Title: Guadalupe Vacation Home Rentals from CA $91: Search Top Private Vacation Homes for Rent | Expedia.ca [Hotels in Guadalupe](https://expedia.ca/Guadalupe-Hotels.d6204275.Travel-Guide-Hotels)[Vacation Rentals in Guadalupe](https://expedia.ca/Guadalupe-Vacation-Rentals.d6204275.Travel-Guide-VacationRentals)[Flights to Guadalupe](https://expedia.ca/Cheap-Flights-To-Guadalupe.d6204275.Travel-Guide-Flights)[Guadalupe Car Rentals](https://expedia.ca/Car-Rentals-In-Guadalupe.d6204275.Car-Rental-Guide)[Guadalupe Vacation Packages](https://expedia.ca/Guadalupe.d6204275.Destination-Travel-Guides) ![Drying seagrass and kelp on isthmus of sand between Pacific ocean and the Santa Maria river at the Rancho Guadalupe Sand Dunes Preserve on the central coast of California United States](https://images.trvl-media.com/place/6204275/c9247d8f-6401-4e4c-b1ac-8339590a517e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6204275/c9247d8f-6401-4e4c-b1ac-8339590a517e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6204275&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6204275&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=6204275&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=6204275&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Guadalupe ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3836h2557x4y3-ba31f59e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3837h2557x3y3-42b8e782.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3837h2557x3y3-cfdd8975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/e01e83cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Santa Maria [](https://www.expedia.ca/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) Santa Maria 8.8/10 Excellent (61 reviews) "Food was really good!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephenie CA $155 CA $174 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) ![2 Queen Designer](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/a4111cf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Designer](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/5b767704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort ADA Suite - 112 | Living area](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/8b75e1b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Studio Suite - 114](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/9a46f872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Avanti [](https://www.expedia.ca/Santa-Maria-Hotels-Hotel-Avanti.h102791710.Hotel-Information) Santa Maria 9.0/10 Wonderful (298 reviews) "The rooms were surprisingly nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mario CA $124 CA $139 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Santa-Maria-Hotels-Hotel-Avanti.h102791710.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/373b886f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/0396337b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/w1113h629x0y7-b1650579.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Santa Maria Inn [](https://www.expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) Santa Maria 8.4/10 Very good (1,928 reviews) "Very comfortable stay… staff very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dena CA $110 CA $123 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/4cda8af4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/ef92de8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/8d75e25e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/e16ece78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Casa Grande Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Casa-Grande-Inn.h23008.Hotel-Information) Pismo Beach 8.8/10 Excellent (1,197 reviews) "Convenient location; close to shopping and enjoyed the decor" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Loretta CA $115 CA $131 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Casa-Grande-Inn.h23008.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/9593cdf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/2fcf8a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/44c3350f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/872d0d33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spyglass Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) Pismo Beach 9.0/10 Wonderful (1,408 reviews) "Perfect stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nishant CA $162 CA $185 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/0d7c35a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/0f7b2fce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Refrigerator | Bathroom](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/46a3a6b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/d2f85309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Santa Maria [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Santa-Maria.h38229980.Hotel-Information) Santa Maria 9.4/10 Exceptional (1,005 reviews) "The rooms, beds, and bathrooms were super clean, the breakfast was excellent, and the staff were very attentive. My family and I had a wonderful stay. If I had to travel to Santa Maria again, I would choose the same hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcos CA $164 CA $185 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Santa-Maria.h38229980.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/3beb869e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony Suite](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/9b61e0f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/1f7b8b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite | Living area](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/1e162862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Edgewater Inn And Suites [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) Downtown Pismo Beach 8.6/10 Excellent (2,669 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Serena CA $122 CA $139 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/598df5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/4ed108b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/2c732443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/33b4a0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Santa Maria [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Radisson-Hotel-Santa-Maria.h433636.Hotel-Information) Santa Maria 7.4/10 Good (1,331 reviews) "very nice Hotel is getting renovated got an upgradde to a renovated room beds are supper confy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teodoro CA $135 CA $152 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Radisson-Hotel-Santa-Maria.h433636.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/010bbafb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/1992b2a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/bdf372cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/c25c8ed8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oxford Suites Pismo Beach [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) 855634304 9.0/10 Wonderful (1,768 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Agnieszka CA $134 CA $170 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/b40c24d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/5a31bb9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner served; American cuisine, ocean views ](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/be43feea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/c2cc9676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SeaCrest OceanFront Hotel [](https://www.expedia.ca/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) Pismo Beach 9.2/10 Wonderful (1,605 reviews) "Nice property we would stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hugo CA $204 CA $234 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/15000000/14910000/14900200/14900166/f443b7f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/15000000/14910000/14900200/14900166/444668fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/15000000/14910000/14900200/14900166/e1ebe5d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/15000000/14910000/14900200/14900166/500d204e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Palms Motel [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Ocean-Palms-Motel.h14900166.Hotel-Information) Downtown Pismo Beach 9.0/10 Wonderful (1,000 reviews) " Clean room and helpful staff. Walkable distance to Pismo beach and restaurant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vinayaka CA $93 CA $139 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Ocean-Palms-Motel.h14900166.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9800/9742/w3900h2589x0y3-abdabefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/9800/9742/0cd3d849.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/10000/9800/9742/892a5c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![King Bed Pier View Room | View from room](https://images.trvl-media.com/lodging/1000000/10000/9800/9742/2de0ba5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Shore Cliff Hotel [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Shore-Cliff-Hotel.h9742.Hotel-Information) Pismo Beach 9.2/10 Wonderful (1,499 reviews) "Best hotel in pismo breath taking ocean view" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) aline CA $201 CA $285 total includes taxes & fees Mar 4 - Mar 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Shore-Cliff-Hotel.h9742.Hotel-Information) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/900000/899300/899217/fc58c145.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/900000/899300/899217/0acd9703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/900000/899300/899217/faaa4952.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/899300/899217/14724fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Luis Obispo, CA - South [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Motel-6-San-Luis-Obispo.h899217.Hotel-Information) San Luis Obispo 8.4/10 Very good (1,047 reviews) "Staff was friendly and the room was nice and clean. The price is also reasonable. Will definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ely Harvey CA $104 CA $118 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Motel-6-San-Luis-Obispo.h899217.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2040000/2039900/2039849/e08330df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2040000/2039900/2039849/638e2e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2040000/2039900/2039849/6c756f86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Television](https://images.trvl-media.com/lodging/3000000/2040000/2039900/2039849/ce2a6de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Solaire Inn & Suites [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Solaire-Inn-Suites.h2039849.Hotel-Information) Santa Maria 8.2/10 Very good (1,009 reviews) "very clean room, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Antonio CA $80 CA $91 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Solaire-Inn-Suites.h2039849.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/160000/151000/150921/a9c907e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/160000/151000/150921/41389416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/1000000/160000/151000/150921/4faaa377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/160000/151000/150921/662d6b8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage Inn By The Sea [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Cottage-Inn-By-The-Sea.h150921.Hotel-Information) Pismo Beach 9.0/10 Wonderful (1,209 reviews) "Very clean and comfortable, located within walking distance of beach and resturants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa CA $196 CA $225 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Cottage-Inn-By-The-Sea.h150921.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/fda3cb7d_edited_c5f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6:00 AM to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/82a54fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/w5755h3835x5y5-f126bb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/1170bb3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Big America [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Plus-Big-America.h15345.Hotel-Information) Santa Maria 8.8/10 Excellent (1,001 reviews) "Great rooms and amenities." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $148 CA $167 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Plus-Big-America.h15345.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3300/3289/d5680736.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/3300/3289/e533667d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Accessible (Hearing)](https://images.trvl-media.com/lodging/1000000/10000/3300/3289/435dec11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3300/3289/194ac9d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton Lompoc Central Coast [](https://www.expedia.ca/Santa-Barbara-Hotels-Embassy-Suites-By-Hilton-Lompoc-Central-Coast.h3289.Hotel-Information) Lompoc 8.4/10 Very good (1,002 reviews) "Always a great stay! Staff are so kind and very helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darcel CA $162 CA $183 total includes taxes & fees Feb 21 - Feb 22 [](https://www.expedia.ca/Santa-Barbara-Hotels-Embassy-Suites-By-Hilton-Lompoc-Central-Coast.h3289.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/14000000/13280000/13279100/13279003/b5875520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/14000000/13280000/13279100/13279003/67a8bb73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13280000/13279100/13279003/f3c16650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13280000/13279100/13279003/8c360ac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Arroyo Grande/Pismo Beach [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Pismo-View-Inn.h13279003.Hotel-Information) Arroyo Grande 8.4/10 Very good (941 reviews) "Great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dustin CA $96 CA $123 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Pismo-View-Inn.h13279003.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/3000000/2480000/2470300/2470266/613cd319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/3000000/2480000/2470300/2470266/30f082ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2480000/2470300/2470266/w5755h3835x5y5-e8cc3c60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2480000/2470300/2470266/cda7e9cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Arroyo Grande/Pismo Beach Area, CA [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Arroyo-GrandePismo-Beach-Area.h2470266.Hotel-Information) Arroyo Grande 8.0/10 Very good (1,005 reviews) " Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey T. CA $126 CA $143 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Arroyo-GrandePismo-Beach-Area.h2470266.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/dea8ddbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/f7fb843a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/1d10b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/9fba6166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Agrarian Hotel, BW Signature Collection [](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) Arroyo Grande 9.6/10 Exceptional (1,003 reviews) "Very nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chritine CA $179 CA $204 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-17&endDate=2026-02-18®ionId=6204275&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=Guadalupe%2C+California%2C+United+States+of+America®ionId=6204275&latLong=34.941611%2C-120.617781&adults=2&startDate=2026-05-04&d1=2026-05-04&endDate=2026-05-07&d2=2026-05-07&lodging=APART_HOTEL) Condos [](https://www.expedia.ca/Hotel-Search?destination=Guadalupe%2C+California%2C+United+States+of+America®ionId=6204275&latLong=34.941611%2C-120.617781&adults=2&startDate=2026-05-04&d1=2026-05-04&endDate=2026-05-07&d2=2026-05-07&lodging=CONDO) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Guadalupe%2C+California%2C+United+States+of+America®ionId=6204275&latLong=34.941611%2C-120.617781&adults=2&startDate=2026-05-04&d1=2026-05-04&endDate=2026-05-07&d2=2026-05-07&lodging=VACATION_HOME) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Guadalupe%2C+California%2C+United+States+of+America®ionId=6204275&latLong=34.941611%2C-120.617781&adults=2&startDate=2026-05-04&d1=2026-05-04&endDate=2026-05-07&d2=2026-05-07&lodging=APARTMENT) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Guadalupe%2C+California%2C+United+States+of+America®ionId=6204275&latLong=34.941611%2C-120.617781&adults=2&startDate=2026-05-04&d1=2026-05-04&endDate=2026-05-07&d2=2026-05-07&lodging=COTTAGE) Villas [](https://www.expedia.ca/Hotel-Search?destination=Guadalupe%2C+California%2C+United+States+of+America®ionId=6204275&latLong=34.941611%2C-120.617781&adults=2&startDate=2026-05-04&d1=2026-05-04&endDate=2026-05-07&d2=2026-05-07&lodging=VILLA) Cabins [](https://www.expedia.ca/Hotel-Search?destination=Guadalupe%2C+California%2C+United+States+of+America®ionId=6204275&latLong=34.941611%2C-120.617781&adults=2&startDate=2026-05-04&d1=2026-05-04&endDate=2026-05-07&d2=2026-05-07&lodging=CABIN) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGuadalupe-Private-Vacation-Homes.d6204275-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGuadalupe-Private-Vacation-Homes.d6204275-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Guadalupe Hotel Reviews ![Inn at Avila Beach](https://images.trvl-media.com/lodging/1000000/880000/876400/876307/c50d88f2_y.jpg) ### Inn at Avila Beach 10/10 Excellent "Very nice location" [](https://expedia.ca/Avila-Beach-Hotels-Inn-At-Avila-Beach.h876307.Hotel-Information) ![Hilton Vacation Club San Luis Bay Avila Beach](https://images.trvl-media.com/lodging/1000000/40000/34500/34450/b5500300_y.jpg) ### Hilton Vacation Club San Luis Bay Avila Beach 10/10 Excellent "great room, nice hot tub, wonderful ocean views, nice short walk to restaurants and beach" [](https://expedia.ca/Avila-Beach-Hotels-San-Luis-Bay-Inn.h34450.Hotel-Information) ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/w3000h1999x0y0-15b2e131_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "The staff were excellent. The views were amazing " [](https://expedia.ca/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Historic Santa Maria Inn](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c_y.jpg) ### Historic Santa Maria Inn 10/10 Excellent "Great size room and very clean " [](https://expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Motel 6 Santa Maria, CA - North](https://images.trvl-media.com/lodging/1000000/1000000/996400/996393/5265532a_y.jpg) ### Motel 6 Santa Maria, CA - North 10/10 Excellent "Great place to stay" [](https://expedia.ca/San-Luis-Obispo-Hotels-Motel-6-Santa-Maria.h996393.Hotel-Information) ![Spyglass Inn](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/44c3350f_y.jpg) ### Spyglass Inn 10/10 Excellent "The room was perfect, because scenery. We enjoyed the fire pits & the s’more kit available at the front desk. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) ![Inn at the Cove](https://images.trvl-media.com/lodging/1000000/20000/15400/15382/b6db59c4_y.jpg) ### Inn at the Cove 10/10 Excellent "Beautiful hotel, nice staff, decent breakfast, breathtaking views of ocean. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Inn-At-The-Cove.h15382.Hotel-Information) ![Hotel Calle Joaquin](https://images.trvl-media.com/lodging/1000000/900000/891200/891157/d2fc94ff_y.jpg) ### Hotel Calle Joaquin 10/10 Excellent "Yes very clean" [](https://expedia.ca/San-Luis-Obispo-Hotels-Rose-Garden-Inn-San-Luis-Obispo.h891157.Hotel-Information) ![Hilton Garden Inn San Luis Obispo/Pismo Beach](https://images.trvl-media.com/lodging/2000000/1620000/1619200/1619196/2231ae59_y.jpg) ### Hilton Garden Inn San Luis Obispo/Pismo Beach 10/10 Excellent "Very accommodating staffs" [](https://expedia.ca/San-Luis-Obispo-Hotels-Hilton-Garden-Inn-San-Luis-Obispo-Pismo-Beach.h1619196.Hotel-Information) ## Find out more about Guadalupe ## Guadalupe Vacation Homes information | Number of reviews | 23,944 | | ----------------- | ------------------ | | Accommodation | 424 Vacation Homes | | Lowest Price | CA $91 | | Highest Price | CA $285 | ## Explore a world of travel with Expedia - Lodging - Flights - 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