Title: Book The Best Hotels in Greencastle, MO for 2025 from CA $90 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Greencastle](https://expedia.ca/Greencastle-Vacation-Rentals.d553248634983462000.Travel-Guide-VacationRentals)[Greencastle Car Rentals](https://expedia.ca/Car-Rentals-In-Greencastle.d553248634983462000.Car-Rental-Guide)[Greencastle Vacation Packages](https://expedia.ca/Greencastle.d553248634983462000.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Greencastle, MO from CA $90 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Greencastle Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Greencastle%2C+Missouri%2C+United+States+of+America®ionId=553248634983462000&latLong=40.262523%2C-92.877981&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=PETS) ## Check prices for these dates Tonight [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=553248634983462000&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248634983462000&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248634983462000&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248634983462000&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 40 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/093bb3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/59d144bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/f3c5f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Kirksville Kirksville 6.8/10 (1006) "My wife got food poisoning from breakfast we would like a refund " CA $80 CA $90 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/0cfe6b5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/a6904e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/33e2a913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/06554a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Kirksville University Area Kirksville 7.8/10 Good (884) "Love staying here! Just wish the pool was functional, especially in the hot summer months. " CA $89 CA $100 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Refrigerator & Microwave](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/3ced37b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/0822c1df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/ebcfa50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Kirksville Kirksville 9.2/10 Wonderful (537) "Clean hotel with friendly staff. " CA $191 CA $216 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/9c660a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/4afe2a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/d203c711.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Kirksville-University Area Kirksville 9.0/10 Wonderful (101) "Clean room, friendly staff and a good breakfast." CA $91 CA $102 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/781fda5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/26642d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/35d9f717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Kirksville - University Area by IHG Kirksville 9.2/10 Wonderful (490) "They were really nice to us when we chevked inn and when we left only stsyed one night but i would stay there again." CA $177 CA $201 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/2dd82658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/86a6efae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/74b6e2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/45e37c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Kirksville Kirksville 7.6/10 Good (386) "Good place " CA $87 CA $113 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/fa987a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/9b5928a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/9afc2091.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/b5263971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Knights Inn Kirksville Kirksville 7.2/10 Good (247) "It was ok" CA $95 CA $107 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11®ionId=553248634983462000&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGreencastle-Hotels.d553248634983462000.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGreencastle-Hotels.d553248634983462000.Travel-Guide-Hotels) ## More cheap stays in Greencastle ![Baymont by Wyndham Kirksville University Area](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/0cfe6b5f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Kirksville University Area 2702 South Franklin, Kirksville, MO CA $89 CA $100 total Oct 19 - Oct 20 includes taxes & fees 7.6/10 Good! (884 reviews) [](https://expedia.ca/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information) ![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Kirksville-University Area 1101 Country Club Dr, Kirksville, MO CA $91 CA $102 total Sep 28 - Sep 29 includes taxes & fees 8.8/10 Excellent! (98 reviews) [](https://expedia.ca/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Kirksville 2604 N. Baltimore Street, Kirksville, MO CA $191 CA $216 total Oct 2 - Oct 3 includes taxes & fees 9/10 Wonderful! (537 reviews) [](https://expedia.ca/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Kirksville - University Area by IHG 2523 South Franklin St., Kirksville, MO CA $177 CA $201 total Sep 28 - Sep 29 includes taxes & fees 9.2/10 Wonderful! (490 reviews) [](https://expedia.ca/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Quality Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/2dd82658_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Kirksville 2209 N Baltimore St, Kirksville, MO CA $87 CA $113 total Sep 28 - Sep 29 includes taxes & fees 7.4/10 Good! (386 reviews) [](https://expedia.ca/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information) ![Days Inn by Wyndham Kirksville](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Kirksville 3805 S Baltimore St, Kirksville, MO CA $80 CA $90 total Sep 28 - Sep 29 includes taxes & fees 6.6/10 (1,005 reviews) [](https://expedia.ca/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) ## Hotels in Greencastle with star-rating ![2 Star Hotels](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/0cfe6b5f_w.jpg) 2 Star Hotels 10 properties [](https://expedia.ca/2Star-Greencastle-Hotels.s20-0-d553248634983462000.Travel-Guide-Filter-Hotels) ## Recent reviews of Greencastle hotels ![Hampton Inn Kirksville](//images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302_y.jpg) ### Hampton Inn Kirksville 5/5 Excellent "Clean hotel with friendly staff. " A verified traveller stayed at Hampton Inn Kirksville Posted 4 days ago [](https://expedia.ca/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Super 8 by Wyndham Kirksville-University Area](//images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg) ### Super 8 by Wyndham Kirksville-University Area 5/5 Excellent "They have remodeled this property. Probably the nicest super 8 I know of. Front desk very good. Only drawback is no elevator" A verified traveller stayed at Super 8 by Wyndham Kirksville-University Area Posted 9 days ago [](https://expedia.ca/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![New tiny home in an incredible private setting among all nature has to offer.](//images.trvl-media.com/lodging/118000000/117030000/117029100/117029091/2899d4ac_y.jpg) ### New tiny home in an incredible private setting among all nature has to offer. 5/5 Excellent "Our stay at The Tiny Nest was everything we expected and more. The hosts were so nice and generous, they thought of everything! The tiny home is clean, comfortable and very homey. Highly recommend 10/10 It was so fun to interact with the animals, and sitting out drinking coffee in the mornings ... so relaxing!" A verified traveller stayed at New tiny home in an incredible private setting among all nature has to offer. Posted 11 days ago [](https://expedia.ca/Kirksville-Hotels-New-Tiny-Home-In-An-Incredible-Private-Setting-Among-All-Nature-Has-To-Offer.h117029091.Hotel-Information) ![Holiday Inn Express & Suites Kirksville - University Area by IHG](//images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg) ### Holiday Inn Express & Suites Kirksville - University Area by IHG 5/5 Excellent Amazing Hotel! "The service desk guy was friendly and accommodating. The room was nice, beds slept well. The pool chemical was off or the filter wasn't working properly. but, my grandchildren enjoyed it anyway. The breakfast was very good. It had biscuits & gravy, eggs, sausage, toast, bagels, pancakes, yogurt they dont skip on the items they offer. " A verified traveller stayed at Holiday Inn Express & Suites Kirksville - University Area by IHG Posted 3 weeks ago [](https://expedia.ca/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Home in the Heart of Kirksville](//images.trvl-media.com/lodging/104000000/103100000/103097400/103097370/1c70daa1_y.jpg) ### Home in the Heart of Kirksville 5/5 Excellent "A perfect cute place to stay!! We loved it!! Thank you " A verified traveller from Macon Missourri stayed at Home in the Heart of Kirksville Posted 1 month ago [](https://expedia.ca/Kirksville-Hotels-Home-In-The-Heart-Of-Kirksville.h103097370.Hotel-Information) ![Little Blue Cottage - Charming 1-bedroom cottage in Kirksville](//images.trvl-media.com/lodging/109000000/108400000/108390200/108390143/acd401ea_y.jpg) ### Little Blue Cottage - Charming 1-bedroom cottage in Kirksville 5/5 Excellent "A lot of old homes that are not well taken care of. " A verified traveller stayed at Little Blue Cottage - Charming 1-bedroom cottage in Kirksville Posted 2 months ago [](https://expedia.ca/Kirksville-Hotels-Little-Blue-Cottage-Charming-1-Bedroom-Cottage-In-Kirksville.h108390143.Hotel-Information) ![Days Inn by Wyndham Kirksville](//images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76_y.jpg) ### Days Inn by Wyndham Kirksville 5/5 Excellent "Needs pest control because the hotel has roaches " A verified traveller stayed at Days Inn by Wyndham Kirksville Posted 2 months ago [](https://expedia.ca/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) ![Base Camp Cottage](//images.trvl-media.com/lodging/112000000/111840000/111833600/111833563/aa1f0009_y.jpg) ### Base Camp Cottage 5/5 Excellent "This house was perfect for my family to stay in. Our family was having a reunion in Thousand Hills State Park and this was just a short drive away. I SO appreciated that there were a few little toys for my kids to play with. The house had everything we needed and was very clean. Would definitely recommend! " A verified traveller stayed at Base Camp Cottage Posted 3 months ago [](https://expedia.ca/Kirksville-Hotels-Base-Camp-Cottage.h111833563.Hotel-Information) ![Country Cabin In The Woods](//images.trvl-media.com/lodging/105000000/104310000/104308300/104308277/529c3996_y.jpg) ### Country Cabin In The Woods 5/5 Excellent "The cabin was a great get away from the town. Very remote and peaceful cabin. Very clean. Could have used some brighter lighting. It was difficult to play games at the kitchen table after sunset. Thank you!!!" A verified traveller stayed at Country Cabin In The Woods Posted 3 months ago [](https://expedia.ca/Kirksville-Hotels-Located-10-Minutes-From-Thousand-Hills-And-15-Minutes-From-Kirksville.h104308277.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Greencastle. ### How can I save on a Greencastle hotel booking with Expedia? > Before booking your Greencastle hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Greencastle hotel? > Prices for hotels in Greencastle often vary, but you can find a great deal from CA $90 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Atlanta Hotels](https://www.expedia.ca/Atlanta-Hotels.d553248634983075091.Travel-Guide-Hotels) - [Motels in Atlanta](https://www.expedia.ca/Atlanta-Motels.d553248634983075091-aaMotels.Travel-Guide-Accommodation) - [Vacation Homes in Atlanta](https://www.expedia.ca/Atlanta-Private-Vacation-Homes.d553248634983075091-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cabin Rentals in Brookfield](https://www.expedia.ca/Brookfield-Cabins.d55605-aaCabins.Travel-Guide-Accommodation) - [Pet-Friendly Hotels in Brookfield](https://www.expedia.ca/Brookfield-Hotels-Pet-Friendly-Hotel.0-0-d55605-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Brookfield Hotels](https://www.expedia.ca/Brookfield-Hotels.d55605.Travel-Guide-Hotels) - [Motels in Brookfield](https://www.expedia.ca/Brookfield-Motels.d55605-aaMotels.Travel-Guide-Accommodation) - [Browning Hotels](https://www.expedia.ca/Browning-Hotels.d553248634983413509.Travel-Guide-Hotels) - [Bucklin Hotels](https://www.expedia.ca/Bucklin-Hotels.d553248634983432916.Travel-Guide-Hotels) - [Callao Hotels](https://www.expedia.ca/Callao-Hotels.d3000444667.Travel-Guide-Hotels) - [Putnam County Hotels](https://www.expedia.ca/Destinations-In-Putnam-County.d553248635976432178.Hotel-Destinations) - [B&B in Downing](https://www.expedia.ca/Downing-Bed-And-Breakfast.d3000349344-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Downing Hotels](https://www.expedia.ca/Downing-Hotels.d3000349344.Travel-Guide-Hotels) - [Cheap Hotels in Edina](https://www.expedia.ca/Edina-Hotels-Cheap-Hotels.0-0-d3000444857-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Edina](https://www.expedia.ca/Edina-Hotels-Luxury-Hotel.0-0-d3000444857-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Edina Hotels](https://www.expedia.ca/Edina-Hotels.d3000444857.Travel-Guide-Hotels) - [Apartments in Elmer](https://www.expedia.ca/Elmer-Apartments.d553248634983107048-aaApartments.Travel-Guide-Accommodation) - [Ethel Hotels](https://www.expedia.ca/Ethel-Hotels.d102383.Travel-Guide-Hotels) - [Apartments in Galt](https://www.expedia.ca/Galt-Apartments.d553248634983584331-aaApartments.Travel-Guide-Accommodation) - [Hotels near Gen. 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