Title: Browse the Best Santa Cruz Island Resorts from CA $1,306 | Expedia.ca [Santa Cruz Island Travel Guide](https://expedia.ca/Santa-Cruz-Island.dx6053670)[Hotels in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Vacation-Rentals.d6053670.Travel-Guide-VacationRentals)[Flights to Santa Cruz Island](https://expedia.ca/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)[Things to do in Santa Cruz Island](https://expedia.ca/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)[Santa Cruz Island Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz-Island.d6053670.Car-Rental-Guide)[Santa Cruz Island Vacation Packages](https://expedia.ca/Santa-Cruz-Island.d6053670.Destination-Travel-Guides) ![Galapagos Marine Iguana walking and swimming on Tortuga bay. Marine iguanas on beach on Santa Cruz Island, Galapagos Islands. Animals, wildlife and amazing nature in Ecuador, South America](https://images.trvl-media.com/place/6053670/54bcca80-11e8-424a-9353-2c1a8014c5d5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Resort Hotels in Santa Cruz Island from CA $1,306 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2026-01-02&endDate=2026-01-04&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2026-01-09&endDate=2026-01-11&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2026-01-23&endDate=2026-01-25&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2026-02-20&endDate=2026-02-22&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz Island resorts ![Property grounds](https://images.trvl-media.com/lodging/40000000/39100000/39090500/39090419/eff9a048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/40000000/39100000/39090500/39090419/064ecc89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom](https://images.trvl-media.com/lodging/40000000/39100000/39090500/39090419/065b4fc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/40000000/39100000/39090500/39090419/f72e6b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Jacuzzi Suite On The Bay w/ City, Harbor & Ocean Views (READ AD FIRST) [](https://www.expedia.ca/Puerto-Ayora-Hotels-Luxury-Jacuzzi-Suite-On-The-Bay-W-City.h39090419.Hotel-Information) Puerto Ayora CA $889 CA $1,306 total Dec 27 - Dec 28 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Luxury-Jacuzzi-Suite-On-The-Bay-W-City.h39090419.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-09&endDate=2026-01-10®ionId=6053670&adults=2&lodging=HOTEL_RESORT&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Island-Resort-Hotels.d6053670-aaResortHotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Island-Resort-Hotels.d6053670-aaResortHotels.Travel-Guide-Accommodation) ## Top Santa Cruz Island Hotel Reviews ![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/b6171efd_y.jpg) ### Hotel el descanso del Guia 10/10 Excellent "Pool needs a ladder on the deep side" [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information) ![Posada del Mar](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/e7fb3ff1_y.jpg) ### Posada del Mar 10/10 Excellent "Owner is a great host. Free water and helped us with any questions we had. Great central location. Walkable to everything: shops, restaurants, pier/dock " [](https://expedia.ca/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information) ![Hotel Fiesta](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/b440b32f_y.jpg) ### Hotel Fiesta 10/10 Excellent "Staff was efficient room was clean " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information) ![Blu Galapagos Sustainable Waterfront Lodge](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e_y.jpg) ### Blu Galapagos Sustainable Waterfront Lodge 10/10 Excellent "Beautiful property " [](https://expedia.ca/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Capitan Max B&B](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48_y.jpg) ### Capitan Max B&B 10/10 Excellent "A great property within walking distance from all the restaurants etc. They have a basic breakfast which does the job. The staff were very friendly and accomodating. They even allowed us to get into the room very early after our ferry arriving into Santa Cruz. " [](https://expedia.ca/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![El Barranco Galapagos](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/910f927d_y.jpg) ### El Barranco Galapagos 10/10 Excellent "Incredible place to book your stay in Santa Cruz. Excelent service, rooms and personel. " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information) ![Maidith Galapagos Inn](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/1dd0538f_y.jpg) ### Maidith Galapagos Inn 10/10 Excellent "This was a great stay! The hotel is so cute and the staff is top notch! The rooms were spacious, had plenty of shelving, and the bed was comfortable. The hotel is convenient, located near stores, Darwin Ave, restaurants, and bars. It is about a 10 minute walk to the pier, but they will coordinate taxis if you need it. They give you a discount to a local tour agency and restaurant. The staff is very helpful and accommodating. I skipped breakfast and told them I was going to Isabela Island and they made a to-go bag for lunch for me. Highly recommend this place!" [](https://expedia.ca/Puerto-Ayora-Hotels-Maidith-Galapagos-Inn.h88474681.Hotel-Information) ![Hotel Palace Galapagos](https://images.trvl-media.com/lodging/12000000/11060000/11050700/11050675/48760e17_y.jpg) ### Hotel Palace Galapagos 10/10 Excellent "Absolutely happy with everything!!!! My room was cleaned before I back from my day out!!! Great service! Recommend to everyone!!! Close to everything !! Loved it " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Palace-Galapagos.h11050675.Hotel-Information) ![Hotel Cucuve](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/733c9cb5_y.jpg) ### Hotel Cucuve 10/10 Excellent "Best place we stayed at in Ecuador. Clean, friendly and affordable. " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) ## Find out more about Santa Cruz Island ## Santa Cruz Island Resorts information | Number of reviews | | | ----------------- | --------- | | Accommodation | 1 Resorts | | Lowest Price | CA $1,306 | | Highest Price | CA $1,306 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Santa Fe Island ](https://www.expedia.ca/5Star-Santa-Fe-Island-Hotels.s50-0-d6336630.Travel-Guide-Filter-Hotels) - [Baltra Hotels ](https://www.expedia.ca/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Aparthotels in Bartolome Island ](https://www.expedia.ca/Bartolome-Island-Apart-Hotels.d6336382-aaApartHotels.Travel-Guide-Accommodation) - [Lgbt Friendly Hotels in Bellavista ](https://www.expedia.ca/Bellavista-Hotels-LGBT-Friendly-Hotel.0-0-d6342722-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Bellavista Hotels ](https://www.expedia.ca/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - 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