Title: Dona Ana Guest Houses from CA $224 | Expedia.ca [Hotels in Dona Ana](https://expedia.ca/Dona-Ana-Hotels.d3000350236.Travel-Guide-Hotels)[Vacation Rentals in Dona Ana](https://expedia.ca/Dona-Ana-Vacation-Rentals.d3000350236.Travel-Guide-VacationRentals)[Flights to Dona Ana](https://expedia.ca/Cheap-Flights-To-Dona-Ana.d3000350236.Travel-Guide-Flights)[Dona Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Dona-Ana.d3000350236.Car-Rental-Guide)[Dona Ana Vacation Packages](https://expedia.ca/Dona-Ana.d3000350236.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=3000350236&startDate=2026-03-13&endDate=2026-03-15&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=3000350236&startDate=2026-03-20&endDate=2026-03-22&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=3000350236&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=3000350236&startDate=2026-05-01&endDate=2026-05-03&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Dona Ana guest houses ![TV](https://images.trvl-media.com/lodging/120000000/119520000/119511600/119511573/803782bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119520000/119511600/119511573/6c4e0418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/120000000/119520000/119511600/119511573/ca482713.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/120000000/119520000/119511600/119511573/c7ac0f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 bed and pullout sofa kids and dogs welcome [](https://www.expedia.ca/Las-Cruces-Hotels-2-Bed-And-Pullout-Sofa-Kids-And-Dogs-Welcome.h119511573.Hotel-Information) Las Cruces 10/10 Exceptional (1 review) "We had a lovely time at this stay! It was very comfortable with an old charm. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sedona C. CA $119 CA $292 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Las-Cruces-Hotels-2-Bed-And-Pullout-Sofa-Kids-And-Dogs-Welcome.h119511573.Hotel-Information) ![Microwave, coffee/tea maker, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/120000000/119520000/119511500/119511494/ad258308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/120000000/119520000/119511500/119511494/5410d549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/120000000/119520000/119511500/119511494/371ae6cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/120000000/119520000/119511500/119511494/365b9d6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio Casita 5 mins to Farmer\`s mkt/dogs welcome! [](https://www.expedia.ca/Las-Cruces-Hotels-Studio-Casita-5-Mins-To-Farmers-Mktdogs-Welcome.h119511494.Hotel-Information) Las Cruces CA $82 CA $224 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Las-Cruces-Hotels-Studio-Casita-5-Mins-To-Farmers-Mktdogs-Welcome.h119511494.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/123000000/122290000/122285500/122285481/5ca716d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, travel crib, WiFi](https://images.trvl-media.com/lodging/123000000/122290000/122285500/122285481/f9a11eea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/123000000/122290000/122285500/122285481/e79021c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122290000/122285500/122285481/60a73cf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casita 3 mins to downtown farmers market [](https://www.expedia.ca/Las-Cruces-Hotels-Casita-3-Mins-To-Downtown-Farmers-Market.h122285481.Hotel-Information) Las Cruces 6.0/10 (2 reviews) "Adorable little “casita”! Very comfy & the hosts were so welcoming! The farm fresh eggs & English muffins were a great extra too! The coffee was amazing! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristin R. CA $98 CA $226 total includes taxes & fees Mar 21 - Mar 22 [](https://www.expedia.ca/Las-Cruces-Hotels-Casita-3-Mins-To-Downtown-Farmers-Market.h122285481.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511611/64e8bd55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511611/bcdfa8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511611/46a5edb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511611/b72c75d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 bed cute casita near NMSU, pet friendly [](https://www.expedia.ca/Las-Cruces-Hotels-1-Bed-Cute-Casita-Near-NMSU.h119511611.Hotel-Information) Las Cruces CA $120 CA $290 total includes taxes & fees Mar 4 - Mar 5 [](https://www.expedia.ca/Las-Cruces-Hotels-1-Bed-Cute-Casita-Near-NMSU.h119511611.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511648/fa435ac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511648/a3a753d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511648/16343b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511648/1a02686f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 king bd with big fenced back yard pets welcome [](https://www.expedia.ca/Las-Cruces-Hotels-1-King-Bd-With-Big-Fenced-Back-Yard-Pets-Welcome.h119511648.Hotel-Information) Las Cruces CA $120 CA $302 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Las-Cruces-Hotels-1-King-Bd-With-Big-Fenced-Back-Yard-Pets-Welcome.h119511648.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17®ionId=3000350236&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AA_SPRING_PROMO_3000350236) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDona-Ana-Guest-Houses.d3000350236-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDona-Ana-Guest-Houses.d3000350236-aaGuestHouses.Travel-Guide-Accommodation) ## Top Dona Ana Hotel Reviews ![Best Western Mission Inn](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/90d9a325_y.jpg) ### Best Western Mission Inn 10/10 Excellent "Friendly and helpful staff. Clean and comfortable room. " [](https://expedia.ca/Las-Cruces-Hotels-Best-Western-Mission-Inn.h20506.Hotel-Information) ![Drury Inn & Suites Las Cruces](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/0bffe062_y.jpg) ### Drury Inn & Suites Las Cruces 10/10 Excellent "Very clean spacious rooms, very nice staff. Great Breakfast options." [](https://expedia.ca/Las-Cruces-Hotels-Drury-Inn-Suites-Las-Cruces.h1723204.Hotel-Information) ![Comfort Suites University Las Cruces](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/3f986bbe_y.jpg) ### Comfort Suites University Las Cruces 10/10 Excellent "Pretty good breakfast " [](https://expedia.ca/Las-Cruces-Hotels-Comfort-Suites-University-Las-Cruces.h43179.Hotel-Information) ![Hotel Encanto de Las Cruces](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96_y.jpg) ### Hotel Encanto de Las Cruces 10/10 Excellent "Such a beautiful hotel! Great time here! would come bak. Staff was kind and " [](https://expedia.ca/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) ![Super 8 by Wyndham Las Cruces/White Sands Area](https://images.trvl-media.com/lodging/1000000/50000/42400/42327/5a1c8dad_y.jpg) ### Super 8 by Wyndham Las Cruces/White Sands Area 10/10 Excellent "." [](https://expedia.ca/Las-Cruces-Hotels-Super-8-By-Wyndham-Las-CrucesWhite-Sands-Area.h42327.Hotel-Information) ![Comfort Suites Las Cruces I-25 North](https://images.trvl-media.com/lodging/11000000/10330000/10320300/10320201/c5bb6ea5_y.jpg) ### Comfort Suites Las Cruces I-25 North 10/10 Excellent "Staff was very kind and room was clean" [](https://expedia.ca/Las-Cruces-Hotels-Comfort-Suites-Las-Cruces-I-25-North.h10320201.Hotel-Information) ![Comfort Inn & Suites Las Cruces Mesilla](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353805/518ac77c_y.jpg) ### Comfort Inn & Suites Las Cruces Mesilla 10/10 Excellent "It was very clean. The beds were comfortable. It was spacious and quiet. Great breakfast. Attendance was present to assist. Love the homemade waffles and appreciate eggs and sausage. Great coffee and orange juice! parking close to the door. It was all around just great!" [](https://expedia.ca/Las-Cruces-Hotels-Comfort-Inn-Suites-Las-Cruces-Mesilla.h1353805.Hotel-Information) ![Ramada Hotel & Conference Center by Wyndham Las Cruces](https://images.trvl-media.com/lodging/1000000/10000/3900/3871/b3828ca3_y.jpg) ### Ramada Hotel & Conference Center by Wyndham Las Cruces 10/10 Excellent "The front desk staff was attentive and friendly. The room was clean upon arrival and housekeeping did a great job at freshening it up for the next night. Overall great stay, Thank you" [](https://expedia.ca/Las-Cruces-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-Las-Cruces.h3871.Hotel-Information) ![Hampton Inn & Suites Las Cruces I-10](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/a6b6426a_y.jpg) ### Hampton Inn & Suites Las Cruces I-10 10/10 Excellent "I enjoyed the pool and the breakfast was good." [](https://expedia.ca/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-10.h12817768.Hotel-Information) ## Find out more about Dona Ana ## Dona Ana Guest Houses information | Number of reviews | 3 | | ----------------- | -------------- | | Accommodation | 8 Guest Houses | | Lowest Price | CA $224 | | Highest Price | CA $302 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [5 Star Hotels in Las Cruces ](https://www.expedia.ca/5Star-Las-Cruces-Hotels.s50-0-d2137.Travel-Guide-Filter-Hotels) - [Lodges in Anthony ](https://www.expedia.ca/Anthony-Lodges.d6140995-aaLodges.Travel-Guide-Accommodation) - [Inns in Chaparral ](https://www.expedia.ca/Chaparral-Inns.d3000350231-aaInns.Travel-Guide-Accommodation) - [Motels in Chaparral ](https://www.expedia.ca/Chaparral-Motels.d3000350231-aaMotels.Travel-Guide-Accommodation) - [Aparthotels in Fairacres ](https://www.expedia.ca/Fairacres-Apart-Hotels.d3000447742-aaApartHotels.Travel-Guide-Accommodation) - 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