Sikeston Vacation Packages
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Your Sikeston Vacation
There's tons to like about Sikeston, from its rich history to its rural countryside. When you're ready to say hi to this captivating city, our Sikeston vacation packages will be perfect for you. Fill your spare time with visits to Sikeston Depot Museum, The Book Bug and Central Park, some of the top attractions you just have to see during your trip to Sikeston. That dream Sikeston vacation is clicks away. Browse hotels, flights and more on Expedia for a getaway that's tailored to suit your travel style.
Top Sikeston Vacation Deals
Price found within the past 48 hours. Click for updated prices.
The Knight Center at Washington University
Price was CA $1,727, price is now CA $1,366 per person
CA $1,366
per person
Jul 20 - Jul 27
found 14 hours ago
Roundtrip flight included
Toronto (YTO) to St. Louis (STL)
9.4/10 Exceptional! (541 reviews)
Great location and perfect for event at Washington University
Reviewed on May 14, 2026
Hilton Pennywell St. Louis at the Arch
Downtown St. Louis
Price was CA $2,254, price is now CA $1,756 per person
CA $1,756
per person
Jul 20 - Jul 27
found 14 hours ago
Roundtrip flight included
Toronto (YTO) to St. Louis (STL)
8.8/10 Excellent! (1,048 reviews)
Clean rooms and comfortable lounge with friendly staff
Reviewed on May 14, 2026
Hampton Inn By Hilton St Louis Airport
Woodson Terrace
Price was CA $1,966, price is now CA $1,574 per person
CA $1,574
per person
Jul 20 - Jul 27
found 14 hours ago
Roundtrip flight included
Toronto (YTO) to St. Louis (STL)
8.8/10 Excellent! (153 reviews)
Property was in a convenient location. It was well kept
Checkin was fast and efficient. The room was clean and comfortable. The shuttle was timely to the airport.
Reviewed on May 13, 2026
Courtyard by Marriott St. Louis Downtown/Convention Center
Downtown St. Louis
Price was CA $1,883, price is now CA $1,509 per person
CA $1,509
per person
Jul 20 - Jul 27
found 14 hours ago
Roundtrip flight included
Toronto (YTO) to St. Louis (STL)
9/10 Wonderful! (1,015 reviews)
The Breakfast options were good & fairly fast. The room was quiet and bed was comfortable.
Reviewed on May 13, 2026
The Westin St. Louis
Downtown St. Louis
Price was CA $2,200, price is now CA $1,768 per person
CA $1,768
per person
Jul 20 - Jul 27
found 14 hours ago
Roundtrip flight included
Toronto (YTO) to St. Louis (STL)
8.6/10 Excellent! (1,010 reviews)
Valet parking was easy but $50 daily. However very great experience and walk across the street to baseball park. Very friendly staff
Reviewed on May 4, 2026
Sikeston Hotel Deals
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $153 per night from May 31 to Jun 1
CA $153
CA $175 total
May 31 - Jun 1
includes taxes & fees
9.6/10 Exceptional! (1,001 reviews)
Very nice and clean place with courteous staff.
Reviewed on May 13, 2026
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $140 per night from May 31 to Jun 1
CA $140
CA $158 total
May 31 - Jun 1
includes taxes & fees
9/10 Wonderful! (560 reviews)
Everything was good
Reviewed on May 10, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $124 per night from Jun 7 to Jun 8
CA $124
CA $142 total
Jun 7 - Jun 8
includes taxes & fees
8.4/10 Very Good! (1,011 reviews)
The breakfast was really good and having bacon was a nice change. The room was comfortable.
Reviewed on May 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
