The best area to stay in Blytheville is along Interstate 55, particularly around the intersection with Highway 61, as it offers the most convenient access and a range of amenities.This area is primarily focused on convenience for travellers, with several hotels clustered together. You'll find a good selection of restaurants, from casual eateries to sit-down options, and a few retail outlets within easy reach. It's well-connected for those arriving by car, with clear signage and straightforward navigation.For business travellers, this area is particularly suitable. Its proximity to the interstate means quick access to corporate parks and industrial areas, and many hotels here cater to this audience with facilities like business centres and meeting rooms.Families will also find this area practical.