A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.

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Our top choices for Melrose hotels

A swimming pool with a metal ladder, surrounded by a white fence and green chairs.
A hotel room with a bed, a sofa, a coffee table, and a small table with a lamp.
A hotel room with a patterned carpet, a sofa, a small table, a lamp, and a door with a notice.
A living room with a curved sofa, a wooden cabinet, and a fish tank.

1. Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
Waldo
United States
Ana Laura
CA $137
CA $154 total
includes taxes & fees
Sep 6 - Sep 7
Best Western Waldo Inn and Suites
A room with two beds, a TV, and a door.
A covered corridor with a row of parked cars on one side and a building with blue trim on the other.
A hotel room with a bed, a TV mounted on the wall, a remote control on a table, and a door leading to another room.
A bathroom with a toilet, sink, and mirror.

2. Soho Inn Waldo

Soho Inn Waldo
Waldo
United States
Brandie
CA $73
CA $83 total
includes taxes & fees
Sep 7 - Sep 8
Soho Inn Waldo
A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.
A modern reception desk area with a blue geometric wall design, wooden accents, and a visible reception counter.
An outdoor patio with tables and chairs, a stone wall, and a view of a street with trees and buildings.
A hotel room with two beds, a TV, a desk, and a chair.

3. Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
Starke
United States
John
CA $143
CA $158 total
includes taxes & fees
Oct 4 - Oct 5
Holiday Inn Express Starke by IHG
A clear blue swimming pool with a metal safety fence, surrounded by a building with multiple windows and balconies.
A single-story motel with a red roof and beige walls. It features a covered front porch and a small parking area.
A hotel room with a wooden headboard, a colorful striped bedspread, two bedside lamps, a framed picture on the wall, and a small bedside table with a phone.
A hotel room with two beds, each with a patterned bedspread. There are two wall-mounted lamps on the nightstand between the beds.

4. Red Carpet Inn

Red Carpet Inn
Starke
United States
Omar
CA $96
CA $106 total
includes taxes & fees
Sep 6 - Sep 7
Red Carpet Inn
A hotel lobby with a wooden floor, a chandelier, a ceiling fan, a reception desk, and a wall-mounted information board.
A motel with a large sign reading "Gator Town" and a parking lot in front.
A spacious hallway with wooden flooring, a chandelier, and large windows offering views of the outside.
A hotel room with a flat-screen TV, a refrigerator, a microwave, and a wooden dresser.

5. Gator Town Inn

Gator Town Inn
Gainesville
United States
Katherine
CA $82
CA $92 total
includes taxes & fees
Sep 28 - Sep 29
Gator Town Inn
A swimming pool with a white fence, palm trees, and a building with balconies in the background.
A hotel room with two beds, orange walls, a window with curtains, and a door with a lock.
A hotel reception area with a modern design, featuring a reception desk, a coffee station, and a view of the outdoors.
A small indoor seating area with a vending machine stocked with snacks and drinks, and a glass door entrance.

6. Motel 6 Starke, FL

Motel 6 Starke, FL
Starke
United States
Cedric
CA $87
CA $97 total
includes taxes & fees
Sep 10 - Sep 11
Motel 6 Starke, FL
A hotel room with a bed, bedside lamps, a nightstand, a mirror, a bathroom with a sink and a bathtub.
A bathroom with a bathtub, a sink, and a mirror.
A motel with a sign for 'America's Best Value by Vantage Inn'.
A rectangular pool with a depth of 3 feet 2 inches, surrounded by a white fence and a building with a red roof in the background.

7. Americas Best Value Inn Starke

Americas Best Value Inn Starke
Starke
United States
Jeanette
CA $104
CA $115 total
includes taxes & fees
Sep 6 - Sep 7
Americas Best Value Inn Starke
A hotel room with a large bed, a nightstand, a chair, a window with a view of greenery, and a beach-themed wall mural.
A Days Inn by Wyndham sign with a sunburst logo, a blue arch, and a clear sky.
A modern bathroom with a large mirror, a sink, and a hairdryer.
A Days Inn by Wyndham hotel with a blue awning, large windows, and a parking lot.

8. Days Inn by Wyndham Gainesville Hospital/University Area

Days Inn by Wyndham Gainesville Hospital/University Area
Gainesville
United States
Christy
CA $90
CA $101 total
includes taxes & fees
Sep 6 - Sep 7
Days Inn by Wyndham Gainesville Hospital/University Area
A kitchen with a sink, a microwave, and cabinets.
A room with a patterned sofa, a green door with a decorative glass panel, and a framed picture on the wall.
A small building with a yellow door, surrounded by trees and parked cars.
A compact kitchen with a green countertop, a patterned sofa, and a wall-mounted light fixture.

9. The Humming Bird Suite - Affordable Lakefront Fun

The Humming Bird Suite - Affordable Lakefront Fun
Keystone Heights
CA $111
CA $170 total
includes taxes & fees
Sep 6 - Sep 7
The Humming Bird Suite - Affordable Lakefront Fun
A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.
A fire pit area surrounded by stone tiles, with a metal fence in the background.
A modern hotel lobby with a long dining table, multiple seating areas, and a large window with curtains.
A modern hotel lobby with a reception desk, seating area with chairs and ottomans, a large artwork, and a corridor leading to other rooms.

10. Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
Gainesville
United States
Gladys
CA $118
CA $132 total
includes taxes & fees
Oct 4 - Oct 5
Comfort Suites Gainesville near University
A gazebo with a tiled roof, surrounded by stone pillars and palm trees.
A modern hotel room with a large bed, bedside tables, a desk, and a mirror.
A modern restaurant with a blue wave-patterned wall, a self-service beverage station, and a variety of food items displayed.
A reception area with a modern design, featuring a reception desk, a blue patterned wall, and a glass door leading outside.

11. Best Western Starke

Best Western Starke
Starke
United States
Christopher
CA $134
CA $149 total
includes taxes & fees
Sep 6 - Sep 7
Best Western Starke
A modern kitchen with dark cabinets, stainless steel appliances, and a wooden ceiling.
A porch with two Adirondack chairs, a wooden door, and a sign reading "Downtown Studio Depot Village".
A staircase with dark wooden steps leading to a landing with a small table and chair.
A bathroom with a white vanity, a round mirror, and a black faucet.

12. Depot Village

Depot Village
Gainesville
United States
Trisha
CA $80
CA $183 total
includes taxes & fees
Oct 4 - Oct 5
Depot Village
A hotel lobby with a seating area, a sofa, a table, and a lamp.
A snack and treat display area with refrigerated sections and shelves stocked with various snacks.
A hotel lobby with a reception desk, seating area, and a large wall advertisement.
A multi-story hotel with a brick facade, a prominent signage for Hampton Inn & Suites, and a parking area with several cars.

13. Hampton Inn & Suites Gainesville-Downtown

Hampton Inn & Suites Gainesville-Downtown
Downtown Gainesville
United States
Graziella
CA $127
CA $143 total
includes taxes & fees
Sep 10 - Sep 11
Hampton Inn & Suites Gainesville-Downtown
A modern interior with a staircase, a seating area, and a colorful abstract wall design.
A rooftop pool area with lounge chairs, a small table, and a fire pit.
A spacious lobby with modern furniture, large windows, and a colorful abstract wall.
A modern bar area with a marble countertop, bar stools, and pendant lighting.

14. Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
Downtown Gainesville
United States
maria
CA $138
CA $155 total
includes taxes & fees
Sep 27 - Sep 28
Hyatt Place Gainesville Downtown
A spacious hotel lobby with a curved sofa, a patterned carpet, and a large window with sheer curtains.
A Hilton hotel with a brick facade, multiple windows, and a well-lit entrance.
A large banquet hall with round tables, chairs, and floral centerpieces.
A hotel lobby with a blue patterned carpet, black round tables with candles, beige sofas, and a curved seating area.

15. Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville
Gainesville
United States
Patricia
CA $135
CA $152 total
includes taxes & fees
Sep 10 - Sep 11
Hilton University of Florida Conference Center Gainesville
A modern living room with a sofa, coffee table, and TV. There is a desk with a computer and a chair. The room has wooden flooring and a patterned rug.
A reception desk with a glass partition, a clock, and a sign for 'Quality by Choice Hotels'.
A restaurant with multiple tables and chairs, a kitchen area with appliances, and a flat-screen TV mounted on the wall.
A rectangular swimming pool with a white deck, surrounded by lounge chairs and umbrellas.

16. Quality Inn Gainesville I-75

Quality Inn Gainesville I-75
Gainesville
United States
Shashi
CA $94
CA $105 total
includes taxes & fees
Sep 27 - Sep 28
Quality Inn Gainesville I-75
A multi-story hotel with a central entrance, palm trees, and a clear sky.
A hotel room with a wooden floor, a red armchair, a beige sofa, a TV, and framed artwork on the wall.
A modern living room with a green sofa, a round coffee table, and a fireplace.
A hotel room with a bed, a desk, a television, a sofa, and artwork on the wall.

17. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
Gainesville
United States
Henry
CA $120
CA $135 total
includes taxes & fees
Sep 13 - Sep 14
Country Inn & Suites by Radisson, Gainesville, FL
A wooden dock with a chair, surrounded by trees and a calm water body.
A bedroom with two beds, a nightstand with a lamp, and a window with blinds.
A wooden cabin rental area with a guest registration desk, a sign for cabin rentals, and a sign indicating happy hour hours.
A small, single-story building with a blue exterior, a wooden door, and a window.

18. Yearling Restaurant and Cabins

Yearling Restaurant and Cabins
Hawthorne
United States
Riley
CA $192
CA $216 total
includes taxes & fees
Sep 5 - Sep 6
Yearling Restaurant and Cabins
A dining area with a round table, chairs, a chandelier, and a spiral staircase with a view to the outside.
A bathroom with a white sink, a mirror, and a shower area.
A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.
A yellow building with a covered entrance, large windows, and a parking lot.

19. University Inn Gainesville

University Inn Gainesville
Gainesville
United States
Jhonny
CA $80
CA $90 total
includes taxes & fees
Sep 8 - Sep 9
University Inn Gainesville
A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.
A hotel room with two beds, a large headboard, bedside lamps, and a view of the outdoors through sheer curtains.
A hotel lobby with a stone wall, a flat-screen TV, orange upholstered seating, and a lamp.
A hotel room with a large window offering a view of a cityscape, a blue armchair, and a small table with a lamp.

20. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
Gainesville
United States
James
CA $145
CA $164 total
includes taxes & fees
Sep 7 - Sep 8
Drury Inn & Suites Gainesville
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Learn more about Melrose

Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market.

See all hotels in Melrose
A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.
Photo by Matt Mateo

Top Melrose Hotel Reviews

Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville

10/10 Excellent
"Had the best experience at Chula’s Steak House!9"
Angel 1-night trip
Posted 8 hours ago
Hilton University of Florida Conference Center Gainesville
Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

10/10 Excellent
"I reserved a handicap accessible room, which was clean, comfortable, and met my needs. Handicap parking was available. Breakfast was hot and fulfilling. Staff were friendly and considerate of our needs."
Alethea 1-night trip
Posted 9 hours ago
Country Inn & Suites by Radisson, Gainesville, FL
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

10/10 Excellent
"Very accommodating staff. We got there before check in and they gave us a different room without question. They had popcorn and cookies available for free too which was great! The breakfast was alright. Small selection but didnt expect much given the small scale of the hotel. The shower had some hair in it that wasnt ours... but overall a decent stay"
Rosie 1-night trip
Posted 11 hours ago
Sleep Inn & Suites University/Shands
Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville

10/10 Excellent
"The room was clean. Pool and hot tub were clean and nice temps. The breakfast was good and the evening food and drinks were nice!!"
Tamra 2-night trip
Posted 14 hours ago
Drury Inn & Suites Gainesville
DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

10/10 Excellent
"We had a great stay! The customer service was excellent, the hotel was very clean, and the beds were comfortable. The amenities provided everything we needed for a pleasant and convenient stay. Overall, a very good experience, and we would definitely stay here again!"
Wanda 1-night trip
Posted 20 hours ago
DoubleTree by Hilton Gainesville
Days Inn by Wyndham Gainesville Hospital/University Area

Days Inn by Wyndham Gainesville Hospital/University Area

10/10 Excellent
"Clean room and amazing staff!"
Christy 1-night trip
Posted 2 days ago
Days Inn by Wyndham Gainesville Hospital/University Area
3 Bedroom House on Private Scenic Lake Mable

3 Bedroom House on Private Scenic Lake Mable

10/10 Excellent
"Very cozy, peaceful, laid back. It was just what we needed that weekend since we where dropping our son of at UF."
Heriberto 2-night trip
Posted 3 days ago
3 Bedroom House on Private Scenic Lake Mable
Hampton Inn & Suites Gainesville-Downtown

Hampton Inn & Suites Gainesville-Downtown

10/10 Excellent
"Nice hotel, loved the location"
Graziella 2-night trip
Posted 4 days ago
Hampton Inn & Suites Gainesville-Downtown
Lakefront Nature Escape! Cabin in Keystone Heights

Lakefront Nature Escape! Cabin in Keystone Heights

10/10 Excellent
"We enjoyed our time at this property. The lake was calm and uncrowded. The home was just the right size for our party of 6. The oven is a little small but did what we needed done. If you are planning on using the on-property boat ramp know that it is steep and when we were there the lake was a little low and the ramp ran out before our trailer. Overall, we would stay here again and have already stayed 2 other times."
Jon E. 3-night trip
Posted 2 months ago
Lakefront Nature Escape! Cabin in Keystone Heights

More cheap stays in Melrose

Days Inn by Wyndham Gainesville Hospital/University Area

Days Inn by Wyndham Gainesville Hospital/University Area

2649 Sw 13th St Gainesville FL
CA $90
CA $101 total
Sep 6 - Sep 7
includes taxes & fees
7.6/10 Good! (293 reviews)
Days Inn by Wyndham Gainesville Hospital/University Area
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL
CA $111
CA $125 total
Sep 6 - Sep 7
includes taxes & fees
HOM Hotel Gainesville, SureStay Collection by Best Western
Comfort Inn Gainesville - University Area

Comfort Inn Gainesville - University Area

3440 SW 40th Blvd Gainesville FL
CA $106
CA $127 total
Oct 4 - Oct 5
includes taxes & fees
Comfort Inn Gainesville - University Area
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL
CA $108
CA $130 total
Sep 30 - Oct 1
includes taxes & fees
8.8/10 Excellent! (1,294 reviews)
Sleep Inn & Suites University/Shands
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL
CA $118
CA $132 total
Oct 4 - Oct 5
includes taxes & fees
Comfort Suites Gainesville near University
Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG

15111 S.Highway 301 Starke FL
CA $143
CA $158 total
Oct 4 - Oct 5
includes taxes & fees
9.6/10 Exceptional! (607 reviews)
Holiday Inn Express Starke by IHG

Hotels in Melrose with star rating

Frequently asked questions

What is the best area to stay in Melrose?
The best area to stay in Melrose is typically around the shores of Lake Melrose, particularly on the northern and western sides.This area provides direct access to the lake, which is the heart of Melrose's recreational activities. Properties here often feature private docks, offering convenience for those who enjoy boating, fishing, or simply relaxing by the water. The main roads like State Road 21 run nearby, providing easy access to local shops and eateries while still maintaining a peaceful, residential feel.Families often find this area ideal due to the focus on outdoor activities. Children can enjoy swimming, kayaking, or paddleboarding directly from their accommodation, and the open spaces around the lake are great for playing. The proximity to nature trails also offers opportunities for family walks and exploring the local wildlife.Couples looking for a peaceful retreat will appreciate the quiet surroundings and scenic views of the lake. Many accommodations in this area offer private settings, great for romantic evenings watching the sunset over the water or enjoying a quiet morning coffee on a lakeside porch.
When is the best time to go to Melrose?
The best time to go to Melrose, Florida, is during the spring (March to May) and autumn (September to November) months.During these periods, the weather is pleasantly warm with lower humidity, making it ideal for enjoying outdoor activities. Average temperatures range from 20-28°C (68-82°F), great for exploring the natural beauty of the area, like kayaking on Lake Santa Fe or hiking in the nearby state parks. These seasons also avoid the peak summer heat and the higher risk of hurricanes.Couples looking for a peaceful escape will appreciate the quieter atmosphere during these shoulder seasons. You can enjoy strolls through the small town centre, visit local antique shops, or have a relaxed meal at one of the lakeside restaurants without the larger crowds of peak tourist times.Families will find these times suitable for outdoor adventures. The comfortable temperatures mean children can comfortably explore the parks and enjoy water activities without the intensity of summer heat.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Melrose.
How much is the nightly rate at a Melrose hotel?
Prices for hotels in Melrose often vary, but you can find a great deal from CA $83 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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