Title: Hotels by Independent in Charleston | Expedia.ca [Charleston Travel Guide](https://expedia.ca/Charleston.dx7182)[Hotels in Charleston](https://expedia.ca/Charleston-Hotels.d7182.Travel-Guide-Hotels)[Vacation Rentals in Charleston](https://expedia.ca/Charleston-Vacation-Rentals.d7182.Travel-Guide-VacationRentals)[Flights to Charleston](https://expedia.ca/Cheap-Flights-To-Charleston.d7182.Travel-Guide-Flights)[Charleston Car Rentals](https://expedia.ca/Car-Rentals-In-Charleston.d7182.Car-Rental-Guide)[Charleston Vacation Packages](https://expedia.ca/Charleston.d7182.Destination-Travel-Guides) ![Cypress Trees on the Horizon. A sting of cypress trees of various sizes extend across the horizon as the sunken sun paints the multicolored sky. ](https://images.trvl-media.com/place/7182/2c4b1a06-d3aa-4171-b8b6-0e4eaaa0e80e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7182/2c4b1a06-d3aa-4171-b8b6-0e4eaaa0e80e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 20 - Mar 21](https://www.expedia.ca/Hotel-Search?regionId=7182&startDate=2026-03-20&endDate=2026-03-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 21 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=7182&startDate=2026-03-21&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=7182&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=7182&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCharleston-Hotels-Independent.0-0-d7182--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCharleston-Hotels-Independent.0-0-d7182--bIndependent.Travel-Guide-Filter-Hotels) ## Top Charleston Hotel Reviews ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 8/10 Good "Beds were clean and well made however carpet in room was stained. There was a chicken nugget on the floor in the elevator upon arrival and was still there the next morning. Breakfast was good except for preparer wiping her nose with her plastic serving gloves on. Good coffee and easy check in." [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg) ### Candlewood Suites Cape Girardeau by IHG 6/10 Okay "Yes" [](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Amazing stay all around " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Business friendly, clean room staff very friendly, accommodating." [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Best Western Plus Sikeston I-55](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston I-55 10/10 Excellent "Room was clean, the bathroom had a good vent and nice lighting which we've had a problem with with other hotels. Very satisfied with our stay and breakfast was gold. " [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Pool not too cold and it was even snowing at one point. Staff was very friendly and helpful. Never had to wait for elevator. Breakfast waffles were excellent. Room was spacious. I’ve stayed in a lot of hotels, and this is one of the best. They get a 100/10 for amenities! " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Country Yard Inn and Suite](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a_y.jpg) ### Country Yard Inn and Suite 2/10 Terrible "The room was very dirty and The beds were not made with what looked like dried up blood on the sheets. There was used shampoo bottles in the shower the bathroom was very dirty. They smelt like mold " [](https://expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "We wished we could have stayed longer." [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 8/10 Good "Convenient stop on our longer trip" [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Apartments in Baker ](https://www.expedia.ca/Baker-Apartments.d553248634983252914-aaApartments.Travel-Guide-Accommodation) - [Apartments in Bell City ](https://www.expedia.ca/Bell-City-Apartments.d553248634983588961-aaApartments.Travel-Guide-Accommodation) - [Cheap Hotels in Benton ](https://www.expedia.ca/Benton-Hotels-Cheap-Hotels.0-0-d553248634983369680-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Benton ](https://www.expedia.ca/Benton-Hotels-Luxury-Hotel.0-0-d553248634983369680-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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