Title: CA $351 Cheap Flights from São Tomé - Expedia.ca ![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) # CA $351 Cheap Flights from São Tomé [View CA $351 flight on Fri, Jun 26, 2026](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:TMS,to:LIS,departure:26/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:351.00&airProductToken=AQpWCikIxKgBEgM1MTEYk5MBIK1IKPbekAMw_d-QAzhYQABYAXIHWDNBU1RCQQopCMSoARIDNjUyGK1IIIuSASjQ6ZADMJftkAM4WEABWAFyB1gzQVNUQkESCggBEAEYASoCRFQYASIECAEQASgCKAMoBDAB) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Hotels in São Tomé](https://expedia.ca/Sao-Tome-Hotels.d553248635975177343.Travel-Guide-Hotels)[São Tomé Car Rentals](https://expedia.ca/Car-Rentals-In-Sao-Tome.d553248635975177343.Car-Rental-Guide)[São Tomé Vacation Packages](https://expedia.ca/Sao-Tome.d553248635975177343.Destination-Travel-Guides) ## Popular airlines from São Tomé - ![TAP Portugal](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TP.svg) TAP Portugal - ![Hahn Air Systems](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_H1.svg) Hahn Air Systems - ![APG Distribution System](https://forever.travel-assets.com/flex/flexmanager/images/2025/03/25/landing_airline_sq_logo_A1.svg) APG Distribution System - ![Ethiopian Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_ET.svg) Ethiopian Airlines - ![TAAG Angola Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DT.svg) TAAG Angola Airlines - ![ASKY](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KP.svg) ASKY ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.ca/login) ## Cheapest flights from São Tomé These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Fri, May 8 - Fri, May 15 TMS São Tomé Island LIS Lisbon CA $793 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:08/05/2026TANYT&leg2=from:LIS,to:TMS,departure:15/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:792.30&airProductToken=AQo3CjUI1KABEgQxNTI4GJOTASCLkgEo3LqMAzDkvowDOFRAAFgBagdESVNDSU5UcghUTDBEU0k4MAo3CjUI1KABEgQxNTI3GIuSASCTkwEot4SNAzDEiI0DOFRAAFgBagdESVNDSU5UcghUTDBEU0k4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Fri, May 8 - Fri, May 15 TMS São Tomé Island LIS Lisbon CA $893 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:08/05/2026TANYT&leg2=from:LIS,to:TMS,departure:15/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:892.20&airProductToken=AQo2CjQI1KABEgQxNTI4GJOTASCLkgEo3LqMAzDkvowDOFRAAFgBagZCQVNJTlRyCFRMMEJTSTgwCjYKNAjUoAESBDE1MjcYi5IBIJOTASi3hI0DMMSIjQM4VEAAWAFqBkJBU0lOVHIIVEwwQlNJODASCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAAG Angola Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DT.gif) Fri, May 8 - Fri, May 15 TMS São Tomé Island LIS Lisbon CA $955 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:08/05/2026TANYT&leg2=from:LIS,to:TMS,departure:15/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:955.00&airProductToken=AQpWCikIxKgBEgM1MTEYk5MBIK1IKNa3jAMw3biMAzhYQABYAXIHWDNBU1RCQQopCMSoARIDNjUyGK1IIIuSASiwwowDMPfFjAM4WEABWAFyB1gzQVNUQkESCggBEAEYASoCRFQYASIECAEQASgCKAMoBDAB) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, Jan 31 - Sat, Feb 28 TMS São Tomé Island LIS Lisbon CA $963 Roundtrip found 3 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:31/01/2026TANYT&leg2=from:LIS,to:TMS,departure:28/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:962.20&airProductToken=AQo3CjUI1KABEgQxNTMyGJOTASCLkgEo4fiDAzDx-4MDOExAAFgBagdESVNDSU5UcghMTDBEU0k3MAo3CjUI1KABEgQxNTMxGIuSASCTkwEoqq6GAzC6sYYDOFRAAFgBagdESVNDSU5UcghUTDBEU0k4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAAG Angola Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DT.gif) Fri, May 8 - Fri, May 15 TMS São Tomé Island LIS Lisbon CA $1,016 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:08/05/2026TANYT&leg2=from:LIS,to:TMS,departure:15/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1015.20&airProductToken=AQpWCikIxKgBEgM1MTEYk5MBIK1IKNa3jAMw3biMAzhYQABYAXIHWDNBU1RCQQopCMSoARIDNjUyGK1IIIuSASiwwowDMPfFjAM4WEABWAFyB1gzQVNUQkESCggBEAEYASoCRFQYASIECAEQASgCKAMoBDAB) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Fri, May 8 - Fri, May 15 TMS São Tomé Island LIS Lisbon CA $1,020 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:08/05/2026TANYT&leg2=from:LIS,to:TMS,departure:15/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1019.70&airProductToken=AQo2CjQI1KABEgQxNTI4GJOTASCLkgEo3LqMAzDkvowDOFRAAFgBagZDTEFJTlRyCFRMMENMSTgwCjYKNAjUoAESBDE1MjcYi5IBIJOTASi3hI0DMMSIjQM4VEAAWAFqBkNMQUlOVHIIVEwwQ0xJODASCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, Jan 31 - Sat, Feb 28 TMS São Tomé Island LIS Lisbon CA $1,062 Roundtrip found 3 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:31/01/2026TANYT&leg2=from:LIS,to:TMS,departure:28/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1061.10&airProductToken=AQo2CjQI1KABEgQxNTMyGJOTASCLkgEo4fiDAzDx-4MDOExAAFgBagZCQVNJTlRyCExMMEJTSTcwCjYKNAjUoAESBDE1MzEYi5IBIJOTASiqroYDMLqxhgM4VEAAWAFqBkJBU0lOVHIIVEwwQlNJODASCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAAG Angola Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DT.gif) Fri, May 8 - Fri, May 15 TMS São Tomé Island LIS Lisbon CA $1,096 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:08/05/2026TANYT&leg2=from:LIS,to:TMS,departure:15/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1095.80&airProductToken=AQpWCikIxKgBEgM1MTEYk5MBIK1IKNa3jAMw3biMAzhYQABYAXIHWDNBU1RCQQopCMSoARIDNjUyGK1IIIuSASiwwowDMPfFjAM4WEABWAFyB1gzQVNUQkESCggBEAEYASoCRFQYASIECAEQASgCKAMoBDAB) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Fri, May 8 - Fri, May 15 TMS São Tomé Island LIS Lisbon CA $1,148 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:08/05/2026TANYT&leg2=from:LIS,to:TMS,departure:15/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1147.20&airProductToken=AQo3CjUI1KABEgQxNTI4GJOTASCLkgEo3LqMAzDkvowDOFRAAFgBagdQTFVTSU5UcghUTDBQVUk4MAo3CjUI1KABEgQxNTI3GIuSASCTkwEot4SNAzDEiI0DOFRAAFgBagdQTFVTSU5UcghUTDBQVUk4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, Oct 11 - Sat, Oct 18 TMS São Tomé Island LIS Lisbon CA $1,162 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:TMS,to:LIS,departure:11/10/2025TANYT&leg2=from:LIS,to:TMS,departure:18/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1161.50&airProductToken=AQo3CjUI1KABEgQxNTMyGJOTASCLkgEor4z6AjDEj_oCOEFAAFgBagdESVNDSU5UcghBTDBEU0kwMAo3CjUI1KABEgQxNTMxGIuSASCTkwEogNb6AjCQ2foCOEVAAFgBagdESVNDSU5UcghFTDBEU0k4MBIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ## Flights from São Tomé: Essential Travel Information | Cheapest flight from São Tomé | CA $793 (roundtrip) | | --- | --- | | Best airlines to fly from São Tomé | TAAG Angola Airlines, TAP Portugal, ASKY, Ethiopian Airlines | | Cheapest month to fly from São Tomé | May | | São Tomé IATA code | TMS | | São Tomé Country/State | Água Grande | | Airline ticket deals from São Tomé | CA $793 - CA $1,239 | ## How to find cheap flights from São Tomé #### How much is a flight from São Tomé? Flights from São Tomé are available at a range of prices. Attractive deals include one-way fares from CA $351 and roundtrip fares from CA $793. You'll often find the best deals in May. With Expedia, explore offers from multiple airlines and plan your journey effortlessly, ensuring you secure the perfect flight at a competitive price. #### How can I find cheap flights from São Tomé? Discovering affordable flights from São Tomé has never been easier, thanks to Expedia. We present a simple solution for comparing fares to a multitude of destinations, with one-way deals from CA $351 and roundtrip offers from CA $793. After choosing an enticing deal, enhance your search with our filters and sort by 'Price (Lowest)' to find the most economical and suitable options. Begin your journey with us today and relish the simplicity of securing cost-effective flights. #### How can I get the best deal on flights from São Tomé? For the best deal on flights from São Tomé, flexibility is key. Utilize our 'Show flexible dates' feature on Expedia to compare prices for different dates, and you may find deals when such offers are present. Remember, direct flights from São Tomé could come with a higher price tag, and different airlines' baggage policies might affect the total cost. Stay tuned with our latest offers to make the most of your travel budget. #### What is the best airline to fly with from São Tomé? With Expedia, finding the best airline for your journey from São Tomé is a breeze. We offer options from 20 different airlines, including TAAG Angola Airlines, TAP Portugal, ASKY, Ethiopian Airlines. Whether you prioritize price, comfort, or loyalty programs, we have a fit for your travel needs. #### What is the best month to fly from São Tomé? The best month to fly from São Tomé is typically May, as it often offers great deals. If you're looking to save on your journey, start your search with Expedia. We provide options to filter for the lowest possible prices, including those from one-way from CA $351 and roundtrip from CA $793 fares. However, remember that airfare can fluctuate based on the time of year and ticket availability. #### When is the best time to book/buy flights from São Tomé? Secure the best savings with Expedia. Data suggests that booking flights from São Tomé three weeks in advance can save you up to 20%. Also, consider flying in May for the best rates. Stay updated with us for the latest data and savings advice. #### Are there any last-minute flights from São Tomé? With Expedia, finding last-minute flights from São Tomé has never been easier. We offer you a chance to explore the best deals from 20 airlines. Even if you're planning to travel immediately, you can access a variety of options, including one-way from CA $351 and roundtrip from CA $793 fares. Start exploring now and seize the top offers available over the next two weeks. Rest assured, you can find a perfect flight even at the last minute. #### Why book with Expedia? Choose Expedia for unbeatable prices, exceptional value, and substantial savings. We offer a wide selection of routes from São Tomé, with flight options from 20 airlines, including one-way deals from CA $351. Customize your journey to suit your needs and achieve even more savings by bundling your flight with a hotel or car hire. Start planning your trip with us today and earn rewards points with every booking. #### Can I change/cancel my flight? Absolutely, at Expedia, you can change or cancel your flight. However, fees and refund policies depend on your flight agreement, as each airline has distinct rules for exchanges and refunds. For detailed information, check your itinerary or visit our customer service portal. To maximize flexibility, opt for flights with no change fees using our 'Flexible change policies' filter. ## Explore a world of travel with Expedia - Lodging - Flights - Cars ### Lodging - [Hotels near São Tomé Intl.](https://www.expedia.ca/Sao-Tome-Intl-Airport-Hotels.0-aTMS-0.Travel-Guide-Filter-Hotels) - [Vila Maria Hotels](https://www.expedia.ca/Vila-Maria-Sao-Tome-Hotels.0-n553248635976400254-0.Travel-Guide-Filter-Hotels) ### Flights - [Flights from Accra (ACC) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/acc/tms/accra-to-sao-tome-island) - [Flights from Douala (DLA) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/dla/tms/douala-to-sao-tome-island) - [Flights from Johannesburg (JNB) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/jnb/tms/johannesburg-to-sao-tome-island) - [Flights from London (LHR) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/lhr/tms/london-to-sao-tome-island) - [Flights from Lisbon (LIS) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/lis/tms/lisbon-to-sao-tome-island) - [Flights from Edmonton (YEG) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/yeg/tms/edmonton-to-sao-tome-island) - [Flights from Halifax (YHZ) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/yhz/tms/halifax-to-sao-tome-island) - [Flights from Ottawa (YOW) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/yow/tms/ottawa-to-sao-tome-island) - [Flights from Montreal (YUL) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/yul/tms/montreal-to-sao-tome-island) - [Flights from Vancouver (YVR) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/yvr/tms/vancouver-to-sao-tome-island) - [Flights from Winnipeg (YWG) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/ywg/tms/winnipeg-to-sao-tome-island) - [Flights from Calgary (YYC) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/yyc/tms/calgary-to-sao-tome-island) - [Flights from Toronto (YYZ) to São Tomé Island (TMS)](https://www.expedia.ca/lp/flights/yyz/tms/toronto-to-sao-tome-island) ### Cars - [Rental cars São Tomé Intl. airport](https://www.expedia.ca/Car-Rentals-In-Sao-Tome-Intl.d6032497.Car-Rental-Guide) \*Available to Expedia members.