A tropical island with palm trees and a clear blue sky.
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Panama Honeymoon Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Honeymoon vacation packages in Panama

Price found within the past 48 hours. Click for updated prices.
  • Jan 8 - Jan 12

    Riande Aeropuerto Hotel & Casino + Flight

    Tocumen Airport
    4 nights
    4.0 star property
    8.6/10 - Excellent (1,813 reviews)
    Roundtrip • Toronto (YTO) - Panama City (PTY)
    YYZ - PTY • 1 stop PTY - YYZ • 2 stops
    CA $1,770
    CA $1,272
    per traveller
    found 1 day ago
    Riande Aeropuerto Hotel & Casino
  • Dec 19 - Dec 23

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    4 nights
    4.0 star property
    9.2/10 - Wonderful (1,001 reviews)
    Roundtrip • Toronto (YTO) - Panama City (PTY)
    YYZ - PTY • 1 stop PTY - YYZ • 1 stop
    CA $3,464
    CA $1,929
    per traveller
    found 1 day ago
    Central Hotel Panama Casco Viejo
  • Dec 28 - Jan 3

    Megapolis Hotel Panamá + Flight

    San Francisco
    6 nights
    4.5 star property
    8.6/10 - Excellent (1,839 reviews)
    Roundtrip • Toronto (YTO) - Panama City (PTY)
    YYZ - PTY • 1 stop PTY - YYZ • 2 stops
    CA $4,521
    CA $2,653
    per traveller
    found 1 day ago
    Megapolis Hotel Panamá
  • Jan 25 - Jan 31

    Villa Botero By Casa Mojito B&B + Flight

    Rio Hato
    6 nights
    3.0 star property
    9.8/10 - Exceptional (69 reviews)
    "Christophe and his family were amazing hosts. The breakfast was incredible and fit for a king. The grounds, room and pool were decorated beautifully and very well maintained. We would stay here again in a heartbeat. We highly recommend this place."
    Reviewed June 17, 2026
    Roundtrip • Toronto (YYZ) - Rio Hato (RIH)
    YYZ - RIH • Nonstop RIH - YYZ • 1 stop
    CA $2,017
    CA $1,483
    per traveller
    found 12 hours ago
    Villa Botero By Casa Mojito B&B
  • Jan 8 - Jan 12

    Sofitel Legend Casco Viejo, Panama City + Flight

    Casco Viejo
    4 nights
    5.0 star property
    9.8/10 - Exceptional (771 reviews)
    "Magnificent property. Location. Staff. Quality of all, staff, facilities, best place in Panama!"
    Reviewed October 30, 2026
    Roundtrip • Toronto (YTO) - Panama City (PTY)
    YYZ - PTY • 1 stop PTY - YYZ • 2 stops
    CA $3,046
    CA $2,297
    per traveller
    found 1 day ago
    Sofitel Legend Casco Viejo, Panama City

Discover the most popular places to visit in Panama

What to do in Panama

Top Honeymoon Panama Hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a Panama vacation package cost?

Custom build your Panama vacation package from a low CA $1,272. Choose from any combination of rental cars, flights and hotels to pull together the trip you've been dreaming about. Remember to add on some activities and experiences!

How do I get a cheap travel package to Panama?

One of the easiest ways to save cash (and time) is to combine your bookings with Expedia. Hotels, flights, rental cars and activities — we've got them all. Select the combination that suits you and watch your savings stack up. Of course, a package deal is never one-size-fits-all. That's why we offer over 550 airlines and 1,000,000 hotels worldwide, which lets you customize your Panama vacation.

Where should I stay in Panama?

Panama City is a great place to visit. It draws in many visitors who come to check out its biggest sights, such as Bridge of the Americas and Miraflores Locks.

What are the top hotels in Panama?

When it comes to hotels in Panama City, Hotel Riu Plaza Panama and Crowne Plaza Panama Airport, an IHG Hotel are two terrific options. If you're also visiting Bocas del Toro, Playa Tortuga Hotel Beach And Resort and Azul Paradise will make you feel at home.

How far in advance should I book my Panama vacation?

It's difficult to pick the ideal time for airfares, but we usually say the earlier, the better. Most international journeys on Expedia become available up to 12 months in advance. If you're booking last minute, fear not. Discounted prices appear from time to time just weeks before departure dates.

What does an Expedia Panama travel package include?

Hotels, rental cars and flights, or any combination of them — it's up to you! Whether you're venturing to Panama with the kids or traveling solo, there's a package to fit your budget and style. Once you've made your booking, why not add on one or two tours or activities?

What should I know before booking a Panama travel package?

A travel package can be customized for your budget and is a terrific way to make your hard-earned dollars stretch further. How much you include is up to you. Rental cars, hotels and flights — come up with a combination that suits your plans.

Can I choose my airline with a Panama Expedia vacation package?

Yes — and it's simple too. Expedia has access to more than 550 partner airlines all over the world. Our packages give you the flexibility to pick from available flights, hotels and activities that fit your needs.

If I'm not able to travel, can I cancel my Panama vacation package?

Because we know life is full of surprises, the answer is yes. For further information, head to our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to change or cancel it for free. Your airline, hotel or car rental company may impose a fee if you made your booking a while ago.