Title: 4 Stars Hotels in Murphysboro, Illinois from CA $265 - Find Cheap Murphysboro Hotels With 4 Stars | Expedia.ca [Murphysboro Travel Guide](https://expedia.ca/Murphysboro.dx55857)[Hotels in Murphysboro](https://expedia.ca/Murphysboro-Hotels.d55857.Travel-Guide-Hotels)[Vacation Rentals in Murphysboro](https://expedia.ca/Murphysboro-Vacation-Rentals.d55857.Travel-Guide-VacationRentals)[Flights to Murphysboro](https://expedia.ca/Cheap-Flights-To-Murphysboro.d55857.Travel-Guide-Flights)[Murphysboro Car Rentals](https://expedia.ca/Car-Rentals-In-Murphysboro.d55857.Car-Rental-Guide)[Murphysboro Vacation Packages](https://expedia.ca/Murphysboro.d55857.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208702-Southern-Illinois.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Murphysboro, Illinois from CA $265 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Murphysboro 4 Star Hotels Tonight [Oct 8 - Oct 9](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2025-10-08&endDate=2025-10-09&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 9 - Oct 10](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2025-10-09&endDate=2025-10-10&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Murphysboro 4 Star Hotels ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/1aec7f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub, body treatments, hot stone massages](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/a53e0f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/14a96052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/e7229757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walker's Bluff Casino Resort Carterville 9.4/10 Exceptional (374) "Very nice room, nice scenery not an interstate running thru it" CA $238 CA $265 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Carterville-Hotels-Walkers-Bluff-Casino-Resort.h97064786.Hotel-Information) ![Honeymoon Suite, 1 King Bed, Non Smoking, Courtyard View | View from room](https://images.trvl-media.com/lodging/34000000/33420000/33418200/33418130/3020a524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Suite, 1 King Bed, Non Smoking, Park View](https://images.trvl-media.com/lodging/34000000/33420000/33418200/33418130/5dbc606e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/34000000/33420000/33418200/33418130/7c0d17e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/34000000/33420000/33418200/33418130/7e984039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Davie School Inn Anna 10/10 Exceptional (51) "One of the coolest and unique places we’ve stayed. It’s clean, quiet and the decor is perfect for this converted school. It felt like a slumber party in a classroom! " [](https://www.expedia.ca/Anna-Hotels-Davie-School-Inn.h33418130.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Murphysboro-Hotels.s40-0-d55857.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Murphysboro-Hotels.s40-0-d55857.Travel-Guide-Filter-Hotels) ## Learn more about Murphysboro Barbecue enthusiasts flock to the Apple Festival and award-winning 17th Street BBQ for Southern Illinois' most celebrated smoked meats. Outdoor adventurers can explore nearby Kinkaid Lake's fishing spots or take a short drive to Shawnee National Forest's hiking trails. [See all hotels in Murphysboro](https://www.expedia.ca/Hotel-Search?startDate=2025-10-22&endDate=2025-10-23&adults=2®ionId=55857) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208702-Southern-Illinois.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by Southernmost Illinois Tourism Bureau ## Top Murphysboro Hotel Reviews ## Find out more about Murphysboro If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Murphysboro are calling your name. Known for providing first-rate service in amazing locations, each of the Murphysboro 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Murphysboro. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Murphysboro, Illinois, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Murphysboro hotels with 4 Stars provide everything you need to unwind in style. ## Frequently asked questions ### How much does it cost to stay in a 4-star hotel in Murphysboro? > With Expedia's handy filter tool, locking in an awesome deal on a 4-star hotel in Murphysboro just got simpler. Start by keying in your chosen arrival date and length of your break. Then list the results by price and pick a property that best fits your budget and style. > > > > - Search for the lowest price from CA $265 ### What's the difference between 5-star and 4-star hotels in Murphysboro? > Offering an inviting guest experience and upscale décor, 4-star hotels are an excellent option for your Murphysboro vacation. These kinds of accommodations generally feature loads of useful amenities that make it simple to unpack and recharge — think 24-hour room service, pools and restaurants. Or enjoy even more lavishness at a 5-star hotel designed to spoil you with high-end perks and amenities. Round-the-clock concierge service, premium toiletries and gourmet dining are typically included at these deluxe retreats. ### Does Murphysboro have any 4-star all-inclusive resorts? > Use our "All inclusive" filter to find your dream resort in Murphysboro where just about everything is taken care of, from your accommodations to your meals, entertainment and activities. 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