The walkable destination of Sanford is a great choice if you’ve been thinking about a vacation with the kids. The entertainment, lake views, and wildlife are just a few things that make this an attractive vacation spot for families. Fly into Orlando Sanford Intl. Airport (SFB), which is the closest airport, or Orlando Intl. Airport (MCO), which is located 25.8 mi (41.5 km) from the city center.