Dona Ana Vacation Rentals

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Vacation Rentals in Dona Ana

Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis

2.0 star property
9.0 out of 10, Wonderful, (2)
"Perfect size 3 bedroom, 2 bath for our family of 5. Close to freeway and various stores. Budget friendly was a plus. "
The price is CA $112
CA $249 total
includes taxes & fees
Sep 9 - Sep 10
Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis

Desert Pool Oasis located in the heart of Las Cruces

9.8 out of 10, Exceptional, (121)
"It’s a great location to everything. Quiet neighborhood, everything you need is there . Pool was nice. House was clean , well organized."
Desert Pool Oasis located in the heart of Las Cruces

Elvis’s Cozy Casa- Charming 3 bedroom,2 bathroom home w/ Mountain views

10.0 out of 10, Exceptional, (13)
"The home is in a good area. Had excellent communication with the host. The home is gorgeous and we loved all the amenities and details. So happy we stayed here."
The price is CA $180
CA $285 total
includes taxes & fees
Sep 9 - Sep 10
Elvis’s Cozy Casa- Charming 3 bedroom,2 bathroom home w/ Mountain views

New Casita/Suite No cleaning fee.

10.0 out of 10, Exceptional, (17)
"The property was extremely comfortable and quiet. The amenities were excellent and our hosts were warm and welcoming. "
The price is CA $142
CA $184 total
includes taxes & fees
Sep 14 - Sep 15
New Casita/Suite No cleaning fee.

Cozy pet friendly house with a great outdoor space, and fully stocked kitchen.

10.0 out of 10, Exceptional, (30)
"Jacuzzi was great"
Cozy pet friendly house with a great outdoor space, and fully stocked kitchen.

Quaint Southwest Mesilla Home - Pet Friendly

9.8 out of 10, Exceptional, (39)
"The home is very clean and yard is perfect for a dog. Wonderful property. "
The price is CA $87
CA $252 total
includes taxes & fees
Sep 9 - Sep 10
Quaint Southwest Mesilla Home - Pet Friendly

60-acre custom home with breathtaking views of city of Las Cruces & Organs!

10.0 out of 10, Exceptional, (20)
"Everything you need, plus more. They are the best hosts!!"
The price is CA $1,680
CA $2,716 total
includes taxes & fees
Sep 9 - Sep 10
60-acre custom home with breathtaking views of city of Las Cruces & Organs!

Southwest Gem just minutes from White Sands National Park

10.0 out of 10, Exceptional, (17)
"Beautifully decorated, modern, and very clean place to stay! I messed up the check out times (since we were doing a cross country trips and staying at multiple Vrbos), and the hosts were very accommodating and understanding. If you need a wonderful place near White Sands where you can also bring your dog, this is it! "
The price is CA $137
CA $373 total
includes taxes & fees
Sep 9 - Sep 10
Southwest Gem just minutes from White Sands National Park

4 Bedroom Contemporary Model Home

9.4 out of 10, Exceptional, (26)
"We had a great family weekend. Everything we needed was supplied and the house was very clean. "
The price is CA $137
CA $328 total
includes taxes & fees
Sep 10 - Sep 11
4 Bedroom Contemporary Model Home

Casa Sonoma | Spacious, Central Retreat | Peloton

10.0 out of 10, Exceptional, (40)
"Enjoyed our time here. Would definitely stay again. "
The price is CA $134
CA $404 total
includes taxes & fees
Sep 9 - Sep 10
Casa Sonoma | Spacious, Central Retreat | Peloton

Year Round Heated Pool, Hot Tub, Pet Friendly

10.0 out of 10, Exceptional, (50)
"Family together for graduation"
Year Round Heated Pool, Hot Tub, Pet Friendly

Las Cruces Southwest Charm with Pool, Hot Tub & Mountain Views

10.0 out of 10, Exceptional, (21)
"The home was great! Very relaxing and the hot tub was fantastic!"
Las Cruces Southwest Charm with Pool, Hot Tub & Mountain Views

Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces

9.0 out of 10, Wonderful, (2)
"Clean, updated, and equipped unit. AC was cold! Beautiful area. Close to highways, shopping, restaurants, etc. Had issues accessing due to Vrbo not providing access pin, but owner was on-site and let us in. Cooking pans weren’t great quality and food stuck. Sunday morning before 8am loud noise due to weed whacked, mowers, and blowers did not allow for rest. It also left my vehicle full of debris, weed cuttings, and lots of dust. Laundry appliances were used by others during our stay and access...
The price is CA $76
CA $180 total
includes taxes & fees
Sep 9 - Sep 10
Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces

Serene Spa hot tub Sanctuary with patio for the whole family

9.8 out of 10, Exceptional, (31)
"We had a comfortable, relaxing stay in this beautifully furnished property. It was perfect for our weekend getaway. "
The price is CA $137
CA $268 total
includes taxes & fees
Sep 19 - Sep 20
Serene Spa hot tub Sanctuary with patio for the whole family

Lovely 2-Bedroom Adobe Escape

9.8 out of 10, Exceptional, (24)
"This is our spot when we come to visit family in Las Cruces! Walking distance to Old Town Mesilla! Great place!"
Lovely 2-Bedroom Adobe Escape

Pulsar · Brand New Comfortable 4/3.5 Home Near Parks

9.8 out of 10, Exceptional, (37)
"Plenty of beds and space and a great central location to White Sands, Slot Canyon, and town. Thanks for making it easy!"
The price is CA $149
CA $466 total
includes taxes & fees
Sep 9 - Sep 10
Pulsar · Brand New Comfortable 4/3.5 Home Near Parks

Casa Alameda

9.4 out of 10, Exceptional, (8)
"Relaxing, quiet, perfect yard for our dogs! The location was convenient to all the attractions of Las Cruces & the host was super easy to communicate with. Thanks for a great place to stay during our visit!"
Casa Alameda

Private Oasis Near Old Mesilla - Home with an In-Ground Pool!

10.0 out of 10, Exceptional, (64)
"Very clean and centrally located "
Private Oasis Near Old Mesilla - Home with an In-Ground Pool!

Yucca House | Views, Jetted Bath, Central Retreat

10.0 out of 10, Exceptional, (32)
"Very cute house with wonderful view of the Organ Mtns "
The price is CA $127
CA $431 total
includes taxes & fees
Sep 9 - Sep 10
Yucca House | Views, Jetted Bath, Central Retreat

Centrally located Cozy RV with all the essentials in spacious secure gated area!

9.4 out of 10, Exceptional, (8)
"Great location and very convenient. Worked well for our stay. Clean and convenient - just whaat we needed. Host was very helpful. "
The price is CA $66
CA $129 total
includes taxes & fees
Sep 9 - Sep 10
Centrally located Cozy RV with all the essentials in spacious secure gated area!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Dona Ana Hotel Reviews

Find out more about Dona Ana

Find out more about Dona Ana

Everything you need to know about Dona Ana vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Dona Ana vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Dona Ana vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Dona Ana vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Dona Ana. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Dona Ana vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Dona Ana vacation rentals we have selected for you start as low as per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Dona Ana rentals

At Expedia, we put the best Dona Ana vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Dona Ana rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Dona Ana vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Dona Ana. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there vacation rentals in Dona Ana?

Yes, we have vacation rentals near well known local attractions in Dona Ana, or you can go with a more secluded option if you want a relaxing place to stay.

What are some of the best vacation home rentals that Dona Ana has to offer?

Cozy pet friendly house with a great outdoor space, and fully stocked kitchen. : Visitors like this Dona Ana vacation home rental. It offers a selection of games, a hot tub, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What can I see and do in Dona Ana?

Explore the area and family-friendly sights such as Museum of Nature & Science, or get out into nature at a spot like Dripping Springs Natural Area. Red Hawk Golf Club and Sonoma Ranch Golf Course are a couple of places you'll find in the larger area.

What are vacation rentals like in Dona Ana?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Dona Ana. Vacation rentals offer extras like WiFi and washers and dryers to help you enjoy your stay. If you're concerned about a sanitized environment, vacation rentals can offer a sense of safety away from public hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for a small group gathering.