Title: Cairo Vacation Home Rentals from CA $222: Search Top Private Vacation Homes for Rent | Expedia.ca [Hotels in Cairo](https://expedia.ca/Cairo-Hotels.d6626.Travel-Guide-Hotels)[Vacation Rentals in Cairo](https://expedia.ca/Cairo-Vacation-Rentals.d6626.Travel-Guide-VacationRentals)[Flights to Cairo](https://expedia.ca/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights)[Cairo Car Rentals](https://expedia.ca/Car-Rentals-In-Cairo.d6626.Car-Rental-Guide)[Cairo Vacation Packages](https://expedia.ca/Cairo.d6626.Destination-Travel-Guides) ![Cairo Ohio River Bridge traversing over the Ohio River at sunset](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cairo Vacation Rentals - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-01-09&endDate=2026-01-11&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Cairo vacation homes ![Exterior detail](https://images.trvl-media.com/lodging/91000000/90930000/90923000/90922960/8049aee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90930000/90923000/90922960/de0a70e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90930000/90923000/90922960/df4ed428.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90930000/90923000/90922960/29a54441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Home just minutes from Interstate and Mall [](https://www.expedia.ca/Paducah-Hotels-Charming-Home.h90922960.Hotel-Information) Kevil 10/10 Exceptional (20) "We enjoyed staying here very much. Clean and close to where we wanted to be!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky C. CA $152 CA $258 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Paducah-Hotels-Charming-Home.h90922960.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106630000/106623200/106623184/8a1aff87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106630000/106623200/106623184/6520deeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106630000/106623200/106623184/a250fc1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/107000000/106630000/106623200/106623184/e22587fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom house near ball park in quiet neighborhood [](https://www.expedia.ca/Bardwell-Hotels-Charming-3-Bedroom-House-Near-Ball-Park-In-Quiet-Neighborhood.h106623184.Hotel-Information) Bardwell 10/10 Exceptional (12) "Quaint stay to see Grand and kids. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheila C. CA $124 CA $222 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Bardwell-Hotels-Charming-3-Bedroom-House-Near-Ball-Park-In-Quiet-Neighborhood.h106623184.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/c1fa9596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, internet, bed sheets](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/b75c6e64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/42584a6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/42ca857b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet Country Stay: Modern Home Near Paducah [](https://www.expedia.ca/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122882332.Hotel-Information) Cunningham CA $149 CA $394 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122882332.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-05&endDate=2026-01-06®ionId=6626&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCairo-Private-Vacation-Homes.d6626-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCairo-Private-Vacation-Homes.d6626-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Cairo Hotel Reviews ![Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286](https://images.trvl-media.com/lodging/54000000/53860000/53856300/53856204/f8ac9a8a_y.jpg) ### Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286 10/10 Excellent "We loved our stay in this country location. It was quiet and peaceful yet close enough to Paducah for shopping and restaurants. The home was spotless, and every amenity was available - basic kitchen supplies (mixer, oil, sugar, spices, and much more), lots of towels and blankets and pillows, wifi and TV, washer and dryer, and more I'm probably not thinking of.It was very cold and snowy during our visit, so we made the home a cozy place to watch movies and relax. We even had our three small dogs with us, and there was lots of yard space to walk them.If you visit here, don't miss the National Quilt Museum. It's not your grandmother's quilt - it's amazing fabric art! Oh, and we found a vegan restaurant we liked: Branch Out.Definitely recommend staying here!!!" [](https://expedia.ca/Quiet-Home-On-Horse-Farm.h53856204.Hotel-Information) ![Charming cottage overlooking Lake Acre](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/7bfe8087_y.jpg) ### Charming cottage overlooking Lake Acre 10/10 Excellent "Enjoyed our stay great hospitality, everything we needed was addressed. We would highly recommend staying there. Great location " [](https://expedia.ca/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information) ![Cozy cabins on beautiful Horseshoe Lake](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/53db6388_y.jpg) ### Cozy cabins on beautiful Horseshoe Lake 10/10 Excellent "The cabin was great" [](https://expedia.ca/Cozy-Cabins-On-Beautiful-Horseshoe-Lake.h90331191.Hotel-Information) ![Super 8 by Wyndham Charleston/Sikeston East MO](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg) ### Super 8 by Wyndham Charleston/Sikeston East MO 10/10 Excellent "Thank you " [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3_y.jpg) ### Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout. 10/10 Excellent "Very nice property. Loved the outdoor space and we would love to stay again! The owners are chef kiss. " [](https://expedia.ca/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information) ![The Rested Duck Mallard Room](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/29d5afe7_y.jpg) ### The Rested Duck Mallard Room 10/10 Excellent "It was fine. It was fairly clean and the bed was comfortable. No where to put anything down in the bathroom. " [](https://expedia.ca/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information) ![Peaceful secluded cabin located near Horseshoe Lake ](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/b6736ddb_y.jpg) ### Peaceful secluded cabin located near Horseshoe Lake 10/10 Excellent "The cabin is perfect for a quiet getaway. Location is great close to Dollar General, gas station and restaurants" [](https://expedia.ca/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information) ![Quality Inn Cairo I-57](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d_y.jpg) ### Quality Inn Cairo I-57 10/10 Excellent "Break fast was excellent " [](https://expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![La Center Motel](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/6218157c_y.jpg) ### La Center Motel 10/10 Excellent "The place was very clean" [](https://expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) ## Find out more about Cairo ## Cairo Vacation Homes information | Number of reviews | 31 | | ----------------- | ---------------- | | Accommodation | 5 Vacation Homes | | Lowest Price | CA $222 | | Highest Price | CA $394 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - 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