Title: Top Hotels in Darlington County | Expedia.ca [Vacation Rentals in Darlington County](https://expedia.ca/Destinations-In-Darlington-County.d553248635976432334.Vacation-Rental-Destinations)[Darlington County Car Rentals](https://expedia.ca/Destinations-In-Darlington-County.d553248635976432334.Car-Rental-Destinations)[Darlington County Vacations](https://expedia.ca/Darlington-County.d553248635976432334.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/e2f9ecebd74ee7c8a618996f7964efa4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Jackie Rodriguez # Search Darlington County Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Darlington County Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Darlington+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976432334&latLong=34.299876%2C-79.876174&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Darlington+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976432334&latLong=34.299876%2C-79.876174&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Darlington+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976432334&latLong=34.299876%2C-79.876174&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&amenities=HOT_TUB) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Darlington+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976432334&latLong=34.299876%2C-79.876174&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&amenities=PETS) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Darlington+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976432334&latLong=34.299876%2C-79.876174&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&lodging=APARTMENT) ## Top Cities in Darlington County ![](https://mediaim.expedia.com/destination/2/e2f9ecebd74ee7c8a618996f7964efa4.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Hartsville [](https://expedia.ca/Hartsville-Hotels.d7762.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976432334&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976432334&startDate=2025-11-01&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976432334&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976432334&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels in Darlington County ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/51d8f371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0b9239a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC Florence 9.0/10 Wonderful (2175) "The front desk staff were extremely helpful, accommodating and welcoming. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Riley CA $133 CA $149 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/ebea43b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/b5687a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence Florence 8.6/10 Excellent (2413) "Property was clean convenient to I95 and reasonably priced" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $91 CA $102 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/c7afe694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/22e67acb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/83187168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area Florence 9.2/10 Wonderful (1133) "Friendly staff, clean, comfortable room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $144 CA $161 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/ad4579b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/bee831df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown Florence 8.8/10 Excellent (1003) "good stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaleecia CA $140 CA $157 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/a86309c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/67e23cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/719d7bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/w4000h2663x0y0-4c6e3b9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Florence Florence 7.8/10 Good (683) " Wry nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy CA $136 CA $152 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Florence-Hotels-Courtyard-By-Marriott-Florence.h84519.Hotel-Information) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/6676431c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/024086db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center Florence 7.8/10 Good (1247) "We had a nice stay. The staff we encountered were very friendly and helpful. We only stayed a short time but it was restful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Herbert CA $117 CA $131 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/01dca42d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/5b7b6acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/bccde616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 Florence 8.4/10 Very good (1000) "Very clean and friendly staff!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amber CA $131 CA $151 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/59604fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/22eb9cd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/16ca8b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 Florence 9.0/10 Wonderful (764) "Enjoyed our stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $148 CA $166 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/cbd95825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible, Non Smoking | Bathroom shower](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/7046523d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/2d26ec35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/73965d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Florence Florence 6.6/10 (1001) "Clean room, staff, parking, shops nearby" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allan CA $74 CA $83 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/38be55ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/f63ba12c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/c105915a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence Florence 8.0/10 Very good (1701) "Stayed one night. It was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gloria CA $139 CA $155 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/cfe51644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/7c55894f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/9afe242f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Marriott Florence Florence 8.8/10 Excellent (446) "Everything was very nice and the staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $139 CA $156 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/ca4e1745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, Multiple Beds](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/236a2b2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9 AM to 9 PM, pool umbrellas](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/520a38b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Florence Florence 9.0/10 Wonderful (673) "Staff was amazing. Property was quiet and nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori CA $144 CA $162 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/0724af0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/a0ec666e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/e765049f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/92c4b04d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Florence Florence 8.4/10 Very good (223) "The hotel was nice, staff were inviting and helpful. Room could’ve been a little cleaner but nothing too bad. I would definitely stay again!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) La'dymond CA $141 CA $158 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/86912dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/90789704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 Florence 9.0/10 Wonderful (525) "Always enjoy their breakfasts Clean rooms Comfy bed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacie CA $145 CA $162 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/5abcf1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/b2e2f539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/1aa3f791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/3bae1a69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Florence - Civic Center by IHG Florence 9.4/10 Exceptional (909) "Everything excellent from the staff to the food." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Russ CA $183 CA $205 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/ffb23f98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d2976b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/bac50e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center Florence 6.8/10 (1006) "Great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sedrin CA $89 CA $100 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/25ce2409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/ab68742b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/b510c653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/5cafd746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Florence, SC Florence 8.2/10 Very good (1011) "great check in lady Kendra so nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda CA $148 CA $166 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Florence-Hotels-Home2-Suites-By-Hilton-Florence.h7271220.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/83cb7582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/bdf580c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/37f52847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG Florence 8.6/10 Excellent (1017) "The staff was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARY C CA $160 CA $179 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/b1bbd639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/3ba2ede7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/65e0bac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence/I-95 North Florence 6.8/10 (1004) "Lady at the check in desk was friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William M CA $81 CA $91 total includes taxes & fees Nov 28 - Nov 29 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Non Smoking](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/00af3161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/43206f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 Florence 8.4/10 Very good (1006) "Good place to stay, good price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos CA $139 CA $161 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16®ionId=553248635976432334&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Darlington-County.d553248635976432334.Hotel-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Darlington-County.d553248635976432334.Hotel-Destinations) ## Top Darlington County Hotel Reviews ![Comfort Inn & Suites](//images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites 10/10 Excellent "The hotel was very clean and the staff is very friendly and helpful. Thank you for a comfortable nights sleep" [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](//images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "Yes. 100 % satisfaction. " [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Howard Johnson by Wyndham Florence](//images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "We're almost playing faculty was friendly" [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Tru by Hilton Florence I-95](//images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "Convenient to my event, quiet and clean. Stay with confidence." [](https://expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](//images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "Parking was fine.room was clean except the doors were were banged up staff was very nice Breakfast was good " [](https://expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![The Mantissa Hotel](//images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/39339da9_y.jpg) ### The Mantissa Hotel 10/10 Excellent "The location was conviene and the area was quite." [](https://expedia.ca/Florence-Hotels-The-Mantissa-Hotel.h15719033.Hotel-Information) ![Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG](//images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31_y.jpg) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG 10/10 Excellent "Internet was perfect, room clean. Staff excellent!" [](https://expedia.ca/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Park Inn by Radisson Florence, SC](//images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "The hotel and room were clean, the staff was extra friendly, and pakrking was accessible." [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Hampton Inn & Suites Hartsville](//images.trvl-media.com/lodging/11000000/10490000/10487500/10487496/1941549d_y.jpg) ### Hampton Inn & Suites Hartsville 10/10 Excellent "Clean rooms and all areas nice and clean." [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Hartsville.h10487496.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Darlington County - [Hartsville Hotels](https://expedia.ca/Hartsville-Hotels.d7762.Travel-Guide-Hotels) - [Darlington Hotels](https://expedia.ca/Darlington-Hotels.d7558.Travel-Guide-Hotels) - [Lamar Hotels](https://expedia.ca/Lamar-Hotels.d553248634998759979.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Darlington Raceway](https://expedia.ca/Darlington-Raceway-Hotels.0-l6144924-0.Travel-Guide-Filter-Hotels) - [Hotels near Neptune Island Waterpark](https://expedia.ca/Neptune-Island-Waterpark-Hotels.0-l643029888259751936-0.Travel-Guide-Filter-Hotels) - [Hotels near Coker College](https://expedia.ca/Coker-College-Hotels.0-l6144920-0.Travel-Guide-Filter-Hotels) - [Hotels near Palmetto Shores Lake](https://expedia.ca/Palmetto-Shores-Lake-Hotels.0-l553248635976195800-0.Travel-Guide-Filter-Hotels) - [Hotels near Kalmia Gardens](https://expedia.ca/Kalmia-Gardens-Hotels.0-l553248621532657338-0.Travel-Guide-Filter-Hotels) - [Hotels near Segars-McKinnon Heritage Preserve](https://expedia.ca/Segars-McKinnon-Heritage-Preserve-Hotels.0-l6144922-0.Travel-Guide-Filter-Hotels) - [Hotels near Hartsville Museum](https://expedia.ca/Hartsville-Museum-Hotels.0-l6144926-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Darlington County - [Vacation Homes in Darlington County](https://expedia.ca/Darlington-County-Private-Vacation-Homes.d553248635976432334-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Motels in Darlington County](https://expedia.ca/Darlington-County-Motels.d553248635976432334-aaMotels.Travel-Guide-Accommodation) - [Apartments in Darlington County](https://expedia.ca/Darlington-County-Apartments.d553248635976432334-aaApartments.Travel-Guide-Accommodation) - [Cottages in Darlington County](https://expedia.ca/Darlington-County-Cottages.d553248635976432334-aaCottages.Travel-Guide-Accommodation) - [Condo Rentals in Darlington County](https://expedia.ca/Darlington-County-Condos.d553248635976432334-aaCondos.Travel-Guide-Accommodation) - [Farmstay in Darlington County](https://expedia.ca/Darlington-County-Agritourism.d553248635976432334-aaAgritourism.Travel-Guide-Accommodation) - [Cabin Rentals in Darlington County](https://expedia.ca/Darlington-County-Cabins.d553248635976432334-aaCabins.Travel-Guide-Accommodation) - [Guest Houses in Darlington County](https://expedia.ca/Darlington-County-Guest-Houses.d553248635976432334-aaGuestHouses.Travel-Guide-Accommodation) - [B&B in Darlington County](https://expedia.ca/Darlington-County-Bed-And-Breakfast.d553248635976432334-aaBedAndBreakfast.Travel-Guide-Accommodation) ### Explore more hotels - [Fairfield Inn by Marriott Hartsville](https://expedia.ca/Florence-Hotels-Fairfield-Inn-By-Marriott-Hartsville.h202854.Hotel-Information) - [Hampton Inn & Suites Hartsville](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Hartsville.h10487496.Hotel-Information) - [Quality Inn](https://expedia.ca/Florence-Hotels-Quality-Inn.h5321.Hotel-Information) - [The Mantissa Hotel](https://expedia.ca/Florence-Hotels-The-Mantissa-Hotel.h15719033.Hotel-Information) - [The Landmark Inn](https://expedia.ca/Florence-Hotels-The-Landmark-Inn.h893817.Hotel-Information) - [Raceway Inn](https://expedia.ca/Florence-Hotels-Raceway-Inn.h1080506.Hotel-Information) - [Park Inn by Radisson Florence, SC](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) - [Howard Johnson by Wyndham Florence](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) - [Comfort Inn & Suites](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) - [La Quinta Inn & Suites by Wyndham Florence](https://expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) [See a list of all hotels in Darlington County](https://expedia.ca/All-Darlington-County-Hotels.d553248635976432334.Travel-Guide-City-All-Hotels) ### More ways to book - 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[Flights to Orange County](https://expedia.ca/Destinations-In-Orange-County.d603224.Flight-Destinations) - [Flights to San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Flight-Destinations) Cars - [Car rentals in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Car-Rental-Destinations) - [Car rental Myrtle Beach Airport (MYR)](https://expedia.ca/Car-Rentals-In-Myrtle-Beach-Intl.d5396813.Car-Rental-Guide) Cruises - [Cruises from San Diego County](https://expedia.ca/Cruises-from-San-Diego-County.d178304.Cruise-Departure-Port) Activities - [Things to do in Baldwin County](https://expedia.ca/Things-To-Do-In-Baldwin-County.d553248635976432245.Travel-Guide-Activities) - [Things to do in San Diego County](https://expedia.ca/Things-To-Do-In-San-Diego-County.d178304.Travel-Guide-Activities) - [Things to do in Orange County](https://expedia.ca/Things-To-Do-In-Orange-County.d603224.Travel-Guide-Activities) - [Things to do in Levy County](https://expedia.ca/Things-To-Do-In-Levy-County.d553248635976432502.Travel-Guide-Activities) Packages - [San Diego County Vacations](https://expedia.ca/San-Diego-County.d178304.Destination-Travel-Guides) - [Magnolia Plantation and Gardens](https://expedia.ca/Magnolia-Plantation-And-Gardens-Charleston.d6082613.Vacation-Attraction) - [Myrtle Beach State Park](https://expedia.ca/Myrtle-Beach-State-Park-Myrtle-Beach.d6079991.Vacation-Attraction) - [Ripley's Aquarium](https://expedia.ca/Ripleys-Aquarium-Myrtle-Beach.d6079963.Vacation-Attraction) - [Broadway at the Beach](https://expedia.ca/Broadway-At-The-Beach-Myrtle-Beach.d6079959.Vacation-Attraction) - [Family Kingdom Amusement Park](https://expedia.ca/Family-Kingdom-Amusement-Park-Myrtle-Beach.d6079999.Vacation-Attraction) General - [Visit Cherry Grove Beach](https://expedia.ca/North-Myrtle-Beach-Cherry-Grove-Beach.dx553248621561867974) - [Visit Orange County](https://expedia.ca/Orange-County.dx603224) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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