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Our top choices for Melrose hotels

Red Carpet Inn

Red Carpet Inn
2.0 star property
Starke
8.6 out of 10, Excellent, (644 reviews)
"Clean, inexpensive with a courteous staff. Will stay there again!"
United States
William
The price is CA $99
CA $109 total
includes taxes & fees
Apr 19 - Apr 20
Red Carpet Inn

Hawthorne Angler's Cabin w/ Lake + Dock Access!

Hawthorne Angler's Cabin w/ Lake + Dock Access!
3.0 star property
Hawthorne
The price is CA $226
CA $480 total
includes taxes & fees
Apr 19 - Apr 20
Hawthorne Angler's Cabin w/ Lake + Dock Access!

Quality Inn & Suites Palatka Riverfront

Quality Inn & Suites Palatka Riverfront
2.5 star property
Palatka
8.2 out of 10, Very good, (1,001 reviews)
"Great room and good breakfast"
United States
Janae
The price is CA $127
CA $141 total
includes taxes & fees
May 5 - May 6
Quality Inn & Suites Palatka Riverfront

Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
Waldo
8.8 out of 10, Excellent, (988 reviews)
"The room was very nice and the staff was excellent "
United States
Brian
The price is CA $140
CA $157 total
includes taxes & fees
May 4 - May 5
Best Western Waldo Inn and Suites

Travelodge by Wyndham Gainesville

Travelodge by Wyndham Gainesville
2.5 star property
Gainesville
7.2 out of 10, Good, (209 reviews)
"We had good staying in this hotel, it is very comfortable and clean."
United States
Alexander
The price is CA $75
CA $85 total
includes taxes & fees
Apr 20 - Apr 21
Travelodge by Wyndham Gainesville

Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
Starke
9.6 out of 10, Exceptional, (526 reviews)
"Facility was very clean and breakfast was very good. Would definitely stay again. "
United States
Sheila
The price is CA $162
CA $179 total
includes taxes & fees
May 10 - May 11
Holiday Inn Express Starke by IHG

Gainesville Lodge

Gainesville Lodge
2.0 star property
Gainesville
8.0 out of 10, Very good, (16 reviews)
"Thank for a great stay. So much better than the usual corporate hotels. Staff were very helpful. Room was very nice."
United Kingdom
Maxwell John
The price is CA $115
CA $129 total
includes taxes & fees
Apr 21 - Apr 22
Gainesville Lodge

Yearling Restaurant and Cabins

Yearling Restaurant and Cabins
2.5 star property
Hawthorne
9.2 out of 10, Wonderful, (207 reviews)
"The Yearling Cabins are somewhat remote. I planned my stay around a guided tour at the Marjorie Kinnan Rawlings State park and dining at the Yearling Restaurant."
United States
Sarah
The price is CA $190
CA $214 total
includes taxes & fees
Apr 20 - Apr 21
Yearling Restaurant and Cabins

Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,179 reviews)
"Breakfast was good , staff was friendly, parking was always available, the room was spacious and clean ."
United States
James
The price is CA $113
CA $135 total
includes taxes & fees
Apr 26 - Apr 27
Sleep Inn & Suites University/Shands

Gator Town Inn

Gator Town Inn
2.0 star property
Gainesville
7.6 out of 10, Good, (864 reviews)
"The room was clean and the beds were comfortable. For the quality price, I would recommend this hotel."
United States
Angela
The price is CA $78
CA $88 total
includes taxes & fees
May 5 - May 6
Gator Town Inn

Hampton Inn Palatka

Hampton Inn Palatka
2.5 star property
Palatka
9.2 out of 10, Wonderful, (656 reviews)
"Courtesy staff, nice room, great view"
United States
Jamie
The price is CA $190
CA $211 total
includes taxes & fees
May 3 - May 4
Hampton Inn Palatka

Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1,308 reviews)
"Was a very clean place. Enjoyed the stay !"
United States
Robert
The price is CA $142
CA $159 total
includes taxes & fees
Apr 26 - Apr 27
Comfort Suites Gainesville near University

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville
2.5 star property
Gainesville
7.4 out of 10, Good, (1,268 reviews)
"Clean room, staf, location and price"
United States
Eduardo R
The price is CA $83
CA $94 total
includes taxes & fees
Apr 20 - Apr 21
Red Roof Inn PLUS+ Gainesville

Best Western Starke

Best Western Starke
2.5 star property
Starke
8.6 out of 10, Excellent, (701 reviews)
"Very pleasant and helpful staff, clean quiet, comfortable room, easy room access to handicapped room from parking. Good proximity to restaurants and shopping."
United States
Marie
The price is CA $146
CA $163 total
includes taxes & fees
Apr 23 - Apr 24
Best Western Starke

Depot Village

Depot Village
2.0 star property
Gainesville
9.6 out of 10, Exceptional, (120 reviews)
"My fav spot to stay in town 💚"
United States
Amanda
The price is CA $46
CA $144 total
includes taxes & fees
Apr 19 - Apr 20
Depot Village

Holiday Inn Express Palatka Northwest by IHG

Holiday Inn Express Palatka Northwest by IHG
2.5 star property
Palatka
9.2 out of 10, Wonderful, (586 reviews)
"Great rooms and friendly staff "
United States
Neil
The price is CA $178
CA $198 total
includes taxes & fees
May 13 - May 14
Holiday Inn Express Palatka Northwest by IHG

Crystal Cove Hotel

Crystal Cove Hotel
2.5 star property
Palatka
7.6 out of 10, Good, (711 reviews)
"Just a nice comfortable spot to stay in nice and quiet all around good place"
United States
Michael
The price is CA $140
CA $156 total
includes taxes & fees
Apr 19 - Apr 20
Crystal Cove Hotel

Sweetwater Branch Inn

Sweetwater Branch Inn
3.5 star property
Gainesville
9.6 out of 10, Exceptional, (1,005 reviews)
"I loved this place! It was a perfect location and charming vibe. The breakfast was amazing."
United States
Jaramee
The price is CA $134
CA $150 total
includes taxes & fees
May 18 - May 19
Sweetwater Branch Inn

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area
2.0 star property
Gainesville
7.6 out of 10, Good, (1,004 reviews)
"Great place all around"
United States
Cadarius
The price is CA $71
CA $80 total
includes taxes & fees
Apr 19 - Apr 20
Super 8 by Wyndham Gainesville I-75 Hospital University Area

Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,431 reviews)
"Great place to stay! Would recommend. "
United States
Michelle
The price is CA $151
CA $169 total
includes taxes & fees
Apr 26 - Apr 27
Drury Inn & Suites Gainesville
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Learn more about Melrose

Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market.

Photo by Matt Mateo
Open Photo by Matt Mateo

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Frequently asked questions

What is the best area to stay in Melrose?
The best area to stay in Melrose is typically around the shores of Lake Melrose, particularly on the northern and western sides.

This area provides direct access to the lake, which is the heart of Melrose's recreational activities. Properties here often feature private docks, offering convenience for those who enjoy boating, fishing, or simply relaxing by the water. The main roads like State Road 21 run nearby, providing easy access to local shops and eateries while still maintaining a peaceful, residential feel.

Families often find this area ideal due to the focus on outdoor activities. Children can enjoy swimming, kayaking, or paddleboarding directly from their accommodation, and the open spaces around the lake are great for playing. The proximity to nature trails also offers opportunities for family walks and exploring the local wildlife.

Couples looking for a peaceful retreat will appreciate the quiet surroundings and scenic views of the lake. Many accommodations in this area offer private settings, great for romantic evenings watching the sunset over the water or enjoying a quiet morning coffee on a lakeside porch.
When is the best time to go to Melrose?
The best time to go to Melrose, Florida, is during the spring (March to May) and autumn (September to November) months.

During these periods, the weather is pleasantly warm with lower humidity, making it ideal for enjoying outdoor activities. Average temperatures range from 20-28°C (68-82°F), great for exploring the natural beauty of the area, like kayaking on Lake Santa Fe or hiking in the nearby state parks. These seasons also avoid the peak summer heat and the higher risk of hurricanes.

Couples looking for a peaceful escape will appreciate the quieter atmosphere during these shoulder seasons. You can enjoy strolls through the small town centre, visit local antique shops, or have a relaxed meal at one of the lakeside restaurants without the larger crowds of peak tourist times.

Families will find these times suitable for outdoor adventures. The comfortable temperatures mean children can comfortably explore the parks and enjoy water activities without the intensity of summer heat.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Melrose.
How can I save on a Melrose hotel booking with Expedia?
Members always get our best prices. Find our best Melrose hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Melrose hotel?
Prices for hotels in Melrose often vary, but you can find a great deal from CA $85 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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