A marshy landscape with water, trees, and a distant city skyline.

Ladys Island Luxury Vacations

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Top Luxury vacation packages in Ladys Island

Price found within the past 48 hours. Click for updated prices.
  • Sept 30 - Oct 4

    Water's Edge Inn - Adults Only + Flight

    Folly Beach
    4 nights
    3.5 star property
    9.6/10 - Exceptional (487 reviews)
    Roundtrip Detroit (DTW) - Charleston (CHS)
    DTW - CHSNonstop CHS - DTW1 stop
    CA $1,515
    CA $1,171
    per traveller
    found 1 day ago
    Water's Edge Inn - Adults Only
  • Sept 30 - Oct 4

    Planters Inn + Flight

    Charleston Historic District
    4 nights
    4.5 star property
    9.6/10 - Exceptional (1,004 reviews)
    "My husband and I have stayed in two other Relais and Chateaux properties (Hotel Wailea in Maui and Chatham Inn in Cape Cod) and both were stunning in terms of hotel grounds, cleanliness, room and hotel decor and staff helpfulness and service. For each of our three stays we were celebrating special occasions and all locations personalized our birthday and anniversary occasions with champagne and a personal note. Planters Inn sent a piece of coconut cake for my 66th birthday which was delicious..."
    Reviewed August 4, 2026
    Roundtrip Detroit (DTW) - Charleston (CHS)
    DTW - CHSNonstop CHS - DTW1 stop
    CA $3,351
    CA $2,128
    per traveller
    found 1 day ago
    Planters Inn
  • Sept 30 - Oct 4

    The Ryder Hotel + Flight

    Charleston Historic District
    4 nights
    3.5 star property
    8.8/10 - Excellent (1,128 reviews)
    "The property personnel was great greeted us very well with the parking and front counter. Only problem we had was the cleaning crew never cleaned the bathrooms and the room I was in which was room 333 had a musty, moldy smell when you weren’t in there for a while the restaurant had pretty good food. The coffee bar they had upfront. It wasn’t the best in the world."
    Reviewed August 6, 2026
    Roundtrip Detroit (DTW) - Charleston (CHS)
    DTW - CHSNonstop CHS - DTW1 stop
    CA $2,431
    CA $1,584
    per traveller
    found 1 day ago
    The Ryder Hotel
  • Sept 30 - Oct 4

    The Beach Club at Charleston Harbor Resort and Marina + Flight

    Mount Pleasant
    4 nights
    4.5 star property
    9.2/10 - Wonderful (1,070 reviews)
    "Loved the view and the pool! Room was very nice! Would have liked more restaurant choices, the fish house was not that good! Staff at main desk during check in were not that welcoming!"
    Reviewed August 6, 2026
    Roundtrip Detroit (DTW) - Charleston (CHS)
    DTW - CHSNonstop CHS - DTW1 stop
    CA $2,155
    CA $1,627
    per traveller
    found 1 day ago
    The Beach Club at Charleston Harbor Resort and Marina
  • Sept 30 - Oct 4

    The Vendue + Flight

    Charleston Historic District
    4 nights
    4.0 star property
    9.4/10 - Exceptional (1,113 reviews)
    "Some lint came out of the overhead vent onto our bedspread right after we checked in. After letting them know they immediately sent housekeeping to change all the linens. This is the second time we have stayed at the Vendue. Very convenient to lots of places within walking distance, including the Market. Will come again."
    Reviewed August 6, 2026
    Roundtrip Detroit (DTW) - Charleston (CHS)
    DTW - CHSNonstop CHS - DTW1 stop
    CA $2,026
    CA $1,580
    per traveller
    found 1 day ago
    The Vendue

Discover the most popular places to visit in Ladys Island

Top Luxury Ladys Island Hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Plan the perfect luxury Ladys Island vacation with Expedia

What are some benefits when booking luxury Ladys Island vacations?

When you book a luxury Ladys Island vacation, you get to enjoy some of the best amenities and special features available. Luxury vacation options often feature spa facilities right in your accommodation, along with room service and an on-site restaurant. The quality of the bedding and even the water pressure tends to be better, so it's the perfect solution for travellers looking to put their feet up and relax.

How can I find all-inclusive luxury vacations in Ladys Island?

If you're looking for something luxurious in Ladys Island, all you have to do is take advantage of our search filters. You can implement a filter to only show 5-star accommodations as well as some amenities you may be interested in, like spa facilities and hot tubs. When you opt for an all-inclusive package, you can enjoy luxury alongside a potential discount for booking your accommodation and flight together.

Can I book a cheap luxury vacation?

While luxury vacations tend to be on the more costly end of the spectrum, ranging from CA $1,171, there are a few methods you can try to lower the price as much as possible. When booking a flight and accommodation together, you can enjoy savings of up to 22. After implementing filters for luxury features, you can also sort by price to list the cheapest luxury packages first.

Are there luxury spa vacations?

Yes, luxury spa vacations are available and quite popular in Ladys Island. When you book one of these experiences, it's easier than ever to relax, unwind and recharge in between excursions. Either way, you can easily find spa vacations by implementing the spa filter in your search.

What should I look for in a luxury family vacation in Ladys Island?

When booking something for the whole family, it's important to consider exactly what kind of experience your family will want.Luxury packages make it easy to keep everyone happy with creature comforts. Kids especially enjoy features like pools, a delicious breakfast and plenty of space. Suites tend to offer your family members a bit more privacy and comfort compared to simple rooms throughout Ladys Island.

Can I book last-minute luxury vacations?

Yes, last-minute bookings are often available in Ladys Island. All you have to do is enter your travel dates to see what's available. Sometimes, you'll even find additional discounts for booking last-minute, as accommodations are desperate to fill their last remaining spaces.

What can help me find the best luxury vacation deals in Ladys Island?

You can use a few strategies to find the best deals on luxury vacation packages. Consider travelling during the off-season to take advantage of the typically lower overall prices. Additionally, staying in the less popular parts of Ladys Island or travelling to more obscure destinations altogether can often lead to lower prices.

Can I book a luxury vacation that is fully refundable?

Yes, fully refundable reservations are sometimes available on luxury vacation packages in Ladys Island. You can implement a filter for it specifically or check out the policy section on any one of your search results. It should clearly state what's necessary to qualify for a fully refundable booking.

Why should I book my luxury vacation with Expedia?

When you book with Expedia, you can enjoy a one-stop shop for all your travel planning needs. We offer accommodations as well as flights, and you may even be able to enjoy discounts by booking them together. Of course, Expedia Rewards members will find even more discounts and earn points that can be put toward discounts on future bookings.