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A clock tower at Iowa State University surrounded by lush greenery.

Ames Vacation Rentals

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    Check prices for these dates, December 15–16, 2026

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    Our top choices for Ames vacation homes

    1. Campus & Downtown - Near Starbucks - Netflix - 2Br/1Ba

    A kitchen with white cabinets, a wooden dining table, a white stove, and a microwave.

    2. Downtown & Campus Wifi with Netflix 2Br 1Ba

    A living room with a sofa, coffee table, and dining table. There are framed pictures on the wall, a lamp, and a plant.

    3. 3BR Getaway, Sleeps 6 | 2-3 Miles to ISU

    A dining area with a wooden table, chairs, and a decorative mirror. There are white paneled walls and a ceiling light fixture.

    4. Cy's Retreat: Unique 3BR/2BA Prime Location. Steps from Jack Trice!

    A cozy attic bedroom with a sloped ceiling, a bed with white bedding, a red curtain, and a small window.

    5. Natural Nesting Grounds - Boone, IA

    A spacious living room with hardwood floors, a chandelier, a dining table with chairs, and a sofa.

    6. 2BR-1BA, Sleeps 5 | Prime Location

    A modern living room with a sofa, a coffee table, and a TV mounted on the wall. There is a wooden ladder leaning against the wall and a small table with a bowl of chocolates.

    7. Sleeps 10 - 5BR - Minutes to Campus - Next to Park, Golf, Shopping

    A backyard with a wooden deck, a picnic table, and a small shed.

    8. 1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

    A two-story house with a front porch, a garage, and a small shed.

    9. Tranquil Home in Beautiful Setting

    A modern kitchen with wooden cabinets, a stainless steel sink, a built-in microwave, a white refrigerator, and a coffee maker on the counter.

    10. A GREAT 4 Bedroom 2 Bath home with lots of room for fun It's The American Dream!

    A kitchen with white cabinets, a granite countertop, a wooden floor, and a built-in oven.

    11. Railroad themed 3-bedroom house in Boone The Main Street Station is pet friendly

    A kitchen with wooden cabinets, a stainless steel oven, and a dining table with chairs.

    12. Sleeps 6. Pets welcome. Wi-Fi. 3 bedroom house

    A modern kitchen with white cabinets, a wooden countertop, a microwave, a stove, and a refrigerator.

    13. Sleeps 6, 3BR-2.5BA | Easy I-35 Access

    A two-story residential building with a white garage door, a front porch with a flower planter, and a well-maintained garden with various plants.

    14. Cozy 2-bedroom house in peaceful Colo with AC

    A hallway with a wooden bench, a 'Guest Book,' and a 'Happy Home' sign.

    15. Spacious 5-bedroom house with AC and WiFi in fantastic NE Ankeny

    A modern kitchen with white cabinets, stainless steel appliances, and a central island with bar stools.

    16. Entire Home-Beautiful 4BR, 3.5BA Retreat in Ankeny, Iowa 2 King Beds, Fenced, AC

    A spacious living area with a modern kitchen, a dining area, and a large window providing natural light.

    17. Ankeny’s Best/Hot tub/Theatre Room/Game Room

    A hot tub with blue lighting, surrounded by four windows with light fixtures above.

    18. Enjoy a stylish experience at this centrally-located newly built home.

    A modern kitchen with a central island, a dining area, and a living room with a sofa and decorative pillows.

    19. New Spacious 4-bedroom house in charming Ankeny with WiFi, AC-Prime Location

    A modern apartment with a kitchen, living area, and a dining space.

    20. Spacious 4-bedroom house in Ankeny. For family, friends and business travelers.

    A modern kitchen with white cabinets, a black countertop, and stainless steel appliances.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Ames and related destinations

    Home to Iowa State University, this friendly college town offers vibrant farmers markets and the stunning Reiman Gardens with its butterfly wing. Explore the historic downtown for local shops, catch a Cyclones game, or bike along the extensive trail network when the prairie wildflowers bloom.

    See all hotels in Ames

    A clock tower at Iowa State University surrounded by lush greenery.

    Top reviews in Ames

    Home2 Suites By Hilton Ames

    An outdoor seating area with a fire feature, wicker ottomans, and a sofa under a pergola with string lights.

    Hampton Inn & Suites Ames

    A modern dining area with a long table, patterned chairs, and hanging pendant lights.

    SpringHill Suites by Marriott Ames

    A modern hotel with a stone facade, labeled "Springhill Suites by Marriott," featuring a covered entrance and multiple windows.

    Holiday Inn Express Des Moines Ankeny by IHG

    A swimming pool with four lounge chairs and a view of trees through large windows.

    Fairfield Inn & Suites Des Moines Altoona

    A hotel with a reflection in a calm body of water, surrounded by open fields.

    TownePlace Suites by Marriott Ames

    An outdoor patio with wicker furniture, a stone fireplace, and a grill.

    Comfort Inn and Suites Ames near ISU Campus

    A lobby with a fireplace, seating area, and a reception desk.

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