A large lake surrounded by dense forests.

Hotels in Downtown, Seneca

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Check prices for these dates

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

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Our top choices for Downtown hotels

A poolside area with outdoor seating and a view of a lake and forested hills.

1. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (288 reviews)
"Excellent in every way!"
United States
Bonnie
The price is CA $168
CA $185 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

2. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
1.7 km from Downtown
8.4 out of 10, Very good, (696 reviews)
"update rooms"
United States
Valerie
The price is CA $131
CA $144 total
includes taxes & fees
Oct 28 - Oct 29
Best Western Seneca-Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.

3. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
2.2 km from Downtown
9.2 out of 10, Wonderful, (762 reviews)
"Room was clean and staff was friendly and helpful."
United States
Sasha
The price is CA $190
CA $209 total
includes taxes & fees
Nov 23 - Nov 24
Hampton Inn & Suites Seneca-Clemson Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.

4. Quality Inn Seneca US-123

Quality Inn Seneca US-123
2.5 star property
3.8 km from Downtown
8.0 out of 10, Very good, (765 reviews)
"Clean rooms clean parking area nice staff all good"
United States
Barry
The price is CA $118
CA $139 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Seneca US-123
An outdoor patio area with a fire pit, seating, and string lights.

5. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
8.4 km from Downtown
9.2 out of 10, Wonderful, (900 reviews)
"Great stay!"
United States
Melissa
The price is CA $142
CA $157 total
includes taxes & fees
Nov 19 - Nov 20
Tru by Hilton Seneca Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.

6. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
3.1 km from Downtown
6.8 out of 10, (791 reviews)
"Staff were nice and accommodating"
United States
Rosario
The price is CA $104
CA $114 total
includes taxes & fees
Oct 28 - Oct 29
Days Inn by Wyndham Seneca / Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

7. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,005 reviews)
"Friendly front desk and bar staff. We had a really nice overnight stay."
United States
Sherry
The price is CA $153
CA $189 total
includes taxes & fees
Oct 27 - Oct 28
Lakeside Lodge Clemson
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

8. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.0 out of 10, Very good, (1,006 reviews)
"Great place to stay while visiting your kids at Clemson!"
United States
Angela
The price is CA $148
CA $164 total
includes taxes & fees
Oct 29 - Oct 30
Best Western Plus Clemson Hotel & Conference Center
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

9. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
10.1 km from Downtown
9.6 out of 10, Exceptional, (656 reviews)
"Very conveniently located to Clemson and well maintained. We enjoyed having an afternoon beverage at the bar and grabbing a quick bite to eat in the morning. Hallways were quiet and I appreciated the bathroom amenities and robes too. I would definitely recommend staying here."
United States
Amy
The price is CA $208
CA $230 total
includes taxes & fees
Nov 3 - Nov 4
The Abernathy of Clemson
A modern kitchen with a microwave, coffee maker, and bar stools.

10. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.4 out of 10, Very good, (1,007 reviews)
"Updated room and friendly staff."
United States
Sherie
The price is CA $148
CA $164 total
includes taxes & fees
Nov 15 - Nov 16
Comfort Inn & Suites Clemson - University Area
A golf course with a water body, trees, and a distant view of a bridge.

11. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (1,004 reviews)
"Great property!"
United States
Lilllian
The price is CA $209
CA $232 total
includes taxes & fees
Oct 27 - Oct 28
Clemson University's James F. Martin Inn
A modern bar area with a menu board, bar stools, and a countertop with various items.

12. Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
12.9 km from Downtown
9.0 out of 10, Wonderful, (591 reviews)
"The staff were so friendly and accommodating. The property was very clean and room was spacious."
United States
kim
The price is CA $145
CA $160 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard Marriott Clemson
A modern kitchen area with a bar counter and seating.

13. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
9.8 km from Downtown
8.8 out of 10, Excellent, (651 reviews)
"Staff was great especially Crystal. Breakfast was fine. A little hidden by trees so watch out or you could miss entrance. Also, driveway just a little steep to get into lot but once there everything was fine. "
United States
Blaise
The price is CA $136
CA $151 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn Clemson-University Area
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

14. Inn @ Clemson

Inn @ Clemson
2.5 star property
11.6 km from Downtown
8.0 out of 10, Very good, (1,005 reviews)
"Clean room, comfortable beds, good breakfast, great price!"
United States
Kristi
The price is CA $101
CA $112 total
includes taxes & fees
Oct 27 - Oct 28
Inn @ Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

15. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (115 reviews)
"My wife and I enjoyed our stay here. 10/10 experience."
United States
Winston
The price is CA $130
CA $204 total
includes taxes & fees
Nov 3 - Nov 4
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

16. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
12.4 km from Downtown
8.8 out of 10, Excellent, (998 reviews)
"Wonderful place to stay."
United States
John
The price is CA $181
CA $201 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Clemson by IHG
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

17. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
12.5 km from Downtown
6.8 out of 10, (237 reviews)
"While the hotel is close to Clemson, the property/ rooms were GROSS!! The bathroom had been wiped down, but whoever cleaned it missed the soap and shampoo left up top on the rim. The AC smelt so strongly of mildew/ mold that we could NOT turn it on. The whole room smelled like wet towels"
United States
Stephanie
The price is CA $112
CA $125 total
includes taxes & fees
Oct 29 - Oct 30
Days Inn by Wyndham Clemson
A kitchen with a coffee maker, microwave, and refrigerator.

18. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
12.8 km from Downtown
7.6 out of 10, Good, (198 reviews)
"Good value for the price. Bed was comfortable and the price was good"
United States
Richard
The price is CA $112
CA $125 total
includes taxes & fees
Nov 24 - Nov 25
Rodeway Inn & Suites Walhalla
A hotel lobby with a reception desk, seating area, and a view of the street outside.

19. Econo Lodge Clemson - University Area

Econo Lodge Clemson - University Area
2.0 star property
13.1 km from Downtown
7.2 out of 10, Good, (160 reviews)
"Good location . Good price. Nice and quiet. Unusually good tv show choices. (Much better than last 4 or 5 hotels that I stayed at!)"
United States
Ruth
The price is CA $106
CA $120 total
includes taxes & fees
Nov 15 - Nov 16
Econo Lodge Clemson - University Area
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

20. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (901 reviews)
"Always a wonderful stay!"
United States
Laurrie
The price is CA $293
CA $325 total
includes taxes & fees
Oct 27 - Oct 28
The Shepherd Hotel Downtown Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in Downtown

A poolside area with outdoor seating and a view of a lake and forested hills.

Fairfield Inn & Suites Seneca Clemson Univ Area

3.0 star property
2 km from Downtown
View
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

Best Western Seneca-Clemson

2.5 star property
1.7 km from Downtown
View
A hotel dining area with a long table, multiple chairs, and a bar in the background.

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
2.2 km from Downtown
View
A restaurant interior with a counter, seating area, and a TV mounted on the wall.

Quality Inn Seneca US-123

2.5 star property
3.8 km from Downtown
View
An outdoor patio area with a fire pit, seating, and string lights.

Tru by Hilton Seneca Clemson

2.5 star property
8.4 km from Downtown
View
9.4
Exceptional
288 reviews
8.4
Very good
696 reviews
9.2
Wonderful
762 reviews
8.0
Very good
765 reviews
9.2
Wonderful
900 reviews
The price is CA $168
CA $185 total
includes taxes & fees
Nov 1 - Nov 2
The price is CA $131
CA $144 total
includes taxes & fees
Oct 28 - Oct 29
The price is CA $190
CA $209 total
includes taxes & fees
Nov 23 - Nov 24
The price is CA $118
CA $139 total
includes taxes & fees
Nov 1 - Nov 2
The price is CA $142
CA $157 total
includes taxes & fees
Nov 19 - Nov 20
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • No WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Learn more about Downtown
A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Keowee Reservoir.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Keowee Reservoir, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

8/10 Good
"Funeral in town. Only slept here. I think it is a good hotel for a two night personal stay."
Rebecca J 2-night trip
Posted 2 hours ago
Comfort Inn & Suites Clemson - University Area

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Oconee County Library Seneca Branch and Blue Ridge Arts Center as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
For your stay in Downtown, Historic Seneca Bungalow is one of the top choices based on our traveler data.
How many hotels can I expect to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 12 hotels and other accommodations in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
What can I see and do in this Seneca neighborhood?
Oconee County Library Seneca Branch, Blue Ridge Arts Center, and Seneca Historic District are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza, and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Applewood Shopping Center or Wyndham Plaza.