Cheap flights from Minneapolis - St. Paul to Southwest Illinois from CA $121

View CA $121 flight on Sat, Aug. 30, 2025Opens in a new window

Popular airlines from Minneapolis to Southwest Illinois

  • Air Canada

    Air Canada

  • WestJet

    WestJet

  • Flair Airlines

    Flair Airlines

  • American Airlines

    American Airlines

  • United

    United

  • Delta

    Delta

  • Porter Airlines

    Porter Airlines

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Minneapolis - St. Paul (MSP) to Southwest Illinois (STL)

Prices were available within the past 7 days and start at CA $121 for one-way flights and CA $243 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, Aug. 30 - Tue, Sep. 2
MSP
Minneapolis
STL
St. Louis
CA $243 Roundtrip, found 5 days ago
CA $243
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Aug. 30 from Minneapolis to St. Louis, returning Tue, Sep. 2, priced at CA $243 found 5 days ago
American Airlines
Sat, Aug. 30 - Tue, Sep. 2
MSP
Minneapolis
STL
St. Louis
CA $248 Roundtrip, found 5 days ago
CA $248
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Aug. 30 from Minneapolis to St. Louis, returning Tue, Sep. 2, priced at CA $248 found 5 days ago
American Airlines
Sat, Aug. 30 - Tue, Sep. 2
MSP
Minneapolis
STL
St. Louis
CA $252 Roundtrip, found 5 days ago
CA $252
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Aug. 30 from Minneapolis to St. Louis, returning Tue, Sep. 2, priced at CA $252 found 5 days ago
Delta
Sat, Aug. 30 - Tue, Sep. 2
MSP
Minneapolis
STL
St. Louis
CA $258 Roundtrip, found 5 days ago
CA $258
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Aug. 30 from Minneapolis to St. Louis, returning Tue, Sep. 2, priced at CA $258 found 5 days ago
Delta
Fri, Aug. 29 - Sun, Aug. 31
MSP
Minneapolis
STL
St. Louis
CA $268 Roundtrip, found 5 days ago
CA $268
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Aug. 29 from Minneapolis to St. Louis, returning Sun, Aug. 31, priced at CA $268 found 5 days ago
United
Sat, Aug. 30 - Tue, Sep. 2
MSP
Minneapolis
STL
St. Louis
CA $307 Roundtrip, found 5 days ago
CA $307
Roundtrip
found 5 days ago
Select United flight, departing Sat, Aug. 30 from Minneapolis to St. Louis, returning Tue, Sep. 2, priced at CA $307 found 5 days ago
*Available to Expedia members.