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Our top choices for South Central Houston hotels

1. Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterSouth Central Houston
8.6 out of 10, Excellent, (2,237 reviews)
The price is CA $116
CA $138 total
includes taxes & fees
Nov 22 - Nov 23

2. Downtowner Inns - Houston Downtown
Downtowner Inns - Houston DowntownSouth Central Houston
9.2 out of 10, Wonderful, (275 reviews)
The price is CA $125
CA $146 total
includes taxes & fees
Nov 11 - Nov 12

3. Americas Best Value Inn Medical Center Downtown
Americas Best Value Inn Medical Center DowntownSouth Central Houston
8.0 out of 10, Very good, (1,004 reviews)
The price is CA $122
CA $143 total
includes taxes & fees
Nov 6 - Nov 7

4. InterContinental Houston by IHG
InterContinental Houston by IHGSouth Central Houston
9.4 out of 10, Exceptional, (1,007 reviews)
The price is CA $212
CA $276 total
includes taxes & fees
Nov 22 - Nov 23

5. DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston
8.4 out of 10, Very good, (720 reviews)
The price is CA $159
CA $186 total
includes taxes & fees
Nov 22 - Nov 23

6. The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,278 reviews)
The price is CA $203
CA $252 total
includes taxes & fees
Nov 15 - Nov 16

7. Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum DistrictSouth Central Houston
9.0 out of 10, Wonderful, (1,001 reviews)
The price is CA $213
CA $294 total
includes taxes & fees
Nov 22 - Nov 23

8. Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,004 reviews)
The price is CA $270
CA $382 total
includes taxes & fees
Nov 22 - Nov 23

9. Sentral Forme Houston
Sentral Forme HoustonSouth Central Houston
9.2 out of 10, Wonderful, (98 reviews)
The price is CA $231
CA $311 total
includes taxes & fees
Nov 16 - Nov 17

10. 2824 Aeon Living
2824 Aeon LivingSouth Central Houston
The price is CA $174
CA $204 total
includes taxes & fees
Nov 8 - Nov 9

11. Hilton University of Houston
Hilton University of HoustonSouth Central Houston
9.0 out of 10, Wonderful, (993 reviews)
The price is CA $205
CA $240 total
includes taxes & fees
Nov 23 - Nov 24

12. La Maison in Midtown an urban B&B
La Maison in Midtown an urban B&BSouth Central Houston
9.8 out of 10, Exceptional, (608 reviews)
The price is CA $235
CA $275 total
includes taxes & fees
Nov 9 - Nov 10

13. Wanderstay Boutique Hotel
Wanderstay Boutique HotelSouth Central Houston
9.8 out of 10, Exceptional, (83 reviews)
The price is CA $183
CA $214 total
includes taxes & fees
Dec 1 - Dec 2

14. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults OnlySouth Central Houston
9.6 out of 10, Exceptional, (221 reviews)
The price is CA $289
CA $359 total
includes taxes & fees
Nov 16 - Nov 17

15. Fifa Stay 2BR Near NRG DT Med Center -2
Fifa Stay 2BR Near NRG DT Med Center -2South Central Houston
The price is CA $201
CA $235 total
includes taxes & fees
Nov 8 - Nov 9

16. Scott Inn Suites - Downtown Houston
Scott Inn Suites - Downtown HoustonSouth Central Houston
8.4 out of 10, Very good, (48 reviews)
The price is CA $90
CA $105 total
includes taxes & fees
Dec 6 - Dec 7

17. Southmore Boulevard Motel
Southmore Boulevard MotelSouth Central Houston
5.8 out of 10, (245 reviews)
The price is CA $82
CA $96 total
includes taxes & fees
Nov 16 - Nov 17

18. Extended Stay America Suites Houston Med Ctr Braeswood Bl
Extended Stay America Suites Houston Med Ctr Braeswood BlSouth Central Houston
6.2 out of 10, (1,009 reviews)
The price is CA $95
CA $111 total
includes taxes & fees
Dec 6 - Dec 7

19. Wanderstay Houston Hostel
Wanderstay Houston HostelSouth Central Houston
8.2 out of 10, Very good, (219 reviews)
The price is CA $96
CA $113 total
includes taxes & fees
Nov 8 - Nov 9

20. Houston Lux Townhome
Houston Lux TownhomeSouth Central Houston
9.8 out of 10, Exceptional, (9 reviews)
The price is CA $301
CA $352 total
includes taxes & fees
Dec 1 - Dec 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare top hotels in South Central Houston
![]() Hilton Houston Plaza/Medical CenterSouth Central Houston | ![]() Downtowner Inns - Houston DowntownSouth Central Houston | ![]() Americas Best Value Inn Medical Center DowntownSouth Central Houston | ![]() InterContinental Houston by IHGSouth Central Houston | ![]() DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston |
|---|---|---|---|---|
8.6 Excellent 2,237 reviews | 9.2 Wonderful 275 reviews | 8.0 Very good 1,004 reviews | 9.4 Exceptional 1,007 reviews | 8.4 Very good 720 reviews |
The price is CA $116 CA $138 total includes taxes & fees Nov 22 - Nov 23 | The price is CA $125 CA $146 total includes taxes & fees Nov 11 - Nov 12 | The price is CA $122 CA $143 total includes taxes & fees Nov 6 - Nov 7 | The price is CA $212 CA $276 total includes taxes & fees Nov 22 - Nov 23 | The price is CA $159 CA $186 total includes taxes & fees Nov 22 - Nov 23 |
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Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston

Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.











































































































