Title: San Domino Vacation Rentals : Short-Term Rentals for 2026 | Expedia.ca [San Domino Travel Guide](https://expedia.ca/San-Domino.dx6125738)[Hotels in San Domino](https://expedia.ca/San-Domino-Hotels.d6125738.Travel-Guide-Hotels)[Flights to San Domino](https://expedia.ca/Cheap-Flights-To-San-Domino.d6125738.Travel-Guide-Flights)[San Domino Car Rentals](https://expedia.ca/Car-Rentals-In-San-Domino.d6125738.Car-Rental-Guide)[San Domino Vacation Packages](https://expedia.ca/San-Domino.d6125738.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6125738&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6125738&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=6125738&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=6125738&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSan-Domino-Vacation-Rentals.d6125738.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSan-Domino-Vacation-Rentals.d6125738.Travel-Guide-VacationRentals) ## Top San Domino Hotel Reviews ![L'ISOLA DEI SAPORI BOUTIQUE HOTEL ](https://images.trvl-media.com/lodging/102000000/101960000/101956900/101956860/413dbf47_y.jpg) ### L'ISOLA DEI SAPORI BOUTIQUE HOTEL 10/10 Excellent "For an off season stay (middle of winter in a beach resort) the staff went out of their way to make us welcome. Looking at the summer amenities it would be a great place for a beach holiday." [](https://expedia.ca/Cagnano-Varano-Hotels-LISOLA-DEI-SAPORI-BOUTIQUE-HOTEL.h101956860.Hotel-Information) ![B&B Aura](https://images.trvl-media.com/lodging/117000000/116220000/116217300/116217270/ecf0cfc0_edited_08f8_y.jpg) ### B&B Aura 10/10 Excellent "quiet place, free parking, everything in the building and rooms is new and clean. We were met personally by Paolo and showed the room. Soundproofing is very poor, but we stayed in October so we were alone. A very good option for one night. Room without windows, good lighting. A town with a beautiful coast and a visible sunset." [](https://expedia.ca/Lesina-Hotels-BB-Aura.h116217270.Hotel-Information) ![Eden](https://images.trvl-media.com/lodging/3000000/2950000/2942300/2942214/5a1faf1a_y.jpg) ### Eden 8/10 Good "Friendly staff, great location. Katia at Reception was amazing " [](https://expedia.ca/Tremiti-Islands-Hotels-Eden.h2942214.Hotel-Information) ## Find out more about San Domino You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded. As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with San Domino. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do. ## Explore a world of travel with Expedia - Trending destinations on Expedia.ca - All accommodation types in San Domino ### Trending destinations on Expedia.ca - [Canmore Vacation Rentals ](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Kelowna Vacation Rentals ](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals) - [Whistler Vacation Rentals ](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Victoria Vacation Rentals ](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals) - [Vancouver Vacation Rentals ](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals) - 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