Title: Luxury Vacations in Eastern Panama 2026/2026 | Expedia.ca ![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Eastern Panama Luxury Vacations ## Book a Hotel + Flight or Car together to unlock savings Photo by Nico Barner - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Flight and Luxury hotel deals in Eastern Panama Price found within the past 48 hours. Click for updated prices. ![Hotel Casa Panamá](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/6488c648_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Casa Panamá Casco Viejo CA $1,016 per person Jan 24 - Jan 31 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 7.4/10 Good! (577 reviews) Location is absolutely amazing Reviewed on Dec 1, 2025 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo CA $1,507 per person Jan 28 - Feb 1 found 15 hours ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Great location. Lovely lobby. Wonderful and abundant breakfast. Only drawback for us was our room -- it was a family room on the top floor and window was low, hard to see outside. Also a little loud from room next door. Reviewed on Nov 30, 2025 ![The Westin Panama](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/2aa9e1b3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Westin Panama Costa del Este CA $1,570 per person Jan 24 - Jan 31 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 9/10 Wonderful! (304 reviews) Our stay at the Westin Panama was great, from the staff to the breakfast in the morning. Staff were very responsive to requests and very pleasant. The breakfast buffet offered many varied options. Reviewed on Nov 28, 2025 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco CA $1,286 per person Jan 24 - Jan 31 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Every thing was perfect. Great hotel..! recommended 100% Reviewed on Dec 1, 2025 ![Yoo by Wynwood House](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/f526e4da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Yoo by Wynwood House Calidonia CA $1,686 per person Feb 9 - Feb 15 found 8 hours ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 9.2/10 Wonderful! (5 reviews) Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone. Reviewed on Jul 26, 2025 Don't see what you're looking for? See all available trips from Columbus to Eastern Panama [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-01-04/2026-01-11/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Luxury holidays in Eastern Panama Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista CA $1,212 per person Jan 24 - Jan 31 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) Everything was excellent. Reviewed on Dec 3, 2025 ![Hotel La Compania Del Valle](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/bd071da6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel La Compania Del Valle CA $2,209 per person Jan 13 - Jan 20 found 1 day ago Roundtrip flight included Montreal (YUL) to Panama City (PTY) 9.8/10 Exceptional! (54 reviews) super nice place i will come back again! Reviewed on Nov 13, 2025 ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### W Panama Bella Vista CA $2,036 per person Jan 24 - Jan 31 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 9/10 Wonderful! (1,001 reviews) W Panamá was an absolute amazing stay! The staff were extremely friendly and accommodating! I had two rooms reserved and called ahead of time to inquire on having the rooms side by side, the communication throughout my entire stay was excellent. My party and I were celebrating two birthdays and everything we asked for to be available at check in as a surprise was beautiful executed. The breakfast was delicious and the variety was extensive. I have no complaints whatsoever and truly look forward to staying at W Panamá again. Thank you for a great stay! Reviewed on Nov 29, 2025 Don't see what you're looking for? See all available trips from Columbus to Eastern Panama [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-01-04/2026-01-11/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Luxury holidays in Eastern Panama Price found within the past 48 hours. Click for updated prices. ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo CA $1,204 per person Feb 27 - Mar 2 found 1 day ago Roundtrip non-stop flight included Toronto (YYZ) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Great location. Lovely lobby. Wonderful and abundant breakfast. Only drawback for us was our room -- it was a family room on the top floor and window was low, hard to see outside. Also a little loud from room next door. Reviewed on Nov 30, 2025 ![La Concordia Boutique Hotel](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/3645c5b6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### La Concordia Boutique Hotel Casco Viejo CA $1,421 per person Jan 9 - Jan 12 found 2 hours ago Roundtrip non-stop flight included Toronto (YYZ) to Panama City (PTY) 9.6/10 Exceptional! (191 reviews) Beautiful room Good location Reviewed on Nov 29, 2025 ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Dreams Playa Bonita Panama - All Inclusive CA $1,816 per person Jan 16 - Jan 19 found 24 hours ago Roundtrip non-stop flight included Toronto (YYZ) to Panama City (PTY) 7.4/10 Good! (1,002 reviews) This one of the best vacation I ever had. Reviewed on Dec 4, 2025 Don't see what you're looking for? See all available trips from Columbus to Eastern Panama [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-01-04/2026-01-11/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Luxury holidays in Eastern Panama Price found within the past 48 hours. Click for updated prices. ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites CA $1,037 per person Feb 12 - Feb 16 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 10/10 Exceptional! (1 review) ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo CA $1,561 per person Feb 12 - Feb 16 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Great location. Lovely lobby. Wonderful and abundant breakfast. Only drawback for us was our room -- it was a family room on the top floor and window was low, hard to see outside. Also a little loud from room next door. Reviewed on Nov 30, 2025 ![La Concordia Boutique Hotel](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/3645c5b6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### La Concordia Boutique Hotel Casco Viejo CA $1,924 per person Feb 14 - Feb 18 found 5 hours ago Roundtrip non-stop flight included Toronto (YTO) to Panama City (PTY) 9.6/10 Exceptional! (191 reviews) Beautiful room Good location Reviewed on Nov 29, 2025 Don't see what you're looking for? See all available trips from Columbus to Eastern Panama [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-01-04/2026-01-11/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Plan the perfect luxury Eastern Panama vacation with Expedia #### What are some benefits when booking luxury Eastern Panama vacations? When you book a luxury Eastern Panama vacation, you get to enjoy some of the best amenities and special features available. Luxury vacation options often feature spa facilities right in your accommodation, along with room service and an on-site restaurant. The quality of the bedding and even the water pressure tends to be better, so it's the perfect solution for travellers looking to put their feet up and relax. #### How can I find all-inclusive luxury vacations in Eastern Panama? If you're looking for something luxurious in Eastern Panama, all you have to do is take advantage of our search filters. You can implement a filter to only show 5-star accommodations as well as some amenities you may be interested in, like spa facilities and hot tubs. When you opt for an all-inclusive package, you can enjoy luxury alongside a potential discount for booking your accommodation and flight together. #### Can I book a cheap luxury vacation? While luxury vacations tend to be on the more costly end of the spectrum, ranging from CA $1,016, there are a few methods you can try to lower the price as much as possible. When booking a flight and accommodation together, you can enjoy savings of up to 31\. After implementing filters for luxury features, you can also sort by price to list the cheapest luxury packages first. #### Are there luxury spa vacations? Yes, luxury spa vacations are available and quite popular in Eastern Panama. When you book one of these experiences, it's easier than ever to relax, unwind and recharge in between excursions. Either way, you can easily find spa vacations by implementing the spa filter in your search. #### What should I look for in a luxury family vacation in Eastern Panama? When booking something for the whole family, it's important to consider exactly what kind of experience your family will want.Luxury packages make it easy to keep everyone happy with creature comforts. Kids especially enjoy features like pools, a delicious breakfast and plenty of space. Suites tend to offer your family members a bit more privacy and comfort compared to simple rooms throughout Eastern Panama. #### Can I book last-minute luxury vacations? Yes, last-minute bookings are often available in Eastern Panama. All you have to do is enter your travel dates to see what's available. Sometimes, you'll even find additional discounts for booking last-minute, as accommodations are desperate to fill their last remaining spaces. #### What can help me find the best luxury vacation deals in Eastern Panama? You can use a few strategies to find the best deals on luxury vacation packages. Consider travelling during the off-season to take advantage of the typically lower overall prices. Additionally, staying in the less popular parts of Eastern Panama or travelling to more obscure destinations altogether can often lead to lower prices. #### Can I book a luxury vacation that is fully refundable? Yes, fully refundable reservations are sometimes available on luxury vacation packages in Eastern Panama. You can implement a filter for it specifically or check out the policy section on any one of your search results. It should clearly state what's necessary to qualify for a fully refundable booking. #### Why should I book my luxury vacation with Expedia? When you book with Expedia, you can enjoy a one-stop shop for all your travel planning needs. We offer accommodations as well as flights, and you may even be able to enjoy discounts by booking them together. Of course, Expedia Rewards members will find even more discounts and earn points that can be put toward discounts on future bookings. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ### Top Luxury Vacation Destinations > - [Luxury vacations in India ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/80/India) > - [Luxury vacations in France ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/59/France) > - [Luxury vacations in Switzerland ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/174/Switzerland) > - [Luxury vacations in Canada ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/31/Canada) > - [Luxury vacations in Jamaica ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/88/Jamaica) > - [Luxury vacations in Italy ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/86/Italy) > - [Luxury vacations in New Zealand ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/133/New-Zealand) > - [Luxury vacations in the Maldives ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/109/Maldives) > - [Luxury vacations in Costa Rica ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/42/Costa-Rica) > - [Luxury vacations in Florida Keys ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/6023765/Florida-Keys) > - [Luxury vacations in Mexico ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/117/Mexico) > - [Luxury vacations in the Caribbean ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/6022969/Caribbean) > - [Luxury vacations in Zanzibar ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/4186/Zanzibar) > - [Luxury vacations in Cancun ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/179995/Cancun) > - [Luxury vacations in Kerala ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/602187/Kerala) > - [Luxury vacations in Australia ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/10/Australia) > - [Luxury vacations in Puglia ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/6048562/Puglia) > - [Luxury vacations in Cuba ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/44/Cuba) > - [Luxury vacations in Cyprus ](https://www.expedia.ca/lp/theme-vacations/luxury-vacations/45/Cyprus) ## More Vacations Ideas [Flights to Eastern Panama ](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[ Eastern Panama Hotels ](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[ Eastern Panama Vacation Rentals ](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[ Eastern Panama Car Rentals ](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[ Eastern Panama Vacations ](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides)[ Things to do in Eastern Panama ](https://expedia.ca/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app