Title: Book The Best Hotels in Mesopotamia for 2025 from CA $50 - Fully Refundable Options - Expedia.ca [Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides) ![Mesopotamia showing a river or creek and forests](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Mesopotamia from CA $50 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mesopotamia Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&lodging=APART_HOTEL) Spa [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=SPA_ON_SITE) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&lodging=APARTMENT) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=PETS) ## Check prices for these dates Tonight [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 500 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/95a72f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cf8e0206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/138c0f23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hathor Concordia Concordia 8.6/10 Excellent (352) "Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful." CA $69 CA $84 total Sep 28 - Sep 29 [](https://www.expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![43-inch LED TV with digital channels, TV, pay movies](https://images.trvl-media.com/lodging/42000000/41510000/41507100/41507004/fb9f7997.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![43-inch LED TV with digital channels, TV, pay movies](https://images.trvl-media.com/lodging/42000000/41510000/41507100/41507004/f77ff75a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/42000000/41510000/41507100/41507004/a752758e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Cottage, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/42000000/41510000/41507100/41507004/d8107959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Tránsito Hotel Boutique Concepción 10/10 Exceptional (3) "This is an excellent Hotel and experience. The staff is vibrant and attentive. I would rate this hotel as one of the best, if not the best hotel I have ever stayed at. " CA $532 CA $532 total Sep 28 - Sep 29 [](https://www.expedia.ca/Concepcion-Hotels-Hotel-Boutique-El-Transito.h41507004.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/fdcb8515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/c06e65ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/577a600f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### O2 Hotel Gualeguaychú Gualeguaychú 7.6/10 Good (61) "Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. " CA $50 CA $50 total Sep 28 - Sep 29 [](https://www.expedia.ca/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![Indoor pool, 2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/182c3232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/e22e8bc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/a0871cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/384ea822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mayim Hotel Termal & SPA Concordia 9.0/10 Wonderful (4) "Muito bom o hotel. Atendimento excelente e comida também " CA $117 CA $117 total Oct 26 - Oct 27 [](https://www.expedia.ca/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) ![2 bedrooms, hypo-allergenic bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/13800447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/33de7786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/15db4e78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/f0f7bd93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Totoras Apart Federacion Federacion 7.2/10 Good (25) "Buena estadia para unos dias .todo muy limpio a pesar de que estan aun terminando dptos.tal vez deben cuidar más los horarios de descanso del turista con los ruidos de la obra . Pocos utensilios de cocina si se quiere cocinar ahi mismo.Pero tranquilo y suficiente" CA $35 CA $35 total Sep 28 - Sep 29 [](https://www.expedia.ca/Federacion-Hotels-Totoras-Apart-Federacion.h33341429.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/115000000/114350000/114341100/114341005/92208950.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114350000/114341100/114341005/ebb3bbdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/115000000/114350000/114341100/114341005/caa3d299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/115000000/114350000/114341100/114341005/876a16f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### COSTA NORTE HOSTERIA Colón CA $77 CA $77 total Oct 3 - Oct 4 [](https://www.expedia.ca/Colon-Hotels-COSTA-NORTE-HOSTERIA.h114341005.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/03c0216a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/386d872f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/2caaf7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Corrientes Hotel Corrientes CA $187 CA $187 total Oct 3 - Oct 4 [](https://www.expedia.ca/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/eaf0483c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rollaway beds, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/5b08b016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/8e6becd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/ad6c99f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Posada Che Teindy Colonia Carlos Pellegrini CA $137 CA $137 total Oct 15 - Oct 16 [](https://www.expedia.ca/Colonia-Carlos-Pellegrini-Hotels-Posada-Che-Teindy.h38300196.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/459986e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/db430021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/e70d9e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/dd41bc20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Spa Termas del Este Federacion 8.4/10 Very good (12) "good for a 1 night stay" CA $74 CA $74 total Sep 28 - Sep 29 [](https://www.expedia.ca/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/111000000/110440000/110434900/110434860/546d1171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LED TV with cable channels](https://images.trvl-media.com/lodging/111000000/110440000/110434900/110434860/49aabb1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Quadruple Room | Living area](https://images.trvl-media.com/lodging/111000000/110440000/110434900/110434860/fc0176c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/111000000/110440000/110434900/110434860/ed8c82be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Hotel Federacion 2.0/10 (1) "Ambiente deixa a desejar, muito sujo, café da manhã ruim, sem opção. Baratas no ambiente." CA $62 CA $62 total Sep 28 - Sep 29 [](https://www.expedia.ca/Federacion-Hotels-Urban-Hotel.h110434860.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, body treatments, hot stone massages, facials](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/ef76fc3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/c45620e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/96c73453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Costarenas Hotel & Spa Colon 8.6/10 Excellent (57) CA $169 CA $169 total Sep 29 - Sep 30 [](https://www.expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/750a674d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/f32e7494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/60e3bf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Valle Termal Resort Federacion 9.2/10 Wonderful (93) CA $46 CA $46 total Sep 28 - Sep 29 [](https://www.expedia.ca/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/a2d4eb00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/c1286a77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cdd97d7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Intersur Colon Colón 10/10 Exceptional (2) "Letti molto comodi, belle piscine, personale gentile, pulizia buona, colazione buona. Ottimo rapporto qualità prezzo. " CA $146 CA $146 total Sep 28 - Sep 29 [](https://www.expedia.ca/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/fb045420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/b6d8eda3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/7aefeb63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Triple Room](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/92bac361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donsuites Apart Hotel Corrientes 8.6/10 Excellent (104) "Loved this place, super clean, and the staff were very nice and helpful😍" CA $101 CA $101 total Sep 28 - Sep 29 [](https://www.expedia.ca/Corrientes-Hotels-Donsuites-Apart-Hotel.h4947848.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/bc43cf92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/w717h717x3y0-ae142680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/35e5a3fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/3ef0a127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa del Árbol Concepción del Uruguay 8.0/10 Very good (7) "La primera vez que venga a Concepcion del Uruguay, quiero alquilar en" la casa del arbol" Me sentí muy bienvenida y en buena compañía, los anfitriones son maravillosos " CA $33 CA $33 total Sep 28 - Sep 29 [](https://www.expedia.ca/Concepcion-Del-Uruguay-Hotels-Casa-Del-Arbol.h36653372.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/b3e275d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/0323f4ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/216c6bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room (VIP) | Jetted tub](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/ea0ac718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bungalows Mexico Concepción del Uruguay 8.8/10 Excellent (12) "Local estava limpo, a cama é ótima, mas o banheiro a água n esquentava. O atendimento foi bom, são atenciosos. " CA $58 CA $58 total Sep 27 - Sep 28 [](https://www.expedia.ca/Concepcion-Del-Uruguay-Hotels-Bungalows-Mexico.h15363214.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c114ee3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c58abaf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c058d200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/3140cd55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Alondra Casa De Huéspedes Corrientes 9.2/10 Wonderful (65) CA $173 CA $173 total Oct 16 - Oct 17 [](https://www.expedia.ca/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/77b70130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/6a6d02f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Double Room](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/4e070a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/908e21a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Maran Suites & Towers - Hotel & Spa Parana 9.0/10 Wonderful (30) "Great location and friendly, accommodating staff. " CA $115 CA $115 total Oct 1 - Oct 2 [](https://www.expedia.ca/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information) ![2 bedrooms, premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/9cad496d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment | Private kitchen](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/3ee5dbf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Duplex | Living area](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/1eee7dc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment | Living area](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/1f4c0785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Agustín 1 Apart Parana 9.0/10 Wonderful (4) CA $75 CA $75 total Sep 29 - Sep 30 [](https://www.expedia.ca/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information) ![Seasonal outdoor pool, open noon to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/5000000/4420000/4411700/4411601/456e237c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 3 per person)](https://images.trvl-media.com/lodging/5000000/4420000/4411700/4411601/01834db8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/5000000/4420000/4411700/4411601/d89014ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4420000/4411700/4411601/59acb415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Casona de Susana Colon 7.4/10 Good (25) CA $58 CA $58 total Sep 27 - Sep 28 [](https://www.expedia.ca/Colon-Hotels-La-Casona-De-Susana.h4411601.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11®ionId=6208836&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Mesopotamia Showing deals for:Oct 3 - Oct 5 ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/b3e275d5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Bungalows Mexico Concepción del Uruguay 8.8/10Excellent (12 reviews) 11% off CA $82 CA $164 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=15363214&adults=2) ![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hathor Concordia Concordia 8.6/10Excellent (352 reviews) 10% off CA $105 CA $210 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=4668235&adults=2) ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Intersur Colon Colon 10/10Exceptional (2 reviews) Member Price available CA $160 CA $321 total [Sign in for Member Price](https://www.expedia.ca/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-10-03%26endDate%3D2025-10-05%26selected%3D114109755%26adults%3D2) [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=114109755&adults=2) ![43-inch LED TV with digital channels, TV, pay movies](https://images.trvl-media.com/lodging/42000000/41510000/41507100/41507004/fb9f7997.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### El Tránsito Hotel Boutique Concepción 10/10Exceptional (3 reviews) 10% off CA $720 CA $1,440 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=41507004&adults=2) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c114ee3f.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### La Alondra Casa De Huéspedes Corrientes 9.2/10Wonderful (65 reviews) 20% off CA $213 CA $426 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=2803582&adults=2) ![Exterior](https://images.trvl-media.com/lodging/106000000/105130000/105127300/105127292/19db5632.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Estancia La Violeta Chajarí 8.8/10Excellent (3 reviews) 10% off CA $176 CA $351 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=105127292&adults=2) ![Exterior](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/459986e2.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel y Spa Termas del Este Federacion 8.4/10Very good (12 reviews) 20% off CA $82 CA $164 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=33346911&adults=2) ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Club Valle Termal Resort Federacion 9.2/10Wonderful (93 reviews) Member Price available CA $57 CA $114 total [Sign in for Member Price](https://www.expedia.ca/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-10-03%26endDate%3D2025-10-05%26selected%3D11875903%26adults%3D2) [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=11875903&adults=2) ![Premium bedding, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/e2c6f8db.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Rio Chajarí 8.8/10Excellent (11 reviews) 10% off CA $100 CA $201 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=36908421&adults=2) ![2 bedrooms, premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/9cad496d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Agustín 1 Apart Parana 9.0/10Wonderful (4 reviews) 10% off CA $100 CA $201 total [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-05&selected=99269311&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6208836.Travel-Guide-Hotels) ## Learn more about Mesopotamia The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration. [See all hotels in Mesopotamia](https://www.expedia.ca/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11&adults=2®ionId=6208836) ![Mesopotamia showing a river or creek and forests](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/196000/196544-Mesopotamia.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ### Stay near popular Mesopotamia attractions [](https://expedia.ca/Victoria-Beach-Hotels.0-l6250473-0.Travel-Guide-Filter-Hotels) #### Victoria Beach If a restful vacation is part of your travel plans, Victoria Beach might be the perfect place to seek out during your trip to Victoria. Make some time to visit the monuments while you're in the area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6250473) ## More cheap stays in Mesopotamia ![Mediterraneo Hotel](https://images.trvl-media.com/lodging/79000000/78400000/78398800/78398800/e5c9471d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Mediterraneo Hotel 1510 Corrientes, Rosario, Santa Fe [Get rates](https://expedia.ca/Hotel-Search?startDate=10%2F10%2F2025&endDate=11%2F10%2F2025&selected=78398800&PinnedHotelID=78398800&HadPinnedHotel=true®ionId=6208836) 10/10 Exceptional! (5 reviews) [](https://expedia.ca/Rosario-Hotels-Mediterraneo-Hotel.h78398800.Hotel-Information) ![O2 Hotel Gualeguaychú](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### O2 Hotel Gualeguaychú 115 3 de Febrero, Gualeguaychú, Entre Ríos CA $50 CA $50 total Sep 28 - Sep 29 7.6/10 Good! (61 reviews) [](https://expedia.ca/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![Niyat Urban Hotel](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363217/4495f2cc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Niyat Urban Hotel Hipolito Yrigoyen 83, Resistencia, Chaco Province [Get rates](https://expedia.ca/Hotel-Search?startDate=10%2F10%2F2025&endDate=11%2F10%2F2025&selected=15363217&PinnedHotelID=15363217&HadPinnedHotel=true®ionId=6208836) 8/10 Very Good! (6 reviews) [](https://expedia.ca/Resistencia-Hotels-Niyat-Urban-Hotel.h15363217.Hotel-Information) ![Hosteria Maryland](https://images.trvl-media.com/lodging/29000000/28960000/28950500/28950437/7d1617a4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hosteria Maryland AV. FRANCISCO DE HARO 3569, Posadas CA $50 CA $53 total Sep 27 - Sep 28 6.8/10 (28 reviews) [](https://expedia.ca/Posadas-Hotels-Hosteria-Maryland.h28950437.Hotel-Information) ![Apart Hotel Las Violetas](https://images.trvl-media.com/lodging/92000000/91280000/91272000/91271956/0b3e9773_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Apart Hotel Las Violetas Barrio del Lago, 3008, Candelaria, Misiones [Get rates](https://expedia.ca/Hotel-Search?startDate=10%2F10%2F2025&endDate=11%2F10%2F2025&selected=91271956&PinnedHotelID=91271956&HadPinnedHotel=true®ionId=6208836) [](https://expedia.ca/Candelaria-Hotels-Apart-Hotel-Las-Violetas.h91271956.Hotel-Information) ![Hostal Santa Fe de la Veracruz ](https://images.trvl-media.com/lodging/5000000/4410000/4404900/4404816/bd301f09_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hostal Santa Fe de la Veracruz San Martin 2954, Santa Fe, Santa Fe [Get rates](https://expedia.ca/Hotel-Search?startDate=10%2F10%2F2025&endDate=11%2F10%2F2025&selected=4404816&PinnedHotelID=4404816&HadPinnedHotel=true®ionId=6208836) [](https://expedia.ca/Santa-Fe-Hotels-Hostal-Santa-Fe-De-La-Veracruz.h4404816.Hotel-Information) ## Hotels in Mesopotamia with star-rating ![5 Star Hotels](https://images.trvl-media.com/lodging/5000000/4390000/4388000/4387932/5e4f0852_w.jpg) 5 Star Hotels 1 properties [](https://expedia.ca/5Star-Mesopotamia-Hotels.s50-0-d6208836.Travel-Guide-Filter-Hotels) ![4 Star Hotels](https://images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/36b8ac51_w.jpg) 4 Star Hotels 16 properties [](https://expedia.ca/4Star-Mesopotamia-Hotels.s40-0-d6208836.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_w.jpg) 3 Star Hotels 163 properties [](https://expedia.ca/3Star-Mesopotamia-Hotels.s30-0-d6208836.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/79000000/78400000/78398800/78398800/e5c9471d_w.jpg) 2 Star Hotels 155 properties [](https://expedia.ca/2Star-Mesopotamia-Hotels.s20-0-d6208836.Travel-Guide-Filter-Hotels) ## Find out more about Mesopotamia ### Top reasons to visit Mesopotamia - **Scenic National Parks:** Explore stunning national parks with breathtaking mountain views and lush landscapes, perfect for nature lovers. - **Outdoor Adventures:** Engage in exciting activities like hiking, birdwatching, and water parks, catering to both thrill-seekers and families. - **Charming Neighbourhoods:** Stroll through romantic neighbourhoods like Bahcamatiate and Midyat, offering a delightful atmosphere. - **Family-Friendly Activities:** Enjoy a variety of attractions designed for family vacations that ensure fun for all ages. - **Comfortable Accommodations:** Stay in diverse hotel options, from cozy retreats to luxurious facilities, ensuring a memorable experience. ### Find great hotels near Mesopotamia Discover a variety of hotel accommodations in Mesopotamia, Argentina, designed for families seeking unforgettable vacations. From cozy retreats to top-notch star-rated facilities, you’ll find options that suit every traveller's needs. Whether you're looking for the best hotels or a tranquil stay at the Calma Hotel, Mesopotamia offers a welcoming atmosphere and essential amenities to make your stay memorable. - **[El Tránsito Hotel Boutique:](https://www.expedia.ca/Concepcion-Hotels-Hotel-Boutique-El-Transito.h41507004.Hotel-Information)** Nestled 29.0km from Mesopotamia, El Tránsito Hotel Boutique offers a charming family-friendly atmosphere perfect for a memorable vacation. This 3.5-star hotel is designed with families in mind, featuring an Arcade Game Room, a children's pool, and complimentary cribs. Guests appreciate the inviting ambiance, attentive service, and amenities tailored for kids, ensuring a delightful stay for both parents and children. Embrace the warmth of Argentinian hospitality while enjoying a peaceful retreat at this lovely boutique hotel. ### Where to stay near Mesopotamia Mesopotamia, Argentina, offers an exciting blend of adventure and relaxation for every family. Discover the breathtaking mountain views while exploring the scenic trails and lush landscapes nearby. The charming neighborhoods, like Bahcamatiate and Midyat, provide a romantic backdrop for leisurely strolls. Whether you're hiking or enjoying outdoor activities, the region promises an unforgettable experience that combines natural beauty with family-friendly fun. - **[Mercedes:](https://www.expedia.ca/Mercedes-Hotels.d6338887.Travel-Guide-Hotels)** Nestled 49.9km from Mesopotamia, Mercedes is a vibrant city that offers a delightful mix of outdoor adventures and family-friendly experiences. Visitors are drawn to its national state park, water park, and theme park, making it an ideal destination for thrill-seekers and nature lovers alike. The city sees a surge in tourist activity during July and the festive season from December to January, but it's a year-round destination for those seeking adventure. Whether you're swinging a club at a local golf course or splashing around at the water park, Mercedes promises an exhilarating getaway. - **[Concepción:](https://www.expedia.ca/Concepcion-Hotels.d553248635924012399.Travel-Guide-Hotels)** Located 35.4km from Mesopotamia, Concepción is a picturesque city perfect for outdoor enthusiasts and those seeking scenic beauty. The city's allure peaks in April, July, and September, attracting visitors keen on exploring its national state park and surrounding natural parks. With ample opportunities for hiking and sightseeing, Concepción invites you to immerse yourself in its stunning landscapes. The relatively stable visitor numbers throughout the year mean you can enjoy a quieter experience while still indulging in its natural charm. - **Uguay:** Just 27.4km from Mesopotamia, Uguay is a quaint village that embodies the essence of tranquil rural life. Known for its seasonal visitor influx, peaking in January, March, and November, Uguay is a haven for nature lovers. The nearby natural parks provide a serene backdrop for leisurely hikes and picnics amidst stunning landscapes. If you’re looking for a slow-paced escape from the hustle and bustle of city life, Uguay offers a peaceful retreat that celebrates the beauty of the great outdoors. ### Things to do in Mesopotamia Mesopotamia, Argentina, offers a variety of activities perfect for family and adventure vacations. Visitors can enjoy exciting attractions such as water parks, birdwatching, and scenic hiking trails. This diverse region ensures a memorable experience for tourists seeking both relaxation and outdoor fun. **Shopping** In Mesopotamia, you can explore shopping at the Shopping del Sol, featuring popular brands and local boutiques. For a more traditional experience, visit the Mercado Municipal, where you’ll find unique handicrafts and delicious regional foods, perfect for gifts and souvenirs. **Recreation** Experience a tranquil stay at Termas de Río Hondo, where you can indulge in natural thermal baths and rejuvenating spa treatments. For recreation, explore the lush landscapes on horseback or enjoy leisurely walks along the scenic riverside, immersing yourself in the serene beauty of Mesopotamia. **Adventure** Explore the stunning Ibera Wetlands, home to diverse wildlife, by canoe or kayak. Experience thrilling hikes through lush landscapes at Quebrada de Humahuaca, where you can marvel at vibrant rock formations and learn about the region's rich cultural heritage. **Nightlife** The nightlife in Mesopotamia, Argentina, is vibrant and diverse. Enjoy a lively evening at local bars like El Club de la Cerveza for craft brews, or dance the night away at La Fiesta, where live music creates an electrifying atmosphere. Experience the unique culture and warm hospitality of the region. *\*Distances are measured in a straight line; actual driving distances may vary depending on the route.* ### Booking tips and Expedia advantages for Mesopotamia When planning your trip to Mesopotamia, Argentina, consider visiting during the off-peak months for lower prices, avoiding July, August, and December. Book accommodations about a month in advance or check Expedia's last-minute deals for savings. Tuesdays are the best days for cheaper stays, while Mondays tend to be pricier. Use Expedia’s search tools to filter for budget-friendly and eco-certified options, and consider bundling your hotel, flights, and activities for additional discounts. Look out for free activities in the area to maximize your enjoyment without breaking the bank. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Mesopotamia are , where the prices are slightly lower. This is in comparison to July to August and December, where prices are slightly higher. - **The best time to book a hotel:** The cheapest time to book a hotel around Mesopotamia is usually 1 month out from when you are planning to stay. If you're a little more spontaneous, you could also peruse Expedia's last minute deals which could secure you a cheaper stay. Look out for the green banner below the price to spot the deals. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Mesopotamia is Tuesday. The most expensive day to stay around Mesopotamia is Monday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to refine your preferences, such as your budget, preferred location, and the type of hotel you desire. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly accommodations currently available. To discover the best prices and deals, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save some money by combining your hotel reservations in Mesopotamia with your flights and activities through an Expedia package. ### Find the best attractions near Mesopotamia Mesopotamia, Argentina, offers a fantastic blend of entertainment, adventure, and family-friendly activities. Explore stunning national parks and enjoy the breathtaking scenery while engaging in outdoor experiences that cater to thrill-seekers and nature lovers alike. With a variety of points of interest, your vacation in Mesopotamia promises unforgettable adventures for all types of travelers. - **Portal Carambola:** Located 22.5km from Mesopotamia, this national park offers thrilling adventures amidst stunning scenery and a vibrant outdoor atmosphere, perfect for nature enthusiasts seeking unique experiences in Argentina. ### Best time to go to Mesopotamia The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 80.1°F (26.700000000000003°C) | Light Rain | Sunny | Moderately High | Average | | February | 77.7°F (25.4°C) | Light Rain | Mostly Sunny | | March | 72.9°F (22.700000000000003°C) | Light Rain | Mostly Sunny | Moderately High | Average | | April | 66.7°F (19.3°C) | Light Rain | Mostly Sunny | Average | Average | | May | 59.5°F (15.3°C) | Light Rain | Mostly Sunny | | June | 60.1°F (15.6°C) | Light Rain | Mostly Sunny | | July | 53.4°F (11.9°C) | Light Rain | Mostly Sunny | Average | Slightly High | | August | 63.7°F (17.6°C) | Light Rain | Mostly Sunny | Average | Slightly High | | September | 60.6°F (15.9°C) | Light Rain | Mostly Sunny | Average | Average | | October | 65.8°F (18.8°C) | Light Rain | Mostly Sunny | Average | Average | | November | 72.3°F (22.4°C) | Light Rain | Sunny | Moderately High | Average | | December | 77.0°F (25.0°C) | Light Rain | Sunny | Average | Slightly High | ### The nearest major airports for your trip to Mesopotamia To reach Mesopotamia, Argentina, you can fly into three major airports. Posadas (PSS-Libertador General Jose de San Martin) is 222.1km away, with nearby hotels such as [La Mision Posadas Hotel](https://www.expedia.ca/Posadas-Hotels-La-Mision-Posadas-Hotel.h4190115.Hotel-Information) and [Continental Posadas Hotel](https://www.expedia.ca/Posadas-Hotels-Continental-Posadas-Hotel.h24990493.Hotel-Information) both offering airport transportation services. Resistencia (RES-Resistencia Intl.) is located 181.9km from Mesopotamia, featuring hotels like [Gala Hotel y Convenciones](https://www.expedia.ca/Resistencia-Hotels-Gala-Hotel-Y-Convenciones.h12370608.Hotel-Information), which also provides transport. Corrientes (CNQ-Corrientes Intl.) is the closest at 164.2km, with options including [La Alondra Casa De Huéspedes](https://www.expedia.ca/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) and [Turismo Hotel Casino](https://www.expedia.ca/Corrientes-Hotels-Turismo-Hotel-Casino.h11901090.Hotel-Information), both offering airport shuttle services. Each airport provides convenient access to the charming attractions of Mesopotamia. ## Recent reviews of Mesopotamia hotels ![Costarenas Hotel & Spa](//images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01_y.jpg) ### Costarenas Hotel & Spa 1/5 Terrible Motel masquerading as a SPA Hotel "Short Version See pictures for detailed information) - Rooms and bathrooms are small, shower already tight spaced with doors that don’t close properly. - By day 3, construction noise and chemicals smells from remodeling work became a big issue. - Receptionist did not offer solutions and lied about remodeling hours. Felt uncomfortable when asked for manager’s name, and refused to give any other information. - Same receptionist reached out later to apologize and acknowledged we should have not been placed in those rooms to begin with. Offered to move us to “upgraded” rooms. - “Upgraded” rooms were even worse. One of the rooms was directly under the ones being remodeled and worked on. Noise began at 8 AM - The other two rooms did not have a functioning air conditioner. Staff gave poor excuse and just said to open windows. There’s tons of noise far into the night from motor bikes and people playing music right across the hotel. - Hotel breakfast was motel level at best. You get eggs swimming in water and some cut up ham. Toasters barely worked, and when staff was asked for replacement they appeared completely clueless. - The spa experience was good when it came to the massage. However “quiet” policy is not enforced and hearing toilets go off right next to the spa area don’t help with the experience. - Check out was the final straw. Desk staff was rude and dismissive of concerns, stating that the room “upgrade” was sufficient compensation for the troubles. " A verified traveller stayed at Costarenas Hotel & Spa Posted 2 weeks ago [](https://expedia.ca/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) ![Holiday Inn Rosario by IHG](//images.trvl-media.com/lodging/1000000/580000/570400/570357/61653463_y.jpg) ### Holiday Inn Rosario by IHG 5/5 Excellent "Todo perfecto " A verified traveller stayed at Holiday Inn Rosario by IHG Posted 1 month ago [](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Rosario.h570357.Hotel-Information) ![Holiday Inn Express Rosario by IHG](//images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg) ### Holiday Inn Express Rosario by IHG 5/5 Excellent "Very clean and spacious. Hearty breakfast. Very courteous staff" A verified traveller stayed at Holiday Inn Express Rosario by IHG Posted 1 month ago [](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information) ![Esplendor by Wyndham Savoy Rosario](//images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/36b8ac51_y.jpg) ### Esplendor by Wyndham Savoy Rosario 5/5 Excellent "Excellent hotel Everything very comfortable, and convenient" A verified traveller stayed at Esplendor by Wyndham Savoy Rosario Posted 2 months ago [](https://expedia.ca/Rosario-Hotels-Esplendor-By-Wyndham-Savoy-Rosario.h2803473.Hotel-Information) ![Dazzler by Wyndham Rosario](//images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/65a9aa22_y.jpg) ### Dazzler by Wyndham Rosario 5/5 Excellent Buena eleccion en Rosario "Todo correcto" A verified traveller stayed at Dazzler by Wyndham Rosario Posted 2 months ago [](https://expedia.ca/Rosario-Hotels-Dazzler-By-Wyndham-Rosario.h20265319.Hotel-Information) ![Howard Johnson by Wyndham Rosario](//images.trvl-media.com/lodging/14000000/13520000/13514300/13514290/3d666cad_y.jpg) ### Howard Johnson by Wyndham Rosario 5/5 Excellent Cómodo "Super conveniente por precio y calidad." A verified traveller stayed at Howard Johnson by Wyndham Rosario Posted 6 months ago [](https://expedia.ca/Rosario-Hotels-Howard-Johnson-Rosario.h13514290.Hotel-Information) ![O2 Hotel Gualeguaychú](//images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8_y.jpg) ### O2 Hotel Gualeguaychú 4/5 Good "Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. " A verified traveller stayed at O2 Hotel Gualeguaychú Posted 10 months ago [](https://expedia.ca/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![Hathor Concordia](//images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg) ### Hathor Concordia 5/5 Excellent "Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful." A verified traveller stayed at Hathor Concordia Posted 10 months ago [](https://expedia.ca/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![Days Inn by Wyndham Zarate](//images.trvl-media.com/lodging/72000000/71050000/71042900/71042838/153bae1a_y.jpg) ### Days Inn by Wyndham Zarate 3/5 Okay "Room with very comfortable beds, which is the hotel's strongest point, service by the guys at breakfast very bad, no desire to work, bathroom located on the ground floor with a smell worse than a public bathroom in the city center, where I have already informed the management so that they can take action. Very nice pool for families. Good hotel for families on vacation and good breakfast!" A verified traveller stayed at Days Inn by Wyndham Zarate Posted 10 months ago [](https://expedia.ca/Zarate-Hotels-Days-Inn-Zarate.h71042838.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mesopotamia. ### How can I save on a Mesopotamia hotel booking with Expedia? > Before booking your Mesopotamia hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Mesopotamia hotel? > Prices for hotels in Mesopotamia often vary, but you can find a great deal from CA $50 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - More ways to book - [Book Hotels in Mesopotamia on Expedia.com.ar](https://www.expedia.com.ar/Mesopotamia-Hoteles.d6208836.Guia-de-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)