Find Spa Hotels in Guthrie, OK from CA $157

For exceptional spa experiences in Guthrie, Dominion Gardens and Hotel is a great choice.


The 9.6-rated Dominion Gardens and Hotel provides dedicated treatment rooms for various spa services. Guests frequently comment on the beautiful and amazing rooms, as well as the large showers, which contribute to a relaxing stay.

Enjoy staying in a spa hotel in Guthrie, with plenty of hotels from CA $157 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.

Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it’s wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.

Yes, Guthrie, Oklahoma offers several unique spa and wellness experiences, primarily through Serenity Now Spa and Strive Wellness Lounge.


Serenity Now Spa provides an extensive wellness retreat with a wide array of treatments including facials, massage therapy, body wraps, scrubs, hair and nail care, waxing, and spray tanning. They also offer medical aesthetic services and advanced facial options like V-FR and Prime Préime DermaFacial (Aqua Facial) for skin tightening and rejuvenation, utilising natural and green products. This spa is also expanding to include holistic wellness activities such as yoga, Pilates, personal training, guided meditation, and breath work.


Strive Wellness Lounge offers a more medically oriented wellness experience, providing services such as IV therapy, hormone optimisation, weight loss programmes, and a distinctive pelvic floor health treatment designed to improve bladder control and sexual satisfaction.

Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Guthrie for you.

Find Guthrie spa hotel deals by joining One Key™, Expedia’s free travel rewards program. As a member, you can unlock instant savings with Member Prices when you’re logged in. For a quick weekend retreat, discover last-minute offers.