Cheap flights from Houston to South San Diego from CA $115

View CA $115 flight on Sat, Aug. 9, 2025Opens in a new window

Popular airlines from Houston to South San Diego

  • American Airlines

    American Airlines

  • Alaska Airlines

    Alaska Airlines

  • Delta

    Delta

  • Spirit Airlines

    Spirit Airlines

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Houston (HOU) to South San Diego (SAN)

Prices were available within the past 7 days and start at CA $115 for one-way flights and CA $255 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Fri, Aug. 29 - Fri, Sep. 5
IAH
Houston
SAN
San Diego
CA $255 Roundtrip, found 2 days ago
CA $255
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Fri, Aug. 29 from Houston to San Diego, returning Fri, Sep. 5, priced at CA $255 found 2 days ago
Hawaiian Airlines
Wed, Sep. 3 - Sat, Sep. 13
IAH
Houston
SAN
San Diego
CA $276 Roundtrip, found 6 days ago
CA $276
Roundtrip
found 6 days ago
Select Hawaiian Airlines flight, departing Wed, Sep. 3 from Houston to San Diego, returning Sat, Sep. 13, priced at CA $276 found 6 days ago
Hawaiian Airlines
Fri, Aug. 22 - Tue, Sep. 9
IAH
Houston
SAN
San Diego
CA $280 Roundtrip, found 6 days ago
CA $280
Roundtrip
found 6 days ago
Select Hawaiian Airlines flight, departing Fri, Aug. 22 from Houston to San Diego, returning Tue, Sep. 9, priced at CA $280 found 6 days ago
United
Tue, Aug. 12 - Sat, Aug. 23
IAH
Houston
SAN
San Diego
CA $313 Roundtrip, found 6 days ago
CA $313
Roundtrip
found 6 days ago
Select United flight, departing Tue, Aug. 12 from Houston to San Diego, returning Sat, Aug. 23, priced at CA $313 found 6 days ago
Delta
Tue, Aug. 12 - Fri, Aug. 22
IAH
Houston
SAN
San Diego
CA $323 Roundtrip, found 6 days ago
CA $323
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Aug. 12 from Houston to San Diego, returning Fri, Aug. 22, priced at CA $323 found 6 days ago
Alaska Airlines
Mon, Aug. 25 - Fri, Aug. 29
IAH
Houston
SAN
San Diego
CA $356 Roundtrip, found 5 days ago
CA $356
Roundtrip
found 5 days ago
Select Alaska Airlines flight, departing Mon, Aug. 25 from Houston to San Diego, returning Fri, Aug. 29, priced at CA $356 found 5 days ago
*Available to Expedia members.