Title: Book the Best Guthrie SPA Resorts from CA $171 - Spa Hotels in Guthrie, OK | Expedia.ca [Hotels in Guthrie](https://expedia.ca/Guthrie-Hotels.d7494.Travel-Guide-Hotels)[Vacation Rentals in Guthrie](https://expedia.ca/Guthrie-Vacation-Rentals.d7494.Travel-Guide-VacationRentals)[Flights to Guthrie](https://expedia.ca/Cheap-Flights-To-Guthrie.d7494.Travel-Guide-Flights)[Guthrie Car Rentals](https://expedia.ca/Car-Rentals-In-Guthrie.d7494.Car-Rental-Guide)[Guthrie Vacation Packages](https://expedia.ca/Guthrie.d7494.Destination-Travel-Guides) ![Guthrie Clock](https://images.trvl-media.com/place/7494/56f22916-6afc-4818-8c59-de7fe4994107.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7494/56f22916-6afc-4818-8c59-de7fe4994107.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Guthrie Spa Hotels Tonight [Mar 12 - Mar 13](https://www.expedia.ca/Hotel-Search?regionId=7494&startDate=2026-03-12&endDate=2026-03-13&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 13 - Mar 14](https://www.expedia.ca/Hotel-Search?regionId=7494&startDate=2026-03-13&endDate=2026-03-14&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=7494&startDate=2026-03-13&endDate=2026-03-15&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=7494&startDate=2026-03-20&endDate=2026-03-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Guthrie hotels with a spa ![Property grounds](https://images.trvl-media.com/lodging/103000000/102310000/102302700/102302688/15ddb6cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Room, 1 King Bed](https://images.trvl-media.com/lodging/103000000/102310000/102302700/102302688/0c34dcdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, free WiFi](https://images.trvl-media.com/lodging/103000000/102310000/102302700/102302688/799d6e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/103000000/102310000/102302700/102302688/c0732db0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The District Hotel Club and Resorts [](https://www.expedia.ca/Oklahoma-City-Hotels-The-District-Hotel-Club-And-Resorts.h102302688.Hotel-Information) Central Oklahoma City 8.0/10 Very good (262 reviews) - Escape to this hotel with indulgent spa services, seasonal outdoor pool, and modern comforts for a stress-melting wellness retreat. CA $145 CA $171 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Oklahoma-City-Hotels-The-District-Hotel-Club-And-Resorts.h102302688.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/54000000/53800000/53798900/53798807/e802f7be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/54000000/53800000/53798900/53798807/4544eb04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/54000000/53800000/53798900/53798807/202dcb4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room | Balcony](https://images.trvl-media.com/lodging/54000000/53800000/53798900/53798807/ae51499b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WangShi China Palace B&B [](https://www.expedia.ca/Oklahoma-City-Hotels-WangShi-China-Palace-Bed-And-Breakfast.h53798807.Hotel-Information) Oklahoma City 9.4/10 Exceptional (108 reviews) - Tranquil spa retreat at this charming bed & breakfast with sauna, hot tub, and peaceful garden setting. CA $306 CA $360 total includes taxes & fees Apr 7 - Apr 8 [](https://www.expedia.ca/Oklahoma-City-Hotels-WangShi-China-Palace-Bed-And-Breakfast.h53798807.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-26&endDate=2026-03-27®ionId=7494&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Guthrie Pool Breakfast included Hot tub 4 stars 5 stars ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AFFINITY_SPRING_PROMO_7494) ## Top Guthrie Hotel Reviews ![La Quinta Inn & Suites by Wyndham Oklahoma City - NW Expwy](https://images.trvl-media.com/lodging/1000000/170000/165600/165560/a462e17c_y.jpg) ### La Quinta Inn & Suites by Wyndham Oklahoma City - NW Expwy 10/10 Excellent "The staff at check in was excellent. He did a wonderful job explaining everything. He was also very helpful with answering any questions again. I will definitely be staying here again the next time I visit. " [](https://expedia.ca/Oklahoma-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Oklahoma-City-NW-Expwy.h165560.Hotel-Information) ![La Quinta Inn & Suites by Wyndham OKC North - Quail Springs](https://images.trvl-media.com/lodging/2000000/1090000/1088100/1088005/7c627249_y.jpg) ### La Quinta Inn & Suites by Wyndham OKC North - Quail Springs 10/10 Excellent "Room was clean and plenty of towels available" [](https://expedia.ca/Oklahoma-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OKC-North-Quail-Springs.h1088005.Hotel-Information) ![Renaissance Waterford Oklahoma City Hotel](https://images.trvl-media.com/lodging/1000000/30000/23400/23312/bc6a010a_y.jpg) ### Renaissance Waterford Oklahoma City Hotel 10/10 Excellent "Clean room" [](https://expedia.ca/Oklahoma-City-Hotels-Renaissance-Waterford-Oklahoma-City-Hotel.h23312.Hotel-Information) ![Holiday Inn Hotel & Suites Oklahoma City North by IHG](https://images.trvl-media.com/lodging/1000000/10000/700/656/d9f50912_y.jpg) ### Holiday Inn Hotel & Suites Oklahoma City North by IHG 2/10 Terrible "Dark unsafe parking. Toilet didnt work" [](https://expedia.ca/Oklahoma-City-Hotels-Holiday-Inn-Hotel-Suites-Oklahoma-City-North.h656.Hotel-Information) ![Country Inn & Suites by Radisson, Oklahoma City - Quail Springs, OK](https://images.trvl-media.com/lodging/4000000/3630000/3626800/3626795/e37b306f_y.jpg) ### Country Inn & Suites by Radisson, Oklahoma City - Quail Springs, OK 10/10 Excellent "Nice" [](https://expedia.ca/Oklahoma-City-Hotels-Country-Inn-Suites-By-Radisson.h3626795.Hotel-Information) ![Holiday Inn Express & Suites Guthrie North Edmond by IHG](https://images.trvl-media.com/lodging/3000000/2860000/2858900/2858839/f3debf7c_y.jpg) ### Holiday Inn Express & Suites Guthrie North Edmond by IHG 10/10 Excellent "Staff cheerful, Breakfast good variety, Room clean with plenty of space, Room Temperature easy to adjust. " [](https://expedia.ca/Guthrie-Hotels-Holiday-Inn-Express-Suites-Guthrie.h2858839.Hotel-Information) ## Frequently asked questions ### Which hotels in Guthrie offer the best spa experiences? > The 9.6-rated Dominion Gardens and Hotel provides dedicated treatment rooms for various spa services. Guests frequently comment on the beautiful and amazing rooms, as well as the large showers, which contribute to a relaxing stay. ### How much does a spa hotel in Guthrie cost? ### Is it cheaper to book a spa hotel in Guthrie with flights as part of a package deal? ### Are there any unique spa experiences available in Guthrie? > Serenity Now Spa provides an extensive wellness retreat with a wide array of treatments including facials, massage therapy, body wraps, scrubs, hair and nail care, waxing, and spray tanning. They also offer medical aesthetic services and advanced facial options like V-FR and Prime Préime DermaFacial (Aqua Facial) for skin tightening and rejuvenation, utilising natural and green products. This spa is also expanding to include holistic wellness activities such as yoga, Pilates, personal training, guided meditation, and breath work. > > > Strive Wellness Lounge offers a more medically oriented wellness experience, providing services such as IV therapy, hormone optimisation, weight loss programmes, and a distinctive pelvic floor health treatment designed to improve bladder control and sexual satisfaction. ### How can I save on a spa hotel in Guthrie with Expedia? ### Can I cancel my spa hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [3 Star Hotels in Coyle ](https://www.expedia.ca/3Star-Coyle-Hotels.s30-0-d3000352373.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Langston ](https://www.expedia.ca/5Star-Langston-Hotels.s50-0-d3000453923.Travel-Guide-Filter-Hotels) - [Farmstay in Arcadia ](https://www.expedia.ca/Arcadia-Agritourism.d553248634998834249-aaAgritourism.Travel-Guide-Accommodation) - 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