A river winding through a dense forest.

Find hotels in Mesopotamia from CA $49

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mesopotamia hotels

Hathor Concordia

Hathor Concordia
3.0 star property
Concordia
8.6 out of 10, Excellent, (380 reviews)
"Hotel excelente "
Brazil
Ivon
The price is CA $77
CA $93 total
Jul 7 - Jul 8
Hathor Concordia

Turismo Hotel Casino

Turismo Hotel Casino
3.0 star property
Corrientes
9.0 out of 10, Wonderful, (7 reviews)
"Boa infraestrutura, e localização!"
Brazil
D. Omar
The price is CA $125
CA $125 total
Jul 13 - Jul 14
Turismo Hotel Casino

Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
3.0 star property
Concordia
9.4 out of 10, Exceptional, (9 reviews)
"Muy bien las piscinas, excelente el personal y la comida del hotel "
Costa Rica
Federico
The price is CA $157
CA $157 total
Jul 8 - Jul 9
Mayim Hotel Termal & SPA

Marriott Corrientes Hotel

Marriott Corrientes Hotel
4.5 star property
Corrientes
9.8 out of 10, Exceptional, (39 reviews)
"Fantastic stay. Room was immaculate and hotel staff were very friendly and helpful. Great pool and beds were super comfortable."
Australia
Marcus
The price is CA $192
CA $192 total
Jul 26 - Jul 27
Marriott Corrientes Hotel

Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
3.5 star property
Parana
9.0 out of 10, Wonderful, (34 reviews)
"Great location and friendly, accommodating staff. "
United States
Michael
The price is CA $147
CA $147 total
Jul 8 - Jul 9
Maran Suites & Towers - Hotel & Spa

Rio Arriba Suites Apartments y Resto

Rio Arriba Suites Apartments y Resto
3.5 star property
Bella Vista
8.6 out of 10, Excellent, (4 reviews)
"Pessoal da recepção excelente acolhimento. Hotel bonito, falta manutenção em certos lugares. Quarto ótimo, cama com colchão selado e barulho nos ares condicionados. Café da manhã deixa a desejar. Restaurante muito bonito. "
Brazil
Anonymous traveller
The price is CA $83
CA $83 total
Jul 19 - Jul 20
Rio Arriba Suites Apartments y Resto

Costarenas Hotel & Spa

Costarenas Hotel & Spa
3.5 star property
Colon
8.8 out of 10, Excellent, (64 reviews)
"spectacular since we arrived the tstaff was wonderful and kind to us very helpful and nice answering all our questions, the hotel very comfortable!! the river view stunning"
Argentina
Lisette
The price is CA $172
CA $172 total
Jul 8 - Jul 9
Costarenas Hotel & Spa

La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes
4.0 star property
Corrientes
9.4 out of 10, Exceptional, (72 reviews)
"Todo excelente "
Mexico
Arturo Oscar
The price is CA $145
CA $145 total
Jul 12 - Jul 13
La Alondra Casa De Huéspedes

Hotel Crespo

Hotel Crespo
3.0 star property
Crespo
10.0 out of 10, Exceptional, (1 review)
The price is CA $57
CA $57 total
Jul 18 - Jul 19
Hotel Crespo

Club Valle Termal Resort

Club Valle Termal Resort
3.0 star property
Federacion
9.2 out of 10, Wonderful, (94 reviews)
"La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto."
United States
Fernando
The price is CA $73
CA $73 total
Aug 1 - Aug 2
Club Valle Termal Resort

La Regina Lodge

La Regina Lodge
4.0 star property
Municipo de Itati
9.0 out of 10, Wonderful, (2 reviews)
"Excelente pousada, piscina fantástica com visual do rio"
Brazil
Marcos
The price is CA $84
CA $84 total
Jul 3 - Jul 4
La Regina Lodge

Hotel Rio

Hotel Rio
3.0 star property
Chajarí
8.8 out of 10, Excellent, (11 reviews)
"Lindo hotel, moderno, limpio, buena atencion, sumaria opciones saladas en el desayuno, como huevos revueltos."
Argentina
SANTIAGO
The price is CA $161
CA $161 total
Jul 6 - Jul 7
Hotel Rio

Bungalows Mexico

Bungalows Mexico
2.5 star property
Concepción del Uruguay
8.8 out of 10, Excellent, (13 reviews)
"Local estava limpo, a cama é ótima, mas o banheiro a água n esquentava. O atendimento foi bom, são atenciosos. "
Brazil
Eduardo
The price is CA $64
CA $64 total
Jul 19 - Jul 20
Bungalows Mexico

Intersur Colon

Intersur Colon
3.0 star property
Colón
8.0 out of 10, Very good, (8 reviews)
"Is ok "
United States
Carla
The price is CA $121
CA $121 total
Jul 12 - Jul 13
Intersur Colon

Estancia Iberá

Estancia Iberá
3.0 star property
Mercedes
10.0 out of 10, Exceptional, (1 review)
"we had a wonderful experience the staff was very friendly and helpful and took us out on lots of activities and we saw an amazing amount of wildlife in a very short period of time. The place is very beautiful and tranquil. I would highly recommend it and give it five stars. "
Canada
orit
The price is CA $161
CA $161 total
Aug 1 - Aug 2
Estancia Iberá

Posada Che Teindy

Posada Che Teindy
2.5 star property
Colonia Carlos Pellegrini
10.0 out of 10, Exceptional, (1 review)
"La posada estaba bien limpia y mantenida tal cual sale en las fotos Sería bueno que le hicieran una piscina ya que desde el mediodía hasta las cuatro de la tarde no hay mucho que hacer debido al calor Gracias "
Mexico
Ricardo
The price is CA $180
CA $180 total
Jul 8 - Jul 9
Posada Che Teindy

Complejo La Loma

Complejo La Loma
3.0 star property
Federacion
8.6 out of 10, Excellent, (7 reviews)
"Had a very good experience here. Hosts do not speak English, but were very patient with me as I used Google Translate to communicate. Woman at the desk was very kind. I had arrived late and was able to check in without issue. The suite is great - there is a full bathroom, bedroom and kitchen / dining area. There is a communal pool outside in the courtyard as well with lounge chairs. Breakfast was decent as well. Parking on site. I would stay here again for sure, but would be better for multiple...
Canada
Logan
The price is CA $50
CA $52 total
Jul 4 - Jul 5
Complejo La Loma

Nandereta Lodge

Nandereta Lodge
2.5 star property
Colonia Carlos Pellegrini
The price is CA $364
CA $364 total
Jul 3 - Jul 4
Nandereta Lodge

Complejo Anjana

Complejo Anjana
3.5 star property
Federación
The price is CA $122
CA $122 total
Aug 1 - Aug 2
Complejo Anjana

Hotel y Spa Termas del Este

Hotel y Spa Termas del Este
3.0 star property
Federacion
8.6 out of 10, Excellent, (13 reviews)
"good for a 1 night stay"
Canada
Chase
The price is CA $78
CA $78 total
Jul 13 - Jul 14
Hotel y Spa Termas del Este
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Mesopotamia

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Mesopotamia attractions

Learn more about Mesopotamia

The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

A waterfall surrounded by dense forest and small islands.

Top Mesopotamia Hotel Reviews

More cheap stays in Mesopotamia

Hotels in Mesopotamia with star rating

Find out more about Mesopotamia

Top reasons to visit Mesopotamia

  • Stunning Natural Landscapes: Mesopotamia boasts breathtaking mountain views and lush scenery, perfect for nature enthusiasts.
  • Outdoor Adventures: Engage in birdwatching, hiking, and wildlife exploration for an adrenaline-packed experience.
  • Charming Neighborhoods: Explore vibrant cities and delightful neighbourhoods that offer unique local shopping and dining.
  • Family-Friendly Accommodations: Enjoy a variety of comfortable hotels designed to cater to families and travellers alike.
  • Serene Picnic Spots: Relax in picturesque locations ideal for unwinding and enjoying the natural beauty.

Find great hotels near Mesopotamia

Discover delightful accommodations in Mesopotamia, Argentina, where family-friendly hotels cater to every traveler's needs. Whether you're seeking a cozy retreat or a vibrant family vacation experience, the area boasts a variety of options to suit your preferences. Explore the best hotels and services designed to make your stay comfortable and memorable in this charming region.

  • El Tránsito Hotel Boutique: El Tránsito Hotel Boutique is a charming 3.5-star accommodation with a stellar guest rating of 10.0, located 29.0km from Mesopotamia. This family-friendly hotel offers a delightful vacation experience with amenities tailored for children, including an arcade game room and a pool specifically designed for kids. Families will appreciate the free cribs available, ensuring a comfortable stay for guests of all ages. With its focus on providing a warm and welcoming atmosphere, El Tránsito Hotel Boutique is an ideal choice for family getaways in Argentina.

Where to stay near Mesopotamia

Mesopotamia, Argentina, is a captivating destination for adventure seekers and families alike. Explore the lush landscapes and serene rivers that define the region, perfect for outdoor excursions and relaxation. Discover nearby charming towns and enjoy local accommodations that reflect the area’s rich culture. Don’t miss the opportunity to unwind at scenic spots, or embark on thrilling adventures that showcase the stunning scenery and vibrant atmosphere of this unique part of Argentina.

  • Mercedes: Located 49.9km from Mesopotamia, Mercedes is an inviting city that offers a blend of outdoor adventure and family-friendly activities. The city is known for its scenic landscapes and vibrant atmosphere, making it a perfect destination for those seeking exploration. Visitors can enjoy popular activities such as golfing and visits to the nearby water park. The local attractions, including a national state park and a theme park, provide ample opportunities for adventure and relaxation. With peak travel months in July and December to January, Mercedes welcomes tourists year-round, ensuring a lively experience no matter when you visit.
  • Concepción: Situated 35.4km away from Mesopotamia, Concepción is a charming city famed for its stunning scenery and outdoor experiences. This destination attracts adventure seekers and nature lovers alike, with peak travel periods occurring in April, July, and September. Visitors can explore the nearby national state park and various natural parks, which offer breathtaking views and a chance to connect with nature. Whether you're hiking, birdwatching, or simply soaking in the beautiful landscapes, Concepción promises a memorable experience for those looking to escape into the great outdoors.
  • Uguay: Just 27.4km from Mesopotamia, Uguay is a quaint village that offers a peaceful retreat amidst nature. Known for its seasonal influx of tourists, Uguay sees the most visitors during January, March, and November. The village is close to stunning natural parks, making it ideal for those who appreciate serene surroundings and outdoor adventures. With fewer crowds in February and May, Uguay provides a tranquil experience for visitors seeking a slower pace and a chance to connect with the natural beauty of the region.

Things to do in Mesopotamia

In Mesopotamia, Argentina, visitors can enjoy an array of activities including birdwatching, hiking, and wildlife exploration. For a leisurely outdoor experience, consider a night trip to appreciate the area's natural beauty. Additionally, seafront activities provide a perfect backdrop for relaxation, complemented by beach chairs for comfort. Don't miss the local shopping centre for a taste of the region's unique offerings, making your vacation both enjoyable and memorable.

Shopping

Near the vibrant city centre, you can explore the Plaza Shopping for a variety of local crafts and gifts. For a unique experience, visit the Mercado Municipal de Posadas, where you’ll find artisanal products and traditional souvenirs that capture the essence of Mesopotamia.

Recreation

Mesopotamia offers a tranquil wellness retreat at the Eco-Spa, where you can indulge in rejuvenating treatments surrounded by nature. Participate in yoga sessions by the river and enjoy organic meals made from local produce, creating a holistic experience that harmonizes body and mind.

Adventure

In Mesopotamia, explore the Ibera Wetlands for thrilling wildlife spotting and breathtaking landscapes. Experience kayaking on the Paraná River, surrounded by lush jungles, or hike the trails of the Quebrada de Los Cuervos for stunning views and diverse flora and fauna.

Nightlife

Experience the vibrant nightlife in Mesopotamia with a lively evening at La Cueva, known for its local music and dance. For a more relaxed vibe, visit the cozy Café del Río, perfect for enjoying a drink while soaking in the charming atmosphere of the riverside.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mesopotamia

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mesopotamia are October, where the prices are slightly lower. This is in comparison to February and July to August, where prices are slightly higher.
  • The best time to book a hotel: The cheapest time to book a hotel around Mesopotamia is usually 1 month out from when you are planning to stay. If you're a little more spontaneous, you could also peruse Expedia's last minute deals which could secure you a cheaper stay. Look out for the green banner below the price to spot the deals.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mesopotamia is Tuesday. The most expensive day to stay around Mesopotamia is Monday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels that are currently available. To find the best deals and lowest prices, arrange the price filter from low to high.
  • Consider bundling your trip: You can save money by combining your hotel reservation in Mesopotamia with your flights and activities through an Expedia package.

Find the best attractions near Mesopotamia

In Mesopotamia, Argentina, visitors can immerse themselves in breathtaking scenery and adventure by exploring national parks and outdoor attractions. Must-see sites include the picturesque ocean views, the historical Orologopoulos Mansion, and stunning landmarks in the Southern Alps and Rangitata Gorge. Whether you're seeking a peaceful retreat or an exhilarating experience, Mesopotamia offers a blend of nature and history perfect for any traveller.

  • Portal Carambola: A stunning national park 22.5km from Mesopotamia, offering breathtaking scenery and exhilarating outdoor adventures. Perfect for nature lovers seeking a mix of tranquility and excitement in a picturesque setting.

Best time to go to Mesopotamia

The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and June. June is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January80.1°F (26.7°C)Light RainSunnyHighAverage
February77.7°F (25.4°C)Light RainMostly SunnyAverageSlightly High
March72.9°F (22.7°C)Light RainMostly SunnyHighAverage
April66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
May59.5°F (15.3°C)Light RainMostly Sunny
June60.1°F (15.6°C)Light RainMostly Sunny
July53.4°F (11.9°C)Light RainMostly SunnyLowSlightly High
August63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
September60.6°F (15.9°C)Light RainMostly SunnyAverageAverage
October65.8°F (18.8°C)Light RainMostly SunnyAverageSlightly Low
November72.3°F (22.4°C)Light RainSunnyHighAverage
December77.0°F (25.0°C)Light RainSunnyAverageAverage

The nearest major airports for your trip to Mesopotamia

To reach Mesopotamia, Argentina, you can fly into three major airports. ASUncion (ASU-Silvio Pettirossi Intl.) is 376.6km away, with nearby hotels like Factoria Hotel and Gran Bourbon Hotel Asunción offering convenient transportation services. Posadas (PSS-Libertador General Jose de San Martin), located 222.1km away, features options such as La Mision Posadas Hotel, providing airport transportation for guests. Lastly, Resistencia (RES-Resistencia Intl.) is 181.9km from Mesopotamia, with accommodations like Amérian Hotel Casino Gala, facilitating easy access to the airport. These options ensure a smooth journey as you explore the beauty of Mesopotamia.