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CA $522 Cheap Flights from Buffalo (BUF) to La Crosse (LSE)

View CA $522 flight on Tue, Sep 29, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to La Crosse, WI (LSE-La Crosse Municipal)

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Cheap flights from Buffalo (BUF) to La Crosse (LSE)

Prices were available within the past 7 days and start at CA $522 for one-way flights and CA $393 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
LSE
La Crosse
CA $393 Roundtrip, found 11 hours ago
CA $393
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Tue, Sep 29 from Buffalo to La Crosse, returning Tue, Oct 6, priced at CA $393 found 11 hours ago
American Airlines
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
LSE
La Crosse
CA $400 Roundtrip, found 11 hours ago
CA $400
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Tue, Sep 29 from Buffalo to La Crosse, returning Tue, Oct 6, priced at CA $400 found 11 hours ago
American Airlines
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
LSE
La Crosse
CA $504 Roundtrip, found 11 hours ago
CA $504
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Tue, Sep 29 from Buffalo to La Crosse, returning Tue, Oct 6, priced at CA $504 found 11 hours ago
American Airlines
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
LSE
La Crosse
CA $512 Roundtrip, found 11 hours ago
CA $512
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Tue, Sep 29 from Buffalo to La Crosse, returning Tue, Oct 6, priced at CA $512 found 11 hours ago
American Airlines
Sat, Sep 26 - Sat, Oct 3
BUF
Buffalo
LSE
La Crosse
CA $555 Roundtrip, found 11 hours ago
CA $555
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Sep 26 from Buffalo to La Crosse, returning Sat, Oct 3, priced at CA $555 found 11 hours ago
American Airlines
Tue, Sep 29 - Sat, Oct 10
BUF
Buffalo
LSE
La Crosse
CA $562 Roundtrip, found 11 hours ago
CA $562
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Tue, Sep 29 from Buffalo to La Crosse, returning Sat, Oct 10, priced at CA $562 found 11 hours ago
American Airlines
Sat, Sep 26 - Mon, Oct 5
BUF
Buffalo
LSE
La Crosse
CA $610 Roundtrip, found 11 hours ago
CA $610
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Sep 26 from Buffalo to La Crosse, returning Mon, Oct 5, priced at CA $610 found 11 hours ago
American Airlines
Fri, Oct 2 - Wed, Oct 7
BUF
Buffalo
LSE
La Crosse
CA $617 Roundtrip, found 11 hours ago
CA $617
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Fri, Oct 2 from Buffalo to La Crosse, returning Wed, Oct 7, priced at CA $617 found 11 hours ago
American Airlines
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
LSE
La Crosse
CA $619 Roundtrip, found 11 hours ago
CA $619
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Tue, Sep 29 from Buffalo to La Crosse, returning Tue, Oct 6, priced at CA $619 found 11 hours ago
American Airlines
Mon, Sep 28 - Wed, Oct 7
BUF
Buffalo
LSE
La Crosse
CA $624 Roundtrip, found 11 hours ago
CA $624
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Mon, Sep 28 from Buffalo to La Crosse, returning Wed, Oct 7, priced at CA $624 found 11 hours ago
American Airlines
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
LSE
La Crosse
CA $627 Roundtrip, found 11 hours ago
CA $627
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Tue, Sep 29 from Buffalo to La Crosse, returning Tue, Oct 6, priced at CA $627 found 11 hours ago

Frequently asked questions

How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal) cost?
You can find cheap one-way flights from CA $522 and cheap return flights from CA $393 BUF to LSE with Expedia. Return flights often range between CA$934 and CA$1594. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when BUF to LSE ticket fares go up or down.
What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
The cheapest months to fly from BUF to LSE are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
Enter BUF to LSE and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
American Airlines is one of the cheapest airlines offering connecting return flights from Buffalo Niagara Intl. (BUF) to La Crosse Municipal (LSE), with tickets starting from around CA$656 for flights that can be booked for departure within the next year. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
There are approximately 13 connecting flights per day from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal). Some common connection points include O'Hare Intl. (ORD), LaGuardia (LGA), and Detroit Metropolitan Wayne County (DTW).
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
The earliest flight from Buffalo Niagara International Airport (BUF) to La Crosse Municipal (LSE) typically departs around 6:00 AM local time. This flight is operated by American Airlines. This is a seasonal service active in December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
You'll typically find the most flights from Buffalo Niagara Intl. (BUF) to La Crosse Municipal (LSE) on a Tuesday, with around 3 flights available. This gives you a good selection for your travel plans. American Airlines is a major airline on this route. Flight schedules are quite consistent throughout the week, with only slight variations between days.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
The most popular departure times for flights from Buffalo Niagara Intl. (BUF) to La Crosse Municipal (LSE) are in the early morning, from 6am to 9am. American Airlines offers flights during this window. Many travelers prefer this because it allows for an early start to their travel day, getting you to your destination with plenty of time left.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
There are no nonstop flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal). For this route, which covers a distance of about 1017 kilometres, flights with one stop typically take around 4 hours 30 minutes. Flights with two or more stops usually take longer, averaging about 13 hours 18 minutes. Keep in mind that actual flight times can vary due to factors like layover duration, routing, and weather conditions.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
You can fly business class or first class between BUF and LSE. First class cabins are available on American Airlines.
How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for La Crosse, WI (LSE) from Buffalo, NY (BUF)?
If you're planning to travel to La Crosse from Buffalo Niagara Intl. (BUF), you can fly directly into La Crosse Municipal (LSE). Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to La Crosse, WI (LSE-La Crosse Municipal) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
La Crosse Municipal
Roundtrip price
CA $392
Distance
1010 km

Book with confidence

Buffalo to La Crosse Flights

The easy way to book your flights from Buffalo to La Crosse 

With Expedia, it’s simple to find and book flights to La Crosse from Buffalo whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to La Crosse Municipal, too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Buffalo to La Crosse today, tomorrow, or this week.  

 

Save dollars with cheap flights from Buffalo Niagara Intl., BUF to La Crosse Municipal, LSE 

Sort your search results by price to find great deals on your flight from Buffalo to La Crosse—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to La Crosse from Buffalo currently is just CA $393 rising to CA $889.  

Here are more money-saving tips: 

  • Fly in September when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to La Crosse  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to La Crosse from Buffalo 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to La Crosse with Expedia today.

Buffalo to La Crosse Flights

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