Given the limited tourist infrastructure in Muyinga, the best area to stay is generally within the central part of Muyinga town itself, particularly near the main roads and administrative buildings.
Muyinga is a provincial capital, and the central area is where most of the limited amenities are located. You'll find it's a relatively compact town, with key areas accessible on foot or by local transport. The main thoroughfares, such as the RN6, will have the most accessible guesthouses and places to eat.
For travellers on a business trip or those visiting for community work, staying centrally offers the most convenience. You'll be close to government offices, local markets, and any potential meeting points.