Title: Book The Best Hotels in La Mesa for 2026 from CA $49 - Fully Refundable Options - Expedia.ca [Vacation Rentals in La Mesa](https://expedia.ca/La-Mesa-Vacation-Rentals.d553248635976270713.Travel-Guide-VacationRentals)[La Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesa.d553248635976270713.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.ca/La-Mesa.d553248635976270713.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in La Mesa from CA $49 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 1 - Dec 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976270713&startDate=2025-12-01&endDate=2025-12-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 2 - Dec 3](https://www.expedia.ca/Hotel-Search?regionId=553248635976270713&startDate=2025-12-02&endDate=2025-12-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248635976270713&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976270713&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 27 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Interior](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/1ac93655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/3dba56ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/30ee37bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub, steam room, hot stone massages, facials](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/8ec93765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gran Casa Sayula Hotel & Spa Sayula 9.4/10 Exceptional (124) "Great hotel in Sayula!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph [](https://www.expedia.ca/Sayula-Hotels-Gran-Casa-Sayula-Hotel-Spa.h9600476.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/a046be8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Mexican cuisine ](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/3a5b148c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/971c2e17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/43ffd5a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Casa de los Patios Hotel & Spa Sayula 9.4/10 Exceptional (142) "The hotel is beautiful and staffing is great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tony [](https://www.expedia.ca/Sayula-Hotels-La-Casa-De-Los-Patios-Hotel-Spa.h8055628.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/2e211699.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/997f0592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/eb32d057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/48b4acf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tryp By Wyndham Ciudad Guzman Uttsa Zapotlán el Grande 9.4/10 Exceptional (69) "Excelente hotel" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) armando CA $59 CA $72 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Zapotlan-El-Grande-Hotels-Tryp-By-Wyndham-Ciudad-Guzman-Uttsa.h110349763.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/961d196c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/f4bc1a40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/4766a79c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/5388b611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zapotlan Zapotlán el Grande 8.0/10 Very good (229) "Room was clean, receptionist was not friendly. Hotel was ok for the value" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ivette CA $41 CA $49 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Zapotlan.h101472426.Hotel-Information) ![Loft](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/86962876.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Studio](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/fd0f15fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/2b685435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft | Bathroom](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/13b64b3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lofts Independencia Sayula Sayula 5.4/10 (3) "Not satisfied charges for parking, pool and needed to ask for fresh towels n toilet paper no AC" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ARTURO CA $47 CA $57 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Sayula-Hotels-Lofts-Independencia-Sayula.h114153710.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/37a78592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/502e172b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/edbe39a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Quadruple Room](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/e047e127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capital O Colón, Ciudad Guzmán Jalisco Zapotlán el Grande 6.8/10 (153) "Very nice hotel, nice pool, easy to get to the center and clean" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Alex CA $41 CA $53 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Colon.h48709526.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-15&endDate=2025-12-16®ionId=553248635976270713&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels.d553248635976270713.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels.d553248635976270713.Travel-Guide-Hotels) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=HTG_BF_PROMO_553248635976270713) ## More cheap stays in La Mesa ![Hotel Zapotlan](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/961d196c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Zapotlan Federico del Toro, 61 Zapotlán el Grande JAL CA $41 CA $49 total Dec 2 - Dec 3 includes taxes & fees 7.8/10 Good! (229 reviews) [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Zapotlan.h101472426.Hotel-Information) ![Capital O Colón, Ciudad Guzmán Jalisco](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/37a78592_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Capital O Colón, Ciudad Guzmán Jalisco 655 Avenida Cristobal Colon Zapotlán el Grande JAL CA $41 CA $53 total Dec 2 - Dec 3 includes taxes & fees 6.6/10 (152 reviews) [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Colon.h48709526.Hotel-Information) ![Lofts Independencia Sayula](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/86962876_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Lofts Independencia Sayula 62 Independencia Centro Histórico Sayula Jal. CA $47 CA $57 total Jan 1 - Jan 2, 2026 includes taxes & fees 5.4/10 (3 reviews) [](https://expedia.ca/Sayula-Hotels-Lofts-Independencia-Sayula.h114153710.Hotel-Information) ![Tryp By Wyndham Ciudad Guzman Uttsa](https://images.trvl-media.com/lodging/107000000/106200000/106190600/106190588/c92a1940_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tryp By Wyndham Ciudad Guzman Uttsa Av Jose Maria Gonzalez 552 Col Zapotl Y Fracc Cond Zapotlán el Grande JAL [Get rates](https://expedia.ca/Hotel-Search?startDate=15%2F12%2F2025&endDate=16%2F12%2F2025&selected=106190588&PinnedHotelID=106190588&HadPinnedHotel=true®ionId=553248635976270713) 6/10 (2 reviews) [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Tryp-By-Wyndham-Ciudad-Guzman-Uttsa.h106190588.Hotel-Information) ![Cabanas del Volcan](https://images.trvl-media.com/lodging/40000000/39080000/39070700/39070605/f057915e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Cabanas del Volcan La Yerbabuena km 1 Comala COL [Get rates](https://expedia.ca/Hotel-Search?startDate=15%2F12%2F2025&endDate=16%2F12%2F2025&selected=39070605&PinnedHotelID=39070605&HadPinnedHotel=true®ionId=553248635976270713) [](https://expedia.ca/Colima-Hotels-Cabanas-Del-Volcan.h39070605.Hotel-Information) ![Casa de Campo con Increíble Vista al Volcán de Colima y un Clima Excepcional.!](https://images.trvl-media.com/lodging/109000000/108420000/108411100/108411042/298a5be6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa de Campo con Increíble Vista al Volcán de Colima y un Clima Excepcional.! COFRADIA DE SUCHITLAN, COMALA COL [Get rates](https://expedia.ca/Hotel-Search?startDate=15%2F12%2F2025&endDate=16%2F12%2F2025&selected=108411042&PinnedHotelID=108411042&HadPinnedHotel=true®ionId=553248635976270713) [](https://expedia.ca/Villa-De-Alvarez-Hotels-Casa-De-Campo-Con-Increible-Vista-Al-Volcan-De-Colima-Y-Un-Clima-Excepcional.h108411042.Hotel-Information) ## Recent reviews of La Mesa hotels ![Hotel Zapotlan](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/961d196c_y.jpg) ### Hotel Zapotlan 5/5 Excellent "Rooms are ok" A verified traveller stayed at Hotel Zapotlan Posted 2 days ago [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Zapotlan.h101472426.Hotel-Information) ![Lofts Independencia Sayula](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/86962876_y.jpg) ### Lofts Independencia Sayula 1/5 Terrible "Not satisfied charges for parking, pool and needed to ask for fresh towels n toilet paper no AC" A verified traveller stayed at Lofts Independencia Sayula Posted 6 days ago [](https://expedia.ca/Sayula-Hotels-Lofts-Independencia-Sayula.h114153710.Hotel-Information) ![La Casa de los Patios Hotel & Spa](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/a046be8e_y.jpg) ### La Casa de los Patios Hotel & Spa 5/5 Excellent "Good place" A verified traveller stayed at La Casa de los Patios Hotel & Spa Posted 2 weeks ago [](https://expedia.ca/Sayula-Hotels-La-Casa-De-Los-Patios-Hotel-Spa.h8055628.Hotel-Information) ![Capital O Colón, Ciudad Guzmán Jalisco](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/37a78592_y.jpg) ### Capital O Colón, Ciudad Guzmán Jalisco 5/5 Excellent "Estancia buena " A verified traveller stayed at Capital O Colón, Ciudad Guzmán Jalisco Posted 1 month ago [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Colon.h48709526.Hotel-Information) ![Tryp By Wyndham Ciudad Guzman Uttsa](https://images.trvl-media.com/lodging/107000000/106200000/106190600/106190588/c92a1940_y.jpg) ### Tryp By Wyndham Ciudad Guzman Uttsa 4/5 Good "Stayed for two nights during the Fiestas. Super close to the Féria. However a bit far from the center. Staff was very helpful and room comfortable and clean. Good place to stay if you don’t mind taking a cab into town or driving in and you want some quiet." A verified traveller stayed at Tryp By Wyndham Ciudad Guzman Uttsa Posted 2 months ago [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Tryp-By-Wyndham-Ciudad-Guzman-Uttsa.h106190588.Hotel-Information) ![Tryp By Wyndham Ciudad Guzman Uttsa](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/2e211699_y.jpg) ### Tryp By Wyndham Ciudad Guzman Uttsa 5/5 Excellent "Very beautiful hotel! Super clean! Breakfast was good as well! Very friendly staff!" A verified traveller stayed at Tryp By Wyndham Ciudad Guzman Uttsa Posted 3 months ago [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Tryp-By-Wyndham-Ciudad-Guzman-Uttsa.h110349763.Hotel-Information) ![Gran Casa Sayula Hotel & Spa](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/1ac93655_y.jpg) ### Gran Casa Sayula Hotel & Spa 5/5 Excellent "Great hotel in Sayula!!" A verified traveller stayed at Gran Casa Sayula Hotel & Spa Posted 3 months ago [](https://expedia.ca/Sayula-Hotels-Gran-Casa-Sayula-Hotel-Spa.h9600476.Hotel-Information) ## Frequently asked questions ### Where can I find the best nightlife in La Mesa? > La Mesa is a charming neighbourhood in Jalisco, Mexico, known for its vibrant local culture and friendly atmosphere. > > > > While La Mesa itself is more renowned for its family-friendly environment and traditional dining options, you can venture nearby to find some lively nightlife. Areas like Tlaquepaque and Guadalajara, which are just a short drive away, offer a plethora of bars, clubs, and live music venues that cater to diverse tastes. > > > > In Tlaquepaque, you'll find a wonderful mix of artisan shops and vibrant bars, often featuring live mariachi music that adds to the festive atmosphere. Meanwhile, Guadalajara is home to an exciting nightlife scene, with streets like Avenida Chapultepec brimming with trendy bars and clubs where you can dance the night away. ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right La Mesa hotel for you. ### How can I save on a La Mesa hotel booking with Expedia? > Before booking your La Mesa hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a La Mesa hotel? > Prices for hotels in La Mesa often vary, but you can find a great deal from CA $49 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)