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room | Balcony](https://images.trvl-media.com/lodging/54000000/53800000/53798900/53798807/ae51499b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WangShi China Palace B&B [](https://www.expedia.ca/Oklahoma-City-Hotels-WangShi-China-Palace-Bed-And-Breakfast.h53798807.Hotel-Information) Oklahoma City 9.4/10 Exceptional (107 reviews) "Everything was good and limo service was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) edison CA $312 CA $368 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Oklahoma-City-Hotels-WangShi-China-Palace-Bed-And-Breakfast.h53798807.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-24&endDate=2026-01-25®ionId=7494&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Guthrie Hotel Reviews ![La Quinta Inn & Suites by Wyndham Oklahoma City - NW Expwy](https://images.trvl-media.com/lodging/1000000/170000/165600/165560/7d2f000e_y.jpg) ### La Quinta Inn & Suites by Wyndham Oklahoma City - NW Expwy 10/10 Excellent "Staff was nice. And helpful " [](https://expedia.ca/Oklahoma-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Oklahoma-City-NW-Expwy.h165560.Hotel-Information) ![Holiday Inn Express & Suites Guthrie North Edmond by IHG](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/763ab2db_y.jpg) ### Holiday Inn Express & Suites Guthrie North Edmond by IHG 10/10 Excellent "Great menu, and helpful staff. " [](https://expedia.ca/Guthrie-Hotels-Holiday-Inn-Express-Suites-Guthrie.h2858839.Hotel-Information) ![La Quinta Inn & Suites by Wyndham OKC North - Quail Springs](https://images.trvl-media.com/lodging/2000000/1090000/1088100/1088005/w2000h1499x0y1-cce58d94_y.jpg) ### La Quinta Inn & Suites by Wyndham OKC North - Quail Springs 10/10 Excellent "Clean room.. friendly staff!! Didn’t have to ask for more towels!! " [](https://expedia.ca/Oklahoma-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OKC-North-Quail-Springs.h1088005.Hotel-Information) ![Country Inn & Suites by Radisson, Oklahoma City - Quail Springs, OK](https://images.trvl-media.com/lodging/4000000/3630000/3626800/3626795/e37b306f_y.jpg) ### Country Inn & Suites by Radisson, Oklahoma City - Quail Springs, OK 10/10 Excellent "The room was very large and the beds were comfortable. I would definitely stay here again." [](https://expedia.ca/Oklahoma-City-Hotels-Country-Inn-Suites-By-Radisson.h3626795.Hotel-Information) ![Renaissance Waterford Oklahoma City Hotel](https://images.trvl-media.com/lodging/1000000/30000/23400/23312/bc6a010a_y.jpg) ### Renaissance Waterford Oklahoma City Hotel 10/10 Excellent "Breakfast was good with some healthy options. Room was clean and comfortable." [](https://expedia.ca/Oklahoma-City-Hotels-Renaissance-Waterford-Oklahoma-City-Hotel.h23312.Hotel-Information) ![Holiday Inn Hotel & Suites Oklahoma City North by IHG](https://images.trvl-media.com/lodging/1000000/10000/700/656/e65ee946_y.jpg) ### Holiday Inn Hotel & Suites Oklahoma City North by IHG 10/10 Excellent "." [](https://expedia.ca/Oklahoma-City-Hotels-Holiday-Inn-Hotel-Suites-Oklahoma-City-North.h656.Hotel-Information) ![Baymont by Wyndham Oklahoma City/Quail Springs](https://images.trvl-media.com/lodging/1000000/50000/41300/41248/9faf9e11_y.jpg) ### Baymont by Wyndham Oklahoma City/Quail Springs 10/10 Excellent "Good room and nice hottub" [](https://expedia.ca/Oklahoma-City-Hotels-Baymont-By-Wyndham-Oklahoma-CityQuail-Springs.h41248.Hotel-Information) ## Frequently asked questions ### Which hotels in Guthrie offer the best spa experiences? > The 9.6-rated Dominion Gardens and Hotel provides dedicated treatment rooms for various spa services. Guests frequently comment on the beautiful and amazing rooms, as well as the large showers, which contribute to a relaxing stay. ### How much does a spa hotel in Guthrie cost? ### Is it cheaper to book a spa hotel in Guthrie with flights as part of a package deal? ### Are there any unique spa experiences available in Guthrie? > Serenity Now Spa provides an extensive wellness retreat with a wide array of treatments including facials, massage therapy, body wraps, scrubs, hair and nail care, waxing, and spray tanning. They also offer medical aesthetic services and advanced facial options like V-FR and Prime Préime DermaFacial (Aqua Facial) for skin tightening and rejuvenation, utilising natural and green products. This spa is also expanding to include holistic wellness activities such as yoga, Pilates, personal training, guided meditation, and breath work. > > > Strive Wellness Lounge offers a more medically oriented wellness experience, providing services such as IV therapy, hormone optimisation, weight loss programmes, and a distinctive pelvic floor health treatment designed to improve bladder control and sexual satisfaction. ### How can I save on a spa hotel in Guthrie with Expedia? ### Can I cancel my spa hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [3 Star Hotels in Coyle ](https://www.expedia.ca/3Star-Coyle-Hotels.s30-0-d3000352373.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Langston ](https://www.expedia.ca/5Star-Langston-Hotels.s50-0-d3000453923.Travel-Guide-Filter-Hotels) - [Farmstay in Arcadia ](https://www.expedia.ca/Arcadia-Agritourism.d553248634998834249-aaAgritourism.Travel-Guide-Accommodation) - 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