Photo by Carl Anderson

Find hotels in Southwest Illinois, IL from CA $80
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Our top choices for Southwest Illinois hotels

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,659 reviews)
The price is CA $153
CA $173 total
includes taxes & fees
Feb 26 - Feb 27

Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,003 reviews)
The price is CA $135
CA $162 total
includes taxes & fees
Mar 13 - Mar 14

Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
9.0 out of 10, Wonderful, (1,000 reviews)
The price is CA $141
CA $159 total
includes taxes & fees
Mar 8 - Mar 9

SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
8.8 out of 10, Excellent, (932 reviews)
The price is CA $105
CA $116 total
includes taxes & fees
Mar 1 - Mar 2

Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
9.0 out of 10, Wonderful, (1,004 reviews)
The price is CA $147
CA $166 total
includes taxes & fees
Mar 8 - Mar 9

Country Hearth Inn & Suites Edwardsville St. Louis
Country Hearth Inn & Suites Edwardsville St. LouisEdwardsville
8.6 out of 10, Excellent, (669 reviews)
The price is CA $125
CA $143 total
includes taxes & fees
Feb 22 - Feb 23

Best Western U. S. Inn
Best Western U. S. InnNashville
8.6 out of 10, Excellent, (402 reviews)
The price is CA $120
CA $131 total
includes taxes & fees
Feb 22 - Feb 23

The Principal Hotel
The Principal HotelColumbia
9.8 out of 10, Exceptional, (206 reviews)
The price is CA $147
CA $164 total
includes taxes & fees
Mar 1 - Mar 2

Laketree Inn And Suites Marion
Laketree Inn And Suites MarionMarion
8.0 out of 10, Very good, (180 reviews)
The price is CA $95
CA $106 total
includes taxes & fees
Mar 24 - Mar 25

Comfort Inn & Suites Greenville I-70
Comfort Inn & Suites Greenville I-70Greenville
8.4 out of 10, Very good, (428 reviews)
The price is CA $123
CA $137 total
includes taxes & fees
Mar 8 - Mar 9

Best Western Plus MidAmerica Hotel
Best Western Plus MidAmerica HotelMascoutah
9.0 out of 10, Wonderful, (1,001 reviews)
The price is CA $136
CA $155 total
includes taxes & fees
Feb 22 - Feb 23

Ramada by Wyndham Vandalia
Ramada by Wyndham VandaliaVandalia
7.8 out of 10, Good, (819 reviews)
The price is CA $93
CA $101 total
includes taxes & fees
Feb 23 - Feb 24

Holiday Inn Express & Suites Vandalia by IHG
Holiday Inn Express & Suites Vandalia by IHGVandalia
8.8 out of 10, Excellent, (791 reviews)
The price is CA $160
CA $174 total
includes taxes & fees
Mar 1 - Mar 2

Quality Inn & Suites Vandalia near I-70 and Hwy 51
Quality Inn & Suites Vandalia near I-70 and Hwy 51Vandalia
8.4 out of 10, Very good, (1,000 reviews)
The price is CA $85
CA $93 total
includes taxes & fees
Feb 26 - Feb 27

Holiday Inn Carbondale-Conference Center by IHG
Holiday Inn Carbondale-Conference Center by IHGCarbondale
8.8 out of 10, Excellent, (656 reviews)
The price is CA $141
CA $162 total
includes taxes & fees
Feb 25 - Feb 26

Americas Best Value Inn Vandalia
Americas Best Value Inn VandaliaVandalia
7.8 out of 10, Good, (196 reviews)
The price is CA $68
CA $74 total
includes taxes & fees
Mar 1 - Mar 2

Powhatan Motel
Powhatan MotelPocahontas
8.6 out of 10, Excellent, (196 reviews)
The price is CA $127
CA $135 total
includes taxes & fees
Mar 1 - Mar 2

Best Western Saluki Inn
Best Western Saluki InnCarbondale
8.0 out of 10, Very good, (1,001 reviews)
The price is CA $98
CA $116 total
includes taxes & fees
Feb 25 - Feb 26

Hampton Inn St. Louis - Columbia
Hampton Inn St. Louis - ColumbiaColumbia
8.6 out of 10, Excellent, (485 reviews)
The price is CA $150
CA $167 total
includes taxes & fees
Mar 8 - Mar 9

Baymont by Wyndham Marion
Baymont by Wyndham MarionMarion
8.4 out of 10, Very good, (1,073 reviews)
The price is CA $123
CA $148 total
includes taxes & fees
Mar 1 - Mar 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

Photo by Carl Anderson
Open Photo by Carl Anderson
Top Southwest Illinois Hotel Reviews
Recent Reviews in Southwest Illinois

Drury Plaza Hotel Mt. Vernon
10/10 Excellent
More cheap stays in Southwest Illinois

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is CA $70 per night from Mar 1 to Mar 2
CA $70
CA $80 total
Mar 1 - Mar 2
includes taxes & fees
7/10 Good! (1,005 reviews)
Hotels in Southwest Illinois with star rating

4 Star Hotels
4 properties
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