Default HTG hotel image

Hotels in Enterprise, Des Moines

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Enterprise hotels

A swimming pool with four lounge chairs and a view of trees through large windows.

1. Holiday Inn Express Des Moines Ankeny by IHG

Holiday Inn Express Des Moines Ankeny by IHG
2.5 star property
5.6 km from Enterprise
9.4 out of 10, Exceptional, (370 reviews)
"was a great location for all of our needs. felt very safe in the area would definitely stay there again"
United States
gary
The price is CA $135
CA $152 total
includes taxes & fees
Nov 6 - Nov 7
Holiday Inn Express Des Moines Ankeny by IHG
An outdoor patio area with wooden beams and string lights, furnished with chairs and tables, and a stone wall backdrop.

2. Best Western Premier Des Moines-Ankeny Hotel

Best Western Premier Des Moines-Ankeny Hotel
3.0 star property
4.6 km from Enterprise
9.0 out of 10, Wonderful, (953 reviews)
"The room was clean, staff was friendly, and they had many options for breakfast. This hotel was close to shopping, restaurants, and a quick drive to Ames or Des Moines. We will stay here again!"
United States
Nicholas
The price is CA $114
CA $128 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Premier Des Moines-Ankeny Hotel
A La Quinta hotel with a modern design, featuring a prominent sign, a covered entrance, and a brick facade.

3. La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
3.0 star property
4.6 km from Enterprise
9.2 out of 10, Wonderful, (1,054 reviews)
"Clean hotel, friendly staff"
United States
Todd
The price is CA $119
CA $134 total
includes taxes & fees
Oct 18 - Oct 19
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
A hotel room with two beds, a desk with a computer, a TV, and artwork on the wall.

4. Sleep Inn & Suites Ankeny - Des Moines

Sleep Inn & Suites Ankeny - Des Moines
2.5 star property
4.7 km from Enterprise
9.2 out of 10, Wonderful, (982 reviews)
"Well appointed hotel & clean"
United States
Dawn
The price is CA $133
CA $149 total
includes taxes & fees
Oct 18 - Oct 19
Sleep Inn & Suites Ankeny - Des Moines
A hotel exterior with a stone fire feature, outdoor seating, and a curved building facade.

5. Courtyard Marriott Ankeny

Courtyard Marriott Ankeny
3.0 star property
4.4 km from Enterprise
8.8 out of 10, Excellent, (636 reviews)
"The staff was super friendly and helpful!"
United States
Kendra
The price is CA $139
CA $156 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard Marriott Ankeny
An outdoor patio with a round table and chairs, a view of a lake, and a grassy area with trees.

6. Country Inn & Suites by Radisson, Ankeny - Des Moines

Country Inn & Suites by Radisson, Ankeny - Des Moines
2.5 star property
4.7 km from Enterprise
8.4 out of 10, Very good, (1,001 reviews)
"the bed was soooo comfy! Will stay there again!"
United States
laura
The price is CA $124
CA $139 total
includes taxes & fees
Nov 2 - Nov 3
Country Inn & Suites by Radisson, Ankeny - Des Moines
A hotel lobby with a reception desk, seating area with a sofa and chairs, a coffee station, and a dining area.

7. Comfort Inn & Suites Ankeny - Des Moines

Comfort Inn & Suites Ankeny - Des Moines
2.5 star property
4.2 km from Enterprise
8.8 out of 10, Excellent, (769 reviews)
"Great stay!"
United States
Christopher
The price is CA $120
CA $134 total
includes taxes & fees
Nov 12 - Nov 13
Comfort Inn & Suites Ankeny - Des Moines
Room

8. My Place Hotel - Ankeny/ Des Moines, IA

My Place Hotel - Ankeny/ Des Moines, IA
3.0 star property
4.6 km from Enterprise
9.0 out of 10, Wonderful, (848 reviews)
"Very nice place to stay"
United States
Edwin
The price is CA $121
CA $142 total
includes taxes & fees
Oct 15 - Oct 16
My Place Hotel - Ankeny/ Des Moines, IA
An indoor swimming pool with wooden ceiling beams, tiled walls, and a clear view of the outside through large windows.

9. AmericInn by Wyndham Ankeny/Des Moines

AmericInn by Wyndham Ankeny/Des Moines
3.0 star property
4.6 km from Enterprise
8.0 out of 10, Very good, (955 reviews)
"We enjoyed our stay"
United States
Leslie
The price is CA $114
CA $128 total
includes taxes & fees
Oct 18 - Oct 19
AmericInn by Wyndham Ankeny/Des Moines
A modern lounge area with a central table, seating arrangements, and a decorative ceiling piece.

10. Hampton Inn & Suites Ankeny

Hampton Inn & Suites Ankeny
2.5 star property
5.3 km from Enterprise
8.8 out of 10, Excellent, (516 reviews)
"We have come back to this hotel several times as it’s always clean, spacious rooms, great staff, & a good breakfast!"
United States
Cara
The price is CA $156
CA $175 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites Ankeny
An outdoor patio area with a grill, seating, and string lights.

11. Homewood Suites By Hilton Ankeny

Homewood Suites By Hilton Ankeny
3.0 star property
4.5 km from Enterprise
9.0 out of 10, Wonderful, (641 reviews)
"Excellent stay!! Staff was exceptional welcoming."
United States
Judy
The price is CA $168
CA $189 total
includes taxes & fees
Oct 18 - Oct 19
Homewood Suites By Hilton Ankeny
A hotel lobby with a tiled floor, a reception desk, a green wall, and a door leading to a pool area.

12. Econo Lodge Ankeny - Des Moines

Econo Lodge Ankeny - Des Moines
2.0 star property
4.7 km from Enterprise
8.2 out of 10, Very good, (863 reviews)
"Very nice staff and clean rooms"
United States
Teri
The price is CA $95
CA $106 total
includes taxes & fees
Nov 4 - Nov 5
Econo Lodge Ankeny - Des Moines
An indoor swimming pool with clear water, tiled walls, and a no diving sign.

13. La Quinta by Wyndham Altoona Des Moines

La Quinta by Wyndham Altoona Des Moines
3.0 star property
8.7 km from Enterprise
9.0 out of 10, Wonderful, (1,348 reviews)
"The breakfast was delicious they offered hot & cold food and they have a small bar/lounge on site that was nice"
United States
Michael
The price is CA $121
CA $135 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta by Wyndham Altoona Des Moines
A modern bar area with a long counter, multiple bar stools, and hanging pendant lights.

14. Hampton Inn & Suites Altoona-Des Moines

Hampton Inn & Suites Altoona-Des Moines
2.5 star property
9.1 km from Enterprise
9.2 out of 10, Wonderful, (740 reviews)
"Very clean and updated, friendly staff, great breakfast options, easy location off the highway"
United States
Christy
The price is CA $157
CA $175 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites Altoona-Des Moines
A hotel room with two beds, a nightstand with a phone, and a view of autumn foliage through large windows.

15. Quality Inn & Suites Ankeny - Des Moines

Quality Inn & Suites Ankeny - Des Moines
2.5 star property
4.2 km from Enterprise
7.6 out of 10, Good, (445 reviews)
"Helpful staff, decent breakfast"
United States
Edward
The price is CA $92
CA $103 total
includes taxes & fees
Nov 4 - Nov 5
Quality Inn & Suites Ankeny - Des Moines
A modern kitchen with a bar area, wooden cabinets, and a large window.

16. Tru By Hilton Ankeny

Tru By Hilton Ankeny
2.5 star property
7.4 km from Enterprise
9.0 out of 10, Wonderful, (223 reviews)
"Great location! Staff were very friendly and lobby and rooms were very clean. Will stay here again next time I return to Ankney."
United States
Shauna
The price is CA $144
CA $162 total
includes taxes & fees
Oct 18 - Oct 19
Tru By Hilton Ankeny
A modern outdoor seating area with sofas and tables, overlooking a body of water and a distant building.

17. Hyatt Place Altoona/Des Moines

Hyatt Place Altoona/Des Moines
3.0 star property
8.8 km from Enterprise
9.4 out of 10, Exceptional, (934 reviews)
"It was very clean, nice updated rooms and perfect for a family!!!"
United States
Robert
The price is CA $181
CA $203 total
includes taxes & fees
Oct 18 - Oct 19
Hyatt Place Altoona/Des Moines
A living room with two dark leather sofas, a white coffee table, and a stone fireplace.

18. Super 8 by Wyndham Ankeny/Des Moines Area

Super 8 by Wyndham Ankeny/Des Moines Area
2.0 star property
4.2 km from Enterprise
7.0 out of 10, Good, (695 reviews)
"No complaints, the hotel was clean and quiet."
United States
Mark
The price is CA $93
CA $104 total
includes taxes & fees
Nov 1 - Nov 2
Super 8 by Wyndham Ankeny/Des Moines Area
A reception area with a wooden wall, a reception desk, and seating with red chairs.

19. Comfort Inn Altoona-Des Moines

Comfort Inn Altoona-Des Moines
2.5 star property
8.9 km from Enterprise
8.8 out of 10, Excellent, (545 reviews)
"Thank you so much"
United States
Apajok
The price is CA $108
CA $121 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn Altoona-Des Moines
A coffee station with two espresso machines and a display of coffee cups and pods.

20. Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG
2.5 star property
9.2 km from Enterprise
9.0 out of 10, Wonderful, (835 reviews)
"The stay was nice, beds were comfortable."
United States
rick
The price is CA $138
CA $155 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Enterprise

Find the best Enterprise areas and neighborhoods for the activities you enjoy most.
The entrance to the Greater Des Moines Botanical Garden with a large dome structure in the background.

Downtown Des Moines

Downtown Des Moines boasts corporate campuses, fine dining, and unique retail destinations. Explore the Pappajohn Sculpture Park, and enjoy easy access to DART transit and skywalk connections.
A sign reading "Historic East Village" with a clear blue sky and clouds in the background.

Historic East Village

Directly east of Downtown Des Moines, this nationally recognized historic district boasts the Iowa State Capitol complex, State of Iowa Historical Museum, and Des Moines Botanical Gardens. Explore eateries, boutique shops, and loft-style housing in its charming structures.
A city skyline at night with illuminated buildings and a prominent tower.
Photo by Ryan Brohm
Open Photo by Ryan Brohm

Court District

Court District is known for its ample dining options, and you can make a stop by Science Center of Iowa and Principal Park while in the area.
The exterior and interior of Mars Cafe, featuring a brick facade, large windows, and a red interior with hanging lights and artwork.
Photo by Eric Mondres
Open Photo by Eric Mondres

Drake

If you're spending some time in Drake, Knapp Center and Des Moines Community Playhouse are top sights worth seeing.
A city skyline at dusk with illuminated buildings, a bridge, and a river.

Beaverdale

If you're looking for some top things to see and do in Beaverdale and surrounding area, you can visit Merle Hay Mall and Knapp Center.

Top Enterprise Hotel Reviews

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

10/10 Excellent
"clean rooms good location friendly staff"
Marshall 1-night trip
Posted 4 hours ago
Hotel Fort Des Moines, Curio Collection by Hilton

Frequently asked questions

When is the best time to go to Enterprise?
The best times to visit Enterprise are during the late spring (May to early June) and early autumn (September to October).

During these periods, the weather is pleasantly mild, making it ideal for exploring the outdoor attractions. You'll find comfortable temperatures for walking around the town centre, visiting the local parks, or enjoying a leisurely afternoon at the Enterprise Farmers Market. These months also avoid the peak summer crowds and the colder winter conditions, offering a more relaxed experience.

For those interested in outdoor activities like hiking or cycling, late spring brings blossoming flowers and lush greenery, while early autumn offers beautiful foliage colours.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Enterprise hotel for you.
How much is the nightly rate at a Enterprise hotel?
Hotel prices in Enterprise often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia