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A clock tower at Iowa State University surrounded by lush greenery.

Ames Vacation Rentals

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    Check prices for these dates

    Check prices for these dates, December 15–16, 2026

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    Our top choices for Ames vacation homes

    1. Campus & Downtown - Near Starbucks - Netflix - 2Br/1Ba

    A bed with two pillows and a framed landscape painting above it.

    2. Downtown & Campus Wifi with Netflix 2Br 1Ba

    A kitchen with white tiled walls, a coffee maker, and various glassware on shelves.

    3. 3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

    A modern kitchen with a double sink, white cabinets, and a view to a dining area.

    4. Cy's Retreat: Unique 3BR/2BA Prime Location. Steps from Jack Trice!

    A wooden attic room with a sloped ceiling, a door leading to another room, and shelves with framed items and memorabilia.

    5. Natural Nesting Grounds - Boone, IA

    A spacious living room with hardwood floors, a chandelier, a dining table with chairs, and a sofa.

    6. 2BR-1BA, Sleeps 5 | Prime Location

    Living area

    7. Sleeps 10 - 5BR - Minutes to Campus - Next to Park, Golf, Shopping

    A backyard with a wooden deck, a picnic table, and a small shed.

    8. 1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

    A wooden observation deck with a rope safety barrier and a wooden roof structure.

    9. Tranquil Home in Beautiful Setting

    A blue Adirondack chair with a small table beside it, placed on a blue and yellow star-patterned rug.

    10. A GREAT 4 Bedroom 2 Bath home with lots of room for fun It's The American Dream!

    A wooden deck with outdoor furniture, a sliding glass door, and a small window.

    11. Railroad themed 3-bedroom house in Boone The Main Street Station is pet friendly

    A room with a wooden door, a dining area with a table and chairs, a kitchen in the background, and a bed with a green blanket.

    12. Sleeps 6. Pets welcome. Wi-Fi. 3 bedroom house

    A room with two grey armchairs, a small table with a lamp, and a window with white curtains.

    13. Sleeps 6, 3BR-2.5BA | Easy I-35 Access

    A modern kitchen with a refrigerator, microwave, stove, and wooden cabinets.

    14. Cozy 2-bedroom house in peaceful Colo with AC

    A hallway with a wooden bench, a 'Guest Book,' and a 'Happy Home' sign.

    15. Spacious 5-bedroom house with AC and WiFi in fantastic NE Ankeny

    A modern kitchen with a central island, bar stools, stainless steel appliances, and a dining area in the background.

    16. Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

    A spacious living area with a modern kitchen, a dining area, and a large window providing natural light.

    17. Ankeny’s Best/Hot tub/Theatre Room/Game Room

    A hot tub with blue lighting, surrounded by four windows with light fixtures above.

    18. Enjoy a stylish experience at this centrally-located newly built home.

    A modern kitchen with a central island, a dining area, and a living room with a sofa and decorative pillows.

    19. New Spacious 4-bedroom house in charming Ankeny with WiFi, AC-Prime Location

    A modern apartment with a kitchen, living area, and a dining space.

    20. Spacious 4-bedroom house in Ankeny. For family, friends and business travelers.

    An outdoor patio with wicker furniture, a table, and a decorative lantern.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Ames and related destinations

    Home to Iowa State University, this friendly college town offers vibrant farmers markets and the stunning Reiman Gardens with its butterfly wing. Explore the historic downtown for local shops, catch a Cyclones game, or bike along the extensive trail network when the prairie wildflowers bloom.

    See all hotels in Ames

    A clock tower at Iowa State University surrounded by lush greenery.

    Top reviews in Ames

    Home2 Suites By Hilton Ames

    An outdoor seating area with a fire feature, wicker ottomans, and a sofa under a pergola with string lights.

    Hampton Inn & Suites Ames

    A Hampton Inn & Suites with a covered entrance, stone pillars, and a welcoming sign.

    SpringHill Suites by Marriott Ames

    An outdoor seating area with stone walls, a fire pit, and modern furniture.

    Holiday Inn Express Des Moines Ankeny by IHG

    A modern hotel lobby with a seating area, a reception desk, and a refrigerator.

    Fairfield Inn & Suites Des Moines Altoona

    A hotel with a reflection in a calm body of water, surrounded by open fields.

    TownePlace Suites by Marriott Ames

    An outdoor patio with wicker furniture, a stone fireplace, and a grill.

    Comfort Inn and Suites Ames near ISU Campus

    A lobby with blue armchairs, a wooden table, and a brick wall.

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