South Main
Houston
Visit South Main
Things to do
Houston: Space Center Houston Admission Ticket
CA $42
per adult
92% of travellers recommend
Houston's Official City & Mural Tour!
CA $56
per adult
88% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
CA $17
per adult
74% of travellers recommend
Houston: Cistern Art Installation "Undercurrents"
CA $21
per adult
Houston Buffalo Bayou Park Cistern History Tour
CA $21
per adult
Viral Drip Bear Painting w/ RnB & Hip Hop Tunes
CA $64
per adult
South Main Hotel Deals
Wyndham Houston at Reliant Park & Medical Center
8686 Kirby Drive Houston TX
The price is CA $138 per night from Nov 9 to Nov 10
CA $138
CA $162 total
Nov 9 - Nov 10
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and onsite spa services. Our guests praise the helpful staff ...
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
5353 Westheimer Rd Houston TX
The price is CA $159 per night from Nov 24 to Nov 25
CA $159
CA $187 total
Nov 24 - Nov 25
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
Club Quarters Hotel Downtown, Houston
1085 Rusk Street Houston TX
The price is CA $126 per night from Nov 19 to Nov 20
CA $126
CA $148 total
Nov 19 - Nov 20
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,580 reviews)
"Every day fixing bed and cleaning r"
Reviewed on Nov 6, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
The price is CA $116 per night from Nov 22 to Nov 23
CA $116
CA $138 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
The Whitehall Houston
1700 Smith St Houston TX
The price is CA $175 per night from Dec 6 to Dec 7
CA $175
CA $205 total
Dec 6 - Dec 7
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,499 reviews)
"Location"
Reviewed on Nov 5, 2026
The Royal Sonesta Houston Galleria
2222 West Loop South Houston TX
The price is CA $180 per night from Nov 22 to Nov 23
CA $180
CA $211 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Main
Find the best South Main areas and neighborhoods for the activities you enjoy most.
Downtown Houston
Known for its abundant dining options and live music, there's plenty to explore in Downtown Houston. Top attractions like Daikin Park and Toyota Center are major draws, and you can catch the metro at Central Station Main or Main Street Square Station to see more of the city.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.
Texas Medical Center
Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
